Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 6934586 | Cardiac resynchronization with adaptive A1-A2 and/or V1-V2 intervals In a system that provides bi-atrial and/or bi-ventricular pacing, the system adjusts an interval between paces delivered to the atria, and/or an interval between paces delivered to the ventricles, as a function of pressure data from the heart. In an exemplary embodi... | 08/23/2005 |
| 6932811 | Transmural ablation device with integral EKG sensor A method and apparatus for transmural ablation using an instrument containing two electrodes or cryogenic probes. A clamping force is exerted on the two electrodes or probes such that the tissue of the hollow organ is clamped therebetween. Bipolar RF energy is then ... | 08/23/2005 |
| 6931271 | System for adaptively deriving ECG chest lead signal data A system provides synthesized chest lead signals of a conventional 12 lead electrocardiogram (ECG) signal set. The system adaptively derives ECG chest lead signals for a plurality of the six ECG chest lead signals of a conventional 12 lead ECG signal set. The system... | 08/16/2005 |
| 6931327 | System and methods for processing analyte sensor data Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the ... | 08/16/2005 |
| 6927721 | Low power A/D converter A comparator is arranged to compare a series of analog voltage signal samples on a first capacitor with a voltage on a second capacitor which is linearly increased or decreased to equal the sample value. The comparator's single output freezes the count of the counte... | 08/09/2005 |
| 6923806 | Transmural ablation device with spring loaded jaws A method and apparatus for transmural ablation using an instrument containing two electrodes or cryogenic probes. A clamping force is exerted on the two electrodes or probes such that the tissue of the hollow organ is clamped therebetween. Bipolar RF energy is then ... | 08/02/2005 |
| 6923772 | Apparatus and method for determining responders to cardiac resynchronization therapy using implantable accelerometers A device for measuring a synchronicity of contraction of a heart to determine if an individual would be a responder to cardiac resynchronization therapy. The device may include a first electrode positioned at a first ventricular wall location to measure movement of ... | 08/02/2005 |
| 6923784 | Therapeutic treatment of disorders based on timing information Disclosed are techniques for operation of neurostimulation or drug delivery devices to stop treatment therapy during times when the patient does not need to be treated. Advantageously, the present invention reduces battery usage and/or drug dosage during periods whe... | 08/02/2005 |
| 6920468 | Event occurrence detection method and apparatus One step of a method of detecting when a certain number of events occur within a time frame causes a database having several event records to include a first event record in response to a first event occurring. Another step of the method updates the first database r... | 07/19/2005 |
| 6918908 | Methods and apparatus for accessing and stabilizing an area of the heart A tubular suction tool for accessing an anatomic surface or anatomic space and particularly the pericardium to access pericardial space and the epicardial surface of the heart to implant cardiac leads in a minimally invasive manner are disclosed. The suction tool in... | 07/19/2005 |
| 6920350 | Method of and apparatus for displaying and analyzing a physiological signal A method of displaying a representation of a physiological signal produced by a patient. The method includes the acts of obtaining a portion of at least one physiological signal acquired from the patient, determining an area to display, and constructing a virtual im... | 07/19/2005 |
| 6917443 | Composite halftone screens with stochastically distributed clusters or lines A method and system of designing a digital halftoning screen for forming images on output sheets according to a set of image signals. The method generates a halftone line screen having multiple levels, each level having multiple line segments, each line segment havi... | 07/12/2005 |
| 6915149 | Method of pacing a heart using implantable device A method of determining an optimal location for implanting a pacemaker electrode includes the steps of pacing a heart from a first location and generating a first map of the heart associated with pacing at the first location. The heart is paced from a second locatio... | 07/05/2005 |
| 6913577 | System and method for diagnosing and monitoring myocardial ischemia for automated remote patient care A system for diagnosing and monitoring myocardial ischemia for automated remote patient care is presented. A database stores monitoring sets containing recorded measures relating to patient information recorded on a substantially continuous basis. A server retrievin... | 07/05/2005 |
