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| Number | Title | Issue Date |
| 8048057 | Catheter for uniform delivery of medication A catheter is provided for uniform distribution of fluid medication within an anatomical region. One embodiment of the catheter is comprised of an elongate tubular catheter body defining a lumen. A distal end of the lumen is closed and a portion of the catheter body... | 11/01/2011 |
| 7967806 | Method of delivering a fluid medication to a patient in flex mode A method of delivering a fluid medication to a patient under direction of a medical professional continually at a basal rate and at an interval rate in each of a plurality of time slots over a specified period of time. The total dose of the fluid medication to be de... | 06/28/2011 |
| 7811274 | Method for treating chronic obstructive pulmonary disease A ventilation bypass system which alleviates symptoms of chronic obstructive pulmonary disease by allowing air to exit the lung of a patient through the thoracic wall bypassing the natural airways. A pleurodesis is formed between the visceral and parietal membranes ... | 10/12/2010 |
| 7811275 | Methods of implanting an injection port A surgical fastening system for implantable devices is disclosed. The implantable device may contain a plurality of fasteners in pre-deployment position, may have a housing fitted over or around it which contains a plurality of fasteners in pre-deployment position, ... | 10/12/2010 |
| 7662140 | Method of delivering drug to brain via spinal cord In various aspects, systems and methods involve catheters having infusion sections with permeable membranes that develop significant back pressure to enhance uniform delivery of the drug over an infusion section; catheters that have two or more infusion sections spa... | 02/16/2010 |
| 7427280 | Method, system and device for treating disorders of the pelvic floor by delivering drugs to various nerves or tissues Described are implantable devices and methods for treating various disorders of the pelvic floor by delivering one or more drugs to a patient's hypogastric nerve or branches or portions thereof, prostatic plexus nerve or branches or portions thereof, sacral splanchn... | 09/23/2008 |
| 7338465 | Infusion device and method thereof The disclosures made herein relate to an infusion device specifically adapted for syringe injections. In one embodiment of the disclosures made herein, an infusion device comprises a body including an accessible surface having a single inlet port therein, an engagem... | 03/04/2008 |
| 7337006 | Methods and systems for modulating neural tissue Some embodiments of the present invention provide methods and systems for modulating neural tissue including systems and components for selective stimulation and/or neuromodulation of targeted neural tissue. Targeted neural tissue may include one or more ganglia inc... | 02/26/2008 |
| 7311980 | Polyactive/polylactic acid coatings for an implantable device A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ... | 12/25/2007 |
| 7279174 | Stent coatings comprising hydrophilic additives A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically... | 10/09/2007 |
| 7279457 | Rapid acting drug delivery compositions Drug formulations for systemic drug delivery with improved stability and rapid onset of action are described herein. The formulations may be administered via buccal administration, sublingual administration, pulmonary delivery, nasal administration, subcutaneous adm... | 10/09/2007 |
| 7271234 | Polyarylates for drug delivery and tissue engineering Biocompatible polyarylates of tyrosine-derived diphenol compounds and poly(alkylene oxide) dicarboxylic acids, articles formed therefrom and therapeutic uses are disclosed. ... | 09/18/2007 |
| 7250154 | Radio-opaque polymeric biomaterials A radio-opaque dihydroxy compound substituted with at least one bromine or iodine atom. Radio-opaque medical implants and drug delivery devices and methods for therapeutic site-specific or systemic drug delivery comprising implanting in the body of a patient are als... | 07/31/2007 |
| 7244443 | Polymers of fluorinated monomers and hydrophilic monomers A polymer of fluorinated monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains a polymer of fluorinated monomers and another biocompatible polymer. The polymer of fluorinated monomers or polymer blend described herein and o... | 07/17/2007 |
| 7242982 | Overmold for a modular implantable medical device A modular implantable medical device permits implantable medical devices to have a smaller profile in order to better fit into locations within the human body. A modular implantable medical device separates various functional components of the implantable medical de... | 07/10/2007 |
| 7242981 | System and method for controlling an implantable medical device subject to magnetic field or radio frequency exposure A system for controlling an implantable medical device (e.g., a drug delivery device) susceptible to malfunctioning during exposure to a magnetic field and/or Radio Frequency field (e.g., during a magnetic resonance imaging procedure) and a method for operating the ... | 07/10/2007 |
| 7232429 | Medical devices A medical device includes a cavity communicable with a body to deliver or to receive a fluid, and a radiation source configured to expose a portion of the cavity to radiation. ... | 06/19/2007 |
| 7229473 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 06/12/2007 |
| 7229458 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of cartridges each with a distal port and a proximal port. A plurality of penetrating members are provided, each coupled to a cartridge and having a sharpened distal tip and a shaft portion slidably disposed within th... | 06/12/2007 |
| 7223286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/29/2007 |
| 7217286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/15/2007 |
| 7212870 | Dual helix active fixation stimulation lead An implantable lead for use with an implantable medical device includes a lead body with first and second electrical conductors extending between its proximal and distal ends. An electrical connector at the proximal end of the lead body includes terminals electrical... | 05/01/2007 |
