William F. Semple, a dentist, was awarded the first US Patent on chewing gum in 1869. His recipe contained powdered chalk.
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| Number | Title | Issue Date |
| 8187206 | Guide wire A guide wire includes a member with a core wire. The guide wire may have a marker-forming layer which partly encircles the outer surface of the member and differs in color from the member, and a coating layer which covers the marker-forming layer and the member at l... | 05/29/2012 |
| 8187207 | Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible ra... | 05/29/2012 |
| 8182432 | Corewire design and construction for medical devices A guidewire for use in ear, nose and throat procedures may include an elongate core wire having a proximal region and a distal region. The distal region of the core wire may include a flattened portion adapted to provide preferential flexure along at least one axis ... | 05/22/2012 |
| 8172774 | Guide wire A guide wire includes a wire body having a plate-shaped reshapeable section at a distal part thereof, wherein the reshapeable section is provided along the longitudinal direction thereof with a plurality of bent parts bent in opposite directions. At least one of the... | 05/08/2012 |
| 8167821 | Multiple diameter guidewire A guidewire can include a shaft or core wire that has a distal section configured for access to a vascular treatment site and a proximal section configured for intervention at a vascular treatment site. At least a portion of the distal section of the shaft or core w... | 05/01/2012 |
| 8167822 | Splittable wire guide A splittable wire guide having a plurality of separable elongate components that may be separated or otherwise re-positioned relative to each other so as to alter the physical properties of the wire guide or to form a plurality of separate wire guide members. ... | 05/01/2012 |
| 8162855 | Medical guide wire and process for production thereof A medical guide wire (1) is made in which at least a fluororesin coating layer (13) is formed on the surface of a metal wire (11), wherein particulate matter is present in the fluororesin coating layer (13), and the fluororesin coating la... | 04/24/2012 |
| 8162856 | Sensor catheter having reduced cross-talk wiring arrangements Improved wiring arrangements for sensor catheters are provided to reduce wire-to-wire cross-talk wherein wires connecting the sensor of the sensor catheter to a processing unit are divided into a plurality of wire bundles contained within respective sheaths, with th... | 04/24/2012 |
| 8157751 | Coil member for a medical device A coil for use in a medical device. The coil includes a plurality of coil windings or turns, wherein adjacent coil windings are connected together at a plurality of discrete connection locations to increase the torsional rigidity and torque transmitting properties o... | 04/17/2012 |
| 8152742 | Crossing guide wire with corrugated shaping ribbon A medical device with a corrugated shaping ribbon is provided. The corrugated shaping ribbon for the medical device, which may be provided in the form of a guide wire or catheter, specifically a crossing guide wire or catheter, provides a mechanism by which energy c... | 04/10/2012 |
| 8147427 | Guidewires twist releasing device To provide a means capable easily releasing twist of two or more guidewires passed through a guiding catheter without pulling out the guidewires. A twist releasing apparatus has a shaft, a first tube formed at the tip of the shaft and has a first lumen through which... | 04/03/2012 |
| 8142367 | Method and apparatus for deflecting a screw-in lead A deflectable stylet system optimized for use in conjunction with a lead of the type having a fixation helix that is screwed into body tissue by rotation of the lead's connector pin is disclosed. The system includes an attachment that is rotatable and longitudinally... | 03/27/2012 |
| 8137291 | Wire guide having distal coupling tip A coupling wire guide generally includes a main body defined by a first wire wound around a safety wire. A first loop is defined by an enlarged revolution of the first wire within a distal portion of the main body. The first loop is sized to receive a previously int... | 03/20/2012 |
| 8137292 | Elongated medical device for intracorporal use Alternative designs, materials and manufacturing methods for medical devices. Some embodiments disclosed deal with attachment of an elongated structure, such as a wire or ribbon, or a tubular member, such as a coil, to an elongated member in an elongated device. For... | 03/20/2012 |
| 8137293 | Guidewires including a porous nickel-titanium alloy Medical devices and methods for making and using the same are disclosed. An example medical device may include a guidewire. The guidewire may include an elongate shaft. The shaft may include a porous metal alloy. The porous metal alloy may be arranged so that the po... | 03/20/2012 |
| 8133190 | Weldable wire guide with distal coupling tip A coupling wire guide structured to be slidably coupled to a previously introduced wire guide. The coupling wire guide includes a main body and a coupling tip, the coupling tip having first and second sections. The first section is connected to the main body, while ... | 03/13/2012 |
| 8128580 | Guide wire A guide wire includes a wire body having an elongate reshapeable section at its distal part. The guide wire may include a surface of the reshapeable section being provided with a plurality of grooves extending in a direction different from the longitudinal direction... | 03/06/2012 |
| 8128579 | Guidewires with improved fatigue life and methods of making the same A medical device, such as a medical guidewire, having a portion including an inner zone of material and an outer peripheral zone of material surrounding the inner zone of material. The inner zone of material has a first coefficient of thermal expansion and the outer... | 03/06/2012 |
| 8123703 | Steerable access sheath and methods of use The present invention provides devices, systems, methods and kits for endoscopically accessing a body cavity and providing a directed pathway toward a target tissue within the cavity. The directed pathway is provided by an access sheath which is positioned in a desi... | 02/28/2012 |
| 8123702 | Composite guide wire with drawn and filled tube construction The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation harde... | 02/28/2012 |
