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| Number | Title | Issue Date |
| 7942827 | Minimally invasive allergy testing system An allergy testing system includes encapsulated allergens, a microneedle array, and an activation system coupled to the microneedle array and the encapsulated allergens such that the encapsulated allergens are moved into contact with a subject as the microneedle arr... | 05/17/2011 |
| 7896816 | Skin test device Skin test device has a film backing. The film backing is made of silicone, and is marked off into divisions by grooves. The divisions each have a different sample containing a suspected allergen. The film backing has a see-through feature and the condition of the sk... | 03/01/2011 |
| 7798976 | Epicutaneous test plaster An epicutaneous test plaster, which is intended for removable adhesion to a skin portion of a person subjected to testing, has a flexible carrier (10) with a medical adhesive layer (12) and a number of test chambers (31). The test chambers conta... | 09/21/2010 |
| 7351209 | Apparatus for inspecting allergic reaction An apparatus for inspecting an allergic reaction projects laser light onto an object having a bloodstreams and receives, using a light sensor, light rays scattered by blood cells at the surface of the object. Based on signals output from the light sensor, the appara... | 04/01/2008 |
| 7316665 | Method and device for the delivery of a substance including a covering An abrasion device and method for delivery of substances into the skin using a microabrader for delivering a substance into the skin are disclosed. An abrasion device with a cover is also disclosed. Such devices and methods can be effectively used to deliver bioacti... | 01/08/2008 |
| 7202392 | In vivo screening array The invention features methods of evaluating the effect of a plurality of different treatments or compounds on a tissue. The method includes providing a tissue from an animal; contacting the tissue with a plurality of treatment, forming on the tissue an array of a p... | 04/10/2007 |
| 7186046 | Binary applicator An applicator including at least one tube with at least one plug of a liquid or a powder inside the tube. At least a first substance is contained in an inside space of the tube, with the space defined at a first end by the liquid or powder plug. The plug is arranged... | 03/06/2007 |
| 7182747 | Solid solution perforator for drug delivery and other applications A solid drug solution perforator (SSP) system and an associated drug reservoir are provided for delivering therapeutic, prophylactic and/or cosmetic compounds, for nutrient delivery and for drug targeting. For drug delivery, the SSP system includes an active drug in... | 02/27/2007 |
| 7083592 | Device and method for delivering withdrawing a substance through the skin An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface... | 08/01/2006 |
| 7027478 | Microneedle array systems The present invention relates to systems of microneedle arrays to align and form optical components. Active components such as lasers are combined with optical fibers. Microneedles are fabricated using techniques such as laser drilled Kapton, and combined with optic... | 04/11/2006 |
| 6945964 | Hypodermic needle A medical needle adapted for conducting fluid comprising a generally cylindrical tube having a central longitudinal axis, a first end and a second pointed end adapted for penetration into a bodily cavity of a subject, wherein the pointed end includes a plurality of ... | 09/20/2005 |
| 6756032 | Method to enhance and/or prolong the effects of a primary challenge to a responsive system with a secondary challenge The present invention relates to a method comprising subjecting a test site of a responsive system to a primary challenge; subjecting the same test site to a secondary challenge, wherein the secondary challenge is designed to enhance and/or prolong a response of the... | 06/29/2004 |
| 6738652 | Classification and screening of test subjects according to optical thickness of skin A method for classifying live subjects according to optical thickness of the skin is based on noninvasive, near-infrared reflectance measurements on skin tissue. An indicator of skin optical thickness is derived through analysis of the water, fat, and protein marker... | 05/18/2004 |
| 6629932 | Allergen and irritant measuring device A device is described that can be easily used to warn an asthmatic or allergen reacting patient of irritant levels which may trigger an asthma or allergy attack for that person. The device continually monitors and records irritants in the air, and when th... | 10/07/2003 |
| 6554777 | Multi-site skin-test system and method A multi-site skin-test system including a reservoir tray and strips of interconnected reservoir caps inserted into upper portions of the reservoirs. The caps each include a generally conically shaped hole. Connection members connect the caps of a strip to... | 04/29/2003 |
| 6488622 | Method and aid for the early recognition of sunburn A method for the early detection of sunburn is provided in which the reflection spectrum of the irradiated skin is considered. A color change made perceptible to the human eye is obtained from the specific absorption and reflection behavior. The change is... | 12/03/2002 |
| 6478749 | Diagnostic kit for skin tests, and method A skin test for detecting the immune status with respect to the transforming virus proteins E6 and E7 of human papilloma viruses is provided. The skin test comprises a diagnosis kit containing an effective amount of the protein E6 and/or E7 or at least an... | 11/12/2002 |
| 6475160 | Skin testing device A skin testing device having a housing that supports a wheel. The wheel has a plurality of pointed tines for introducing a freeze dried allergen solution to a patient's skin. The pointed tines are located on an allergen plate that has radial grooves for r... | 11/05/2002 |
| 6447482 | Injector An injector serving for injection of an injection fluid is described. The injector includes a housing with a contact face for during injection supporting on the skin of a person. The injection fluid is placed in a chamber in the housing which furthermore ... | 09/10/2002 |
| 6410333 | Assessment of human skin damage following exposure to harmful agents The present invention relates to the assessment of ultraviolet radiation UV effects on sunscreen-treated and non-treated human skin using a more sensitive technique.... | 06/25/2002 |
