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| Number | Title | Issue Date |
| 8160693 | Irrigation probe for ablation during open heart surgery An irrigation ablation probe comprises a generally rigid probe body and a handle mounted to the proximal end of the probe body. The generally rigid probe body comprises an ablation electrode at its distal end having at least one irrigation opening through which flui... | 04/17/2012 |
| 8095214 | Perivascular leak repair system The perivascular leak repair system, and method of using the same, of the present invention provides a sealant reservoir 102 with a repair catheter 104 operably attached; a flow control device 106 disposed between the sealant reservoir 102 | 01/10/2012 |
| 8005538 | Stimulating catheter An apparatus for delivery of a substance to an anatomical region in a body can include a catheter comprising a catheter body, and one or more electrically conductive elements supported by the catheter body and in electrical communication with one or more sources of ... | 08/23/2011 |
| 8005537 | Robotically controlled intravascular tissue injection system A robotic catheter system includes a controller including a master input device and instrument driver in communication with the controller. An elongate flexible guide instrument is operatively coupled to the instrument driver. A fluid injection needle may be advance... | 08/23/2011 |
| 7996078 | Systems and methods of photodynamic-based cardiac ablation via the esophagus Systems and methods for photodynamic ablation of cardiac tissue via an esophagus are disclosed. An exemplary system includes an ablation catheter having an expandable distal end for securing the ablation catheter in the esophagus. The distal end of the ablation cath... | 08/09/2011 |
| 7937143 | Methods and apparatus for inducing controlled renal neuromodulation Methods and apparatus are provided for inducing, monitoring and controlling renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. In some embodiments, tissue impedance, conductance or conductivity may be monitored to det... | 05/03/2011 |
| 7925341 | Irrigation probe for ablation during open heart surgery An irrigation ablation probe comprises a generally rigid probe body and a handle mounted to the proximal end of the probe body. The generally rigid probe body comprises an ablation electrode at its distal end having at least one irrigation opening through which flui... | 04/12/2011 |
| 7912539 | Catheter-based, dual balloon photopolymerization system A system for applying a polymer (hydrogel) to the inner surface of a vessel by photopolymerization includes a catheter having a first inflatable member and a guidewire having a second inflatable member. The catheter has an extended tip distal to the first inflatable... | 03/22/2011 |
| 7844328 | Liquid injector for controlling injection of liquid in real-time according to injection graph A liquid injector displays a plotting chart image whose vertical axis represents liquid injection rates and horizontal axis represents liquid injection times. When an injection graph which represents a liquid injection rate at each quantity of the liquid to be injec... | 11/30/2010 |
| 7840260 | Iontophoretic intra-tympanic drug delivery system A system, method, and apparatus for iontophoretically delivering medically-active ions beyond the tympanic membrane, into a middle ear portion of a patient, and to an area or structure of the middle or inner ear that is targeted for treatment. The system and apparat... | 11/23/2010 |
| 7805188 | Anesthesia conduction catheter for delivery of electrical stimulus A catheter is comprised of a flexible cylindrical tube defining a proximal portion and a distal portion terminating in a distal tip. The tube has a plurality of openings formed therethrough to form a diffusion area. The catheter includes a conductive end cap enclosi... | 09/28/2010 |
| 7783346 | Illuminated infusion cannula A transparent illuminated infusion cannula is provided for illuminating an area during eye surgery. An optical fiber may be spaced a certain distance away from the cannula such that fluid flow around the distal end of the fiber and into the transparent cannula may o... | 08/24/2010 |
| 7764994 | Irrigation probe for ablation during open heart surgery An irrigation probe useful for ablation during open heart surgery is provided. The irrigation probe comprises a generally rigid probe body and a handle mounted to the proximal end of the probe body. The generally rigid probe body has an electrode at its distal end h... | 07/27/2010 |
| 7761148 | Irrigation probe for ablation during open heart surgery An irrigation probe useful for ablation during open heart surgery is provided. The irrigation probe comprises a generally rigid probe body and a handle mounted to the proximal end of the probe body. The generally rigid probe body has an electrode at its distal end h... | 07/20/2010 |
| 7664545 | Electrode assembly for constant-current electroporation and use The present invention relates to a modular electrode system, and its use, for facilitating the introduction of a macromolecule into cells of a selected tissue in a body or plant. The modular electrode system comprises a non-symmetrically arranged plurality of needle... | 02/16/2010 |
| 7653432 | Catheter-based, dual coil photopolymerization system A system for applying a polymer (hydrogel) to the inner surface of a vessel by photopolymerization includes an inner catheter received within an outer catheter and a fluid channeling structure mounted on the catheters with its proximal end attached to the outer cath... | 01/26/2010 |
| 7577477 | Perivascular leak repair system The perivascular leak repair system, and method of using the same, of the present invention provides a sealant reservoir with a repair catheter operably attached; a flow control device disposed between the sealant reservoir and the repair catheter, and the flow cont... | 08/18/2009 |
| 7570992 | Electrical field therapy with reduced histopathological change in muscle In vivo methods are provided for using an electric field to delivery therapeutic treatment to a subject while reducing inducement of histopathological change in the target muscle tissue, such as is associated with induction or amplification of an immune response cau... | 08/04/2009 |
| 7515957 | Catheter-based, dual balloon photopolymerization system A system for applying a polymer (hydrogel) to the inner surface of a vessel by photopolymerization includes a catheter having a first inflatable member and a guidewire having a second inflatable member. The catheter has an extended tip distal to the first inflatable... | 04/07/2009 |
