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| Number | Title | Issue Date |
| 8190252 | Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes An embodiment of a system includes a power source and at least two electrode assembles. The power source that an output current that alternates between a maximum current value and a minimum current value; a pair of electrode assemblies. Each electrode assembly is co... | 05/29/2012 |
| 8180444 | Enhanced PhotoDynamic Therapy with immune system assist A photodynamic therapy (PDT) method to treat primary sites of hyperproliferative tissue and induce long term, tumor specific immunity for regression and eradication of distant metastases is disclosed. The improved treatment regimen comprises the partial or fractiona... | 05/15/2012 |
| 8175697 | Catheter for insertion into the human body A catheter for insertion into the human body and which includes one or more optionally scanning ultrasonic transducers (7) and a needle guide, which can be operated from the outside and used for collecting tissue samples from the human body. The catheter incl... | 05/08/2012 |
| 8170657 | Delivery catheters for light activated agents A delivery catheter for delivery, then photo-activation of photo sensitive material has a photo-sensitive substance-delivery part and an activation part. The catheter delivers substances such as biomaterials to a target site, followed by illumination of the target u... | 05/01/2012 |
| 8155738 | Composition and device structure for iontophoresis Device structure 100 for iontophoresis provides electrode 101 and electrically conductive layer 102. Electrically conductive layer 102 contains active ingredient D and basic water swelling methacrylate copolymer P1 and/or acidic wa... | 04/10/2012 |
| 8155737 | Pharmacokinetics of iontophoretic sumatriptan administration Improved pharmacokinetic profiles for the iontophoretic delivery of sumatriptan are described. ... | 04/10/2012 |
| 8126544 | Combination iontophoresis and detoxifying device and methods for use A device for imparting a combination of therapies to a user's body or body parts has a first battery-powered array submerged into a liquid contained in a first reservoir and a second battery-powered array submerged into a liquid contained in a second reservoir. Each... | 02/28/2012 |
| 8126543 | Device for electrochemotherapy A device for electrochemotherapy comprises an electric micro- or nano-capacitor which can be injected in the blood circulation of a human or animal body, including a pyroelectric or piezoelectric layer which can be excited from the outside of the human or animal bod... | 02/28/2012 |
| 8116860 | Transdermal porator and patch system and method for using same A transdermal permeant delivery system for delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substrate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the ... | 02/14/2012 |
| 8108040 | Method and apparatus for delivery of therapeutic agents Method and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent (30) through an orifice to the patient, a plurality of... | 01/31/2012 |
| 8103339 | Nerve stimulator with suction capability A device for use in a removing fluids and debris from a surgical wound and for location of nerves adjacent to the surgical wound comprises a hollow electrically conductive tube which has a lumen extending from the distal end thereof to the proximal end thereof. Open... | 01/24/2012 |
| 8099162 | Ocular iontophoresis device The invention relates to a device of ocular iontophoresis for delivering active substances, comprising a reservoir having an outer wall and a hollow body at least partly delimited by the outer wall, wherein the hollow body is capable of receiving an electrical condu... | 01/17/2012 |
| 8095213 | Transdermal patch A transdermal patch can include a drug source, a porator, and an energy storage device on-board the patch. Conductive contact terminals can extend from the energy storage device for connection to an external source of power. The porator operates free of any concurre... | 01/10/2012 |
| 8050752 | Method of treating lumens, cavities, and tissues of the body with an ultrasound delivered liquid The present invention relates to a method of treating lumens, cavities, and tissues of the body with a liquid delivered with the use of ultrasound. Delivering a liquid with the use of ultrasound may be accomplished by utilizing a device comprising an ultrasound tran... | 11/01/2011 |
| 8041422 | In-body information acquiring apparatus and power-supply circuit An in-body information acquiring apparatus includes a function executing unit that realizes a predetermined function inside a body of a patient. A power-supply circuit includes a power unit that includes a cell and that outputs a first current and a first voltage; a... | 10/18/2011 |
| 8041421 | Transdermal delivery system for polynucleotides A system for intradermal or transdermal delivery of oligonucleotides or polynucleotides and methods of use thereof employ an apparatus that generates micro-channels in the skin of a subject in conjunction with a pharmaceutical composition comprising an oligonucleoti... | 10/18/2011 |
| 8036738 | Iontophoretic transdermal drug delivery system based on conductive polyaniline membrane An iontophoretic transdermal drug delivery system that utilizes a porous conductive polyaniline membrane as one of two electrodes, with both electrodes in contact with an aqueous solution of the ingredient in ionic and nonionic form, and the membrane additionally in... | 10/11/2011 |
| 8027718 | Regional anesthetic A method and apparatus are disclosed for anesthetizing a region of a patient's body. The method includes identifying a target nerve which, upon activation, anesthetizes a region of a patient's body including a surgical site. The target nerve is located and an active... | 09/27/2011 |
| 8024033 | Iontophoretic electrode An electrode for an iontophoretic drug delivery system includes a retainer having a malleable characteristic. The retainer and a conductor are connected to a platform. The conductor and a dose controller are electrically coupled to the iontophoretic drug delivery sy... | 09/20/2011 |
| 8019412 | Apparatus for facilitating transdermal delivery of therapeutic substances and method of transdermally delivering therapeutic substances An apparatus (40) is disclosed for facilitating transdermal delivery of therapeutic substances. The apparatus (40) comprises means (44) for producing an electromagnetic field, control means (26, 34) arranged to control said field producin... | 09/13/2011 |
