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Class 604/6.03 - Leukocyte


Subclass of Class 604 - Surgery
Definition: Subject matter wherein the constituents removed from the
No. of patents: 51
Last issue date: 01/10/2012


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NumberTitleIssue Date
8092413Multi-purpose tubing apparatus
An improved tubing device, preferably for use in the medical industry is provided. The tubing device provides a seamless transport path by using the tubing itself as the transport means without any other internally wetted parts, or connections, to provide a substant...
01/10/2012
7789847Methods and apparatus for leukoreduction of red blood cells
A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell separation and collection procedure. Such procedures invol...
09/07/2010
7682329Methods and apparatus for leukoreduction of red blood cells
A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell separation and collection procedure. Such procedures invol...
03/23/2010
7517333Blood processing systems and methods that employ an in-line, flexible leukofilter
Systems and methods separate pump the blood cells through an in-line leukofilter to a blood cell storage container. The leukofilter has a filtration medium enclosed within a flexile housing. The systems and methods can employ a fixture to restrain expansion of the f...
04/14/2009
7357897Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter
Blood processing systems and methods convey blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell st...
04/15/2008
7186231Blood component collection method
An object is to provide a blood component collection system capable of collecting a desired blood component of high quality. A blood component collection system 1 comprises a centrifugal separator 20 centrifuging blood into a plurality of components, f...
03/06/2007
7182865Device for separating whole blood under gravitational force
Method for separating whole blood into a leukocyte-depleted erythrocyte concentrate and thrombocyte-containing plasma, in which method whole blood is separated in a first step into an erythrocyte concentrate and plasma in a plasma filter and is then separated into a...
02/27/2007
7169547High concentration white blood cells as a therapeutic product
A therapeutic product formed from a high concentration of white blood cells having a high degree of cell viability. The white blood cells are sequestered from their normal population presence in whole blood by placing the blood into a container and preventing coagul...
01/30/2007
7105093Processing set and methods for processing and treating a biological fluid
Apparatus, systems and methods are disclosed for treating a biological fluid with light. A container of biological fluid is introduced into a fluid treatment chamber where it is contacted with light provided by one or more light sources in proximity to the fluid tre...
09/12/2006
7037428Integrated automatic blood processing unit
A system for automatically processing blood components is described. The system includes a console, which contains all motors, pumps, sensors, valves and control circuitry, and a unique disposable set that includes a cassette supporting a centrifuge with an improved...
05/02/2006
6994790Whole blood collection and processing method
A method is disclosed for collecting and processing whole blood. Whole blood is collected at several remote donor sites and transported to a central blood-processing center, where information regarding demand for blood products is used to direct processing of whole ...
02/07/2006
6964646Device and method for autologous blood transfusion
A device for autologous blood transfusion includes a centrifuge unit with an autotransfusion set rotatably mounted thereto. The autotransfusion set includes a separation unit for concentrating a cell fraction by centrifugation and a tubing system for providing a con...
11/15/2005
6875191Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter
Blood processing systems and methods convey blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell st...
04/05/2005
6796954Method for preparing leucocyte-free blood preparation and blood administration set
Preparing a leucocyte-free blood by introducing a leucocyte containing liquid into a leucocyte removal filter; removing a first fraction from an effluent that is discharged from the leucocyte removal filter; obtaining an effluent portion that is discharged after the...
09/28/2004
6713252Method for removing and reducing hepatitis C virus
Described is a method of removing and reducing HCV from the blood of an HCV-infected patient, which comprises carrying out, once a day for at least 5 straight days, a treatment of bringing the blood into contact with an adsorptive carrier having a higher affinity fo...
03/30/2004
6709412Blood processing systems and methods that employ an in-line leukofilter mounted in a restraining fixture
Systems and methods separate blood cells from whole blood and pump the separated blood cells through an in-line leukofilter to a blood cell storage container. The leukofilter has a filtration medium enclosed within a flexile housing. The systems and methods employ a...
03/23/2004
6695805Systems and methods for removing free and entrained contaminants in plasma
Systems and methods treat plasma carrying contaminants and leukocytes that are capable of entraining contaminants. The systems and methods separate leukocytes from the plasma by filtration, thereby removing contaminants entrained within leukocytes. The sy...
02/24/2004
6669905Systems and methods for collecting plasma that is free or virtually free of cellular blood species
Systems and methods treat plasma by separating targeted blood cell species such as red blood cells and platelets from the plasma by filtration through hydrophilic polyvinylidene fluoride (PVDF) membranes....
12/30/2003
6632191System and method for separating blood components
A system for collecting red blood cells (RBCs) and other blood components that reduces the need for human intervention. A disposable set is provided having a port, an RBC container, a centrifuge rotor having a variable total volume, and a filter, along wi...
10/14/2003
6498007Methods of treatment of disease using adsorbent carriers
The invention relates to a method for the removal of leucocytes from blood which comprises bringing blood that comprises infected leucocytes into contact with an adsorbent carrier that has a greater affinity for infected, activated and/or defective leucoc...
12/24/2002
6495366Uninterrupted flow pump apparatus and method
This invention describes a method for pumping or delivering fluids utilizing a flexible vessel subject to controlled pressures within another pressure vessel. The pressure vessel can be sourced with positive and/or negative (e.g., vacuum) pressure....