| 8114031 | Facilitation of antegrade insertion of a guidewire into the superficial femoral artery A guidewire for antegrade guidance of vascular interventions of a lower limb artery via a common femoral artery into a superficial femoral artery of a human patient. When in unloaded condition, the guidewire has, at its distal end, a rounded or floppy tip (4)... | 02/14/2012 |
| 8114032 | Systems and methods for medical device advancement and rotation A system for moving an elongate medical device has at least one drive element for engaging and moving an elongate medical device. Various embodiments provide for moving the separate inner and outer elements of a telescoping medical device. Some systems also provide ... | 02/14/2012 |
| 8109889 | Bending resistant male connector for a guide wire During use there is a risk that a male connector for a guide wire is bent. With the present male connector (1) more material with high modulus of elasticity can be provided inside the male connector (1), which makes the male connector (1) more b... | 02/07/2012 |
| 8109887 | Guide wire A method of making a guide wire involves butting a connection end face at a proximal end of a first wire against a connection end face at a distal end of a second wire while applying voltage and a pressing force to weld together the first and second wires at a welde... | 02/07/2012 |
| 8109888 | Medical guide wire A medical guide wire includes a flexible long core. A core elongated component is disposed to extend forwards from the core, and has a tapered shape. A helical coil is disposed about the core elongated component, secured by attachment of a coil distal end and a coil... | 02/07/2012 |
| 8105246 | Elongate medical device having enhanced torque and methods thereof An elongate medical device such as a guidewire, that may comprise a first elongate member having a proximal end, a distal end and a lumen there between, a second elongate member having a proximal end and a distal end, the second elongate member at least partially di... | 01/31/2012 |
| 8100838 | Variable stiffness guidewire systems A variable-stiffness guidewire system which comprises an elongated flexible guidewire. The guidewire has a body and a guidewire head coupled to the body. The guidewire head is slidably moveable with respect to a guidewire collar of the body to adjust a stiffness of ... | 01/24/2012 |
| 8100837 | Superelastic guidewire with locally altered properties A guidewire formed at least in part of a superelastic member with a section having one or more altered properties including physical and mechanical properties. Preferably, the section of altered property has reduced superelasticity with respect to the remainder of t... | 01/24/2012 |
| 8096959 | Trans-septal catheter with retention mechanism A trans-septal guide catheter for providing access through the septum separating a first heart chamber from a second heart chamber that includes an elongated guide catheter body extending between guide catheter proximal and distal ends. A distal segment of the guide... | 01/17/2012 |
| 8092395 | Guide wire for use in re-canalising a vascular occlusion in a human or animal subject A guidewire (1) for re-canalizing a vascular occlusion comprises a core wire (5) which terminates at its distal end (4) in a terminal member (7) for opening the occlusion. A helical coil sleeve (10) extends around the core wire ( | 01/10/2012 |
| 8083689 | Distal protection guidewire with nitinol core A guidewire having a proximal section, a distal section, and a transition section is disclosed. In one exemplary embodiment of the present invention, the proximal section may be formed of a relatively stiff, inelastic material, whereas the distal section may be form... | 12/27/2011 |
| 8083690 | Convertible guidewire system and methods A guidewire converter for use in intravascular procedures along with a guidewire. The guidewire converter includes an elongate tubular structure defining a lumen having an inner diameter and a first outer diameter. The inner diameter of the lumen is sized to receive... | 12/27/2011 |
| 8075497 | Wire guide having distal coupling tip A coupling wire guide structured to be slidably coupled to a previously introduced wire guide during intracorporeal procedures. The coupling wire guide includes a main body and a tip portion, the tip portion having first, second and third sections. The first section... | 12/13/2011 |
| 8070694 | Fiber based medical devices and aspiration catheters Systems for less invasive medical procedures comprise a filter device mounted on an integrated guiding structure and an aspiration catheter. These components can be used together or separately, and the system can be used with other medical devices that are designed ... | 12/06/2011 |
| 8070693 | Articulating steerable wire guide A steerable wire guide comprises first and second members interconnected to form a unitary composite structure. The members slide relative to each other such that the leading portion of the composite structure bends in a first or second direction. The composite stru... | 12/06/2011 |
| 8057405 | Composite guidewire with drawn and filled tube construction The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation harde... | 11/15/2011 |
| 8052620 | Guide wire and stent A guide wire includes a distal core member made of a ferrous alloy which has shape memory properties and superelasticity. The ferrous alloy preferably includes substantially two phases, and has a difference of 100° C. or less between an Af point and an Ms point in ... | 11/08/2011 |
| 8048004 | Medical device for navigation through anatomy and method of making same Medical devices for navigation through anatomy, including guidewires, which may have a core wire, a slotted tubular member, or both. Embodiments may have coils, including non-circular cross-section edge-wound marker coils, extended coil tips, and soldered or glued m... | 11/01/2011 |
| 8043232 | High performance wire guide A high performance wire guide is disclosed, having a core wire and an outer member disposed about the core wire for enhanced torque transmission along a longitudinal length of the core wire. The outer member may be an outer coil wrapped around the core wire in an in... | 10/25/2011 |
| 8038628 | Torque device for a sensor guide wire The invention relates to a torque device for a sensor guide wire having a sensor provided at a distal portion and a male connector provided at the proximal end, which torque device comprises a grip body and a cap adapted to be joined to the grip body, and a number o... | 10/18/2011 |