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| Number | Title | Issue Date |
| 7300662 | Drug/drug delivery systems for the prevention and treatment of vascular disease A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f... | 11/27/2007 |
| 7229473 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 06/12/2007 |
| 7223286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/29/2007 |
| 7217286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/15/2007 |
| 6890352 | Vessel valve A vessel valve including a sleeve or ring having a central opening and openable and closeable flap elements intended to allow the flow of blood through the central opening in one direction, whereas the flap elements are designed as circle segments, and the sector an... | 05/10/2005 |
| 6645244 | Mechanical heart valve prosthesis An improved artificial mechanical heart valve prosthesis having an improved leaflet hinge mechanism which improves washing of the hinge recess, reduces leaflet closing impact force and decreases noise and wear. A generally annular valve body having an ann... | 11/11/2003 |
| 6007577 | Prosthetic heart valve with increased valve lumen A heart valve prosthesis having a valve housing providing a lumen therethrough. The valve housing has a first annulus on one end and a second annulus on the other end spaced apart from the first annulus. A suture cuff is used for attaching the valve housi... | 12/28/1999 |
| 5919226 | Mechanical heart valve prosthesis An improved artificial mechanical heart valve prosthesis having an improved leaflet hinge mechanism which improves washing of the hinge recess, reduces leaflet closing impact force and decreases noise and wear. A generally annular valve body having an ann... | 07/06/1999 |
| 5908452 | Prosthetic heart valve with improved blood flow A prosthetic heart valve is shown which incorporates a valve body design and leaflet pivot arrangements that minimize turbulence and shear stresses having a tendency to generate thrombosis. A valve body having an axially curved entrance that is smoothly j... | 06/01/1999 |
| 5772694 | Prosthetic heart valve with improved blood flow A prosthetic heart valve is shown which incorporates a valve body design and leaflet pivot arrangements that minimize turbulence and shear stresses having a tendency to generate thrombosis. A valve body having an axially curved entrance that is smoothly j... | 06/30/1998 |
| 5741328 | Pivot for mechanical heart valve prothesis A pivot mechanism for a mechanical heart prosthesis includes internal recesses on an inside surface of an orifice ring having portions thereof near the recesses tapered to reduce flow resistance and minimize turbulence to improve hemodynamic efficiency of... | 04/21/1998 |
| 5641324 | Prosthetic heart valve A bileaflet heart valve incorporates a pivot arrangement that minimizes resistance to downstream blood flow in the open position yet has prompt response and therefore minimal regurgitation upon flow reversal. A valve body having an axially curved entrance... | 06/24/1997 |
| 5545216 | Prosthetic heart valve A bileaflet heart valve is shown which incorporates a pivot arrangement that minimizes resistance to downstream blood flow in the open position yet has prompt response and therefore minimal regurgitation upon flow reversal. The valve employs a pair of ide... | 08/13/1996 |
| 5522886 | Heart valve prostheses Check valves for fluid flow, particularly for use as replacement heart valves, employ annular valve bodies with hinge arrangements which support one or more occluders for movement between open and closed orientations. Illustrated are single occluder and t... | 06/04/1996 |
| 5326372 | Prosthetic heart valve assembly A prosthetic heart valve assembly of the type having a ring member and pivotable leaflet structure is provided. Each individual leaflet pivots on a pair of peripheral flat ear members that oscillate in mating respective spherical bearing recesses. These r... | 07/05/1994 |
| 5026391 | Curved butterfly bileaflet prosthetic cardiac valve An annular valve body having a central passageway for the flow of blood therethrough with two curved leaflets each of which is pivotally supported on an accentric positioned axis in the central passageway for moving between a closed position and an open p... | 06/25/1991 |
| 4689046 | Heart valve prosthesis A heart valve prosthesis with an annular body portion and at least one valve leaflet moveable between open, closed, and intermediate positions. The body includes leaflet ear support formations, each with a contoured recess having spaced apart, tapered arc... | 08/25/1987 |
| 4276658 | Heart valve prosthesis A heart valve prosthesis coated in its entirety with pyrolytic carbon. In a preferred embodiment, the prosthesis is formed of a base having a blood passageway and dual leaflets pivotally secured to the base to regulate the flow of blood through the passag... | 07/07/1981 |
