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| Number | Title | Issue Date |
| 7410502 | Medical prosthetic devices having improved biocompatibility The invention relates to a medical prosthetic device having a metal material, such as titanium or an alloy thereof, where the surface parts of the metal material are coated with a layer of a corresponding hydroxide material, such as titanium hydroxide. Preferably, t... | 08/12/2008 |
| 7309359 | Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs Allogenic or xenogenic materials are used to provide intervertebral disc nucleus implants and/or annular plugs. The allogenic or xenogenic materials comprise natural disc annulus material, which may have a portion of the anterior longitudinal ligament attached. The ... | 12/18/2007 |
| 7144428 | Method for surface treatment of implants or prosthesis made of titanium or other materials A section of the implant is treated successively and separately with three different acids—hydrofluoric, sulphuric and hydrochloric acid— to create evenly distributed peaks on the surface and sufficient surface area. Plasma rich in growth factors is then applied... | 12/05/2006 |
| 7094286 | Inorganic bone adhesion agent and its use in human hard tissue repair The present invention discloses an inorganic bone adhesive and its use in human hard tissue repairs. The inorganic bone adhesive comprises basic compound, phosphate, calcium phosphate bone cement and retarder with the characteristics of rapid hydration rate and high... | 08/22/2006 |
| 7094418 | Crosslinkable macromers A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue implant or on the porous surface of a prosthetic device. The macromer s... | 08/22/2006 |
| 6736848 | Method and apparatus for using formable polymers for orthopedic support An orthopedic implant is formed from a sheet of moldable material such as a polymer or a bioresorbable material using an instrument. The material is heated above its glass transition temperature so that it can be formed into the desired shape of the implant. Then th... | 05/18/2004 |
| 6733505 | Apparatus and method for loading a prosthetic nucleus into a deployment cannula to replace the nucleus pulposus of an intervertebral disc An apparatus comprising a carrier cartridge, a deployment cannula releasably connected to the carrier cartridge, a folding die, and one or more force application members. A force applied on a prosthetic nucleus by the force application members in the direction of th... | 05/11/2004 |
| 6479565 | Bioactive ceramic cement The present invention provides a solution to the problems with known cements by providing a composition comprising (a) microscopic anhydrous pellets or particles containing the most important components of biological fluids or synthetic biological fluids ... | 11/12/2002 |
| 6410044 | Crosslinkable macromers A crosslinkable macromer system and related methods of preparing the system and using the system in the form of a crosslinked matrix between a tissue site and an implant article such as a tissue implant or on the porous surface of a prosthetic device. The... | 06/25/2002 |
| 6316091 | Method for preparing synthetic bone substitutes with controlled porosity The invention concerns a method for preparing macro-porous synthetic ceramics designed in particular for bone substitution. The invention also concerns macro-porous synthetic ceramics comprising pores of controlled dimensions, distributed in number and in... | 11/13/2001 |
| 6287341 | Orthopedic and dental ceramic implants A method for treating a bone defect is provided by identifying a bone site suitable for receiving an implant; and introducing a strongly resorbable, poorly crystalline apatitic calcium phosphate at the implant site, whereby bone is formed at the implant s... | 09/11/2001 |
| 6224913 | Conditioning of bioactive glass surfaces in protein containing solutions Conditioning of the surface of silica-based glass or ceramic by differential immersion in a serum protein-containing solution, and the resultant microporous Ca--P surface layer having serum-protein like organic molecules, as defined herein intermingled th... | 05/01/2001 |
| 6217614 | Process for treating bone tissue and corresponding implantable biomaterials The present invention concerns a process for treating bone tissue of animal or human origin, and a corresponding implantable biomaterial. According to the present invention, a fluid in the supercritical state is caused to penetrate throughout the bone tis... | 04/17/2001 |
| 6203844 | Precoated polymeric prosthesis and process for making same The present invention is directed to a polymeric prosthesis precoated with a bone cement compatible polymer. The bone cement compatible polymer coating, is provided by an activated powder mixture of polymethyl methacrylate and ultra high molecular weight ... | 03/20/2001 |
| 6189537 | Process for producing osteoinductive bone, and osteoinductive bone produced thereby The invention produces osteoinductive bone using a controlled-flow apparatus. The apparatus allows for the controlled extraction of undesirable constituents from a body tissue. The invention provides for the demineralization of ground bone particles or pi... | 02/20/2001 |
| 6110205 | Implant material having an excipient/active compound combination The present invention relates to porous implant materials which are loaded with an excipient/active compound combination, the excipient components used being oligomeric esters of polyhydric alcohols and -hydroxy acids.... | 08/29/2000 |
| 6051751 | Arthroplasty process for securely anchoring prostheses to bone, and arthroplasty products therefor A synovial prosthetic member includes a body having an articulating surface and an anchor surface, the articulating surface being configured for articulation with another articulating surface of a synovial joint, the anchor surface being configured for ce... | 04/18/2000 |
| 6005162 | Methods of repairing bone Methods are provided for repairing bone. In the subject methods, a flowable composition capable of setting under physiological conditions into an physiologically acceptable calcium phosphate mineral is administered to a bone repair site. Following adminis... | 12/21/1999 |
| 6002065 | Kits for preparing calcium phosphate minerals Setting times of calcium phosphate cement compositions are enhanced by the addition of phosphate or carbonate lubricant compositions. Methods for preparing the cement compositions are provided.... | 12/14/1999 |
| 5980573 | Method and apparatus for fighting infection and maintaining joint spacing in a prosthesis implant area A temporary non-weight bearing prosthesis to be placed inside an implant area of a joint replacement patient. The prosthesis is impregnated with an antibiotic agent which leaches out to the surrounding tissue to fight infection in the implant area. While ... | 11/09/1999 |