| 6912420 | Cardiac rhythm management system for hypotension A cardiac rhythm management system detects hypotension based on a measurement of thoracic impedance. It also provides therapy to treat the hypotension. ... | 06/28/2005 |
| 6908437 | System and method for diagnosing and monitoring congestive heart failure for automated remote patient care A system for diagnosing and monitoring congestive heart failure for automated remote patient care is presented. A database stores a plurality of monitoring sets relating to patient information recorded on a substantially continuous basis. A server retrieving and pro... | 06/21/2005 |
| 6907289 | Triggered storage of diagnostic data associated with compromised resynchronization therapy A method for operating a cardiac rhythm management device used for cardiac resynchronization therapy in which the storage of diagnostic data is triggered by detection of a condition indicating that the effectiveness of the therapy has been compromised. Such diagnost... | 06/14/2005 |
| 6905498 | Transmural ablation device with EKG sensor and pacing electrode An apparatus for transmural ablation using an instrument containing two electrodes. The electrodes extend along the surfaces of mating jaw members which are moveable between open and clamped positions. The electrodes are connected to an RF energy source so that, whe... | 06/14/2005 |
| 6907288 | Cardiac rhythm management system adjusting rate response factor for treating hypotension A cardiac rhythm management system detects hypotension, such as by using thoracic impedance to detect a fluid shift away from the thorax. In response to an episode of detected hypotension, it increases a pacing rate response factor mapping a metabolic need to an ind... | 06/14/2005 |
| 6887207 | Methods and apparatus for estimation of ventricular afterload based on ventricular pressure measurements A method and system incorporated into an IMD that detects changes in ventricular afterload using the morphology of a ventricular blood pressure wave. A peak positive pressure value Pb, peak positive and peak negative derivative pressures dP/dtPP | 05/03/2005 |
| 6875180 | Electromagnetic interference immune tissue invasive system An electromagnetic immune tissue invasive system includes a primary device housing. The primary device housing having a control circuit therein. A shielding is formed around the primary device housing to shield the primary device housing and any circuits therein fro... | 04/05/2005 |
| 6862472 | Medical testing system with an illuminating component A medical testing system includes an instrument for monitoring the electrical activity of a patient's heart. The instrument includes a work surface and an illuminating component for illuminating the work surface. ... | 03/01/2005 |
| 6855112 | Method of and system for health treatment The present invention relates to a method of and a system for treating a health condition of a user. The method includes determining a sensory signal for use to treat the user's health condition, measuring the change to the sensory signal while the user is engaging ... | 02/15/2005 |
| 6839588 | Electrophysiological cardiac mapping system based on a non-contact non-expandable miniature multi-electrode catheter and method therefor A system (10) for determining electrical potentials on an endocardial surface of a heart is provided. The system includes a non-contact, non-expandable, miniature, multi-electrode catheter probe (12), a plurality of electrodes (32) disposed on a... | 01/04/2005 |
| 6837848 | Methods and apparatus for accessing and stabilizing an area of the heart A tubular suction tool for accessing an anatomic surface or anatomic space and particularly the pericardium to access pericardial space and the epicardial surface of the heart to implant cardiac leads in a minimally invasive manner are disclosed. The suction tool in... | 01/04/2005 |
| 6834203 | System and method for prioritizing multiple health disorders for use in automated patient care A system and method for prioritizing multiple health disorders for use in automated patient care is described. A plurality of monitoring sets are retrieved from a database. Each of the monitoring sets include stored measures relating to patient information recorded ... | 12/21/2004 |
| 6827690 | System and method for providing diagnosis and monitoring of myocardial ischemia for use in automated patient care A system and method for providing diagnosis and monitoring of myocardial ischemia for use in automated patient care is described. At least one recorded physiological measure is compared to at least one other recorded physiological measure on a substantially regular ... | 12/07/2004 |
