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| Number | Title | Issue Date |
| 7941202 | Modular multichannel microelectrode array and methods of making same Some embodiments of the invention comprise a customizable multichannel microelectrode array with a modular planar microfabricated electrode array attached to a carrier and a high density of recording and/or stimulation electrode sites disposed thereon. Novel methods... | 05/10/2011 |
| 7925322 | Shroud-based electrodes having vented gaps Apparatus and method according to the disclosure relate to promoting flow of body fluids in and around and between a substantially planar cardiac-sensing electrode and a shroud member utilizing spacing therebetween and/or one or more apertures, notches, slots and th... | 04/12/2011 |
| 7881765 | Interference-fit shroud-based cardiac electrodes Apparatus and method according to the disclosure relate to minimizing gaps between a substantially planar cardiac-sensing electrode and a shroud member utilizing a so-called interference-fit. For example, a relatively recessed area or aperture formed in an exemplary... | 02/01/2011 |
| 7684844 | System for and method of positioning cells and determining cellular activity thereof A device for positioning at least one cell in at least one addressable position, the device comprising a substrate (12) formed with at least one addressable pore (14) and at least one channel (16) embedded in the substrate and being held in flui... | 03/23/2010 |
| 7643861 | Technique for design, and placement, of a subdermal Ag—Ag/Cl biopotential electrode A chronic subdermal silver-silver/chloride (Ag—Ag/Cl) electrode for the recording of biopotentials is disclosed. The electrode is comprised of an Ag—Ag/Cl distal end that is placed subdermally by various methods. The recording electrode is made of solid, multi-s... | 01/05/2010 |
| 7392093 | Electrical stimulation system including a device for partially shielding electrical energy emitted from one or more electrical stimulation leads implanted in a human's body In one embodiment, a device is provided for partially shielding electrical energy emitted from an electrical stimulation lead implanted in a human's body to enable stimulation of the human's nerve tissue, the lead including one or more electrodes operable to stimula... | 06/24/2008 |
| 7389149 | Connection structures for extra-vascular electrode lead body Connection structures on an extra-vascular electrode lead body improve strain relief and strengthen the transition region where electrical conductors carried by the lead body are joined to individual electrodes at the distal end of the lead. The electrodes include s... | 06/17/2008 |
| 7371215 | Endoscopic instrument for engaging a device A device, system and method for diagnosing and treating a patient is provided where a functional device is attached to a stomach wall. The device in one embodiment provides electrical stimulation of the stomach wall. The device may also have other functional aspects... | 05/13/2008 |
| 7369901 | Myocardial lead and lead system An implantable myocardial stimulation lead comprises a lead body having a distal end and a proximal end, and an electrical connector carried by the proximal end of the lead body. An electrode header carried by the distal end of the lead body has an axis and includes... | 05/06/2008 |
| 7347826 | Packaging sensors for long term implant According to this technique of packaging a sensor device implantable in a living body so as to provide protection of the sensor device and to the living body itself, an electrical conductor of the sensor device is sealed in an insulating substrate extending between ... | 03/25/2008 |
| 7341345 | Ocular wavefront-correction profiling Providing multi-focal visual correction includes determining a plurality of pupil conditions for an eye and determining a target wavefront profile on the basis of the plurality of pupil conditions. ... | 03/11/2008 |
| 7319904 | Percutaneous Surgical lead body There is disclosed a surgical lead comprising two percutaneous lead bodies bonded together. The inventive lead body results in the equivalent of a surgical lead body with columns of electrodes either adjacent to or offset from each other. A bridge of urethane materi... | 01/15/2008 |
| 7310545 | Method and device to form a sensor using isolated cardiomyocytes A method and device are described to form a sensor using a cardiomyocyte by advancing a catheter into the tissue of interest, cardiac in the preferred embodiment, and using the catheter to ablate a cone- or a dome-shaped region to form an electrically isolated secti... | 12/18/2007 |
