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| Number | Title | Issue Date |
| 8163031 | Composites and methods for treating bone A system and method for treating bone abnormalities including vertebral compression fractures and the like. In one method, an elastomeric composite implant body is inserted into bone. A rigid insert can be inserted into the elastomeric composite implant body. The el... | 04/24/2012 |
| 8163030 | Biocompatible bone implant compositions and methods for repairing a bone defect Moldable bone implants for use in a bone defect or wound include a plurality of biocompatible granules and a biocompatible polymer that together form an implant mass. The polymer is softened with a plasticizer to make the implant mass moldable. The plasticizer can d... | 04/24/2012 |
| 8163032 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may includ... | 04/24/2012 |
| 8137408 | Autologous bone graft material This invention relates to a musculoskeletogenic MSG graft composite made from whole bone marrow aspirate BMA having native levels of musculoskeletal progenitor cells MSPCs, comprising: a) a suspension of fractionated BMA comprising: i) MSPC... | 03/20/2012 |
| 8002843 | Polyurethanes for osteoimplants Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined... | 08/23/2011 |
| 7892291 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may includ... | 02/22/2011 |
| 7887598 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be “... | 02/15/2011 |
| 7842097 | Tissue repair matrix A porous three-dimensional tissue repair matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix. ... | 11/30/2010 |
| 7833278 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. ... | 11/16/2010 |
| 7731756 | Biodegradable biocompatible implant There is described a biocompatible implant for the filling of a cavity in a living organism such as, for example, a bone defect or an extraction wound, comprising an open porous scaffold and/or a composite matrix comprising a plurality of inorganic or synthetic gran... | 06/08/2010 |
| 7544212 | Bone implant composite A bone implant composite comprising a collagen matrix and a calcium-based mineral, the calcium-based mineral having a particle size of 25-2000 μm and being interspersed in the collagen matrix; wherein the bone implant composite contains 3-60% by weight the collagen... | 06/09/2009 |
| 7531004 | Pliable conformable bone restorative A pliable bone restorative having an osteoconductive foam that at least partially surrounds a biocompatible mesh and the foam comprises a biocompatible, resorbable polymer and calcium phosphate. ... | 05/12/2009 |
| 7381224 | Bone implant composite A bone implant composite comprising a collagen matrix and a calcium-based mineral, the calcium-based mineral having a particle size of 25-2000 μm and being interspersed in the collagen matrix; wherein the bone implant composite contains 3-60% by weight the collagen... | 06/03/2008 |
| 7371409 | Bone graft substitute composition A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance. A bone graft substitute composition can include calcium sulfate, demineralized bone matrix, cancellous bone, a plasticizing substance, an... | 05/13/2008 |
| 7371410 | Bone graft substitute composition A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance. A bone graft substitute composition can include calcium sulfate, demineralized bone matrix, cancellous bone, a plasticizing substance, an... | 05/13/2008 |
| 7371408 | Bone graft substitute composition A bone graft substitute composition comprising calcium sulfate; a mixing solution selected from the group consisting of sterile water, sodium chloride, phosphate buffered saline, potassium chloride, and sodium sulfate; and a plasticizing substance selected from the ... | 05/13/2008 |
| 7354452 | Spinal bone implant Implantable devices useful for creating bony fusion particularly in intervetebral spinal fusion. The device is formed of bone and has a body portion with an upper flange member and an opposite lower flange member extending from the body portion. The upper and lower ... | 04/08/2008 |
| 7353153 | Method and system for modeling bone structure The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model allows for the assessment of bone deformations, computation of strains... | 04/01/2008 |
| 7351423 | Musculo-skeletal implant having a bioactive gradient This invention relates to an implant for a musculoskeletal defect having a bioactive agent having a concentration gradient. ... | 04/01/2008 |
| 7348020 | Invasive medical device, especially for guided tissue regeneration Biodegradable invasive medical device, in particular for guided tissue regeneration, which device comprises a biodegradable polymer, composed of a thermoplastic and/or thermosetting polymer admixed to a solvent that is miscible with any aqueous and/or aqueous alcoho... | 03/25/2008 |
| 7335232 | Method for repairing bone A method for repairing bone in a bone cavity delimited by healthy bone faces, and from which traumatized bone has been excised, comprises adjusting a flexible, biocompatible mesh fabric tube to fit the bone cavity and contact the healthy bone faces and filling the m... | 02/26/2008 |
