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| Number | Title | Issue Date |
| 8190240 | Human cavity gas measurement device and method A device and method for gas measurements in body cavities are provided. These may be any body cavity containing a free gas, where there is an interest in detecting and/or measuring the concentration of said free gas by non-invasive or minimally invasive method. Acco... | 05/29/2012 |
| 8190242 | Portable laser synthesizer for high-speed multi-dimensional spectroscopy Portable, field-deployable laser synthesizer devices designed for multi-dimensional spectrometry and time-resolved and/or hyperspectral imaging include a coherent light source which simultaneously produces a very broad, energetic, discrete spectrum spanning through ... | 05/29/2012 |
| 8190239 | Individual identification device In order to provide an individual identification device for enabling good blood-vessel imaging even in a noncontact way and using an identifying method suitable for noncontact imaging, the device comprises an imaging device for imaging blood vessels of a hand of the... | 05/29/2012 |
| 8190241 | Fluorescence-mediated molecular tomography This invention relates to a fluorescence-mediated molecular tomographic imaging system, designed to detect near-infrared fluorescence activation in deep tissues. The system can use targeted fluorescent molecular probes or highly sensitive activatable fluorescence mo... | 05/29/2012 |
| 8180435 | Method and apparatus for determining target depth, brightness and size within a body region A method of investigating the location and size of a light-emitting source in a subject is disclosed. In practicing the method, one first obtains a light intensity profile by measuring, from a first perspective with a photodetector device, photons which (i) originat... | 05/15/2012 |
| 8175686 | External condition control device based on measurement of brain functions The present invention is helpful in improving stability of repeated measurement and can be applied with high reliability for operations of devices for measurement based on brain functions. A module 801 (a sampler) receives measurement data at each of the meas... | 05/08/2012 |
| 8175687 | Light source for fluorescence diagnosis and photodynamic therapy Disclosed herein is a light source device for fluorescence diagnosis and photodynamic therapy comprising: a plurality of light source means having a wavelength range different from each other and providing selected light; a light path coupling means coupling light e... | 05/08/2012 |
| 8175685 | Process, arrangements and systems for providing frequency domain imaging of a sample Apparatus, arrangement and method are provided for obtaining information associated with an anatomical structure or a sample using optical microscopy. For example, a radiation can be provided which includes at least one first electromagnetic radiation directed to be... | 05/08/2012 |
| 8165661 | Method and apparatus for analyzing amniotic fluid Methods and spectra for monitoring fetal growth and predicting birth weight of an infant prior to birth are provided wherein one or more selected biological markers are measured in a sample of amniotic fluid obtained from a pregnant woman. Levels of the selected bio... | 04/24/2012 |
| 8165662 | Implantable tissue perfusion sensing system and method A medical device for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitt... | 04/24/2012 |
| 8155730 | Composition, method, system, and kit for optical electrophysiology The present invention provides a method of optical electrophysiological probing, including: providing a fluorescing chemical probe; contacting a thick portion of tissue with the fluorescing chemical probe to create a thick portion of treated tissue; applying a first... | 04/10/2012 |
| 8150500 | Micro vein enhancer The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the vein... | 04/03/2012 |
| 8135453 | Method and apparatus for ear canal surface modeling using optical coherence tomography imaging A method and apparatus for generating a three dimensional representation of an ear canal are disclosed whereby an ear canal of a patient is imaged using optical coherence tomography (OCT). In a first embodiment, cross-section images of an ear canal are taken by, for... | 03/13/2012 |
| 8131347 | Optical apparatus for measuring bio-information Disclosed is an apparatus for measuring bio-information of a user. The apparatus includes an input device for receiving basic bio-information of the user, a first light source radiating a first light having a first wavelength on the surface of the skin, a second lig... | 03/06/2012 |
| 8116851 | Living body measurement apparatus with waveguide light source and light extracting pattern Disclosed is a living body measurement apparatus including: a first light source placed on the surface of the skin in a living body and radiating a first light in a visible light wavelength range onto the surface of the skin; a second light source placed on the surf... | 02/14/2012 |
| 8090432 | Implantable tissue perfusion sensing system and method A medical device for sensing cardiac events that includes a plurality of electrodes sensing cardiac signals utilized to identify a cardiac event, a plurality of light sources capable of emitting light at a plurality of wavelengths, and a detector to detect the emitt... | 01/03/2012 |
| 8090431 | Systems and methods for bioluminescent computed tomographic reconstruction An image of an object is synergistically reconstructed using two or multiple imaging modalities. A first reconstructed image, showing structural information of the object is produced using a first imaging modality. The first reconstructed image is segmented, and kno... | 01/03/2012 |
| 8078264 | Intra-operative molecular imaging A system for imaging an abnormal cell and or diseased tissue after topical application of a near infrared protease-specific probe is disclosed. The system includes a protease-specific near infrared (NIRF) imaging probe, means for topically administering the protease... | 12/13/2011 |
| 8078262 | Method for imaging and spectroscopy of tumors and determination of the efficacy of anti-tumor drug therapies The present invention relates to methods of passive infrared imaging and dynamic infrared imaging of a tumor or lesion (“DIR”) where multiple images are taken before, during and after heating or cooling the tumor or lesion. Patterns of intensity of infrared emis... | 12/13/2011 |
