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| Number | Title | Issue Date |
| 8187321 | Expandable medical device for delivery of beneficial agent An expandable medical device has a plurality of elongated struts joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter. At least one of the plurality of struts in... | 05/29/2012 |
| 8187322 | Drug eluting stent and method of making the same A drug eluting stent comprising a multilayer tubular structure which includes at least one intermediate layer having reservoirs therein for deposition of a drug, the intermediate layer eluting drug in a lateral direction, and methods of making the same. ... | 05/29/2012 |
| 8187320 | Medical implants containing FK506 (tacrolimus) Implants and methods of making same are provided for treatment or prophylaxis of coronary or peripheral vascular constrictions or vascular occlusions, and particularly, stenoses or restenoses, that comprise FK506 in chemically covalently bound, non-covalently bound ... | 05/29/2012 |
| 8137397 | Medical devices Medical devices, particularly stents, suitable for drug delivery and including a sugar, sugar derivative, inorganic ionic salt, polysaccharide, amino acid, amino acid derivative, polypeptide, surfactant, or combination thereof, are disclosed. ... | 03/20/2012 |
| 8128689 | Bioerodible endoprosthesis with biostable inorganic layers Medical devices such as endoprostheses (e.g., stents) containing one or more biostable layers (e.g., biostable inorganic layers) and a biodegradable underlying structure are disclosed. ... | 03/06/2012 |
| 8128687 | Drug-eluting stent with filament strands An intravascular stent having a prefabricated, patterned polymeric sleeve for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel is disclosed. The polymeric sleeve is attached to at least a p... | 03/06/2012 |
| 8128688 | Carbon coating on an implantable device A carbon coating on a stent having a bioactive agent covalently attached thereto and methods of making the same are described. The covalent attachment may be achieved via a photo-reactive chemical or a thermo-reactive chemical. In some embodiments, the carbon coatin... | 03/06/2012 |
| 8128690 | Endoluminal device for in vivo delivery of bioactive agents The present invention consists of an implantable structural element for in vivo delivery of bioactive active agents to a situs in a body. The implantable structural element may be configured as an implantable prosthesis, such as an endoluminal stent, cardiac valve, ... | 03/06/2012 |
| 8123798 | Biofilm formation inhibitor and treatment device thereof A treatment device such as a biliary stent, capable of effectively and continuously inhibiting biofilm formation, and a biofilm formation inhibitor suitable for coating on the treatment device by killing all bacteria including E. coli and by suppressing the g... | 02/28/2012 |
| 8118864 | Drug delivery endovascular graft An endovascular graft of the present invention embodies a graft system utilizing the textile fabric of the prosthesis for drug storage and delivery. These drug-eluting devices involve treating the textile fabric with therapeutic agents to provide a method of deliver... | 02/21/2012 |
| 8114152 | Stent coating An expandable stent for use within a body passageway having a body member with two ends and a wall surface disposed between the ends. The body member has a first diameter to permit delivery of the body member into a body passageway and a second expanded diameter. Th... | 02/14/2012 |
| 8114151 | Stent with tabs and holes for drug delivery A stent can include a tubular body, a plurality of circumferential serpentine bands, a plurality of connectors extending between immediately adjacent serpentine bands, and a plurality of tabs. The plurality of tabs include peak tabs and trough tabs. Each peak tab an... | 02/14/2012 |
| 8100963 | Biodegradable device A device that is at least partially formed of a biodegradable polymer. The device can be at least partially formed by MEMS technology. The device can include one or more micro-structures that are also formed by MEMS technology. The device can include one or more age... | 01/24/2012 |
| 8070797 | Medical device with a porous surface for delivery of a therapeutic agent The present invention is generally directed to implantable medical devices for delivering therapeutic agents to the body tissue of a patient and methods for making such medical devices. In particular, the present invention is directed to implantable medical devices,... | 12/06/2011 |
| 8070796 | Thrombosis inhibiting graft A medical method that is adapted for introducing the medical device into the vascular system of a body which is designed to inhibit or prevent thrombosis after the insertion of the medical device. ... | 12/06/2011 |
| 8066762 | Assembly for manufacturing an implantable polymeric medical device A polymeric tube is positioned on a polymeric mandrel and then laser cut to form an implantable medical device, such as a stent. The method reduces contamination of the inner surface of the stent, which would be caused if conventional glass or metal mandrels are use... | 11/29/2011 |
| 8062352 | Implantable device The invention relates to an implantable device for local release of at least one drug at a predefined location in a natural cavity having a wall in the body of a mammal, characterized by at least one drug reservoir, which can be affixed in the cavity, the drug reser... | 11/22/2011 |
| 8052745 | Endoprosthesis In embodiments a stent includes a stent body and a wire-form carrying a drug located along the stent body. ... | 11/08/2011 |
| 8048149 | Intraluminal stent including therapeutic agent delivery pads, and method of manufacturing the same An intraluminal stent, an intraluminal stent delivery system, and a method of manufacturing an intraluminal stent. The stent comprises a body and at least one pad operably attached to the stent body. The pad includes at least one therapeutic agent disposed thereon. ... | 11/01/2011 |
