...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 7993324 | Cerebral perfusion augmentation Methods are provided for partial aortic occlusion for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. The descending aorta is accessed. A device is then located downstream from the takeoff of the brachiocephalic artery. ... | 08/09/2011 |
| 7981103 | Method of treating a stiffened blood vessel A method of treating a stiffened blood vessel (2) is disclosed. The method comprises at least substantially encasing a portion of the blood vessel (2) with an elastic membrane (6) formed of biocompatible material such the membrane (6) eng... | 07/19/2011 |
| 7780645 | Method of delivering embolic particles to an aneurysm A method of delivering embolic particles to an aneurysm includes inserting a delivery catheter into the vasculature of a patient and directing the distal end of the delivery catheter to a pre-selected deployment site. Embolic particles are loaded into the delivery c... | 08/24/2010 |
| 7763009 | Tri-functional cannula for retinal endovascular surgery A tri-functional cannula combines the functions of tissue Plasminogen Activator (tPA) solution delivery, illumination and venous pressure measurement. The cannula utilizes a tapered hollow-core optical fiber having an inlet for tPA solution, an attached fiber optic ... | 07/27/2010 |
| 7744583 | Systems and methods of de-endothelialization Apparatus and methods for treating a wall of an aneurysm formed in a vessel includes introducing a tubular member into the body lumen until a distal end of the tubular member is located within the aneurysm. A fluid is delivered via a lumen of the tubular member into... | 06/29/2010 |
| 7686799 | Deployment system for myocardial cellular material A catheter-based deployment system for deploying cellular material (22) into the heart muscle (25). The deployment system includes a guiding catheter (19) and a needle assembly (31) capable of sliding within the guiding catheter. The need... | 03/30/2010 |
| 7503913 | Methods and compositions for use in perfusion applications Methods and compositions for use in perfusion applications are provided. In the subject methods, a subject or derivative thereof, e.g. isolated organ or tissue, is infused, perfused and/or transfused with at least two fluid compositions. The first fluid composition ... | 03/17/2009 |
| 7481803 | Intra-aortic renal drug delivery catheter A catheter for delivering a therapeutic or diagnostic agent to a branch blood vessel of a major blood vessel, generally comprising an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an ex... | 01/27/2009 |
| 7473247 | Intradermal delivery of vaccines and gene therapeutic agents via microcannula The present invention relates to methods and devices for administration of vaccines and gene therapeutic agents into the intradermal layer of skin. ... | 01/06/2009 |
| 7431717 | Central nervous system administration of medications by means of pelvic venous catheterization and reversal of Batson's Plexus An infusor system for administering medications to a venous blood vessel in the body of a patient. The infusor system includes a flexible, elongated delivery tube having opposite ends. One of the ends is couplable to a supply of liquid medication, which is remote fr... | 10/07/2008 |
| 7419482 | Systems and methods for delivering agents into targeted tissue of a living being A method of vascularizing cardiac tissue using an instrument through the vascular system to an entry situs located at or adjacent the cardiac tissue is provided including providing a flowable agent comprising microspheres or microparticles having a particulate size ... | 09/02/2008 |
| 7413556 | Sheath for use with an ultrasound element A system for delivering ultrasound energy to a treatment section in a vessel is disclosed. The system includes a sheath with a utility lumen and an energy delivery section at least partially constructed from a material which transmits ultrasound energy. The system a... | 08/19/2008 |
| 7371228 | Delivery of therapeutics to treat aneurysms A method and device for the treatment of an aneurysm are provided. Different therapeutic agents are delivered to the aneurysmal site by a reservoir and delivery means in a localized, and, in some embodiments, time-released regimen, to treat, limit and reduce the sev... | 05/13/2008 |
| 7357937 | Perfluorocarbon emulsions with non-fluorinated surfactants A stable FC emulsion is described. The FC emulsion of the present invention comprises a continuous FC immiscible hydrophilic liquid phase and a dispersed phase comprising FC suspended as droplets within the continuous phase. The emulsion further comprises an emulsif... | 04/15/2008 |
| 7338511 | Solid embolic material with variable expansion A solid embolic material that is capable of filling irregularly shaped and asymmetrical vascular defects in a controlled and predictable manner, without the difficulties associated with delivery of the embolic material through a microcatheter and containment of the ... | 03/04/2008 |
| 7331938 | Medicine liquid injection device where medicine liquid sucked up from medicine liquid tank and injected to subject does not flow back The present invention provides liquid injector 100 wherein syringe 210 sucks a liquid from liquid tank 200 in a suck state in which connection switch mechanism 105 connects syringe tube 103 to tank tube 102, and syringe 2... | 02/19/2008 |
| 7329402 | Methods of imaging and treatment Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The... | 02/12/2008 |
| 7328064 | Electroporation device and injection apparatus An apparatus is provided for injecting a fluid into body tissue, the apparatus comprising: a hollow needle; and fluid delivery means, wherein the apparatus is adapted to actuate the fluid delivery means i... | 02/05/2008 |
| 7322960 | Catheter with puncture sensor A catheter for percutaneous insertion includes a sheath portion, an insertion member, an injection needle, and paired electrodes. The sheath portion has a lumen extending therein. The insertion member is disposed slidably in the lumen of the sheath portion and provi... | 01/29/2008 |