| 5980974 | Coated orthopaedic implant components An improved coated orthopaedic implant component is disclosed. The implant may be coated with platinum, iridium or other metals for improved characteristics. Ion beam coating orthopaedic parts by ion implanting the parts with zirconium ions while the part... | 11/09/1999 |
| 5977432 | Process for cleaning bone grafts using centrifugal force and bone grafts produced thereby A process for removing essentially all bone marrow from a cut bone graft and the cut bone graft produced thereby. A large substantially intact bone is selected and excess cartilage and associated soft tissues are removed from the surface of the bone. The ... | 11/02/1999 |
| 5934287 | Implant with bioactive particles stuck and method of manufacturing the same An implant includes a main body member having bio-compatibility, and particles formed of bioactive material and dispersedly provided at the surface of an embedded section of the main body member. Each of the particles has a part embedded in the embedded p... | 08/10/1999 |
| 5897592 | Implantable articles with as-cast macrotextured surface regions and method of manufacturing the same An implantable article having on at least a portion of its exterior surface an integral, as-cast macrotextured surface with macropores having undercut edge profiles. A complex macrotextured surface is provided by forming a casting mold so that the mold ha... | 04/27/1999 |
| 5846484 | Pressure flow system and method for treating a fluid permeable workpiece such as a bone A pressure flow system and method for its use are provided for contacting the interior of a fluid permeable, e.g., porous, workpiece. The system includes a fluid pressure chamber having an inlet port and an opening formed in one of the chamber walls. An a... | 12/08/1998 |
| 5837752 | Semi-interpenetrating polymer networks Compositions for bone repair have been developed based on linear hydrophobic degradable polymers and monomers or macromers, at least one of which includes an anhydride linkage. The monomers and/or macromers crosslink each other but not to the linear polym... | 11/17/1998 |
| 5824084 | Method of preparing a composite bone graft The present invention provides a new and improved method for preparing a composite bone graft. The method includes providing a bone marrow aspirate suspension and passing the bone marrow aspirate suspension through a porous, biocompatible, implantable sub... | 10/20/1998 |
| 5795353 | Joint resurfacing system A system for resurfacing orthopedic joints by arthroscopic means. The system involves a method that includes the delivery of a curable biomaterial, and the use of minimally invasive means to prepare an injury site, and then deliver, cure and shape a curab... | 08/18/1998 |
| 5766247 | Process for producing a bioimbedding material A bioimbedding material comprising a mixture of ultrafine hydroxyapatite powder having a particle size of 2 μm or less, and a polymer or oligomer, which can function as a tissue substitute for a long time in a living organism, without causing inflammatio... | 06/16/1998 |
| 5746963 | Cold flow control This is basically an Engineering design of a means to control the stability and or resistivity of certain materials subject to Cold Flow without materially decreasing the material's normal function. This does not require additional thickness and/or harden... | 05/05/1998 |
| 5702456 | Implant having reduced generation of wear particulates A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components. The method includes the steps of placing the total joint orthopaedic implant in ... | 12/30/1997 |
| 5684061 | Bone inducing material A bone inducing material comprising a piezoelectric porous membrane having through-holes of an average pore size of about 0.1 to 5 μm is disclosed. When the bone inducing material according to the present invention is used, bone is rapidly regenerated, a... | 11/04/1997 |
| 5672284 | Method of making orthopaedic implant by welding A method of forming an orthopaedic implant having a porous surface, the method including the steps of providing a porous surface including a porous layer attached to a substantially solid layer; positioning the porous layer on the orthopaedic implant; pro... | 09/30/1997 |
| 5660850 | Use of autologous dermal fibroblasts for the repair of skin and soft tissue defects The application concerns a device for repairing a dermal defect in a subject comprising: a) a hypodermic syringe having a syringe chamber, a piston disposed therein, and an orifice communicating with the chamber; b) a suspension comprising: 1) dermal fibr... | 08/26/1997 |
| 5658334 | Implantable articles with as-cast macrotextured surface regions and method of manufacturing same An implantable article having on at least a portion of its exterior surface an integral, as-cast macrotextured surface with macropores having undercut edge profiles. A complex macrotextured surface is provided by forming a casting mold so that the mold ha... | 08/19/1997 |
| 5593719 | Treatments to reduce frictional wear between components made of ultra-high molecular weight polyethylene and metal alloys The present invention provides methods for modifying surfaces made from metal alloy and/or UHMWPE, preferably surfaces which are frictionally engaged, e.g., in an orthopaedic implant. The methods of the present invention reduce the coefficient of friction... | 01/14/1997 |
| 5591398 | Method for sterilizing bone grafts A method and apparatus for sterilizing bone grafts, wherein the bone graft together with a quantity of sterile liquid sufficient to cover the bone graft is initially heated at a given sterilizing temperature for a constant first period of time, and is sub... | 01/07/1997 |
| 5573771 | Medicinal bone mineral products The invention provides a purified particulate bone mineral product for use in medicine, the particles of said mineral being substantially free from all endogenous organic material and having at least at the surface thereof resorbable, physiologically comp... | 11/12/1996 |
| 5571188 | Process for treating a metallic surgical implant Metallic surgical implant materials having improved strength of connection with bone are produced when the implants are treated prior to implantation with an aqueous solution of sodium fluoride.... | 11/05/1996 |
| 5571187 | Implant having a metallic porous surface An implant comprises a plastic body and a metallic, porous surface securely fixed to the body. The porous surface is attached to the body by infiltration of the body into the porous surface such that the body and porous surface interdigitate. A filler mat... | 11/05/1996 |
