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| Number | Title | Issue Date |
| 5413597 | Three-layer vascular prostheses The invention relates to three-layer vascular prostheses comprising an internal layer 1, a middle layer 2 and an external layer 3 which is characterized in that the middle layer 2 is made from a physiologically non-resorbable, porous material, and the int... | 05/09/1995 |
| 5411550 | Implantable prosthetic device for the delivery of a bioactive material An implantable prosthetic device for sustained release of a bioactive material into a fluid flow pathway of a patient comprises a body adapted for attachment to the fluid flow pathway. The body defines a primary lumen for accommodating fluid flow therethr... | 05/02/1995 |
| 5405378 | Device with a prosthesis implantable in the body of a patient The device comprises a prosthesis designed as a hollow body compressed against the action of restoring spring forces to a cross section reduced relative to an expanded use position, and held in this position by a strippable sheath. After the sheath is str... | 04/11/1995 |
| 5399352 | Device for local drug delivery and methods for using the same A device for the local delivery of a substance into a natural tissue conduit in the mammalian body, having a first clement capable of contacting the lumen of the conduit and a second element which overlays first element, a reservoir being formed between t... | 03/21/1995 |
| 5376376 | Resorbable vascular wound dressings The present invention is related to prostheses, their methods of manufacture and methods for repairing vascular lesions using such prostheses. Natural polymers such as collagen are processed and fabricated to form tubular resorbable vascular wound dressin... | 12/27/1994 |
| 5370681 | Polyumenal implantable organ A polylumenal implantable device comprises a body defining a plurality of capillary lumina. The prosthetic device is suitable for implantation in a patient as an arterial or venous bypass graft or shunt, or intra-organ implant as well as other purposes. T... | 12/06/1994 |
| 5356433 | Biocompatible metal surfaces Metallic surfaces of medical devices or components of medical devices are provided that have enhanced biocompatibility properties. The surfaces are prepared by a two-step procedure including covalently linking an organosilane having amine reactive sites w... | 10/18/1994 |
| 5314688 | Local delivery of dipyridamole for the treatment of proliferative diseases A method of inhibiting cell proliferation in mammals which comprises the local delivery of an inhibitory amount of dipyridamole. Inhibiting cell proliferation is useful for the treatment of proliferative diseases such as vascular restonesis, scleroderma, ... | 05/24/1994 |
| 5207705 | Prosthesis of foam polyurethane and collagen and uses thereof An implantable medical prosthesis is provided having a uniform mixture of foam polyurethane and collagen. The prosthesis can be shaped into an elongated hollow body tube useful for implantation in an animal. Alternatively, the prosthesis can be shaped int... | 05/04/1993 |
| 5197977 | Drug delivery collagen-impregnated synthetic vascular graft A collagen impregnated vascular graft including drug materials complexed with the collagen to be released slowly from the graft following implant. The graft is a porous synthetic vascular graft substrate having collagen fixed to the graft substrate and cr... | 03/30/1993 |
| 5163952 | Expandable polymeric stent with memory and delivery apparatus and method Self-restrained stent for use in a lumen of a vessel of a patient having a body with the vessel therein, comprising a substantially cylindrical member formed of a plastic material having a built-in elastic predetermined diameter and having a memory provid... | 11/17/1992 |
| 5123917 | Expandable intraluminal vascular graft An expandable intraluminal vascular graft includes a flexible cylindrical inner tube having a outer periphery and a plurality of separate scaffold member mounted on the outer periphery of the inner tube. The scaffold members are expandable, ring-like and ... | 06/23/1992 |
| 5024671 | Microporous vascular graft A vascular graft at least partially formed from porous hollow fibers, with at least some of the porous hollow fibers being located adjacent an inner surface of the vascular graft. The vascular grafts of the invention have a relatively small pore size for ... | 06/18/1991 |
| 4784659 | Vessel and prosthesis impregnated with diisocyanate crosslinked gelatin The invention relates to vessel prostheses formed from a porous vascular prosthesis impregnated with diisocyanate crosslinked gelatin for sealing the pores.... | 11/15/1988 |
| 4753652 | Biomaterial implants which resist calcification A biomaterial implant into which is incorporated a sustained release polymer containing an anticalcium agent.... | 06/28/1988 |
| 4749585 | Antibiotic bonded prosthesis and process for producing same There is disclosed an improved prosthesis coated, respectively, with an ionic surfactant, an antibiotic and/or antithrombiotic agent and treated with an immobilizing ionic exchange compound, to remove un-antibiotic bound ionic surfactant. The drug may be ... | 06/07/1988 |
| 4740382 | Antibiotic bonded prosthesis and process for producing same There is disclosed an improved prosthesis coated, respectively, with a cationic surfactant, an antibiotic compound and treated with an cationic exchange compound, to remove un-antibiotic bound cationic surfactant.... | 04/26/1988 |
| 4619655 | Plaster of Paris as a bioresorbable scaffold in implants for bone repair Plaster of Paris is employed to form implants as well as a bioresorbable scaffold for implants and bone repair in animals. In bone repair, the plaster is mixed with a non-bioresorbable calcium source, such as calcium phosphate ceramic, to stimulate bone f... | 10/28/1986 |
| 4612337 | Method for preparing infection-resistant materials An infection-resistant polymeric material, such as polytetrafluoroethylene, for use on or within a human or animal body, for example, in the form of a vascular graft, can be prepared by an improved method which comprises the following sequence of steps: (... | 09/16/1986 |
| 4563485 | Injection-resistant materials and method of making same through use of nalidixic acid derivatives Infection-resistant materials, and methods of preparing same, suitable for use within the interior of a human or animal body in such forms as vascular grafts prostheses, or other implanted devices. The material is rendered infection-resistant by incorpora... | 01/07/1986 |
| 4553974 | Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor A process for the treatment of collagenous tissue to adapt it for use in a prosthetic implant and to promote the growth of endothelial cells thereon after implantation comprising treatment with at least one surfactant prior to fixation, treatment with age... | 11/19/1985 |
| 4485097 | Bone-equivalent and method for preparation thereof A bone-equivalent, useful in the fabrication of prostheses, is disclosed which is prepared from a hydrated collagen lattice contracted by fibroblast cells and containing demineralized bone powder.... | 11/27/1984 |
| 4451568 | Composition for binding bioactive substances An acrylic-acid- based photopolymerizable composition is prepared which is capable of binding bioactive substances after being photopolymerized. The composition may be applied as a coating on a carrier substrate, photopolymerized and a bioactive substance... | 05/29/1984 |
| 4347234 | Medicinally useful, shaped mass of collagen resorbable in the body A shaped mass resorbable in the body, comprises collagen and a bioresorbable binding agent for collagen, the binding agent being selected, e.g., from polymers of C2-16 -hydroxyalkanoic acids, polymers of natural amino acids, hydrolyzed c... | 08/31/1982 |
| 4044404 | Fibrillar lining for prosthetic device A lining for a prosthetic device such as an artificial internal organ comprises a mat of fibres prepared by electrostatically spinning an organic material and collecting the spun fibres on a receiver.... | 08/30/1977 |