| 7314466 | Minimally invasive vascular surgery A mixture for intravenous injection to treat damaged vascular structures contains a mixture of carbamide peroxide and a sclerosing agent. The injected mixture expresses blood from the affected vascular structure by formation of bubbles, in situ. The bubbles carry th... | 01/01/2008 |
| 7302289 | Readable probe array for use A disposable high density optically readable polydeoxynucleotide array with integral fluorescence excitation and fluorescence emission channels is described. The compact array size allows integration into several types of interventional devices such as catheters, gu... | 11/27/2007 |
| 7300662 | Drug/drug delivery systems for the prevention and treatment of vascular disease A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f... | 11/27/2007 |
| 7291133 | Device for the metered administration of a fluid drug A device for the metered administration of a fluid drug. The device has a container having a piston for administering the fluid drug through an outlet of the container, a catheter connected to the outlet of the container, the catheter having a front end facing away ... | 11/06/2007 |
| 7285113 | Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems A device for the transport of fluids through a biological barrier includes a number of microneedles projecting from the front face of a substrate. A conduit is associated with each of the microneedles to provide a fluid flow path for transport of fluid through a hol... | 10/23/2007 |
| 7279002 | Cutting stent and balloon A stent or sheath having one or more cutting blades may be constructed for implantation in the body. A balloon having one or more cutting blades may be used with a stent or a sheath. ... | 10/09/2007 |
| 7273469 | Modified needle catheter for directional orientation delivery Methods and apparatus for delivering a treatment agent through a percutaneous delivery apparatus are herein disclosed. In some embodiments, an apparatus can include an expandable body with at least one delivery cannula having a lumen therethrough coupled to an exter... | 09/25/2007 |
| 7247149 | Contact and penetration depth sensor for a needle assembly An apparatus is disclosed. The apparatus includes a needle to contact and penetrate tissue. The apparatus also includes a device coupled to the needle, wherein the device detects the needle contacting the tissue, and measures depth of tissue penetration. ... | 07/24/2007 |
| 7247275 | Gel extraction device A gel extraction device comprising a hollow cutting member and a plunger ejector member. The hollow cutting member has a proximal tubular body terminating at one end in a circular rim having oppositely disposed spring engaging structures and a distal sloped transiti... | 07/24/2007 |
| 7241284 | Method of inhibiting restenosis A method of inhibiting restenosis is disclosed. The method includes reducing contaminants during manufacturing of angioplasty devices and during angioplasty procedures. An angioplasty device is preferably examined for contaminants prior to the angioplasty procedure,... | 07/10/2007 |
| 7241286 | Flush catheter with flow directing sheath A flush catheter is provided which is configured to be introduced into an orifice to create a flush zone therein. The flush catheter includes a catheter body having an inner cavity, the inner cavity being configured to communicate with a source of flush solution, on... | 07/10/2007 |
| 7229473 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 06/12/2007 |
| 7223286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/29/2007 |
| 7217286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/15/2007 |
| 7211054 | Method of treating a patient with a neurodegenerative disease using ultrasound The present invention provides methods for treating patients with ultrasound to promote healing. In particular, the present invention provides a method for improving blood flow to ischemic tissue by applying ultrasound to ischemic tissue. The invention also provides... | 05/01/2007 |
| 7204824 | Medical liquid delivery device Disclosed herein are novel liquid delivery catheters, and methods and kits implementing the same. The disclosed catheters are particularly useful for localized delivery of a liquid caustic agent to treat various defects associated with malformations and injuries res... | 04/17/2007 |
| 7201918 | Compositions, systems and methods for treatment of defects in blood vessels Methods and systems are provided for treating a vascular structure having a defect, for example, a cerebral artery having a weakened wall that has formed an aneurysm. The methods include substantially entrapping a quantity of blood within a vascular defect, and intr... | 04/10/2007 |
| 7189209 | Method for using acoustic shock waves in the treatment of a diabetic foot ulcer or a pressure sore A method of treating pathological conditions associated with bone and musculoskeletal environments and soft tissues involves applying acoustic shock waves to cause localized trauma, including micro-disruptions, non-osseous tissue stimulation, increased vascularizati... | 03/13/2007 |
| 7187971 | Medical fluid delivery system A medical fluid delivery system includes an implantable medical lead and a fluid delivery device; the device is adapted to pass through a proximal port, a lumen and a distal port of the lead. The fluid delivery device includes a tissue piercing distal tip and a pre-... | 03/06/2007 |
| 7182755 | Method and apparatus for treatment of thrombosed hemodialysis access grafts A method for the treatment of thrombosed hemodialysis access grafts or fistulas defining a shunt positioned between an arterial side and a venous side is achieved by inserting a balloon catheter within the shunt, wherein the balloon catheter includes a distal balloo... | 02/27/2007 |
| 7179251 | Therapeutic delivery balloon The present invention regards a therapeutic delivery balloon and includes a system for delivering therapeutic to an irregular interior vessel surface. This system includes a catheter having a proximal end, a distal end, and an internal lumen; a source of fluid in co... | 02/20/2007 |