...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 8034117 | Bone replacement material Bone replacement material to be used by being packed into a bone defective part, wherein the bone replacement material consists essentially of a calcium phosphate based compound and is formed into a pellet and satisfies both of the following conditions (I) and (II):... | 10/11/2011 |
| 8012218 | Medical bone prosthetic material and process for producing the same There is disclosed a bone substitute material for medical use which satisfies all the requirements of (1) no histotoxicity, (2) osteoconductivity, (3) bone replacement capability, and (4) mechanical strength necessary for a bone reconstruction operation. The bone su... | 09/06/2011 |
| 7959683 | Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation A composition for spinal disc repair comprising a plurality of uniformly shaped demineralized cancellous bone pieces ranging in size from about 2.0 mm to about 4.0 mm loaded into a porous mesh container with the cancellous bone pieces being treated so that they are ... | 06/14/2011 |
| 7959682 | Method for producing bone substitution material In order to provide a bone substitution material which enables mechanical stability and long-term in-vivo biocompatibility which can also be used for guided bone healing, the invention provides a method comprising the steps of providing a starting material comprisin... | 06/14/2011 |
| 7879107 | Composition and method for inducing bone growth and healing A composition and method for inducing bone growth and healing is provided. The composition is useful for promoting new bone synthesis, and to enhance the mechanical stability and longevity of orthopaedic implants. The composition includes a bone endogenous material ... | 02/01/2011 |
| 7766972 | Synthetic, malleable bone graft substitute material The invention includes a synthetic bone substitute material suitable for use as a replacement for cancellous bone in a bone graft composition, the material comprising a reticulated framework of interconnecting bioceramic struts defining an interconnecting interstiti... | 08/03/2010 |
| 7621963 | Composite bone graft material A bone graft material comprising about 50-90% quickly bioresorbable porogen particles and about 10-50% of a calcium matrix material. A bioactive substance can be included in the matrix material, the porogen particles, or both. Commercial packages containing the bone... | 11/24/2009 |
| 7531005 | Biodegradable composite material for tissue repair There is described a biodegradable composite material for tissue repair comprising a water-soluble glass, preferably as glass fibers and/or particles in the form of a matrix, impregnated with a biodegradable polymer. An especially preferred polymer is poly ε-caprol... | 05/12/2009 |
| 7419680 | Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate Compositions useful in the prevention and treatment of osteoporosis and for bone and fracture repair. Slow-releasing calcium phosphate-based materials are disclosed, incorporating Mg, Zn, F and carbonate, which will promote bone formation and inhibit bone resorption... | 09/02/2008 |
| 7393405 | Hydraulic cement based on calcium phosphate for surgical use A hydraulic cement is based on calcium phosphate for surgical use, and includes three components. The first component includes α-tricalcium phosphate powder particles. The second, component includes calcium sulphate dehydrate. The third component includes water. Fu... | 07/01/2008 |
| 7371410 | Bone graft substitute composition A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance. A bone graft substitute composition can include calcium sulfate, demineralized bone matrix, cancellous bone, a plasticizing substance, an... | 05/13/2008 |
| 7371409 | Bone graft substitute composition A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance. A bone graft substitute composition can include calcium sulfate, demineralized bone matrix, cancellous bone, a plasticizing substance, an... | 05/13/2008 |
| 7371408 | Bone graft substitute composition A bone graft substitute composition comprising calcium sulfate; a mixing solution selected from the group consisting of sterile water, sodium chloride, phosphate buffered saline, potassium chloride, and sodium sulfate; and a plasticizing substance selected from the ... | 05/13/2008 |
| 7353153 | Method and system for modeling bone structure The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model allows for the assessment of bone deformations, computation of strains... | 04/01/2008 |
| 7318841 | Synthesis of calcium phosphates by mechano-chemical process A low crystallinity calcium phosphate powder is prepared by mechanically grinding a calcium phosphate solid under grinding forces local heating sufficient to mechanically alloy the calcium phosphate solid and reduce the crystalline domains of the calcium phosphate s... | 01/15/2008 |
| 7309361 | Biologic modular tibial and femoral component augments for use with total knee arthroplasty The use of biologic and/or biologically reabsorbable materials to provide temporary stability after a surgical joint procedure is provided. Exemplary embodiments of the invention provide biologic and/or biologically reabsorbable cam and/or post linings mounted to re... | 12/18/2007 |
| 7294187 | Rapid-hardening calcium phosphate cement compositions A bone or dental implant material in the form of a paste includes a mixture of calcium phosphate and/or calcium-containing powders and a solution that is (1) an acidic calcium phosphate solution saturated with respect to one or more calcium phosphate compounds, (2) ... | 11/13/2007 |
| 7291179 | Bone graft substitute composition Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first mixture having calcium sulfate hemihydrate and a plasticizing material t... | 11/06/2007 |
| 7283940 | Multidirectional morphology and mechanics of osteonic lamellae The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model allows for the assessment of bone deformations, computation of strains... | 10/16/2007 |
| 7247171 | Modular hip implants An implant for improved engagement between modular components is provided. The implant includes a body member for insertion, in use, in a natural femoral neck; and a rod for insertion, in use, in the intramedullary canal of a femur. The body member has a first engag... | 07/24/2007 |