12/17/2002
6361692On line blood processing system for obtaining for storage a blood suspension having a reduced residual leukocyte population
Blood processing systems and methods establish on line communication between a container and a source of blood containing leukocytes and platelets, such as a human donor. The systems and methods create a centrifugal field between the source of blood and t...
03/26/2002
6251284Systems and methods which obtain a uniform targeted volume of concentrated red blood cells in diverse donor populations
Blood separation systems and methods draw whole blood from a blood donor selected from a population of blood donors. The whole blood of the selected blood donor has a known hematocrit value that varies within the population of blood donors according to mo...
06/26/2001
6200287Extracorporeal blood processing methods and apparatus
Improved extracorporeal blood processing methods and apparatus are disclosed. In one aspect of the invention, an extracorporeal method for the collection of platelets and red blood cells, and if desired plasma, is provided, wherein the collection of plate...
03/13/2001
6197207Method of reducing the possibility of transmission of spongiform encephalopathy diseases by blood products
Methods for reducing or preventing the transmission of transmissible spongiform encephalopathy through blood or blood products are provided. The methods require the intact removal of leukocytes that are present in a blood product or an intermediate of a b...
03/06/2001
6120474Blood component-recovering apparatus and a method for recovering blood components using the same
The present invention provides a blood component-recovering apparatus and a method for high-yield recovery of leukocytes captured in a filter of the blood component-recovering apparatus. The blood component-recovering apparatus includes a housing accommod...
09/19/2000
6102883Blood collection and separation process
A system compact enough to be located entirely beside the donor's chair, and able to process the blood while the donor is still resting in the chair after having donated the blood. The separated blood components (plasma and red blood cells) may be stored ...
08/15/2000
6071421Systems and methods for obtaining a platelet suspension having a reduced number of leukocytes
Systems and methods obtain a platelet suspension with reduced number of leukocytes by centrifugally separating whole blood into red blood cells, a suspension of platelets, and an intermediate layer comprising leukocytes. The systems and methods convey the...
06/06/2000
5980954Treatment of autoimmune diseases
An autoimmune vaccine is provided for administration to human patients to alleviate the symptoms of autoimmune diseases such as rheumatoid arthritis. The vaccine comprises an aliquot of the patient's blood, containing, inter alia, leukocytes having upregu...
11/09/1999
5935092Systems and methods for removing free and entrained contaminants in plasma
Systems and methods treat plasma carrying contaminants and leukocytes that are capable of entraining contaminants. The systems and methods separate leukocytes from the plasma by filtration, thereby removing contaminants entrained within leukocytes. The sy...
08/10/1999
5900377Method for isolating and radiolabeling leukocytes for use in vivo
Disclosed is a method for separating leukocytes from platelets. Blood serum is added to a centrifuge tube. A suspension containing leukocytes and platelets is then added to form a layer on top of the blood serum, the layer having a density less than the d...
05/04/1999
5865785Systems and methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes
Blood processing systems and methods establish on line communication between a container and a source of blood containing leukocytes and platelets, such as a human donor. The systems and methods create a centrifugal field between the source of blood and t...
02/02/1999
5855616Bioartificial pancreas
An implantable bioartificial pancreas device having an islet chamber containing glucose responsive and insulin-secreting islets of Langerhans or similar hormone secreting cells, one or more vascularizing chambers open to surrounding tissue, a semi-permeab...
01/05/1999
5804079Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
Systems and methods separate whole blood containing leukocytes in a first separation chamber into a first layer comprising red blood cells, a second layer comprising a suspension of platelets, and an interface between the first and second layers. The syst...
09/08/1998
5744047Leucocyte depleting filter device and method of use
Leucocyte depletion filter assemblies decrease the leucocyte content of a leucocyte-containing liquid at a flow rate of greater than about 25 milliliters per minute. These filter assemblies are suitable for use in an extracorporeal circuit. Methods for re...
04/28/1998
5738796Method for separating components from a biological fluid
The present invention provides for processing a biological fluid such as blood, to separate at least one component from the biological fluid, and to remove leukocytes from the separated component while returning the component depleted biological fluid to ...
04/14/1998
5670060Method for treating a biological fluid including transition zone material
A method for processing a biological fluid comprises separating a transition zone material from the biological fluid; processing the transition zone material to form a supernatant layer which includes platelets and a sediment layer which includes red bloo...
09/23/1997
5649903Apparatus and methods for generating leukocyte free platelet concentrate
Methods and devices for separating leukocytes from a leukocyte contaminated blood fraction by use of a rotating membrane filter apparatus. The invention includes methods/devices for preparing substantially leukocyte free platelet concentrate for therapeut...
07/22/1997
5630946Method for processing a biological fluid including leukocyte removal in an extracorporeal circuit
A method for removing undesirable material including leukocytes from a biological fluid in an extracorporeal circuit comprises passing a leukocyte containing biological fluid from a patient into a container; passing a portion of biological fluid from the ...
05/20/1997
5549834Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
Systems and methods are provided for reducing the number of leukocytes in cellular products like platelets collected in an on line or continuous blood separation processes. The systems and methods reduce the number of leukocytes from a cellular suspension...
08/27/1996
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