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| Number | Title | Issue Date |
| 7931692 | Implant derived from bone An implant which is particularly suitable for the repair and/or replacement of a skeletal joint, e.g., a vertebral joint, includes a unit of monolithic bone possessing at least one demineralized region exhibiting properties of flexibility and resilience, the deminer... | 04/26/2011 |
| 7837740 | Two piece cancellous construct for cartilage repair The invention is directed toward a cartilage repair assembly comprising a shaped allograft two piece construct with a demineralized cancellous cap and a mineralized cylindrical base member defining a blind bore with a through going transverse bore intersecting the b... | 11/23/2010 |
| 7753963 | Demineralized bone-derived implants Selectively demineralized bone-derived implants are provided. In one embodiment, a bone sheet for implantation includes a demineralized field surrounding mineralized regions. In another embodiment, a bone defect filler includes a demineralized cancellous bone sectio... | 07/13/2010 |
| 7670384 | Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone Formed compositions for application to a bone surface of a human or animal subject, comprising: a bone material; and a carrier comprising denatured demineralized bone, where the composition is formed into a shape suitable for administration to the bone. Methods are ... | 03/02/2010 |
| 7658768 | Bone graft substitute composition Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first mixture having calcium sulfate hemihydrate and a plasticizing material t... | 02/09/2010 |
| 7608113 | Demineralized bone implants Selectively demineralized bone-derived implants are provided. In one embodiment, a bone sheet for implantation includes a demineralized field surrounding mineralized regions. In another embodiment, a bone defect filler includes a demineralized cancellous bone sectio... | 10/27/2009 |
| 7488348 | Cartilage allograft plug The invention is directed toward a cartilage repair assembly comprising a cylindrically shaped allograft structure of subchondral bone with an integral overlying smaller diameter cartilage cap which is treated to remove cellular debris and proteoglycans. The shaped ... | 02/10/2009 |
| 7427293 | Osteochondral plug graft, kit and method Each of an osteochondral plug graft and a kit comprises a trapezoid shaped construct configured for osteochondral implanting. An osteochondral regeneration method comprises forming a recipient socket in a chondral area of an articular joint in need of repair; harves... | 09/23/2008 |
| 7393493 | Crosslinkable polymeric materials and their applications The present invention relates to a novel composition for dental, orthopedic and drug delivery purpose. Specifically, it relates to composition comprising an admixture of a resorbable bone substitute and a crosslinkable prepolymer. It also relates to the composition ... | 07/01/2008 |
| 7371410 | Bone graft substitute composition A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance. A bone graft substitute composition can include calcium sulfate, demineralized bone matrix, cancellous bone, a plasticizing substance, an... | 05/13/2008 |
| 7371409 | Bone graft substitute composition A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance. A bone graft substitute composition can include calcium sulfate, demineralized bone matrix, cancellous bone, a plasticizing substance, an... | 05/13/2008 |
| 7371408 | Bone graft substitute composition A bone graft substitute composition comprising calcium sulfate; a mixing solution selected from the group consisting of sterile water, sodium chloride, phosphate buffered saline, potassium chloride, and sodium sulfate; and a plasticizing substance selected from the ... | 05/13/2008 |
| 7368065 | Implants with textured surface and methods for producing the same Compositions and methods are provided for preparing a metal substrate having a uniform textured surface with a plurality of indentations with a diameter in the nanometer and micrometer range. The textured surface is produced by exposing the substrate to an etching f... | 05/06/2008 |
| 7361195 | Cartilage repair apparatus and method An orthopaedic device for repairing and regenerating cartilage includes a plug configured to be positioned in a hole formed in the cartilage and an anchor configured to support the plug. One or both of the plug and the anchor may be formed from naturally occurring e... | 04/22/2008 |
| 7351262 | Bone implants and methods of making same The present invention provides an implant for use in fusing adjacent bony structures. The implant comprises a plurality of pieces of bone and a flexible mechanism including one or more flexible, elongate, biocompatible connectors interconnecting the pieces of bone. | 04/01/2008 |
| 7338757 | Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced The invention provides methodologies and apparatus for producing acellular soft-tissue implants, both in small quantities and in commercializable quantities. Such soft-tissue implants include vascular graft substitutes. An acellular graft is produced by subjecting t... | 03/04/2008 |
| 7323193 | Method of making demineralized bone particles Demineralized bone particles are obtained by demineralizing whole bone and thereafter subdividing the demineralized bone to provide the demineralized bone particles. ... | 01/29/2008 |
| 7323011 | Cortical and cancellous allograft cervical fusion block A sterile composite bone graft for use in implants comprising a T shaped cortical bone load bearing member mated to a cancellous member. The crosspiece of the T defines an inner planar surface and dove tail shaped mating member extends outward from the inner planar ... | 01/29/2008 |
| 7320728 | Rod-shaped apatite crystals having a specific length-to-width ratio The rod-shaped apatite crystals of the formula Ca5(PO4)3(OH)xFy have the following features a) the length-to-breadth ratio of the crystals is at least ≧5 and b) x+y=1, where if x or y... | 01/22/2008 |
| 7318841 | Synthesis of calcium phosphates by mechano-chemical process A low crystallinity calcium phosphate powder is prepared by mechanically grinding a calcium phosphate solid under grinding forces local heating sufficient to mechanically alloy the calcium phosphate solid and reduce the crystalline domains of the calcium phosphate s... | 01/15/2008 |