| 7241316 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant comprising collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be â... | 07/10/2007 |
| 7238209 | Bone replacement material A bone replacement material for use in a treatment for repairing a vertebral body compression fracture is formed into a pellet having a roughly polyhedral shape. Each pellet having the roughly polyhedral shape has a pair of opposite surfaces, in which one of the opp... | 07/03/2007 |
| 7235107 | Devices and methods for treating defects in the tissue of a living being An implantable material for deployment in select locations or select tissue for tissue regeneration is disclosed. The implant comprises collagen, ceramics, and or other bio-resorbable materials or additives, where the implant may also be used for therapy delivery. A... | 06/26/2007 |
| 7229545 | Process for the coating for metallic implant materials A biomimetically produced bone-analogous coating, comprising organic and inorganic main constituents, is suitable for coating metallic implant materials of any desired surfaces. The coating comprises a collagen matrix mineralized with calcium phosphate. ... | 06/12/2007 |
| 7212958 | Method and system for modelling bone structure The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model allows for the assessment of bone deformations, computation of strains... | 05/01/2007 |
| 7208013 | Composite surgical devices Surgical devices such as implants or suture fastenings are assembled from a plurality of discrete components, one of which components includes a heat bondable plastic material for bonding the components together. At least two components are bonded to each other by t... | 04/24/2007 |
| 7203628 | Manufacturing system and method A method for manufacturing an object having a potential {x} that is generated in response to a field {f} applied thereto. A computerized mathematical model of the object is generated by discretizing a geometric model of the object into a plurality of finite elements... | 04/10/2007 |
| 7189263 | Biocompatible bone graft material Biocompatible bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities. ... | 03/13/2007 |
| 7179299 | Osteoimplant and method for making same A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a depth of at least about 100 microns; and, configuring the monolithic s... | 02/20/2007 |
| 7172629 | Osteogenic paste compositions and uses thereof Described are osteogenic paste compositions with enhanced osteoinductive properties for use in bone repair. Compositions comprising a quickly resorbable paste carrier, a more slowly resorbed mineral matrix, and Bone Morphogenetic Protein (BMP) or other osteogenic fa... | 02/06/2007 |
| 7173079 | Casting material for producing casting molds for casting high-melting point materials The casting-mold material designed to manufacture casting molds used in casting high melting-point substances. The casting mold formed from a powder component containing magnesium oxide and aluminum oxide and a liquid component. The powder component additionally con... | 02/06/2007 |
| 7166133 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant comprising collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be â... | 01/23/2007 |
| 7163965 | Process for producing porous composite materials This invention relates to a process for producing porous and composite materials comprising steps of: freezing a complex containing at least one calcium salt selected from calcium carbonate, calcium phosphate, and hydroxyapatite and collagen, at least a part of whic... | 01/16/2007 |
| 7162850 | Method of packaging a bone allograft intended for a spinal fusion procedure A system and method of packaging a bone allograft for use in a future medical procedure in which the bone allograft is stored in a saturated saline solution in an airtight container. The saline solution keeps the allograft hydrated and may be saturated with a combin... | 01/16/2007 |
| 7163560 | Method for graftless spinal fusion A graftless spinal implant for mechanically attaching two adjacent vertebrae includes a body having first and second opposite surfaces. The first and second surfaces include at least one protruding member for securing the body to adjacent vertebrae, wherein the exte... | 01/16/2007 |
| 7156880 | Devices and methods for treating defects in the tissue of a living being An implantable material for deployment in select locations or select tissue for tissue regeneration is disclosed. The implant comprises collagen, ceramics, and or other bio-resorbable materials or additives, where the implant may also be used for therapy delivery. A... | 01/02/2007 |
| 7147666 | Monolithic implants with openings A monolithic bioresorbable implant includes optimally designed openings to treat tissue disorders or drug delivery. Preferably, the implant is made from calcium salts. A method of filling a recipient treatment site includes the step of disposing the monolithic biore... | 12/12/2006 |
| 7144428 | Method for surface treatment of implants or prosthesis made of titanium or other materials A section of the implant is treated successively and separately with three different acids—hydrofluoric, sulphuric and hydrochloric acid— to create evenly distributed peaks on the surface and sufficient surface area. Plasma rich in growth factors is then applied... | 12/05/2006 |
| 7140882 | Method of producing low molecular weight chitin/chitosan and method of producing an osteoconduction substance By irradiating 60Co γ ray to chitin/chitosan, chitin/chitosan having high molecular weight is separated or decomposed into low molecular weight chitin/chitosan. A method of producing an osteoconduction substance comprises the steps of irradiating 60... | 11/28/2006 |
| 7128967 | Calcium phosphate-synthetic resin-metal composite body and method for production thereof A calcium phosphate-synthetic resin-metal composite body produced by pressing a metal member, calcium phosphate particles (or calcium phosphate particles and a calcium phosphate block) and synthetic resin particles I, which are at least partially cross-linked in adv... | 10/31/2006 |