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| Number | Title | Issue Date |
| 8092522 | Artificial valve prostheses with a free leaflet portion An implantable valve prosthesis including a frame defining a lumen extending between a proximal frame end and a distal frame end and a leaflet positioned within the lumen and having a distal edge attached to the frame and a proximal edge free of the frame. The leafl... | 01/10/2012 |
| RE42857 | Method of laser cutting pericardial tissue for use with an implantable medical device A method of cutting material for use in an implantable medical device employs a plotted laser cutting system. The laser cutting system is computer controlled and includes a laser combined with a motion system. The laser precisely cuts segments out of source material... | 10/18/2011 |
| 7972376 | Capping bioprosthetic tissue to reduce calcification A treatment for bioprosthetic tissue used in implants or for assembled bioprosthetic heart valves to reduce in vivo calcification. The method includes applying a calcification mitigant such as a capping agent or an antioxidant to the tissue to specifically inhibit o... | 07/05/2011 |
| 7563280 | Efficient implantation of heart valve prostheses Tools can be used to assist with the implantation of heart valve prostheses, especially stentless aortic heart valve prostheses. In some embodiments, a heart valve prosthesis includes a plurality of flexible leaflets, a commissure support and a plurality of fastener... | 07/21/2009 |
| 7338484 | Aortic heart valve prosthesis sizer and marker Improved sizers and markers include a cylindrical section and a handle extending from the cylindrical section. The cylindrical section has a diameter approximately equal to the diameter of an aortic heart valve prosthesis. The cylindrical section can include a marki... | 03/04/2008 |
| 7323010 | Biomaterial including animal corneal tissue Biomaterial including tissues basically obtained from an animal cornea, in particular, from a fish cornea. A cardiac valve (10) which may envisage at least one cusp (15) made with an organic tissue obtained from this particular biomaterial. ... | 01/29/2008 |
| 7316712 | Tissue heart valve with annulus support structure A heart valve prosthesis can be formed with a harvested tissue heart valve and a sewing rim that extends outwardly from the annulus of the harvested heart valve for easier attachment of the prosthesis. The heart valve prosthesis can further include a belt that exten... | 01/08/2008 |
| 7311730 | Support apparatus and heart valve prosthesis for sutureless implantation An apparatus is disclosed for supporting a heart valve at an annulus of an implantation site. The apparatus includes a base portion operative to maintain a circumferential dimension thereof. A plurality of fingers extend axially and radially outwardly from the first... | 12/25/2007 |
| 7290494 | Method for manufacturing stent-grafts A sewing machine is provided which is capable of sewing reinforcing wire to tubular grafts in order to form stent grafts. A bobbin (which may be seated in a shuttle) carries a bottom thread through the bore of the tubular graft and forms a stitch in combination with... | 11/06/2007 |
| 7267686 | Implantable prosthetic valve A prosthetic valve for implantation within a fluid conducting lumen within a body includes an elongate generally cylindrical radially collapsible valve body scaffold defining a fluid passageway therethrough for retentive positioning within the lumen. A radially coll... | 09/11/2007 |
| 7261732 | Stent mounted valve There is described a prosthetic valve to be inserted into a body lumen, the valve having leaflets that are spread apart during forward flow of fluid to create an orifice, and the leaflets coming into contact with each other during reverse flow of fluid, thereby impe... | 08/28/2007 |
| 7254988 | Method and apparatus for testing pulsatile endurance of a vascular implant A method for testing the pulsatile endurance of a vascular implant 3 comprises placing a resilient insert 4 into the implant and repeatedly expanding and contracting the insert, thereby expanding and contracting the implant. The insert preferably has a... | 08/14/2007 |
| 7252681 | Heart valve structures A replacement heart valve structure including a structure of tissue which is an intact, mammalian heart valve that has been harvested and treated to preserve it. A conventional fabric sleeve is typically disposed concentrically around the outside of the tissue struc... | 08/07/2007 |
| 7247167 | Low profile heart valve prosthesis A heart valve prosthesis includes a valve member having an inflow end, an outflow end, and a generally cylindrical sidewall portion extending between the inflow end and the outflow end. The valve member includes at least one leaflet moveable relative to the sidewall... | 07/24/2007 |
| 7244242 | Valve treatment catheter and methods The invention provides a catheter for insertion into a biological passage which contains a first flowing fluid, the catheter including a tubular member having a proximal end and a distal end; a fluid delivery lumen contained within the tubular member; an inflatable ... | 07/17/2007 |
| 7217284 | Apparatus and methods for treating tissue Apparatus and methods are provided for thermally and/or mechanically treating tissue, such as valvular structures, to reconfigure or shrink the tissue in a controlled manner. The apparatus comprises a catheter in communication with an end effector which induces a te... | 05/15/2007 |
| 7201772 | Fluid flow prosthetic device A prosthetic device including a valve-orifice attachment member attachable to a valve in a blood vessel and including a fluid inlet, and a diverging member that extends from the fluid inlet, the diverging member including a proximal end near the fluid inlet and a di... | 04/10/2007 |
| 7162850 | Method of packaging a bone allograft intended for a spinal fusion procedure A system and method of packaging a bone allograft for use in a future medical procedure in which the bone allograft is stored in a saturated saline solution in an airtight container. The saline solution keeps the allograft hydrated and may be saturated with a combin... | 01/16/2007 |
| 7160320 | Reed valve for implantation into mammalian blood vessels and heart with optional temporary or permanent support A multi-leaflet valve adapted to serve as a prosthesis for diseased native valve of a mammal is constructed of biologic membrane or of biocompatible synthetic membrane. The valve has the shape of a truncated cone that has an inflow and an outflow orifice with leafle... | 01/09/2007 |
