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| Number | Title | Issue Date |
| 8095198 | Methods for detecting osteolytic conditions in the body Methods and systems for detecting a biological response indicative of osteolysis or osteolytic pre-conditions in bone. ... | 01/10/2012 |
| 8055322 | Ion sensor for long term use in complex medium Devices and methods for measuring a target ion concentration uses an electrode pair. The pair includes a working electrode and a reference electrode. The working and reference electrodes are ion-selective electrodes (ISEs). The reference ISE can include a sodium ISE... | 11/08/2011 |
| 7389132 | Mold-in method and apparatus The present invention mainly relates to a method and apparatus for measuring the concentration of a solute in a solvent. Disclosed is an apparatus or method for determining the concentration of a solute in a solvent of a solution in a container having a time-varying... | 06/17/2008 |
| 7383071 | Microsensor system and method for measuring data One embodiment is a microprobe. An example of the microprobe comprises a housing having an aperture. This example of the microprobe also comprises an ISFET attached to the housing. The ISFET may have a gate located proximate the aperture. This example of the micropr... | 06/03/2008 |
| 7383072 | Sweat sensor system and method of characterizing the compositional analysis of sweat fluid A method of sensing the concentration level of at least one particular electrolyte in the sweat fluid of a subject, includes providing a sweat sensor system having sweat fluid absorbing material, measuring apparatus for sensing the electrical conductivity of sweat f... | 06/03/2008 |
| 7373195 | Ion sensor for long term use in complex medium Devices and methods for measuring a target ion concentration uses an electrode pair. The pair includes a working electrode and a reference electrode. The working and reference electrodes are ion-selective electrodes (ISEs). The reference ISE can include a sodium ISE... | 05/13/2008 |
| 7371232 | Catheter having circular ablation assembly A catheter particularly useful for ablation lesions within a tubular region of or near the heart is provided. The catheter comprises an elongated flexible tubular catheter body having an axis and proximal and distal ends. An ablation assembly is mounted at the dista... | 05/13/2008 |
| 7367942 | Method and apparatus for testing blood glucose in a reversible infusion line An apparatus for automatically and periodically measuring a patient's blood glucose level wherein the patient has a catheter in a blood vessel and is receiving infusion fluid through the catheter. A testing unit is provided which has a main infusion channel and, in ... | 05/06/2008 |
| 7338778 | Luminescent method for determining cell oxygen consumption The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensit... | 03/04/2008 |
| 7333844 | Uterine tissue monitoring device and method The invention provides a devices, methods and systems to measure and record uterine tissue environment components such as pH during the course of uterine artery occlusion. The uterus becomes ischemic due to the occlusion thereof, and its pH drops sharply within minu... | 02/19/2008 |
| 7239916 | Method and apparatus for automatic implantable medical lead recognition and configuration An automated identification and configuration system for use with an implantable medical device (IMD) is disclosed. The system includes a first communication circuit that is attached to, or otherwise carried by, a detachable component associated with the IMD such as... | 07/03/2007 |
| 7231242 | Method for measuring blood urea level by reverse iontophoresis A method for measuring and determining urea level in human blood by reverse iontophoresis comprising the following steps of: placing an anode electrode on skin, placing a container comprising a solution including u... | 06/12/2007 |
| 7192450 | Porous membranes for use with implantable devices A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity, and interferes with barrier cell layer formation, and a second domain ... | 03/20/2007 |
| 7169289 | Electrochemical detection method and device A device for the electrochemical detection of at least one biochemical molecule contained in a liquid from a group of predetermined biochemical molecules includes a holder (1) for taking up the liquid, with at least one reference electrode (RE) and at least o... | 01/30/2007 |
| 7134999 | Optimized sensor geometry for an implantable glucose sensor An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a c... | 11/14/2006 |
| 7056664 | Method of the electrochemical detection of nucleic acid oligomer hybrids The invention relates to a method for the electrochemical detection of sequence-specific nucleic acid oligomer hybridization events. To this end single DNA/RNA/PNA oligomer strands which at one end are covalently joined to a support surface and at the other, free en... | 06/06/2006 |
| 7018336 | Implantable sensor flush sleeve A apparatus and method for cleaning a sensor tip of an implantable sensor includes a flush sleeve directed towards the sensor tip, a fluid conduit in fluid communication with the flush sleeve, where fluid injected into a first end of a flush sleeve surrounding the s... | 03/28/2006 |
| 7013178 | Implantable medical device communication system An implantable medical device communication system communicates information between an implantable medical device and at least one slave device by way of a two-wire bus. Slave devices may include remote sensors and other implantable medical devices. The implantable ... | 03/14/2006 |
| 6931327 | System and methods for processing analyte sensor data Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the ... | 08/16/2005 |
| 6915147 | Sensing apparatus and process A sensing apparatus with a connector, a sensor lead and a sensor module with a spacer placed over electrodes that have been deposited on a substrate. The spacer may have a space for receiving an enzyme. End portions of the sensor module may be encapsulated, such as ... | 07/05/2005 |
| 6701341 | Scalable real-time ultrasound information processing system An ultrasound information processing system is disclosed in which ultrasound image data is packetized into ultrasound information packets and routed to one or more of a plurality of processors for performing image processing operations on the ultrasound i... | 03/02/2004 |