| 6322520 | Allergy testing apparatus Allergy testing apparatus (10) includes a housing (18) with opposed parallel sidewalls (22, 24) and a pair of pressure plates (30, 32) located therebetween. The surfaces between each sidewall and adjacent pressure plate are configured into shallow opening... | 11/27/2001 |
| 6258041 | Strip tray allergy testing apparatus An allergen testing pick for receipt in the open top end of a vial of allergen and including a neck for close fit with the top end of such vial. The pick includes a stem depending downwardly from such neck and is formed with a plurality of sharp tines. A ... | 07/10/2001 |
| 6221027 | Modular allergy testing apparatus An allergen testing pick for receipt in the open top end of a vial of allergen and including a neck for close fit with the top end of such vial. The pick includes a stem depending downwardly from such neck and is formed with a plurality of sharp tines. A ... | 04/24/2001 |
| 6206838 | Autoloader and skin testing system There is provided an autoloader apparatus and skin testing system for rapidly loading a multi-headed applicator used for epicutaneous application of biological testing agents, while at the same time, effectively inhibiting cross contamination of testing a... | 03/27/2001 |
| 6188470 | Bioenergetic data collection apparatus A Bioenergetic Data Collection Apparatus utilizing a modified oximeter (1) to collect signals characteristic of blood flow in terminal tissue, such as a finger tip (12). A processing means (7) in signal connection with the modified oximeter (1) receives a... | 02/13/2001 |
| 6142954 | Epicutaneous test plaster A patch test plaster having at least one active substance receptacle arranged on a backing film, having a highly elastic backing film which is made of polymeric material, is impermeable to liquid water but permeable to water vapour, and is releasibly conn... | 11/07/2000 |
| 6095988 | Autoloader and skin testing system There is provided an autoloader apparatus and skin testing system for rapidly loading a multi-headed applicator used for epicutaneous application of biological testing agents, while at the same time, effectively inhibiting cross contamination of testing a... | 08/01/2000 |
| 6083196 | Device for enhancing transdermal agent flux A device (3) comprising a sheet member (6) having a plurality of microprotrusions (4) for penetrating the skin and a substantially incompressible agent reservoir housing (15) contacting and extending across the sheet member (6) for transmitting a hold-dow... | 07/04/2000 |
| 6077229 | Allergy testing apparatus An allergen testing pick for receipt in the open top end of a vial of allergen and including a neck for close fit with the top end of such vial. The pick includes a stem depending downwardly from such neck and is formed with a plurality of sharp tines. A ... | 06/20/2000 |
| 6024706 | Quantitative skin allergic test device The present invention relates to an improved quantitative skin allergic test device, which has a finger grip to be held by fingers and multiple legs longitudinally attached to the finger grip. Each leg has a cover having a sealing plug portion adaptful fo... | 02/15/2000 |
| 6017301 | Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions The present invention relates to improved methods for making and using bioadhesive, bioresorbable, anti-adhesion compositions made of intermacromolecular complexes of carboxyl-containing polysaccharides and polyethers, and to the resulting compositions. T... | 01/25/2000 |
| 5978692 | Apparatus for examining electrochemical effects of in vivo metal implants causing allergic symptoms and/or inflammation in a living organism An apparatus for examining the electrochemical effects of (in vivo) metal implants causing allergic symptoms and/or inflamation in living organism, the apparatus containing two probes and a signal processing circuit connected thereto. One of the probes is... | 11/02/1999 |
| 5944662 | Method and apparatus of determination of chemical species in perspiration A dermal patch to be worn on the skin for increasing the concentration of an analyte expressed through the skin in perspiration to a conveniently measurable level. Included are patches and methods of using such patches to determine the quantity of an anal... | 08/31/1999 |
| 5944671 | Skin test applicator A skin test applicator has a applicator handle (21) and separately storable test elements (13). A complimentary snap-fit attachment structure (33, 43) is provided on the applicator handle and test elements to permit the applicator handle to operatively pi... | 08/31/1999 |
| 5931794 | Allergy testing apparatus An allergen testing pick for receipt in the open top end of a vial of allergen and including a neck for close fit with the top end of such vial. The pick includes a stem depending downwardly from such neck and is formed with a plurality of sharp tines. A ... | 08/03/1999 |
| 5897506 | Pulse rate monitor for allergy detection and control A wrist wearable device for the detection and monitoring of possible allergy symptoms and relation to specific triggering conditions. The device has a visual display and is operatively attached to a human pulse point. It also has a clock/calendar timer, p... | 04/27/1999 |
| 5874226 | In situ immunodetection of antigens An antibody targeted to an antigen is brought into contact with a body component in situ. The resulting antibody/antigen complex is labeled and may be amplified. The label is then detected either in situ or ex situ.... | 02/23/1999 |
| 5871452 | Skin test applicator A skin test applicator has a applicator handle (21) and separately storable test elements (13). A complimentary snap-fit attachment structure (33, 43) is provided on the applicator handle and test elements to permit the applicator handle to operatively pi... | 02/16/1999 |
| 5848976 | Allergic rhinitis relief system and process An allergy treatment that combines graphical indicia and medicinal dosages in at least three logically related physical formats, according to at least three medically related clinical steps. The first physical format, in reference to Step 1, presents a pl... | 12/15/1998 |
| 5820562 | Skin allergy test device having step-shaped punctures A skin allergy test device includes a skin allergy test bar and an antigen container. The skin allergy test bar includes a finger grip, an integral cover having a sealing plug portion, an elongated stem extending therefrom, and a plurality of step-shaped ... | 10/13/1998 |