| 7156872 | Implantable valve system An implantable valve having a valve element or leaflet and a base that is attachable to a vessel wall using a connector such as a screw, pin or a staple. The valve can be implanted using a catheter to position the valve in a desired location and drive the connector ... | 01/02/2007 |
| 7141064 | Compressed tissue for heart valve leaflets A process and system for compressing bioprosthetic tissue for use in medical implants. The process involves placing the tissue between two compressive surfaces and applying a force to reduce any nonuniformity of thickness in the tissue, while at the same time reduce... | 11/28/2006 |
| 7137947 | Endovascular prosthesis having a layer of biological tissue An apparatus (10) for grafting of a blood vessel (12) and a method of forming the apparatus (10) is provided. The apparatus (10) comprises an expandable support member (16) having inner and outer surfaces (36 and 34).... | 11/21/2006 |
| 7101396 | Minimally invasive valve replacement system Methods and systems for minimally invasive replacement of a valve. The system includes a collapsible valve and anchoring structure, devices and methods for expanding the valve anchoring structure, adhesive means to seal the valve to the surrounding tissue, a cathete... | 09/05/2006 |
| 7087079 | Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve A stentless bioprosthetic valve includes at least one piece of biocompatible material comprising a bi-leaflet conduit. The conduit has a distal end and a proximal end that defines a first annulus for suturing to the valve annulus of a heart. The conduit further incl... | 08/08/2006 |
| 7081131 | Artificial valve Method and apparatus implementing and using techniques for controlling flow in a body lumen, including use of an implantable medical device. The device includes a membrane implantable in a body lumen and invertibly deformable between a first position and a second po... | 07/25/2006 |
| 7037333 | Prosthetic heart valve A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then s... | 05/02/2006 |
| 7029434 | Methods for treating implantable biological tissues to mitigate post—implantation calcification A method for treating fixed biological tissue inhibits calcification of the biological tissue following implantation thereof in a mammalian body. The method includes placing the biological tissue in contact with glutaraldehyde and then heating the glutaraldehyde. Al... | 04/18/2006 |
| 7025780 | Valvular prosthesis A valvular prosthesis and method of using the prosthesis are disclosed. A valve apparatus is located within a stent apparatus, such that the prosthesis is deformable between a first condition and a second condition, in which the prosthesis has a reduced cross-sectio... | 04/11/2006 |
| 7014655 | Method for conserving biological prostheses, conserved biological prostheses and conserving solutions The invention concerns a method of conserving biological prostheses, wherein the method includes the following steps: (a) treating biological prostheses with a solution which contains a mixture of epoxide compounds which are at least in part of different lengths; (b... | 03/21/2006 |
| 7007698 | Body lumen closure Method and apparatus implementing and using techniques for body lumen closure, including use of an implantable medical closure device. The device includes a flexible strand defining an arcuate form. The strand is deformable upon implantation from a large cross-secti... | 03/07/2006 |
| 6997950 | Valve repair device A valve repair device and method of repair for the mitral valve of the heart is disclosed. The valve repair device includes a leaflet portion, a muscle portion, and a plurality of chords connecting the leaflet portion to the muscle portion. The valve repair device i... | 02/14/2006 |
| 6945957 | Valve treatment catheter and methods The invention provides a catheter for insertion into a biological passage which contains a first flowing fluid, the catheter including a tubular member having a proximal end and a distal end; a fluid delivery lumen contained within the tubular member; an inflatable ... | 09/20/2005 |
| 6945996 | Replacement mitral valve A sewing ring (12) has a diameter commensurate with a diameter of a removed mitral valve. Skirts (44, 46) of mesh or net material extend downward from the sewing ring and line the walls of an associated vessel (58). Basal chordae simulating stru... | 09/20/2005 |
| 6916338 | Synthetic leaflets for heart valve repair or replacement Heart valve leaflets (10) are described that include a plurality of supports (350) within a coapting portion (20) and a substantially arcuate portion (30). The plurality of supports (350) provide the leaflet (10) with anisot... | 07/12/2005 |
| 6911043 | Prosthetic heart value A tubular prosthetic semilunar or atrioventricular heart valve is formed by cutting flat, flexible leaflets according to a pattern. The valve is constructed by aligning the side edges of adjacent leaflets so that the leaflet inner faces engage each other, and then s... | 06/28/2005 |
| 6872226 | Method of cutting material for use in implantable medical device A method of cutting material for use in an implantable medical device employs a plotted laser cutting system. The laser cutting system is computer controlled and includes a laser combined with a motion system. The laser precisely cuts segments out of source material... | 03/29/2005 |
| 6861211 | Stabilization of implantable bioprosthetic devices The invention relates to methods of stabilizing glycosaminoglycans in a biological tissue (e.g. a bioprosthetic implant) in conjunction with cross-linking of protein in the tissue. The methods of the invention improve the mechanical integrity of the device and impro... | 03/01/2005 |
| 6837902 | Methods of making bioprosthetic heart valves with strain matched leaflets Heart valve leaflet selection methods and apparatuses which subject individual leaflets to loads and measure the resulting deflection to more reliably group leaflets of similar physical characteristics for later assembly in prosthetic heart valves. The deflection te... | 01/04/2005 |
| 6830586 | Stentless atrioventricular heart valve fabricated from a singular flat membrane A stentless atrioventricular valve intended for attaching to a circumferential valve ring and papillary muscles of a patient comprising a singular flexible membrane of tissue or synthetic biomaterial, the valve having a sewing ring, an anterior cusp and a posterior ... | 12/14/2004 |
| 6719789 | Replacement heart valve A prosthetic heart valve has leaflets made of a thin and flexible material. The side edges of adjacent leaflets are sewn together so as to form a substantially tubular valve structure having an in-flow end and an out-flow end. Each of the leaflets is adapted to flex... | 04/13/2004 |
