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...Daniel Webster invented a "bull plow" to pull out tree stumps. It didn't catch on because it was huge and required four oxen to pull it!
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| Number | Title | Issue Date |
| 8147479 | Monitoring stress on a therapeutic agent during patient delivery A physician, nurse, or other healthcare practitioner can deliver a therapeutic agent to a patient in a manner that maintains effectiveness of the therapeutic agent, via monitoring and controlling shear, stress, or other potentially detrimental effect. A gauge, meter... | 04/03/2012 |
| 8109919 | Device and method for rapid aspiration and collection of body tissue from within an enclosed body space Device and method for rapid extraction of body tissue from an enclosed body cavity. Hollow entry cannula with optional core element provides entry into body tissue space such as bone marrow. Aspiration cannula is inserted through cannula into body tissue and is mani... | 02/07/2012 |
| 8096984 | Cell delivery catheter and method A cell delivery catheter having one of more apearutres is used to positon and deliver cells to an implant site in a patient. ... | 01/17/2012 |
| 8066691 | Method and system for preparing soft tissue for grafting, enhancing grafting results, and grafting autologous fat to soft tissue such as the breast A method is disclosed for preparing a soft tissue site, and augmenting the soft tissue site, such as the breast(s) of a subject through use of devices that exert a distractive force on the breast(s) and grafting of autologous fat tissue such as domes with sealing ri... | 11/29/2011 |
| 8062283 | Methods and apparatus for treating infarcted regions of tissue following acute myocardial infarction Apparatus and methods are provided for treating an infracted region of myocardium following acute myocardial infarction by reducing the rate of blood flow through infracted region, and then injecting a solution containing stem cells, endothelial progenitor cells or ... | 11/22/2011 |
| 7819856 | Methods and apparatus for treating infarcted regions of tissue following acute myocardial infarction Apparatus and methods are provided for treating an infarcted region of myocardium following acute myocardial infarction by reducing the rate of blood flow through infarcted region, and then injecting a solution containing stem cells, endothelial progenitor cells or ... | 10/26/2010 |
| 7674250 | Methods of delivering therapeutic agents Devices and methods of delivering therapeutic agents to tissue are provided, which provide reduced outflow of therapeutic agents from an injection site. The methods include delivering one or more clot-promoting substances, such as platelets, fibrin and/or thrombin, ... | 03/09/2010 |
| 7358284 | Particulate acellular tissue matrix A method of processing an acellular tissue matrix to give a particulate acellular tissue matrix includes: cutting sheets of dry acellular tissue matrix into strips; cryofracturing the dry acellular tissue matrix strips at cryogenic temperatures; separating the resul... | 04/15/2008 |
| 7335223 | Apparatus for the treatment of body tissue An apparatus for treating body tissue includes a treatment instrument 1 for treating the body tissue and a measuring unit 3 for measuring the actual value of a parameter of the body tissue at at least one measuring point. An identifier 4 is conn... | 02/26/2008 |
| 7335210 | Endoscope and tools for applying sealants and adhesives and intestinal lining for reducing food absorption A first part of the inventive instrument comprises an insertion and removal device in the form of an endoscope which may be inserted through the mouth, pharynx, esophagus and stomach into the small intestine. The inside lumen of the endoscope contains two extendable... | 02/26/2008 |
| 7315758 | Transdermal delivery of therapeutic agent A device for the transdermal delivery of a therapeutic agent to a biological subject that includes a first electrode comprising a first array of electrically conductive microprojections for providing electrical communication through a skin portion of the subject to ... | 01/01/2008 |
| 7309395 | System for forming composite polymer dielectric film A system for depositing a composite polymer dielectric film on a substrate is disclosed, wherein the composite polymer dielectric film includes a low dielectric constant polymer layer disposed between a first silane-containing layer and a second silane-containing la... | 12/18/2007 |
