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| Number | Title | Issue Date |
| 8109923 | Osmotic pump with remotely controlled osmotic pressure generation Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in ord... | 02/07/2012 |
| 7976535 | Method for control of the volume flux of a liquid in an osmotic micropump and osmotic micropump The invention refers to a method for control of a volume flow in an osmotic micropump and an osmotic micropump. According to the invention, the osmotically driven volume flow of the solvent through the sempipermeable diaphragm of an osmotic micropump is controlled b... | 07/12/2011 |
| 7896868 | Method and system for control of osmotic pump device Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in ord... | 03/01/2011 |
| 7896867 | Fluid delivery device having an electrochemical pump with an ion-exchange membrane and associated method The present invention is directed to an apparatus and method for controllably adjusting a fluid delivery device. The device includes an electrochemical pump capable of transporting a fluid. A displaceable member is positioned between a pump product chamber and a res... | 03/01/2011 |
| 7879027 | Controlled release devices for fusion of osteal structures A device includes a first reservoir configured to include a degradation agent, a first control element configured to provide access to the first reservoir, and an expandable component configured to extend to engage an osteal structure. ... | 02/01/2011 |
| 7879028 | Osmotic delivery systems and piston assemblies for use therein An osmotic delivery system is disclosed for delivering an active agent formulation to a fluid environment. The osmotic delivery system typically comprises a reservoir having a lumen that contains the active agent formulation and an osmotic agent formulation and a pi... | 02/01/2011 |
| 7771414 | Controlled release devices for therapeutic treatments of spinal discs A device includes a first reservoir configured to include a degrading agent, a first valve in fluid communication with the first reservoir, and a reservoir driver configured to manipulate the first reservoir to effect a first reservoir condition based on a first tis... | 08/10/2010 |
| 7699834 | Method and system for control of osmotic pump device Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in ord... | 04/20/2010 |
| 7682356 | Osmotic delivery systems and piston assemblies for use therein An osmotic delivery system is disclosed for delivering an active agent formulation to a fluid environment. The osmotic delivery system typically comprises a reservoir having a lumen that contains the active agent formulation and an osmotic agent formulation and a pi... | 03/23/2010 |
| 7621907 | Implantable drug delivery system An implantable medicament delivery device includes a core body which further includes a single basin or multiple smaller basins for containing a drug or a medicament. Each basin is covered by a screen. The implantable drug delivery device is placed within the body o... | 11/24/2009 |
| 7479135 | Automatic conveyor driven by hydrogels, provided with an adjustable output characteristic for conveying a medium A device for the dosed output of a substance, the device involving hydrogel-based osmotic drive, wherein output characteristics of the device, including a time profile, may be adjusted by a user. In some embodiments, the device may be used once and, in other embodim... | 01/20/2009 |
| 7470267 | Fluid delivery device having an electrochemical pump with an anionic exchange membrane and associated method A fluid delivery device, comprising an electrochemical pump, wherein the pump is capable of transporting water; a pump product chamber, wherein the pump product chamber is capable of retaining water generated from the pump; a displaceable member positioned between t... | 12/30/2008 |
| 7458965 | Fluid delivery device having an electrochemical pump with an ion-exchange membrane and associated method The present invention is directed to an apparatus and method for controllably adjusting a fluid delivery device. The device includes an electrochemical pump capable of transporting a fluid. A displaceable member is positioned between a pump product chamber and a res... | 12/02/2008 |
| 7419484 | Administering device with an osmotic drive An administering device with an osmotic drive for administering an injectable product includes a housing with a first chamber containing a solvent, a second chamber containing a solution and a product chamber for accommodating the product. A semi-permeable membrane ... | 09/02/2008 |
| 7407500 | Osmotic delivery system flow modulator apparatus and method An osmotic delivery system flow modulator assembly, an osmotic delivery system with a flow modulator assembly, and a method of assembling an osmotic delivery system. The osmotic delivery system flow modular assembly includes a body having a hole located through the ... | 08/05/2008 |
| 7407499 | Osmotic pump with self-retaining, fast-start membrane plug An osmotic pump includes a capsule having at least one delivery port formed at a first end and a membrane plug retained in a second end of the capsule remote from the delivery port to provide a fluid-permeable barrier between an interior and an exterior of the capsu... | 08/05/2008 |
| 7384418 | Methods and devices for delivery of agents to breast milk ducts The invention provides devices, kits and methods for delivering an agent to a breast milk duct. Intraductal agent delivery provides an opportunity to treat a breast condition locally and avoid the pitfalls of systemic drug delivery for a local condition. Time-releas... | 06/10/2008 |
| 7371229 | Dual electrode advanced electrochemical delivery system The present invention is disclosed herein as an electrochemical cell having a cell housing with a first half cell and a second half cell, and an ion selective membrane between the cells. The electrochemical cell further has a first electrode positioned within the fi... | 05/13/2008 |
| 7371228 | Delivery of therapeutics to treat aneurysms A method and device for the treatment of an aneurysm are provided. Different therapeutic agents are delivered to the aneurysmal site by a reservoir and delivery means in a localized, and, in some embodiments, time-released regimen, to treat, limit and reduce the sev... | 05/13/2008 |
| 7364729 | Method of inducing a CTL response Disclosed herein are methods for inducing an immunological CTL response to an antigen by sustained, regular delivery of the antigen to a mammal so that the antigen reaches the lymphatic system. Antigen is delivered at a level sufficient to induce an immunologic CTL ... | 04/29/2008 |