| 7302296 | Electrical stimulation system and methods for treating phantom limb pain and for providing sensory feedback to an amputee from a prosthetic limb This invention relates to a system and methods for relieving phantomlimb pain in amputees, and for providing an amputee with sensory feedback from a prosthetic limb. The system employs implantable multichannel, multi-chambered interface structures, namely, nerve cuf... | 11/27/2007 |
| 7299092 | Subcutaneous electrode for transthoracic conduction with low profile installation appendage Electrical cardiac therapy devices including electrode lead assemblies having appendages coupled to an electrode. The appendage may take the form of a riser and a head having various characteristics. A further embodiment may include a cover and/or other features cou... | 11/20/2007 |
| 7294108 | Cardiac event microrecorder and method for implanting same A cardiac event microrecorder comprising a hermetically sealed housing is shaped and dimensioned to facilitate the subcutaneous implantation of the microrecorder in a human patient by injection through the lumen of a hypodermic needle. The housing comprises a tubula... | 11/13/2007 |
| 7291161 | Articulated clamping member A grasper is provided having a handle with an elongated shaft secured thereto. First and second jaw members with opposed clamping surfaces are secured to the shaft, with one jaw member being slidably secured with respect to the other jaw member. The jaw members are ... | 11/06/2007 |
| 7288092 | Method and apparatus for ablating cardiac tissue with guide facility A method and apparatus for ablation of cardiac tissue at a selected cardiac location is achieved by providing at least one flexible elongated guide facility having a first end, a second end, and an intermediate portion extending between the first and second ends and... | 10/30/2007 |
| 7283856 | Implantable lead system with seed electrodes A medical electrical lead system for neurological applications has a distal portion having a plurality of independently positionable seed electrodes, each of which may be connected via an interface to an implantable medical device. The interface allows the seed elec... | 10/16/2007 |
| 7283864 | Method and apparatus for identifying patients with wide QRS complexes A medical device programmer or other external system capable of programming an implantable CRM device includes a wide-QRS detection and alerting system. Upon detection of a wide QRS complex, a wide-QRS indicator produces a visual indication of the detection using on... | 10/16/2007 |
| 7274962 | Subcutaneous electrode with improved contact shape for transthoracic conduction Electrical cardiac therapy devices including electrode assemblies having openings for receiving an electrode insertion tool, and methods of inserting such electrode assemblies. The opening(s) are defined on the electrode assemblies to allow an insertion tool to be c... | 09/25/2007 |
| 7274096 | Light transmissive cover, device provided with same and methods for manufacturing them A light transmissive cover for a device comprising: a cover member of light transmissive material; and a junction member joined to the cover member, the junction member being a member used to be joined to the body of the device and having a light interrupting film o... | 09/25/2007 |
| 7257439 | Brain-machine interface systems and methods A system and method for interfacing a brain with a machine. An exemplary embodiment of the present invention employs a vascular approach in which one or more nano-electrodes are deployed in vasculature having a close geometric relationship with proximal innervation.... | 08/14/2007 |
| 7248930 | Medical electrical lead A medical electrical lead for establishing an electrical connection with a tissue of the body, the lead having a lead body and a semi-cylindrical cuff. In the preferred embodiment the semi-cylindrical cuff features one or more electrodes. The semi-cylindrical cuff h... | 07/24/2007 |
| 7241292 | Cardiac ablation device with movable hinge A method and apparatus for transmural ablation using an instrument containing two electrodes or cryogenic probes. A clamping force is exerted on the two electrodes or probes such that the tissue of the hollow organ is clamped therebetween. Bipolar RF energy is then ... | 07/10/2007 |
| 7239925 | Subcutaneous electrode for transthoracic conduction with improved installation characteristics Electrical cardiac therapy devices including lead electrode assemblies for implantation into a patient comprising an electrode having a first face and a second face, and an appendage extending opposite the second face of the electrode, the appendage including an eye... | 07/03/2007 |