| 8048150 | Endoprosthesis having a fiber meshwork disposed thereon The present invention comprises a medical device having an underlying structure on which is disposed a fiber meshwork composed of one or more fibers of substantially uniform diameter. The fiber meshwork may optionally have a multi-layer structure disposed upon it. E... | 11/01/2011 |
| 8043367 | Stents formed from polymer-bioceramic composite with radiopaque bioceramic particles Implantable medical devices fabricated at least in part of a polymer-bioceramic composite having bioceramic particles with radiopaque functional groups grafted to a surface of the bioceramic particles are disclosed. Implantable medical devices fabricated at least in... | 10/25/2011 |
| 8038709 | Local delivery of therapeutic agent to heart valves The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and c... | 10/18/2011 |
| 8029561 | Drug combination useful for prevention of restenosis The current invention comprises an approach to solving the clinical problem of restenosis, which involves the administration of combinations of drugs to patients undergoing PTCA or stent implantation. In one embodiment of the invention, an antiproliferative agent su... | 10/04/2011 |
| 8016880 | Stent having spiral channel for drug delivery A drug delivery stent is formed by a metallic or polymeric tubular strut which is shaped into a generally cylindrical configuration, the tubular strut having a central lumen for containing a therapeutic substance or drug therein. The tubular strut has a continuous c... | 09/13/2011 |
| 8012200 | Endovascular magnetic method for targeted drug delivery The method for endovascular magnetic targeting drug delivery in a vascular wall and adjoining tissues, wherein an endovascular mesh stent with paramagnetic properties is preliminary implanted in the area of interest by a catheter, a polymeric magneto-responsive carr... | 09/06/2011 |
| 7998195 | Device with engineered surface architecture coating for controlled drug release In one embodiment of the present invention a coating topology, or engineered surface architecture that may be referred to as a microdroplet deposited engineered surface architecture is provided. A plurality of drops are placed on the stent with the purpose, of build... | 08/16/2011 |
| 7967856 | Microtubes for therapeutic delivery A medical implant that delivers therapeutic via microtubes and a method of making the same is provided. In one embodiment a biologically implantable structure adapted to fit within the body of a patient is provided. This structure may have a plurality of individual ... | 06/28/2011 |
| 7967855 | Coated medical device A stent that is adapted for introduction into a body passageway and which releases at least one biological agent after being inserted in the body passageway. The release of the at least one biological agent can be a controlled release via molecular diffusion through... | 06/28/2011 |
| 7955382 | Endoprosthesis with adjustable surface features Endoprostheses (e.g., stents) containing adjustable surfaces are disclosed. ... | 06/07/2011 |
| 7951193 | Drug-eluting stent A stent for delivering therapeutic agents to a body lumen includes a plurality of circumferential serpentine bands with each band comprising a plurality of struts. At least one strut has at least one first well region and at least one second well region. The at leas... | 05/31/2011 |
| 7935143 | Stent formed from polymer-bioceramic composite with radiopaque bioceramic particles Implantable medical devices fabricated at least in part of a polymer-bioceramic composite having bioceramic particles with radiopaque functional groups grafted to a surface of the bioceramic particles are disclosed. Implantable medical devices fabricated at least in... | 05/03/2011 |
| 7931683 | Articles having ceramic coated surfaces According to an aspect of the invention, articles are provided which comprise a substrate and a ceramic coating which covers at least a portion of the substrate surface. The ceramic coating includes raised ceramic shells connected by a ceramic layer that is conforma... | 04/26/2011 |
| 7922760 | In situ trapping and delivery of agent by a stent having trans-strut depots A method of delivering an agent into a bodily lumen, the method comprising: implanting an implantable medical device into a treatment site of a lumen, the device having an abluminal face and a luminal face, wherein the device includes depots that extend from an open... | 04/12/2011 |
| 7914573 | Polymeric stent having modified molecular structures A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. ... | 03/29/2011 |
| 7909865 | Expandable medical device for delivery of beneficial agent An expandable medical device having a plurality of elongated struts, the plurality of elongated struts being joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter... | 03/22/2011 |
| 7909864 | Implantable medical devices having adjustable pore volume and methods for making the same The present invention is directed to implantable medical devices which may be used for controllably releasing a therapeutic agent within a patient and methods for making the same. These medical devices may include porous coatings, which may be polymer-free, located ... | 03/22/2011 |
| 7901451 | Drug-delivery endovascular stent and method for treating restenosis A radially expandable, endovascular stent designed for placement at a site of vascular injury, for inhibiting restenosis at the site, a method of using, and a method of making the stent. The stent includes a radially expandable body formed of one or more metallic fi... | 03/08/2011 |
| 7901453 | Coated implantable medical device A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract, and at least one layer 18 of an immunosuppressive agent posited over at... | 03/08/2011 |
| 7901452 | Method to fabricate a stent having selected morphology to reduce restenosis Methods of fabricating a stent and a stent having selected morphology on abluminal and luminal surfaces of the stent are disclosed. ... | 03/08/2011 |
| 7896914 | Coated implantable medical device A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; ... | 03/01/2011 |