| 7350479 | System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp An “implant and forget” device for interacting with biota after a pre-established time period. Preferably, the biota are fauna and more particularly fish. In select embodiments, the device comprises packaging enclosing apparatus for timing interaction via openin... | 04/01/2008 |
| 7347854 | Method and apparatus for automatically modifying delivery profile of drug delivery system The present invention relates to an implantable drug delivery device which includes a fluid drug reservoir, a catheter, a controllable fluid transfer device, e.g., a pump or valve, and a drug delivery control means. The control means in accordance with the invention... | 03/25/2008 |
| 7338464 | Non-constant pressure infusion pump The present invention relates to an implantable infusion pump having a refillable infusate reservoir in fluid communication with a delivery site via a flow path. This flow path includes a flow resistance. The infusion pump includes a sensing device(s), positioned re... | 03/04/2008 |
| 7338664 | Color changing matrix as wear indicator A sustained-release matrix for dental application includes either an anti-microbial agent or a colorant that is released from the matrix when the matrix contacts water. The preferred matrices include a water-soluble polymer and a water-insoluble support resin. ... | 03/04/2008 |
| 7338663 | Expandable osmotic composition and coating suspension The present invention includes an expandable osmotic layer and a coating suspension for providing an expandable osmotic layer, both of which are useful for the manufacture of controlled release dosage forms. The expandable osmotic layer of the present invention may ... | 03/04/2008 |
| 7337993 | Electrostatic atomisation device An atomization device comprises a conduit containing liquid to be atomized, a spray electrode (1) and a discharge electrode (3). Each electrode is adjacent to a dielectric (5) and they are connected in an electrical circuit (10) to enable... | 03/04/2008 |
| 7335193 | Osmotically-driven fluid dispenser Improvements in a mini-osmotic pump and coating compositions are described. The dispensing pump includes an inner fluid-filled bag encased by an osmotic layer and outer, semi-permeable membrane. The inner bag is formed with an arcuate edge at the open end of the bag... | 02/26/2008 |
| 7316680 | Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel An implantable osmotically driven delivery system having a dynamic, two-way valve and a self-adjusting, variable geometry fluid flow channel. As pressure within the agent delivery system increases, the fluid channel narrows, thereby restricting flow. At exceptionall... | 01/08/2008 |
| 7316816 | Temperature and pH sensitive copolymers The invention is directed to a copolymer comprising at least three types of monomeric units, said three types of monomeric units comprising: a temperature-sensitive unit, a hydrophilic unit, and a ... | 01/08/2008 |
| 7303674 | Forward osmosis pressurized device and process for generating potable water There is disclosed a process and device for Forward Osmosis (FO) Pressurized Device (FOPD) in general and one hydraulically coupled to a reverse osmosis (RO device for a FOPRO (Forward Osmosis Pressurized Reverse Osmosis). Specifically, there is disclosed a passive ... | 12/04/2007 |
| 7287485 | Temperature activated systems A shape memory material activated device of the present invention uses a shape memory material activator to create a path through a shell wall of the device. The path through the shell wall may release a substance contained in the shell or allow a substance to enter... | 10/30/2007 |
| 7275420 | Fluid sensor fixture for dynamic fluid testing A system that facilitates measurement, analysis, and automatic maintenance of fluid comprises a fluid, and a casing that includes a plurality of apertures is immersed in the fluid. The apertures are opened to permit the fluid to enter the casing and closed to confin... | 10/02/2007 |
| 7276634 | Reduction of the viscosity of reactive heavy byproducts during the production of 1,3-propanediol The present invention is an improvement upon the process for the production of 1,3-propanediol wherein an aqueous solution of 3-hydroxy propanal is formed, catalyst, if any, used in said formation is removed from the solution, sodium hydroxide is added to the soluti... | 10/02/2007 |
| 7250043 | Catheter for modification of agent formulation The present invention provides a catheter for use in delivering formulation that allows modification of the formulation prior to or concomitant with its transport or at a delivery site. The catheter comprises an elongate body, which defines an inner lumen extending ... | 07/31/2007 |
| 7241457 | Osmotically driven active agent delivery device providing an ascending release profile In one aspect, the present invention is directed to an osmotic pump that automatically provides an ascending release rate of active agent as the osmotic pump functions in an environment of operation and may be designed for implantation within a desired animal or hum... | 07/10/2007 |
| 7235068 | Osmotic delivery system having space-efficient piston An osmotic delivery system having a space-efficient piston is provided. The enclosure has an interior holding the piston, a protein or peptide, and an osmotic agent. The piston is movable with respect to an interior surface of the capsule, and defines a movable seal... | 06/26/2007 |
| 7211076 | Medical device for fluid delivery having low fluid flow rate A device for delivering a drug includes a body having a proximal end and a distal end and an opening in the distal end thereof. An orifice mechanism at the distal end of the body communicates with the opening. The orifice mechanism includes an inner member having a ... | 05/01/2007 |
| 7211272 | Drug delivery device A drug delivery device for placement in the eye includes a drug core comprising a pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material impermeable to passage of the active agent and includes an opening for passage of... | 05/01/2007 |
| 7207982 | Osmotic pump with means for dissipating internal pressure The present invention includes an osmotic pump that includes a means for venting an osmotic composition included in the pump before the internal pressure of the pump has the opportunity to build to such an extent that the pump is structurally compromised, such as wh... | 04/24/2007 |
| 7192414 | Programmable implantable pump with accessory reservoirs and multiple independent lumen catheter An implantable pump system includes: an implantable pump having separate chambers or reservoirs; and a catheter having two or more reservoir-specific inlet ports directed into respective lumens of the catheter. In one embodiment, the distal tips of the respective lu... | 03/20/2007 |
