"Flight by machines heavier than air is unpractical and insignificant, if not utterly impossible."
Simon Newcomb, astronomer ; Said in 1902, less than two years before the first flight at Kitty Hawk
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| Number | Title | Issue Date |
| 7384412 | Endovascular system for the treatment of stenoses of the carotid and catheter for this system A catheter, in particular for endovascular applications, including a long and flexible, hollow, tubular body having an insertion end and a connection end intended to remain outside the body. The catheter includes in the insertion end at least two elements which are ... | 06/10/2008 |
| 7364562 | Anti-clotting apparatus and methods for fluid handling system A method for maintaining clear passageways in an extracorporeal blood flow system. The method comprises intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. Also disclosed is an extracorporeal blood flow ... | 04/29/2008 |
| 7338467 | Device for minimally invasive intravascular aortic valve extraction A perfusion catheter includes at least one perfusion channel and at least two dilation units disposed at a distance from each other at the distal catheter region in the longitudinal extension of the catheter. Both of the at least two dilation units are projected thr... | 03/04/2008 |
| 7300662 | Drug/drug delivery systems for the prevention and treatment of vascular disease A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f... | 11/27/2007 |
| 7267686 | Implantable prosthetic valve A prosthetic valve for implantation within a fluid conducting lumen within a body includes an elongate generally cylindrical radially collapsible valve body scaffold defining a fluid passageway therethrough for retentive positioning within the lumen. A radially coll... | 09/11/2007 |
| 7255687 | Systems and methods for luminal access A luminal access system comprises an evertable, lubricious sleeve, a pusher tube, and optionally a lumen tube. The evertable, lubricious sleeve is attached to a non-evertable sheath which is coaxially received over the pusher tube. A distal portion of the evertable ... | 08/14/2007 |
| 7244242 | Valve treatment catheter and methods The invention provides a catheter for insertion into a biological passage which contains a first flowing fluid, the catheter including a tubular member having a proximal end and a distal end; a fluid delivery lumen contained within the tubular member; an inflatable ... | 07/17/2007 |
| 7229473 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 06/12/2007 |
| 7223286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/29/2007 |
| 7220269 | Thrombectomy catheter system with occluder and method of using same A thrombectomy catheter system with occluder and method of using same for removal of tissue, such as thrombus and the like, from a vessel in the body. Multiple catheters and an occluder-bearing guidewire tube at a thrombus site provide for expandable deployment of a... | 05/22/2007 |
| 7217286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/15/2007 |
| 7182745 | Retaining stent A medical device for use within a body of a patient includes at least two retention members located at a first end of an elongated section of the medical device. The retention members are adapted to limit longitudinal movement of the elongated section when the medic... | 02/27/2007 |
| 7179250 | Methods and apparatus for treating body tissues and bodily fluid vessels According to a method of occluding a bodily fluid vessel, a catheter is provided that has a first passage. The first passage has an occlusion element housed therein. The catheter is positioned in the vessel, and the occlusion element is moved out of the passage and ... | 02/20/2007 |
| 7156872 | Implantable valve system An implantable valve having a valve element or leaflet and a base that is attachable to a vessel wall using a connector such as a screw, pin or a staple. The valve can be implanted using a catheter to position the valve in a desired location and drive the connector ... | 01/02/2007 |
| 7131986 | Catheter having exchangeable balloon An intravascular balloon catheter comprises a tubular catheter body having a balloon structure removably mounted over the catheter body. The catheter body has a guidewire lumen, and the catheter body may be left in place within a patient's vasculature while the ball... | 11/07/2006 |
| 7108677 | Embolization protection system for vascular procedures Apparatus and methods are described for effective removal of emboli or harmful fluids during vascular procedures, such as angiography, balloon angioplasty, stent deployment, laser angioplasty, atherectomy, intravascular ultrasonography and other therapeutic and diag... | 09/19/2006 |
| 7081131 | Artificial valve Method and apparatus implementing and using techniques for controlling flow in a body lumen, including use of an implantable medical device. The device includes a membrane implantable in a body lumen and invertibly deformable between a first position and a second po... | 07/25/2006 |
| 7066905 | Method and apparatus for accurate positioning of a dual balloon catheter Embodiments of the present invention are directed to a method and apparatus for accurate positioning of a dual balloon catheter. In one embodiment of the present invention, a first balloon provides an anchoring point. In one embodiment, the first balloon has protrus... | 06/27/2006 |
| 7063714 | Apparatus and methods for treating stroke and controlling cerebral flow characteristics Apparatus and methods for treatment of stroke are provided. In a preferred embodiment, the present invention disposes at least one catheter having a distal occlusive member in either the common carotid artery (CCA) or both the vertebral artery (VA) and the CCA on th... | 06/20/2006 |
| 7022104 | Facilitated balloon catheter exchange A balloon catheter comprises a catheter body, a balloon at a distal end of the catheter body, and a guidewire tube within the balloon and separate from the catheter body. A catheter may be introduced over a guidewire by passing the guidewire through a guidewire lume... | 04/04/2006 |
| 7007698 | Body lumen closure Method and apparatus implementing and using techniques for body lumen closure, including use of an implantable medical closure device. The device includes a flexible strand defining an arcuate form. The strand is deformable upon implantation from a large cross-secti... | 03/07/2006 |
