Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 8172746 | Compliant venous graft A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by... | 05/08/2012 |
| 8162815 | Method and device for preserving the vitality and function of a harvested blood vessel A blood vessel preservation device is disclosed comprised of a vessel cannister, cannister cap, vessel alignment insert, pulsatile pump and both inlet and outlet tubing. The vessel canister is advantageously configured as a hollow tube-like structure with a central ... | 04/24/2012 |
| 8123672 | Blood vessel preparation and preservation kit A vessel preparation and preservation kit supports a blood vessel during processing for use in bypass graft surgery. The device comprises a clamshell base having first and second trays latchable in a closed condition and pivotable to an open condition. The first tra... | 02/28/2012 |
| 8088060 | Progenitor endothelial cell capturing with a drug eluting implantable medical device A medical device for implantation into vessels or luminal structures within the body is provided, which stimulates positive blood vessel remodeling. The medical device, such as a stent and a synthetic graft, is provided with a coating with a pharmaceutical compositi... | 01/03/2012 |
| 7959553 | Vein harvesting system and method A tissue illumination system and a method for harvesting a section of a blood vessel from a patient's body for further use. The tissue illumination system includes a light catheter inserted into a lumen of the blood vessel section to illuminate the vessel section an... | 06/14/2011 |
| 7857748 | Photocurable endoprosthesis methods of manufacture Methods of manufacture of endoprostheses comprising one or more photocurable materials are disclosed. The endoprostheses may comprise regions wherein the photocurable materials are selectively disposed about the endoprosthesis and are cured according to desired para... | 12/28/2010 |
| 7833148 | Lumen formation-inducible material and instrument to be inserted into the body The present invention discloses a fistula formation-inducing material having a property of forming a fistula wherein cells are exposed on at least a portion of the fistula luminal surface. This material can be inserted into a living body, using a hollow tubular memb... | 11/16/2010 |
| 7775965 | Decellularized grafts from umbilical cord vessels and process for preparing and using same A tissue graft is disclosed that includes a decellularized umbilical vessel having a luminal surface and an ablumenal surface, wherein the decellularized umbilical vessel is prepared by an automated dissection process. The decellularized umbilical vessel has not bee... | 08/17/2010 |
| 7753840 | Tissue material process for forming bioprosthesis A biomaterial useful for bioprostheses such as bioprosthetic heart valves is provided in which the fixed tissue has improved elastic properties. The high elastin-containing biomaterial is further characterized by having anisotropic properties wherein the biological ... | 07/13/2010 |
| 7744526 | Bioreactor for the manufacture of tissue engineered blood vessels The invention relates to bioreactors having an enclosed chamber, a sheet growth module, a rollable mandrel, and a clamp for holding the sheet to the mandrel for rolling for the manufacture of a tissue engineered blood vessel (TEBV). The TEBV is made from a cultured ... | 06/29/2010 |
| 7736366 | Bone graft forming guide A bone graft forming guide for providing a bone graft and a method of forming a bone graft. The guide includes a main body including a holder for holding a graft material and guide containing a pattern generally corresponding to the desired shaped of the bone graft.... | 06/15/2010 |
| 7682304 | Composite heart valve apparatus manufactured using techniques involving laser machining of tissue Methodology for using laser machining techniques to modify a tissue for use in a medical device. In a representative mode of practice, relatively low energy laser machining is used to thin down at least a portion of a valved jugular vein. The thinned down vein may t... | 03/23/2010 |
| 7666134 | System and method for transplantation of dermal tissue A dermal tissue transplantation system combining a tissue particle harvester, a tissue particle collector, and a chambered dressing. The system provides a harvester capable of harvesting tissue from a donor site on the order of about 100 microns. The integrated tiss... | 02/23/2010 |
| 7658706 | Vascular graft sterilization and decellularization The present technology is related to the field of sterilization and decellularization of allografts or xenografts, specifically to processes that achieve effective removal of the cells contained within a vascular tissue matrix and an effective reduction in potential... | 02/09/2010 |
| 7513866 | Intestine processing device and associated method A device for preparing small intestines of a vertebre is provided. The device includes a body for cooperation with the small intestines. The body defines an external periphery of the body. The device further includes means for longitudinally slitting the small intes... | 04/07/2009 |
| 7438722 | Method for treatment of restenosis A method for inhibiting restenosis is described. The method comprises implanting a stent in a patient's vasculature and simultaneously delivering a restenosis-inhibiting medicine to the treatment site by adjuvant therapy. ... | 10/21/2008 |
| 7429241 | Dural graft and method of preparing the same A dural graft is provided having improved stiffness characteristics relative to conventional dural substitutes. The dural graft can be formed from a collagen material having a stiffness between about 0.1 pounds per inch (lb./in.) and 0.25 lb./in. Relative to the col... | 09/30/2008 |
| 7427261 | System for preparing a craft vessel for anastomosis A system for preparing a graft vessel for anastomosis includes one or more tools held within a functional package. The package includes a tray and tray top, either or both of which may include one or more features configured to hold the contents of the tray securely... | 09/23/2008 |
| 7367983 | Vessel harvesting apparatus A vessel harvesting apparatus including a shaft and a tip formed as a unit with, and positioned at a distal end of, the shaft. A handle is connected to a proximal end of the shaft for allowing an operator to feed and manipulate the tip. The tip defines a vessel rece... | 05/06/2008 |