| 8014855 | Feedback control device for transcutaneous drug delivery and uses therefor Provided herein is a device for altering a biological membrane in an individual comprising a means for delivering energy to the surface of the biological membrane, a means for monitoring a physiological state of the biological membrane during delivery of said energy... | 09/06/2011 |
| 8014854 | Method and device for treating abnormal tissue growth with electrical therapy This invention relates generally to the electrical treatment of malignant tumors and neoplasms by applying a voltage to affected tissue. Devices and various adaptations therein are described for use in electrical therapy. Additionally, various chemotherapeutic agent... | 09/06/2011 |
| 8010188 | Drug injecting device There is provided a drug injecting device including a drug feeding unit (110) feeding a drug (111a) to a surface of an object (200), an ultrasonic oscillating unit (120) oscillating an amplitude-modulated ultrasonic wave group in w... | 08/30/2011 |
| 7996077 | Iontophoresis apparatus and method An iontophoresis apparatus and method is disclosed that is suited to deliver a plurality of treatment methods such as, but not limited to, body site conductivity enhancement followed by low voltage iontophoresis. ... | 08/09/2011 |
| 7991464 | Transdermal therapeutic system The present invention relates to a transdermal therapeutic system for the controllable release of an active ingredient, particularly a substance promoting wound healing, to a chronic wound or for chemotherapy, with at least one waveguide, wherein the active ingredie... | 08/02/2011 |
| 7979117 | Device and method for controlled delivery of active substance into the skin An apparatus for dermal treatment of an active substance having certain physical properties having a flexible, wearable patch conformable to the contour of a skin surface and having: a first electrode adapted to communicate the active substance into the skin by appl... | 07/12/2011 |
| 7979118 | Low frequency generation poultice A low frequency generating poultice includes a poultice sheet; a contact fabric that is adhered to a non-medicated surface of the poultice sheet; a release sheet that is attached to a medicated surface of the poultice sheet; a low frequency oscillator; a pair of lef... | 07/12/2011 |
| 7945320 | Iontophoretic drug delivery system The iontophoretic drug delivery system includes electrodes controlled by a microprocessor controller to drive charged molecules contained in a drug reservoir through the skin into the issues of a patient. The iontophoretic drug delivery system further includes an an... | 05/17/2011 |
| 7945321 | Method and apparatus for skin absorption enhancement and transdermal drug delivery A system for enhancing absorption of a substance to be provided on a region of a patient's skin, includes a probe configured to provide the substance to the region of the patient's skin, the probe including a flexible tape with a plurality of cavities, and with an e... | 05/17/2011 |
| 7945319 | Methods of delivering a drug using a medical device with a coating comprising a self-assembled molecular structure A method for local delivery of a drug is provided. The method comprises acts of: (a) implanting a medical device including a drug-containing coating in a patient for the delivery of the drug, wherein the coating comprises a drug and a polymer; and (b) applying an el... | 05/17/2011 |
| 7941211 | Preloading with macular pigment to improve photodynamic treatment of retinal vascular disorders Pre-treatment using a xanthin carotenoid (preferably 3R,3′R-zeaxanthin) can improve the benefits and efficacy of photodynamic therapy (PDT), which uses a light-activated drug (such as verteporfin) in patients who suffer from unwanted retinal blood vessel growth, i... | 05/10/2011 |
| 7941212 | Method of delivering a drug using a medical device with a coating comprising a self-assembled molecular structure A method for local delivery of a drug is provided. The method comprises the acts of (a) implanting a medical device carrying a drug-containing coating in a patient for the sustained local delivery of the drug, wherein at least a portion of the coating is transformed... | 05/10/2011 |
| 7937142 | Irritation-reducing ocular iontophoresis device The invention provides an ocular iontophoresis device for delivering medication, the device comprising a medication reservoir suitable for being positioned on the eye, at least one medication in solution in the reservoir, an active electrode disposed in the reservoi... | 05/03/2011 |
| 7937141 | Device for iontophoresis A device for iontophoresis that reduces irritation at the beginning of energization and efficiently supplies an amount of current required for drug administration in a predetermined length of time, is provided. With the device for iontophoresis, the oscillation freq... | 05/03/2011 |
| 7933647 | Methods of increasing lipolysis Methods for increasing lipolysis in a cell are described herein. Such methods comprise the application of an electrical current to a cell. In an embodiment, the application of the electrical current does not substantially alter the viability of such cell and/or pres... | 04/26/2011 |
| 7917205 | Iontophoresis-based medical device An iontophoresis-based medical device includes a positive electrode section, a negative electrode section, a power source supplying an electric current to the positive electrode section and negative electrode section and a controller controlling the current value an... | 03/29/2011 |
| 7912538 | Controlled release transdermal drug delivery Provided herein is a device for controlling the release of a substance at a site of interest in a biological membrane comprising a means of monitoring a physiological state at the site of interest; and a means of releasing a variable amount of the substance to the s... | 03/22/2011 |
| 7904146 | Transdermal systems for the delivery of ionic agents directly to open wounds and surgically repaired incisions A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a d... | 03/08/2011 |
| 7890164 | Iontophoresis device An shaped iontophoresis device is capable of permeating an active agent (e.g., a drug solution) into an oral cavity, a skin cancer, or the like by iontophoresis in a pinpoint manner. A catheter-type iontophoresis device includes a small working electrode assembly an... | 02/15/2011 |
| 7885708 | Iontophoresis device A device for iontophoresis. A first battery-powered array is submerged into a liquid contained in a first reservoir and a second battery-powered array is submerged into a liquid contained in a second reservoir. Each array has one or more degradable electrodes that r... | 02/08/2011 |