| 7294511 | Methods for delivering nucleic acid molecules into cells and assessment thereof Methods for delivering nucleic acid molecules into cells and methods for measuring nucleic acid delivery into cells and the expression of the nucleic acids are provided. The methods are designed for introduction of large nucleic acid molecules, including artificial ... | 11/13/2007 |
| 7291604 | Methods of treating restenosis Restenosis in a subject can be treated by administering to a tissue, e.g., a blood vessel, of the subject an agent that increases SERCA activity. For example, a stent that is coated with the agent can be introduced into a blood vessel. ... | 11/06/2007 |
| 7270655 | Autologous material delivery apparatus and method An apparatus and method for providing autologous medical treatment to a patient. The apparatus is characterized by its provision of a harvest catheter operatively connected to a pump and a delivery catheter operatively connected to the pump downstream from the harve... | 09/18/2007 |
| 7204840 | Deep organ access device and method Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-... | 04/17/2007 |
| RE39533 | Process for intra-uterine fertilization in mammals and device for implementation thereof The A fertilization process comprises includes the following steps: a) a container (15) which can be introduced into, and lodged in, the uterine cavity of the mammal is provided; b) the container (15) is filled with a culture medium, at least one ovo... | 03/27/2007 |
| 7191011 | Access port indicator for implantable medical device The invention is directed to an implantable pump. The implantable pump has a port with light emitters indicating the location of the port. The port can be useful in providing bolus injections or the refilling of reservoirs. The light emitters can be arranged in vari... | 03/13/2007 |
| 7169127 | Pressure apron direct injection catheter A pressure apron for insitu plug formation is provided. In one embodiment an injection tube having a first channel and a piercing tip is provided, the first channel in fluid communication with a pressure source. In this embodiment, the injection catheter may also in... | 01/30/2007 |
| 7166719 | Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy Provided herein are compounds for detection, diagnosis and treatment of target tissues or target compositions, including hyperproliferative tissues such as tumors, using photodynamic methods. In particular, photosensitizer compounds that collect in hyperproliferativ... | 01/23/2007 |
| 7160716 | Device for inducing an immune response in cancer therapy A device for inducing an immune response in cancer therapy in which isolated living malignant tissue is enclosed in a space formed by a microporous membrane and a holder which is introduced into a body cavity so that macromolecular and cellular immune system compone... | 01/09/2007 |
| 7155279 | Treatment of movement disorders with drug therapy Introducing one or more stimulating drugs to the vagus nerve and/or one or more branches of the vagus nerve to treat movement disorders uses at least one implantable system control unit (SCU) with an implantable pump with at least one infusion outlet. Optional elect... | 12/26/2006 |
| 7125897 | Combined therapies for atherosclerosis treatment There is provided a combination treatment for slowing or arresting the progression and/or effecting the regression of atherosclerotic plaque deposits in a mammalian patient, said combination treatment including the administration to the patient of a cholesterol lowe... | 10/24/2006 |
| 7094219 | Intravenous fluid warming device A device for warming fluids being administered intravenously to a patient. The heating assembly comprising a warming pouch is wrapped and secured around a tube through which fluid is intravenously provided to the patient. ... | 08/22/2006 |
| 7074893 | Methods and compositions for the treatment of diseases associated with signal transduction aberrations The present invention relates generally to therapeutic methods and compositions. More particularly, methods and compositions to counteract and reverse disease-causing signaling defects in diseases with underlying signal transduction aberrations, including but not li... | 07/11/2006 |
| 7051734 | Medicament respiratory delivery device and method A medicament respiratory delivery device including a housing having a chamber including coaxially aligned inlet and outlet, a medicament cartridge located within the chamber having a passage therethrough and membranes sealing the passage having a burst pressure of l... | 05/30/2006 |