| 7300465 | Intervertebral allograft spacer An allogenic intervertebral implant for fusing vertebrae is disclosed. The implant is a piece of allogenic bone conforming in size and shape with a portion of an end plate of a vertebra. The implant has a wedge-shaped profile to restore disc height and the natural c... | 11/27/2007 |
| 7291179 | Bone graft substitute composition Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first mixture having calcium sulfate hemihydrate and a plasticizing material t... | 11/06/2007 |
| 7291169 | Cartilage implant A cartilage implant for replacing a portion of the cartilage adjacent to a skeletal joint is presented. ... | 11/06/2007 |
| 7288114 | Medical implant The medical implant is constructed of a fiber reinforced plastic. That fibers (50a, 50b) are generally aligned in layers (C, D, E), wherein the fibers of at least two different layers having different orientations. The fibers are long and... | 10/30/2007 |
| 7255712 | Bone growth promoting implant A stem-like bone implant includes longitudinal structural members and tension cables that provide curvature control and support, and rigidity against bending and buckling. The longitudinal structural members and tension cables may become an integral part of a compos... | 08/14/2007 |
| 7252685 | Fusion implant and method of making same The present invention provides an implant for use in fusing adjacent bony structures. The implant comprises at least one structural member combined with at least one flexible planar member to retain the at least one structural member to form the implant. ... | 08/07/2007 |
| 7238204 | Shock-absorbing intervertebral implant The invention relates to an intervertebral implant comprising a spacer designed to be applied between two spinous processes of two vertebrae. The spacer comprises: two elements (10, 12) made of a first material, and each presenting a first end (10a,... | 07/03/2007 |
| 7226482 | Multipiece allograft implant An allogenic implant for use in intervertebral fusion is formed from two parts. The first part, composed of cortical bone, provides mechanical strength to the implant, allowing the proper distance between the vertebrae being treated to be maintained. The second part... | 06/05/2007 |
| 7217290 | Surgical devices containing a heat bondable material with a therapeutic agent Surgical devices such as implants or suture fastenings are assembled from a plurality of discrete components, one of which components includes a heat bondable plastic material for bonding the components together. At least two components are bonded to each other by t... | 05/15/2007 |
| 7205337 | End-capped polymers and compositions containing such compounds End-capped polymers, methods for making those end-capped polymers, compositions containing those end-capped polymers, and methods for using those compositions are disclosed. One of the disclosed end-capped copolymers has the formula (I): | 04/17/2007 |
| 7201774 | Artificial intervertebral disc replacements incorporating reinforced wall sections An Artificial Disc Replacement (ADR) includes a body and/or outer wall that is fortified, reinforced, stiffened or otherwise strengthened with a higher durometer, for example, where it rests against a weakened or deficient area of the annulus fibrosis (AF). The “l... | 04/10/2007 |
| 7201776 | Artificial intervertebral disc replacements with endplates An artificial disc replacement (ADR) includes a pair of opposing endplate components, each attached to one of the upper and lower vertebrae, a cushioning component disposed between the endplate components; and a filler material contained within the cushioning compon... | 04/10/2007 |
| 7192447 | Intervertebral implant A vertebral implant for fusing adjacent vertebrae or for replacing vertebral bodies is disclosed. The implant is a biocompatible metal, resorbable, or radiolucent implant conforming substantially in size and shape with an end plate of a vertebra. The implant prefera... | 03/20/2007 |
| 7179299 | Osteoimplant and method for making same A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a depth of at least about 100 microns; and, configuring the monolithic s... | 02/20/2007 |
| 7163560 | Method for graftless spinal fusion A graftless spinal implant for mechanically attaching two adjacent vertebrae includes a body having first and second opposite surfaces. The first and second surfaces include at least one protruding member for securing the body to adjacent vertebrae, wherein the exte... | 01/16/2007 |
| 7162850 | Method of packaging a bone allograft intended for a spinal fusion procedure A system and method of packaging a bone allograft for use in a future medical procedure in which the bone allograft is stored in a saturated saline solution in an airtight container. The saline solution keeps the allograft hydrated and may be saturated with a combin... | 01/16/2007 |
| 7160333 | Reinforced small intestinal submucosa Bioprosthetic devices for soft tissue attachment, reinforcement, or construction are provided. The devices comprise a sheet of naturally occurring extracellular matrix and a sheet of synthetic mesh coupled to the naturally occurring extracellular matrix portion.... | 01/09/2007 |
| 7153482 | Rod shaped apatite crystals having a specific length-to-width ratio The rod-shaped apatite crystals of the formula Ca5(PO4)3(OH)xFy have the following features a) the length-to-breadth ratio of the crystals is at least ≧5 and b) x+y=1, where if x or y... | 12/26/2006 |
| 7144428 | Method for surface treatment of implants or prosthesis made of titanium or other materials A section of the implant is treated successively and separately with three different acids—hydrofluoric, sulphuric and hydrochloric acid— to create evenly distributed peaks on the surface and sufficient surface area. Plasma rich in growth factors is then applied... | 12/05/2006 |
| 7141072 | Method for promoting regeneration of surface cartilage in a damaged joint using multi-layer covering A method of promoting regeneration of surface cartilage of a joint includes the steps of covering the area to be treated with a patch which includes a sheet of collagen membrane material. The collagen membrane material has at least one barrier layer to prevent passa... | 11/28/2006 |