| 7184840 | Implantable lead with isolated contact coupling An implantable lead for a medical device with an isolated contact connection for connecting a conductor to a contact reduces the opportunity for conductor material to migrate to a contact or into a patient. The implantable lead comprises a lead body having a proxima... | 02/27/2007 |
| 7142911 | Method and apparatus for monitoring drug effects on cardiac electrical signals using an implantable cardiac stimulation device An implantable cardiac stimulation device, such as a pacemaker or Implantable Cardioverter Defibrillator, is configured to automatically monitor the effects of antiarrhythmic drugs on cardiac electrical signals within a patient to verify the efficacy of the drugs ta... | 11/28/2006 |
| 7108685 | Patch stabilization of rods for treatment of cardiac muscle The present invention relates to a system and method for the delivery of therapeutic agents, such as therapeutic drugs or genetic material, into the muscle or tissue that minimizes the loss of therapeutic agents due to contraction of the muscle. In one embodiment, a... | 09/19/2006 |
| 7101356 | Implantable vascular access device An implantable dual chambered catheter device includes a first chamber and a second chamber integrally joined. The first chamber includes a hollow first elastomeric member contained within a first slotted outer housing. A first end of the first elastomeric member is... | 09/05/2006 |
| 7099718 | Neural stimulation lead fixation An implantable lead having at least one electrode contact at or near its distal end prevents undesirable movement of the electrode contact from its initial implant location. One embodiment relates to a spinal cord stimulation (SCS) lead. A balloon may be positioned ... | 08/29/2006 |
| 7094256 | Coatings for implantable medical device containing polycationic peptides Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coatings include carboxylated acrylates and polycationic peptides, for example R7. ... | 08/22/2006 |
| 7083593 | Programmable implantable pump with accessory reservoirs and multiple independent lumen catheter An implantable pump system includes: (1) an implantable pump having separate chambers or reservoirs, at least one of which is coupled to the pump so as to allow a programmable rate of delivery of the medication stored in the pump chamber or reservoir, the other cham... | 08/01/2006 |
| 7070798 | Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine A coating for an implantable medical device is disclosed. The coating comprises a polymer and an amino acid chemically bonded, attached or conjugated to the polymer. In one embodiment, the coating can include a therapeutic substance. In lieu of bonding the amino aci... | 07/04/2006 |
| 7070591 | Vascular access port with physiological sensor A combined vascular access port and physiologic parameter monitoring device. The vascular access port and the monitoring device may be connected by a cooperative geometry. The vascular access port and the monitoring device may be implanted at the same time and in th... | 07/04/2006 |
| 7067127 | GIcNAc phosphotransferase of the lysosomal targeting pathway The present invention provides nucleotide and amino sequences of the lysosomal targeting pathway enzyme GlcNAc-phosphotransferase, methods of producing and methods of purifying this enzyme. ... | 06/27/2006 |
| 7063691 | Implantable reservoir and system for delivery of a therapeutic agent There is disclosed method and apparatus for retaining a reservoir for a therapeutic agent between the scalp and cranium of a subject, including providing a deformable pouch or rigid cylinder for dispensing the therapeutic agent from the reservoir to a location in th... | 06/20/2006 |
| 7056523 | Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine An implantable medical device, such as a stent, is disclosed comprising an amino acid or a polypeptide bonded to a plasma polymerized film layer formed on the device. A method of manufacturing the same is also disclosed. ... | 06/06/2006 |
| 7052486 | Method and system for treating depressive and anxiety disorders A method and system for treating depressive and anxiety disorders is disclosed. The method and system of the present invention comprises operating a programmable pump for the delivery of at least one therapeutic substance into the cerebrospinal fluid of a patient fo... | 05/30/2006 |
| 7048729 | Catheter and method of fluid removal from a body cavity A catheter comprises a catheter body having a wall defining a lumen therein and having plural holes defined through the wall in a pattern which prevents loculation, migration and blockage of a fluid flow through the lumen, the catheter body having a tissue-puncture ... | 05/23/2006 |
| 7047084 | Apparatus for directionally stimulating nerve tissue This invention relates to an apparatus and method for making such apparatus for providing controlled and directional stimulation patterns for tissue stimulation. The apparatus may be useful in stimulation nervous tissue in the brain, about the spinal cord, on nerve ... | 05/16/2006 |
| 7033602 | Polycationic peptide coatings and methods of coating implantable medical devices Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed. ... | 04/25/2006 |
| 7033335 | Guidewire compatible port and method for inserting same An access port assembly having an attachable catheter allows for inserting a guidewire into the catheter to aid in the placement of the integral catheter while still attached to the access port assembly. A method is described for placing an access port fixedly attac... | 04/25/2006 |
| 7025741 | Arteriovenous access valve system and process An arteriovenous graft system is described. The arteriovenous graft system includes an arteriovenous graft that is well suited for use during hemodialysis. In order to minimize or prevent arterial steal, at least one valve device is positioned at the arterial end of... | 04/11/2006 |
