A simulation environment for the sport of boxing utilizing a robotic machine interface system which carries a person.
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| Number | Title | Issue Date |
| 8167866 | Drug delivery system for accelerated subcutaneous absorption A method for accelerating subcutaneous absorption of a fluid or drug into the systemic circulation of a specific targeted tissue. A first drug operative to produce local capillary vasodilatation and/or increase the rate of bulk flow of solution through the interstit... | 05/01/2012 |
| 8029496 | Method and device for delivering drug to the trigone of the bladder Methods of treating functional disorders of the bladder in mammalian females are disclosed. A therapeutic compound is delivered directly into the trigone of the bladder. The therapeutic may be delivered to the trigone through the vaginal wall. A device for deliverin... | 10/04/2011 |
| 7931640 | Method for muscle delivery of drugs, nucleic acids and other compounds A method is disclosed for delivering molecules such as pharmaceutical drugs and nucleic acids into skeletal muscle in vivo. The molecule is first injected into the muscle at one or multiple sites. Immediately or shortly after injection, electrodes are placed flankin... | 04/26/2011 |
| 7537588 | Lateral needle injection apparatus and method A device and method for delivering and injecting fluid into heart tissue utilizing a laterally directed needle to increase injectate (fluid) retention in the heart tissue. The device may comprise a catheter having a shaft wherein the distal end of the shaft includes... | 05/26/2009 |
| 7462176 | Device for suction-assisted lipectomy and method of using same A device is described which allows simultaneous application of suction or vacuum for evacuation of fat with application of energy to the fat inside an opening in a cannula. A pair of electrodes is situated within the cavity of the cannula just under the surface of c... | 12/09/2008 |
| 7335367 | Treatment of chronic chalazion and hordeolum with botulinum toxin Chalazia and hordeola are the most common lesions occurring in the human eyelid, and often recurrences are managed by surgical intervention to remove fatty inclusions within the lid with associated inflammatory reaction. The present invention provides non-surgical m... | 02/26/2008 |
| 7220422 | Methods and compositions for treating eye disorders The present invention provides methods of treating an eye disorder. The methods comprise a step of locally administering a Clostridial toxin to the eye of a patient to treat the disorder. The eye disorder may be associated with an inflammation of the eye, inc... | 05/22/2007 |
| 7140371 | Surface topography method for determining effects of a botulinum toxin upon a muscle and for comparing botulinum toxins Skin topographical methods for quantifying pharmacodynamic parameters of a paralytic effect of a Clostridial toxin, such as a botulinum toxin upon a muscle, such as a frontalis muscle. The methods are effective in determining the potency of a Clostridial toxi... | 11/28/2006 |
| RE39086 | Cosmetic use of botulinum toxin for treatment of downturned mouth This invention provides the use of Botulinum toxin (BTX) to cause paralysis of a depressor anguli oris (DAO) musculature in a patient to alleviate downturn at corners of the patient's mouth. ... | 05/02/2006 |
| 7001602 | Use of botulinum toxin therapy for urinary incontinence and related disorders The present invention relates to methods for treating neurological-urological conditions. This is accomplished by administration of at least one neurotoxin. ... | 02/21/2006 |
| 6958060 | Method for muscle delivery of drugs, nucleic acids and other compounds A method is disclosed for delivering molecules such as pharmaceutical drugs and nucleic acids into skeletal muscle in vivo. The molecule is first injected into the muscle at one or multiple sites. Immediately or shortly after injection, electrodes are placed flankin... | 10/25/2005 |
| 6918903 | Device for suction-assisted lipectomy and method of using same A device is described which allows simultaneous application of suction or vacuum for evacuation of fat with application of energy to the fat inside an opening in a cannula. A pair of electrodes is situated within the cavity of the cannula just under the surface of c... | 07/19/2005 |
| 6776991 | Methods for treating priapism A method for treating priapism in a mammal by administration of a botulinum toxin. ... | 08/17/2004 |
| 6709427 | Systems and methods for delivering agents into targeted tissue of a living being The systems basically comprise a delivery system for accessing the targeted tissue within the living being and introduction of at least one agent at select locations in the into the myocardium and other select tissues. The delivery systems are arranged to access the... | 03/23/2004 |
| 6669662 | Perfusion catheter A perfusion catheter with a shaft having a lumen and a plurality of ports through the shaft. A rotatable core with a core groove is disposed within the lumen. The plurality of ports can be exposed by retraction of the core. The core can be rotated within ... | 12/30/2003 |
| 6569852 | Coatings and soaks for medical prosthetic devices comprising taurinamide derivatives and carboxylic acids and/or salts thereof The present invention relates to a method of inhibiting or preventing infection and blood coagulation in or near a medical prosthetic device after the device has been inserted in a patient by administering to the device a pharmaceutically effective amount... | 05/27/2003 |
| 6565553 | Needle assisted jet injector The invention relates to methods and devices for delivering medicament by jet injection to an injection site in a patient. The method includes inserting a needle into an insertion point, wherein the needle has a length of less than 5 mm and is operatively... | 05/20/2003 |
| 6544248 | Device for suction-assisted lipectomy and method of using same A surgical device and method allows simultaneous application of suction or vacuum to body tissue and application of energy to the body tissue drawn into a cannula. The device may be inserted laparoscopically into the body, and operated to suck body tissue... | 04/08/2003 |