| 8078263 | Projection of subsurface structure onto an object's surface An imaging system illuminates an object with infrared light to enhance visibility of buried structure beneath the surface of the object, and projects a visible light image of the buried structure onto the surface of the object. The system may include an infrared lig... | 12/13/2011 |
| 8073531 | Micro vein enhancer The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the vein... | 12/06/2011 |
| 8060188 | Method for imaging variations in tissue viability Prolonged and severe tissue hypoxia results in tissue necrosis in pedicled flaps. We demonstrate the potential of near-infrared spectroscopy for predicting viability of compromised tissue portions. This approach clearly identifies tissue regions with low oxygen supp... | 11/15/2011 |
| 8060187 | Near-infrared spectroscopic analysis of blood vessel walls The invention relates to methods and devices for characterizing tissue in vivo, e.g., in walls of blood vessels, to determine whether the tissue is healthy or diseased, and include methods of displaying results with or without thresholds. ... | 11/15/2011 |
| 8055330 | Sensing gas bubbles in a living body A method of detecting gas bubbles in a living body, comprising: transmitting at least one original electromagnetic signal to a body portion; detecting a signal modulated by a flow of blood in said body portion; and analyzing a perturbation in said signal to determin... | 11/08/2011 |
| 8050745 | Methods and systems for enhanced medical procedure visualization The present invention employs image intensification for medical procedures within the human body. Methods and systems of the invention utilize infrared radiation (e.g. greater than about 750 nm) illumination and visualization of a surgical treatment area. Preferred ... | 11/01/2011 |
| 8050744 | Optical system for measuring metabolism in a body and imaging method In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irrad... | 11/01/2011 |
| 8024027 | Infrared endoscopic balloon probes Balloon probes, adapted for use in endoscopy and other medical procedures, are useful to obtain spectroscopic information reflected or emitted from a tissue of interest in the infrared spectral region. The information collected by the probe is useful in the diagnosi... | 09/20/2011 |
| 8010185 | Method of diagnosing a lower urinary tract disorder A method for sensitively diagnosing lower urinary tract disorders, particularly interstitial cystitis, is provided. The method can visually, simply, and clearly diagnose bladder ulcer without requirement of bladder hydrodistention under anesthesia. In the method, lo... | 08/30/2011 |
| 8000775 | Systems and methods for tomographic image reconstruction Optical tomography systems that provide light of multiple distinct wavelengths from a plurality of sources are described. The systems direct light into mammalian tissue, and light from the mammalian tissue is collected at a plurality of reception points. Collected l... | 08/16/2011 |
| 8000774 | Method and system for intra luminal thrombus detection A method for detecting a complete or partial obstruction in a vessel through an intervening fluid includes receiving spectroscopic responses at different locations of a vessel wall, e.g., a vein or artery, through an intervening fluid, preferably blood. Spectroscopi... | 08/16/2011 |
| 7991455 | Systems and methods for dynamic optical imaging A medical system includes a catheter having an elongated tubular member and an inner core slideably received within the elongated member. The inner core includes an imager on a distal end and is coupled with a control system and an imaging system. The inner core is ... | 08/02/2011 |
| 7983736 | Methods and compositions to reduce scattering of light during therapeutic and diagnostic imaging procedures Disclosed are improved methods and compositions for use in light-based in vivo imaging and treatment. The techniques described involve the use of low-scattering, oxygen-carrying blood substitutes in imaging and treatment methods, including OCT imaging. The invention... | 07/19/2011 |
| 7974683 | Method and system for characterization and mapping of tissue lesions via light and special chemical agents A method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, causing in the biochemical and/or in the functional characteristics of the epithelial tissues during the development of tissue atyp... | 07/05/2011 |
| 7970456 | Method and apparatus for detecting the presence of dermal melanin in epithelial tissue An image of an individual (2) is obtained using a digital camera (1). The image data is then processed by ratio determination module (10) and an image conversion module (12) to analyze the image and determine data representative of the di... | 06/28/2011 |
| 7962199 | Method and apparatus for determination of bone fracture risk using raman spectroscopy A method is disclosed for analyzing keratinized tissue, particularly fingernails, of a subject to diagnose osteoporosis and bone fracture risk. A Raman spectrum of a sample of keratinized tissue is generated. Broad spectral background features of the spectrum are re... | 06/14/2011 |
| 7962198 | System and method for spectral-encoded high-rate hemodynamic tomography An optical tomography system has a group of lasers for generating light of multiple distinct wavelengths within a first wavelength band. Light from these lasers is directed into mammalian tissue at laser-specific locations on the tissue, and light from the mammalian... | 06/14/2011 |
| 7953473 | Method of identifying a lesion inside patient'S tubular organ A lesion identification system for surgical operations has a light marker adapted for placement in the vicinity of a lesion inside an organ of an organism, and a location-identifying device detecting a light emitted from the light marker at an outside of the organ f... | 05/31/2011 |
| 7925331 | Apparatus for displaying a tissue containing a fluorescent dye An apparatus is disclosed for displaying a tissue containing a fluorescent dye at least in sections. It is proposed for the purpose of simplification to record the tissue with a number of cameras from different observation angles while omitting a beam splitter, and ... | 04/12/2011 |
| 7904138 | Micro vein enhancer The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the vein... | 03/08/2011 |
| 7899518 | Non-invasive tissue glucose level monitoring Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels. ... | 03/01/2011 |