| 7457661 | Catheter-based, dual coil photopolymerization system A system for applying a polymer (hydrogel) to the inner surface of a vessel by photopolymerization includes an inner catheter received within an outer catheter and a fluid channeling structure mounted on the catheters with its proximal end attached to the outer cath... | 11/25/2008 |
| 7437189 | Iontophoresis device An iontophoresis device includes: a first electrode; a biological interface contact member including a substrate having a front surface and a rear surface, and a plurality of needles that protrude from the front surface of the substrate and can be inserted into a bi... | 10/14/2008 |
| 7422565 | Support element for an extracorporeal fluid transport line A rigid support element for an infusion line for medical use has a first and second portion rigidly connected to each other and capable of holding a first length of tubing. The first portion incorporates a continuous separator for separating fluid into a gaseous por... | 09/09/2008 |
| 7415306 | Transdermal delivery system for anti-emetic medication The present invention provides a transdermal delivery system for hydrophilic anti-emetic agents and methods of using thereof. The system includes an anti-emetic hydrophilic adhesive composition of a hydrophilic polymer and hydrophilic anti-emetic agent, a patch cont... | 08/19/2008 |
| 7415302 | Method and system for leading macromolecule substances into living target cells A method and system for leading macromolecule substances into target cells includes an image picking unit, an image merging unit, an injection unit, and an energy conversion module. The image picking unit is used for picking up the three-dimensional (3D) and the 3D ... | 08/19/2008 |
| 7412284 | Apparatus for electroporation mediated delivery for drugs and genes A device for in vivo electroporation therapy comprising an electrode applicator with at least two pairs of electrodes arranged relative to one another to form an array and a power supply. The device is used to generate an electric field in a biological sample and ef... | 08/12/2008 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7364562 | Anti-clotting apparatus and methods for fluid handling system A method for maintaining clear passageways in an extracorporeal blood flow system. The method comprises intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. Also disclosed is an extracorporeal blood flow ... | 04/29/2008 |
| 7364748 | Controlled morphologies in polymer drug for release of drugs from polymer films The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is incorporated into the drug-enriched phase. ... | 04/29/2008 |
| 7363075 | Transdermal delivery system for dried particulate or lyophilized medications The present invention provides a system for transdermal delivery of dried or lyophilized pharmaceutical compositions and methods using thereof. The system comprises an apparatus for facilitating transdermal delivery of an agent that generates hydrophilic micro-chann... | 04/22/2008 |
| 7359601 | Device and method for delivery of long wavelength laser energy to a tissue site A laser energy delivery device is provided that is suitable for irradiating a body tissue with relatively long wavelength laser energy in the presence of an aqueous liquid without significant absorption of the laser energy by the liquid. The device includes an elong... | 04/15/2008 |
| 7357798 | Systems and methods for electrosurgical prevention of disc herniations The present invention provides systems and methods for selectively applying electrical energy to a target location within a patient's body, particularly including tissue in the spine. The present invention applies high frequency (RF) electrical energy to one or more... | 04/15/2008 |
| 7354391 | Implantable radiotherapy/brachytherapy radiation detecting apparatus and methods An interstitial brachytherapy apparatus and method for delivering and monitoring radioactive emissions delivered to tissue surrounding a resected tissue cavity. The brachytherapy device including a catheter body member having a proximal end, a distal end, and an out... | 04/08/2008 |
| 7351246 | Minimally invasive, sustained, intra-tympanic drug delivery system A convenient and preferably wearable system and method for implementing the controlled and sustained delivery of a medical liquid through the tympanic membrane and into the middle ear including port structure that produces a minimal opening in the membrane, a wearab... | 04/01/2008 |
| 7347835 | Process for producing pad base for endermism, and pad base for endermism, and injection needle The present invention provides a production process for obtaining a pad base for endermism capable of administering a drug in the skin without vibration. One side end of a thin metal wire is immersed in a solution containing a synthetic resin raw material in a lengt... | 03/25/2008 |
| 7341569 | Treatment of vascular occlusions using ultrasonic energy and microbubbles In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble... | 03/11/2008 |
| 7338434 | Method and system for organ positioning and stabilization This invention provides a heart positioning device, method and system for positioning, manipulating, holding, grasping, immobilizing and/or stabilizing a heart. The heart positioning device may include a suction head and a shaft with a means for remotely changing th... | 03/04/2008 |
| 7338430 | Gynecological brachytherapy applicator and system A vaginal brachytherapy applicator is versatile to different anatomies and more comfortable to the patient than prior applicators. An inflatable balloon on a shaft may be inelastic or elastic. In one embodiment the shaft is rotatable relative to the balloon for enab... | 03/04/2008 |
| 7340301 | Defibrillator system The invention provides a portable defibrillation system (2), including: a high voltage switch, and current control circuit (16) connectable to and fed by a power source (6); a high voltage transformer (14) fed by the current control circu... | 03/04/2008 |
| 7338473 | Pneumoseal trocar arrangement A cannula assembly for the maintenance of an operative pneumoperitoneum in a patient comprising an elongated cannula having a proximal end and a distal end. A removable valve is securely arranged in the proximal end of the cannula to provide a seal and minimize the ... | 03/04/2008 |
| 7335159 | Endoscope having auto-insufflation and exsufflation An endoscopic imaging system for examining a patient's body cavity includes an endoscope having a distal end, a proximal end and a number of lumens therein. One or more distal gas ports are disposed at or adjacent the distal end of the endoscope and one or more prox... | 02/26/2008 |