| 6520927 | Method and device to prevent cardiac dysrhythmias A method and to treat dysrhythmias of the heart, for example atrial fibrillation, by creating artificial conduction pathways, fields or patterns. These artificial pathways or fields are created by injecting materials having desired electrical properties i... | 02/18/2003 |
| 6464680 | Ultrasonic enhancement of drug injection A method of enhancing cellular absorption of a substance delivered into a target region of a patient's body, comprising: (a) delivering the substance to the target region; and (b) directing vibrational energy to the target region, wherein the vibrational ... | 10/15/2002 |
| 6428528 | Needle assisted jet injector A needle assisted jet injector and method for jet injecting medicament are disclosed. In one embodiment of the injector, the needle is retractably located within an injector nozzle assembly. Upon activation of the energy source, a portion of the needle ex... | 08/06/2002 |
| 6358917 | Cosmetic use of botulinum toxin for treatment of downturned mouth This invention provides the use of Botulinum toxin (BTX) to cause paralysis of a depressor anguli oris (DAO) musculature in a patient to alleviate downturn at corners of the patient's mouth.... | 03/19/2002 |
| 6245052 | Methods, systems, and kits for implanting articles Methods, systems, and kits for subcutaneously implanting articles, such as drug inserts and reservoirs. The methods rely on percutaneously forming a tissue tract and radially dilating the tract to a diameter which permits introduction of the article. By f... | 06/12/2001 |
| 6217554 | Methods and apparatus for delivering substances into extravascular tissue Apparatus and methods for delivering a therapeutic or diagnostic agent into extravascular tissue surrounding a body passageway is provided comprising a catheter having a sheath, a tubular member, and a plurality of hollow needles on a distal end of the tu... | 04/17/2001 |
| 6126654 | Method of forming revascularization channels in myocardium using a steerable catheter An elongated steerable catheter for placement within a heart chamber, organ aperture or other body opening and having at least one center tube with hollow passageway for guiding a laser delivery means or other functional device to selected surfaces of a h... | 10/03/2000 |
| 6090097 | Aortic occluder with associated filter and methods of use during cardiac surgery A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the ... | 07/18/2000 |
| 5437291 | Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction Direct injection of sphincteric botulinum toxin is disclosed as an effective, safe and simple method of treatment for disorders of gastrointestinal muscle or smooth muscles elsewhere in the body, with results that appear to be sustained for several months... | 08/01/1995 |
| 5401243 | Controlled administration of chemodenervating pharmaceuticals The activity of chemodenervating agents can be ascertained by injecting locally a known quantity of the agent and determining the extent of inhibition of acetylcholine release about the locus resulting therefrom. Inhibition of acetylcholine release is ind... | 03/28/1995 |
| 5327913 | Percutaneus cardiomyoplasty method Cardiomyoplasty can be performed without significant incisions by using muscle segments as patches to reinforce the defective myocardium. This method involves the use of a dilator to form an opening within the diaphragm to provide an opening through which... | 07/12/1994 |
| 5304119 | Instrument for injecting implants through animal hide An instrument for injecting implants through animal hide is comprised of an injector having a tubular body divided into two adjacent segments with a hollow interior bore extending through the segments of the body. The second segment of the body has a gene... | 04/19/1994 |
| 5298019 | Controlled administration of chemodenervating pharmaceuticals This invention relates to a method for controlled administration of chemodernervating agents such as botulinum toxin-derived pharmaceutical, useful in attenuating neural stimulation and spasmodic activity of muscle. The method involves administration of n... | 03/29/1994 |
| 5273525 | Injection and electroporation apparatus for drug and gene delivery An apparatus for implanting macromolecules such as genes, DNA or pharmaceuticals into a preselected tissue region such as a muscle or an organ of a patient. A modified syringe is provided for injecting a predetermined quantity of a fluid medium carrying t... | 12/28/1993 |
| 5078680 | Automatic injector for emergency treatment A method of treating a patient with liquid medicament under circumstances where intravenous injection is not practical but the fast response time of an intravenous injection is desirable, including the treatment of individuals undergoing heart attack symp... | 01/07/1992 |
| 5053005 | Chemomodulation of curvature of the juvenile spine Disclosed is a non surgical method of modulating spinal curvature in developing vertebrates. Agents capable of temporarily interfering with neuromuscular transmission, e.g., botulinum toxin, are injected into the musculature of the back to create an imbal... | 10/01/1991 |
| 4932936 | Method and device for pharmacological control of spasticity A method and apparatus for pharmacological control of spastic urethral sphincters, particularly in patients with spinal cord injuries, includes a special monopolar electrode/needle (30) adapted for insertion through a cystoscope (46) in electrical isolati... | 06/12/1990 |
| 4755169 | Automatic medicament ingredient mixing and injecting apparatus An automatic injector apparatus comprising an outer housing assembly, a hypodermic needle, first and second containers, a first liquid medicament ingredient in the first container and a second medicament ingredient in the second container, first and secon... | 07/05/1988 |
| 3977402 | Injection apparatus and method with automatic aspiration feature An apparatus for intramuscular or subcutaneous injection of medications featuring automatic aspiration capability is disclosed herein. In a preferred embodiment the apparatus is completely self-contained, i.e., all components required for injection includ... | 08/31/1976 |