| 7236825 | Cardiac activity sensing during pacing in implantable devices A method and device for sensing cardiac activity that includes a first plurality of electrodes forming a first electrode configuration to sense cardiac activity, a second plurality of electrodes forming a second electrode configuration to sense cardiac activity, and... | 06/26/2007 |
| 7235070 | Ablation fluid manifold for ablation catheter An ablation catheter employing one or more manifold arrangements to convey a conductive fluid medium to a target tissue. The manifold includes at least one inlet port in fluid communication with a fluid supply lumen running along at least a portion of the catheter. ... | 06/26/2007 |
| 7232437 | Assessment of lesion transmurality A method and apparatus for treating a body tissue in situ (e.g., an atrial tissue of a heart to treat) atrial fibrillation include a lesion formation tool is positioned against the heart surface. The lesion formation tool includes a guide member having a tissue-oppo... | 06/19/2007 |
| 7225009 | Apparatus for noninvasively measuring hematocrit and associated methods An interface unit for receiving a body part of a subject at which a noninvasive hematocrit measurement is to be obtained includes a narrow monitoring element with a receptacle for receiving at least a portion of the body part and contacts that are configured for est... | 05/29/2007 |
| 7212867 | Directional brain stimulation and recording leads A directional brain stimulation lead assembly provides a lead body and an insulating member defining one or more windows that selectively expose portions of electrodes carried by the lead body to produce a directional stimulation current field. The lead assembly can... | 05/01/2007 |
| 7203548 | Cavernous nerve stimulation via unidirectional propagation of action potentials Methods of using unidirectionally propagating action potentials (UPAPs) for cavernous nerve stimulation and for certain disorders are provided. Stimulators capable of creating such UPAPs include, but are not limited to, miniature implantable stimulators (i.e., micro... | 04/10/2007 |
| 7200446 | Catheter leads for the intrathecal space and method of use Various stimulation catheters are disclosed to lie along and stimulate tissue in the intrathecal space. The electrodes on the leads are various sizes to conserve the battery as well as allowing a more defined area of stimulation. It may also include multiple channel... | 04/03/2007 |
| 7192450 | Porous membranes for use with implantable devices A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity, and interferes with barrier cell layer formation, and a second domain ... | 03/20/2007 |
| 7177701 | System for permanent electrode placement utilizing microelectrode recording methods A lead stimulation/recording system is provided, which is a combination of a permanent DBS stimulating lead and a recording microelectrode. The DBS lead has a lumen extending from the proximal to the distal end of the lead, the lumen having an opening on each end of... | 02/13/2007 |
| 7168165 | Fabrication of electrical medical leads employing multi-filar wire conductors During fabrication of an electrical medical lead, a cut end of a stranded wire conductor is subjected to electrical current sufficient to heat and weld the strands together upon discharge of a high voltage between the cut end and a ground metal plate formed of a mat... | 01/30/2007 |
| 7162289 | Method and apparatus for enhancing the integrity of an implantable sensor device A method and apparatus for enhancing the integrity of an implantable sensor. Voids formed between an outer tubing and a sensor substrate or spacing element may be back-filled with a curable, implantable material, minimizing the extent to which unwanted fluids diffus... | 01/09/2007 |
| 7162310 | Flat wire helix electrode used in screw-in cardiac stimulation leads An implantable endocardial lead for use with a cardiac stimulation device includes an active fixation helix disposed at the distal end of the lead. The helix is constructed of flat wire having a non-circular cross section. The helix may be fixed or movable between a... | 01/09/2007 |
| 7158832 | Electrode designs and methods of use for cardiovascular reflex control devices Devices, systems and methods by which the blood pressure, nervous system activity, and neurohornonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably in t... | 01/02/2007 |
| 7153265 | Anti-inflammatory biosensor for reduced biofouling and enhanced sensor performance A biosensor including an external surface, and an accessory material in close proximity to the external surface. The accessory material includes a coating containing a hydrophilic material and/or a fiber modified to deliver a therapeutic agent. The biosensor modifie... | 12/26/2006 |