| 7361368 | Device and method for combining a treatment agent and a gel A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first an... | 04/22/2008 |
| 7358232 | Method for the antibiotic coating of bodies with interconnecting microcavities as well as coated bodies and their usage The invention relates to a method for the antibiotic coating of bodies with interconnecting microcavities as well as bodies coated this way and their usage. The invented method is characterized in that in the microcavities of non-metallic bodies an aqueous solution ... | 04/15/2008 |
| 7354480 | Stent mandrel fixture and system for reducing coating defects A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. ... | 04/08/2008 |
| 7353153 | Method and system for modeling bone structure The present invention discloses a structural and mechanical model and modeling methods for human bone based on bone's hierarchical structure and on its hierarchical mechanical behavior. The model allows for the assessment of bone deformations, computation of strains... | 04/01/2008 |
| 7348175 | Bioreactor with plurality of chambers for conditioning intravascular tissue engineered medical products A microprocessor controlled and instrumented bioreactor for conditioning intravascular tissue engineered medical products. One bioreactor design including an integrated pump to provide a relatively small volume of fluid nutrient. The microprocessor control providing... | 03/25/2008 |
| 7335228 | Stent with ring architecture and axially displaced connector segments An expandable stent is provided. The stent has a ring architecture in which a plurality of connector segments join a plurality of ring structures to form the stent. The ring structures are an endless pattern of unit structures, each of which has two lateral arms and... | 02/26/2008 |
| 7335265 | Apparatus and method for coating stents An apparatus for coating implantable medical devices, such as stents, is disclosed. A method of coating stents using the apparatus is also disclosed. The apparatus includes a barrier or barriers for isolating an area of the stent on which a composition for coating a... | 02/26/2008 |
| 7335391 | Method for coating implantable devices A method of forming a coating for an implantable medical device, such as a stent, is provided which includes applying a composition to the device in an environment having a selected pressure. ... | 02/26/2008 |
| 7331990 | Stents with proximal and distal end elevations A prosthetic stent with a tubular wall having local inwardly or outwardly formed elevations. Stents having such elevations have a higher mechanical stability if bent according to the curvature of the body vessels to be supported or repaired. Also a method for manufa... | 02/19/2008 |
| 7329413 | Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer. ... | 02/12/2008 |
| 7323209 | Apparatus and method for coating stents An apparatus and method is provided for forming coatings on stents. The apparatus includes a temperature adjusting element that can increase or decrease the temperature of the stent. The apparatus can support a stent during the application of a coating composition t... | 01/29/2008 |
| 7322932 | Method for suturelessly attaching a biomaterial to an implantable bioprosthesis frame A bioprosthetic valve graft comprises a valve frame and valve flaps, the latter acting to open or close a valve aperture to directionally control fluid flow through the bioprosthesis. The bioprosthetic valve graft comprises method for suturelessly attaching a biomat... | 01/29/2008 |
| 7323189 | Liquid and low melting coatings for stents A method for forming liquid coatings for medical devices such as stents and angioplasty balloons is provided. The liquid coatings can be made from biodegradable materials in liquid, low melting solid, or wax forms, which preferably degrade in the body without produc... | 01/29/2008 |
| 7318932 | Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same A polymer coating for medical devices based on a derivatized poly(ethylene-co-vinyl alcohol) is disclosed. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include poly(ethylene-co-vinyl a... | 01/15/2008 |
| 7311980 | Polyactive/polylactic acid coatings for an implantable device A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ... | 12/25/2007 |
| 7309352 | Expandable coil stent An implantable coil stent comprises at least a first curved segment and a second curved segment which arc about the longitudinal axis of the stent. An expandable link extends between the second end of the first curved segment and the first end of the second curved s... | 12/18/2007 |
| 7306627 | Acellular matrix grafts of collagen and elastic fiber Acellular matrix grafts are provided with are isolated from natural sources and consist essentially of a collagen and elastin matrix which is devoid of cellular components. The grafts are useful scaffolds which promote the regeneration of muscle tissue and aid in re... | 12/11/2007 |
| 7300662 | Drug/drug delivery systems for the prevention and treatment of vascular disease A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f... | 11/27/2007 |
| 7300444 | Surgical system and method for connecting hollow tissue structures A system for performing anastomosis between a graft vessel and a target vessel includes a tissue effector that may be configured to deploy a user-selectable number of connectors. The system includes an anvil that enters the wall of the target vessel through an entry... | 11/27/2007 |
| 7300673 | Deposition products, composite materials and processes for the production thereof Methods for the production of deposition products including an oxidized metal species under both acidic and alkaline conditions, methods for the production of composite materials including a substrate and the deposition product, and products in the nature of deposit... | 11/27/2007 |
| 7299805 | Scaffold and method for implanting cells An improved method of implanting cells in the body of a patient includes positioning viable cells on a support structure. One or more blood vessels may be connected with the support structure to provide a flow of blood through the support structure. A support struct... | 11/27/2007 |