| 6616614 | Apparatus and method for ascertaining cardiac output and other parameters Apparatus for ascertaining cardiac output of the heart of a patient comprising a control and display module. A venous probe is inserted into a vein in the forearm of the patient and is coupled into the control and display module and provides an electrical... | 09/09/2003 |
| 6411834 | Biological sensor An annul protecting portion 23 having a thickness larger than the thickness of a sensor sensitive portion 1 is provided in such a manner as to surround the sensor sensitive portion 1, the sensor sensitive portion 1 together with the protecting portion 23 ... | 06/25/2002 |
| 6219567 | Monitoring of total ammoniacal concentration in blood Total ammoniacal concentration (TAC) in blood is measured and displayed on a repetitive basis by a controller driven sensor arrangement which may be utilized either with a catheter structure or with a bypass system. The catheter based sensors may be emplo... | 04/17/2001 |
| 6023630 | Probe assembly and apparatus for measuring the PH of a tissue of a human or animal organ A probe assembly includes at least two electrodes for measuring a potential difference between two measurement sites of a tissue of a human or animal organ and at least one sensor for measuring the tissue temperature. The probe assembly further includes a... | 02/08/2000 |
| 5728281 | Implantable medical device including an arrangement for measuring a blood property having a carbon reference electrode An implantable medical device for in vivo electrochemical measurements of blood properties, such as measurements of, inter alia, oxygen pressure, glucose and pH, avoids the problem with the reference electrodes currently in use which cause inflammatory re... | 03/17/1998 |
| 5711861 | Device for monitoring changes in analyte concentration The invention provides an electrochemical sensor system for measuring analyte concentrations in a sample fluid. The invention is particularly useful for measuring analytes such as glucose in a patient. An implantable glucose sensor includes a disc-shaped ... | 01/27/1998 |
| 5698083 | Chemiresistor urea sensor A sensor to detect and quantify urea in fluids resulting from hemodialysis procedures, and in blood and other body fluids. The sensor is based upon a chemiresistor, which consists of an interdigitated array of metal fingers between which a resistance meas... | 12/16/1997 |
| 5680858 | Method and apparatus for in vivo determination of the concentration in a body fluid of metabolically significant substances A method for in vivo determination of the concentration in a body fluid of metabolically significant substance comprises storing of a needle with a sensor in a liquid-filled ampoule, brief insertion of the needle into a patient, recording of the output si... | 10/28/1997 |
| 5617851 | Ultrasonic transdermal system for withdrawing fluid from an organism and determining the concentration of a substance in the fluid A noninvasive method and apparatus for withdrawing fluid from an organism and determining the concentration of a substance in the fluid is disclosed. The noninvasive apparatus comprises a substance concentration sensor (120) that includes an extraction tr... | 04/08/1997 |
| 5513636 | Implantable sensor chip An implantable sensor chip, which is preferably small enough to be injected through a hypodermic needle, includes a base constructed of an electrically insulating material, and at least one sensor for generating an output signal in the presence of a const... | 05/07/1996 |
| 5511547 | Solid state sensors A stabilized bio-inert sensor for the determination of an analyte, especially pO2, pCO2 and pH, in a medium which comprises a chemical indicator sensitive to the analyte in association with a stabilizing substrate formed from a polym... | 04/30/1996 |
| 5507289 | System and method to diagnose bacterial growth A system and a method for monitoring intragastrointestinal concentrations of ammonium, and urease, during short or prolonged periods is presented, as an indicator of the presence and activity of an intragastrointestinal Helicobacter Pylori ("HP") infectio... | 04/16/1996 |
| 5505828 | Calibration solutions useful for analysis of biological fluids and methods employing same Novel calibration solutions are provided which are useful, for example, with sensor assemblies used for analysis of CO2, and optionally, for concurrent analysis of O2, especially in combination infusion fluid delivery/blood chemistry... | 04/09/1996 |
| 5425868 | Sensor for non-invasive, in vivo determination of an analyte and blood flow The sensor (1) comprises a sensor body (3) thermostatable by means of a first thermostating system (14,15) and having an outer surface (3a,40a) for application to the human body (28) in heat conductive relationship therewith, said outer surface (3a,40a) f... | 06/20/1995 |
| 5354448 | Electrochemical sensor An electrochemical sensor for the determination of the partial pressure of oxygen in a bloodstream comprising a cathode and an anode immersed in an electrolyte contained in a chamber defined by an oxygen gas permeable membrane wherein the insulated portio... | 10/11/1994 |
| 5330634 | Calibration solutions useful for analyses of biological fluids and methods employing same Novel calibration solutions are provided which are useful, for example, with sensor assemblies used for analysis of CO2, especially in combination infusion fluid delivery/blood chemistry analysis systems which include a sensor assembly with eac... | 07/19/1994 |
| 5322609 | Device for detecting electrolytes in liquid samples A biosensor device for detecting electrolytes in liquid samples includes a capillary tube having a lumen extending therethrough. This lumen receives and retains liquid to be sampled for electrolytes. A tube holder is engaged at one end of the tube. This t... | 06/21/1994 |
| 5284139 | Hemometrix temperature compensation A method for converting a value for the partial pressure of oxygen (pO2) in blood at a measurement temperature to a corresponding value at a reference temperature (37° C.). A value for pO2 is determined by measurements made in a pat... | 02/08/1994 |
| 5262037 | Electrochemical sensor An electrochemical sensor for the determination of the partial pressure of oxygen in a bloodstream comprising a cathode and an anode immersed in an electrolyte contained in a chamber defined by an oxygen gas permeable membrane wherein the conductor formin... | 11/16/1993 |