| 6821256 | Non-alternating beat-to-beat fluctuations in T wave morphology The invention features methods to detect T wave lability in an individual, and methods of using T wave lability to detect or monitor abnormal cardiac activities. An individual can be assessed for the risk of sudden death due to cardiovascular pathology using methods... | 11/23/2004 |
| 6821248 | Life supporting apparatus A display 2A, a CCD camera 2C, a speaker/microphone 2D, and service select pads 2Ga through 2Gd which are allotted to the life supporting services to be provided are disposed. As a life supporting service is selected by means of th... | 11/23/2004 |
| 6821254 | Cardiac/respiratory arrest detector The condition of a patient who has signs of cardiopulmonary arrest, is evaluated by applying a pair of electrodes (12, 14) to the chest of the patient and passing a low level of alternating current through the patient to detect changes in transthoracic impeda... | 11/23/2004 |
| 6811537 | System and method for providing diagnosis and monitoring of congestive heart failure for use in automated patient care A system and method for providing diagnosis and monitoring of congestive heart failure for use in automated patient care is described. At least one recorded physiological measure is compared to at least one other recorded physiological measure on a substantially reg... | 11/02/2004 |
| 6795733 | Methods and systems for automatically determining minute ventilation Methods and systems for switching electrode configurations for measuring the transthoracic impedance of patient are described. Various embodiments provide stimulation devices and methods that can automatically adapt to different minute ventilation electrode configur... | 09/21/2004 |
| 6790178 | Physiological monitor and associated computation, display and communication unit Various physiological monitor modules are provided for use with computing devices such as personal digital assistants (PDAs). In some embodiments, the personal digital assistant provides the controls, display, and processing circuitry for the physiological monitor m... | 09/14/2004 |
| 6783498 | Method and system for extracting cardiac parameters from plethysmographic signals A method and system for extracting cardiac parameters from a plethysmographic signal is described wherein the plethysmographic signal is passed through a first filter to remove non-cardiac components of the signal. A second filter averages a plurality of cardiac cyc... | 08/31/2004 |
| 6768919 | Method and system for evaluating cardiac ischemia with heart rate feedback A method of assessing cardiac ischemia in a subject to provide a measure of cardiac or cardiovascular health in that subject is described herein. The method comprises the steps of: (a) collecting a first RR-interval data set from the subject during a stage of gradua... | 07/27/2004 |
| 6749567 | Noninvasive method of measuring physiologic parameters The present invention provides means and methods for noninvasively identifying the blood pressure characteristics in each of the seven types of vessels in the circulatory system, including the central venous pressure (CVP) through a single monitoring system using fl... | 06/15/2004 |
| 6751492 | System for mapping a heart using catheters having ultrasonic position sensors A system for mapping a heart comprises a mapping catheter having an ultrasonic position sensor for insertion into the heart. The system also comprises at least one reference catheter having an ultrasonic position sensor placeable in a fixed position relative to the ... | 06/15/2004 |
| 6748272 | Atrial interval based heart rate variability diagnostic for cardiac rhythm management system A cardiac rhythm management system acquires atrial heart rate variability data. The system provides a graphic or other indication of patient well-being based on the atrial heart rate variability data. Such atrial heart rate variability information provides an indica... | 06/08/2004 |
| 6748258 | Method and devices for heart treatment Various methods and devices for treating a patient who has lost, or is at risk of losing cardiac function by cardiac ischemia are disclosed. Treatment includes first imaging a patient's heart, or a portion thereof, to identify underperfused regions of cardiac muscle... | 06/08/2004 |
| 6746403 | Physiological-signal-analysis device for measuring a blood pressure and method A physiological-signal-analysis device for determining a blood pressure value of a patient and a method of operating the device. The device includes a cuff attachable to an extremity of the patient, a pneumatic system connected to the cuff that supplies a fluid to t... | 06/08/2004 |