| 7053210 | Efficient synthesis of pyropheophorbide a and its derivatives A process for the preparation of pyropheophorbide a and its derivatives, including 3-devinyl-3-(1′-hexyloxy)ethyl-pyropheophorbide-a, otherwise known as HPPH, is provided. The process involves treating chlorin e6, in the form of its trimethyl ester, wit... | 05/30/2006 |
| 7047058 | Apparatuses, systems and methods for extravasation detection An apparatus for the detection of extravasation in an imaging procedure includes at least a first source of energy to supply imaging energy to tissue in the vicinity of a site and at least a first sensor to measure a signal resulting from the energy supplied to the ... | 05/16/2006 |
| 7045150 | Tellurium containing nutrient formulation and process for enhancing the cumulative weight gain or feed efficacy in poultry A novel nutrient formulation containing tellurium for use in poultry, and a method of feeding it which improves subsequent livability, cumulative feed efficacy or weight gain is disclosed. ... | 05/16/2006 |
| RE39086 | Cosmetic use of botulinum toxin for treatment of downturned mouth This invention provides the use of Botulinum toxin (BTX) to cause paralysis of a depressor anguli oris (DAO) musculature in a patient to alleviate downturn at corners of the patient's mouth. ... | 05/02/2006 |
| 7022135 | Film with highly porous vascular graft prostheses A vascular graft prosthesis having ingrowth-permissive lumenal wall features with a thin film or layer of sealant-like material placed at a lumenal wall location to promote improved transmural tissue growth and healing. ... | 04/04/2006 |
| 6979308 | Bioreactor design and process for engineering tissue from cells A scaled-up multi-coaxial fiber bioreactor, and variations of this bioreactor. The device is characterized by a hollow housing and an array of from about 20 to about 400 modules of hollow fibers, where each module includes at least three coaxial semipermeable hollow... | 12/27/2005 |
| 6958060 | Method for muscle delivery of drugs, nucleic acids and other compounds A method is disclosed for delivering molecules such as pharmaceutical drugs and nucleic acids into skeletal muscle in vivo. The molecule is first injected into the muscle at one or multiple sites. Immediately or shortly after injection, electrodes are placed flankin... | 10/25/2005 |
| 6939327 | Peel-away sheath A peel-away sheath for a catheter includes at least one weakened area in a non-longitudinal pattern, such as a helical pattern, along the length of the sheath. One embodiment of a catheter sheath includes a tube having at least one pull wire integrally located withi... | 09/06/2005 |
| 6936469 | Methods for delivering nucleic acid molecules into cells and assessment thereof Methods for delivering nucleic acid molecules into cells and methods for measuring nucleic acid delivery into cells and the expression of the nucleic acids are provided. The methods are designed for introduction of large nucleic acid molecules, including artificial ... | 08/30/2005 |
| 6916829 | Method for enhancing mutant enzyme activity in gaucher disease Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method ... | 07/12/2005 |
| 6899877 | Process for generating plasmin in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina A process for inhibiting vascular proliferation separately introduces components into the eye to generate plasmin in the eye in amounts to induce complete posterior vitreous detachment where the vitreoretinal interface is devoid of cortical vitreous remnants. The pr... | 05/31/2005 |
| 6862479 | Spinal cord stimulation as a therapy for sexual dysfunction One or more implantable system control units (SCU) apply one or more stimulating drugs and/or electrical pulses to a spinal section responsible for innervating the male reproductive organs. The SCU uses a power source/storage device, such as a rechargeable battery. ... | 03/01/2005 |
| 6846306 | Single cell electroporation A single cell electroporation assembly and method involve delivery of a substance into a single cell. The substance is combined into an electroporation fluid and placed into a container having a distal opening. The distal opening of the container is placed in proxim... | 01/25/2005 |
| 6805860 | Method of transluminal application of myogenic cells for repair or replacement of heart tissue A process is described for cellular repair of failing tissue of an organ if a patient's body. In the process, a catheter is positioned to provide an entry point for stem cell injection at the proximal end of the central lumen of the catheter external to the body and... | 10/19/2004 |