| 6960203 | Thermal ablation with deployable cage A medical device is provided and includes a thermal ablation catheter and a deployable cage assembly for use in thermal ablation therapy. The deployable cage assembly includes a plurality of arms, each of which has a pair of opposed ends attached to the thermal abla... | 11/01/2005 |
| 6958059 | Methods and apparatuses for drug delivery to an intravascular occlusion A method for delivering a drug to the site of an intravascular occlusion. A guidewire having a balloon at one end is advanced across the occlusion using a guide catheter, and the balloon is inflated distal to the occlusion to occlude the blood vessel. An aspiration ... | 10/25/2005 |
| 6949114 | Systems, methods, and compositions for achieving closure of vascular puncture sites Systems and methods convey a closure material into a catheter to seal a puncture site in a blood vessel. The closure material comprises a mixture of first and second components which, upon mixing, undergo a reaction to form a solid closure material composition. The ... | 09/27/2005 |
| 6945957 | Valve treatment catheter and methods The invention provides a catheter for insertion into a biological passage which contains a first flowing fluid, the catheter including a tubular member having a proximal end and a distal end; a fluid delivery lumen contained within the tubular member; an inflatable ... | 09/20/2005 |
| 6932792 | Antegrade cardioplegia catheter and method A cardioplegia catheter is configured to extend into the ascending aorta with a proximal portion of the shaft extending into a left chamber of the heart through a aortic valve and out of the heart through a penetration in a wall thereof. The cardioplegia catheter ha... | 08/23/2005 |
| 6929633 | Apparatus and methods for clot dissolution Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, agitate the clot and agent, and aspirate broken-up clot from the blood vessel. A flow resistor in the catheter provides for infusion and/or aspiration to... | 08/16/2005 |
| 6902535 | Guide-wire mounted balloon modulation device and methods of use An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion of a guide wire catheter. A preferred embodiment apparatus features a mechanism for controllably gripping and releasing the open, proximal end of a tubular guide wire, a ... | 06/07/2005 |
| 6736790 | Method and system for selective or isolated integrate cerebral perfusion and cooling Patients having diminished circulation in the cerebral vasculature as a result of cardiac arrest or from other causes are treated by flowing an oxygenated medium through an arterial access site into the cerebral vasculature and collecting the medium through an acces... | 05/18/2004 |
| 6689097 | Flow-by channel catheter and method of use A vascular catheter assembly includes an over-the-wire stent deployment catheter and a flow-by-channel assembly. The stent deployment catheter is positioned just below the occluded artery in accordance with standard procedures. The flow-by-channel then sh... | 02/10/2004 |
| 6663613 | System and methods for clot dissolution Clot disruption and dissolution are achieved using a catheter having both an agitator and the ability to deliver a thrombolytic agent. The catheter is introduced to a target region with a blood vessel and the agitator manipulated to engage and disrupt a r... | 12/16/2003 |
| 6595941 | Methods for external treatment of blood Vascular access systems, devices and methods for facilitating repeated access to a blood vessel. These systems, devices and methods can be used in external blood treatment, such as dialysis, and in intra-venous administration of medicines, such as heparin... | 07/22/2003 |
| 6589264 | Aortic occluder with associated filter and methods of use during cardiac surgery A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the ... | 07/08/2003 |
| 6582396 | Puncture resistant balloon for use in carotid artery procedures and methods of use Methods and apparatus are provided for removing emboli during an angioplasty, stenting, or surgical procedure comprising apparatus for occluding the external carotid artery to prevent reversal of flow into the internal carotid artery during carotid stenti... | 06/24/2003 |
| 6569148 | Methods for emboli containment A multi-catheter emboli containment system is disclosed which is adapted to provide at least one pair of optimized paths for irrigation and aspiration fluid flow. Through careful design of the cross-sectional area of these paths, the present system is abl... | 05/27/2003 |
| 6506180 | Passive perfusion sleeve/placement catheter assembly A passive perfusion sleeve/placement catheter assembly for performing coronary angioplasty allows prolonged dilatations without blocking blood flow. The perfusion sleeve comprise an elongated shaft with a distally mounted composite balloon including a sem... | 01/14/2003 |
| 6461327 | Atrial isolator and method of use An atrial isolator comprising two tubular members, two lumens, drainage ports, and expandable occluders. The expandable occluders are adapted to engage an opening of the superior vena cava into the right atrium or the inferior vena cava and right tricuspi... | 10/08/2002 |
| 6454790 | Treatment for Barrett's syndrome An apparatus and method for treating Barrett's tissue by removal of the mucosa through PhotoDynamic Therapy(PDT) is provided. A viscous gel is the medium used to carry the photosensitizer to the treatment site and allow sufficient time to transfer to the ... | 09/24/2002 |
| 6398773 | Aspiration system and method Aspiration catheters and methods for the treatment of an occlusion in a blood vessel. These catheters and methods are especially useful in the removal of occlusions from saphenous vein grafts, the coronary and carotid arteries, arteries above the aortic a... | 06/04/2002 |
| 6306116 | Method and apparatus for pressurizing the right atrium or right ventricle to assist cardiac function during beating heart surgery A method and apparatus for pressurizing the right atrium or right ventricle of a beating heart during surgery to assist cardiac function. The apparatus has an intake tube for insertion in the inferior or superior vena cava, a return tube for insertion in ... | 10/23/2001 |