| 7335381 | Transplantable particulate bone composition having high osteoinductive capacity and methods for making and using same A particulate bone of defined sizes which has a unique property of direct bone osteoinduction without going through endochondral ossification stage is disclosed. The bone is not subjected to chemical extraction or decalcification. This allows for the retention of al... | 02/26/2008 |
| 7332195 | Chemical vapor deposition method Method for densifying a porous carbon preform (5). The method includes the steps of: (a) providing the apparatus (11); (b) charging the apparatus (11) with a plurality of stacks of annular porous carbon preforms (5), the preforms being se... | 02/19/2008 |
| 7309361 | Biologic modular tibial and femoral component augments for use with total knee arthroplasty The use of biologic and/or biologically reabsorbable materials to provide temporary stability after a surgical joint procedure is provided. Exemplary embodiments of the invention provide biologic and/or biologically reabsorbable cam and/or post linings mounted to re... | 12/18/2007 |
| 7300465 | Intervertebral allograft spacer An allogenic intervertebral implant for fusing vertebrae is disclosed. The implant is a piece of allogenic bone conforming in size and shape with a portion of an end plate of a vertebra. The implant has a wedge-shaped profile to restore disc height and the natural c... | 11/27/2007 |
| 7299506 | Bedsore prevention kit A bedsore prevention kit includes a finger grip that includes a tubular member having a first end and a second end. A strap is attached to and extends between the first and second ends. The strap is extendable over a plurality of fingers and the tubular member is po... | 11/27/2007 |
| 7291345 | Formable and settable polymer bone composite and method of production thereof A composite osteoimplant. The osteoimplant includes a polymer and bone-derived particles. The composite is adapted and constructed to be formable during or immediately prior to implantation and to be set after final surgical placement. ... | 11/06/2007 |
| 7291169 | Cartilage implant A cartilage implant for replacing a portion of the cartilage adjacent to a skeletal joint is presented. ... | 11/06/2007 |
| 7291179 | Bone graft substitute composition Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first mixture having calcium sulfate hemihydrate and a plasticizing material t... | 11/06/2007 |
| 7288114 | Medical implant The medical implant is constructed of a fiber reinforced plastic. That fibers (50a, 50b) are generally aligned in layers (C, D, E), wherein the fibers of at least two different layers having different orientations. The fibers are long and... | 10/30/2007 |
| 7283940 | Multidirectional morphology and mechanics of osteonic lamellae The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model allows for the assessment of bone deformations, computation of strains... | 10/16/2007 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7264634 | Method and instrumentation for osteochondral repair using preformed implants Osteochondral repair of damaged articular joint surfaces is achieved using implants in the form of cylindrical osteochondral plugs. The plugs have an articular surface formed on at least one end. If articular surfaces are provided on both ends of the implant, the ar... | 09/04/2007 |
| 7252833 | Calcium phosphate cements comprising an osteoclastogenic agent Methods and compositions are provided for producing flowable compositions, e.g. pastes, that set into calcium phosphate products that include an osteoclastogenic agent. In the subject methods, dry reactants that include a calcium source and a phosphate source are co... | 08/07/2007 |
| 7244301 | Heat generating biocompatible ceramic materials An injectable heat generating biocompatible ceramic compositions based on hydraulic calcium aluminate, which can be used for therapeutic treatment in vivo, such as tumour treatment, pain control, vascular treatment, drug activation etc, when curing in situ, and whic... | 07/17/2007 |
| 7241486 | Bone grafting materials The present invention relates to porous bone filling materials prepared by sintering bioactive glass fibers in order to achieve a three dimensional block with interconnecting porosity. Due to the osteoconductive properties the bioactive glass fibers, in block form a... | 07/10/2007 |
| 7241316 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant comprising collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be â... | 07/10/2007 |
| 7235107 | Devices and methods for treating defects in the tissue of a living being An implantable material for deployment in select locations or select tissue for tissue regeneration is disclosed. The implant comprises collagen, ceramics, and or other bio-resorbable materials or additives, where the implant may also be used for therapy delivery. A... | 06/26/2007 |
| 7226482 | Multipiece allograft implant An allogenic implant for use in intervertebral fusion is formed from two parts. The first part, composed of cortical bone, provides mechanical strength to the implant, allowing the proper distance between the vertebrae being treated to be maintained. The second part... | 06/05/2007 |
| 7212958 | Method and system for modelling bone structure The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model allows for the assessment of bone deformations, computation of strains... | 05/01/2007 |