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...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."

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Class 600/345 - Electroanalysis


Subclass of Class 600 - Surgery
Definition: Subject matter wherein detection or measurement of the constituent
No. of patents: 494
Last issue date: 05/22/2012


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NumberTitleIssue Date
8185181Method and apparatus for detecting false hypoglycemic conditions
Embodiments of the present disclosure include detecting a concurrent occurrence of a decrease in monitored analyte level and a corresponding decrease in monitored on-skin temperature, confirming a presence of an impending hypoglycemic condition, and asserting a noti...
05/22/2012
8180423Sensor with increased biocompatibility
Sensors and methods for producing them are disclosed. A cavity is created and filled with a reagent that includes a conductive matrix, enzyme, catalyst, and binding agent, in a preferred embodiment. The cavity is substantially enclosed, leaving enough of an opening ...
05/15/2012
8175673Analyte monitoring device and methods of use
An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor co...
05/08/2012
8155723Device and method for determining analyte levels
Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the ...
04/10/2012
8155722Reference electrodes having an extended lifetime for use in long term amperometric sensors
The present application provides Ag/AgCl based reference electrodes having an extended lifetime that are suitable for use in long term amperometric sensors. Electrochemical sensors equipped with reference electrodes described herein demonstrate considerable stabilit...
04/10/2012
8116840Method of calibrating of an analyte-measurement device, and associated methods, devices and systems
The invention relates to a method for calibrating an analyte-measurement device that is used to evaluate a concentration of analyte in bodily fluid at or from a measurement site in a body. The method involves measuring a concentration, or calibration concentration, ...
02/14/2012
RE43187Methods for analyte sensing and measurement
A method of measuring an analyte concentration in body fluid. The method includes the use of an analyte measuring device that has an analyte sensing element with a sharpened distal end and further has an indicating electrode covered by an absorbent layer. Also, an e...
02/14/2012
8103326Device for monitoring fluid status
A technique for determining a patient's hematocrit by an electrical impedance measurement is described. An implantable device may be configured to utilize the technique in order to assess a cardiac patient's fluid status. In order to determine the hematocrit, the el...
01/24/2012
8060174Analyte sensing biointerface
Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manuf...
11/15/2011
8060173System and methods for processing analyte sensor data
Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the ...
11/15/2011
8032197Method of analyzing for at least one disease or condition marker
A method of using a diffusion-based, continuous-monitoring system to analyze for a disease or condition includes creating a diffusion channel in an area of skin. The diffusion channel is maintained for a desired duration. The level of the disease marker(s) is contin...
10/04/2011
8005524Signal processing for continuous analyte sensor
Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional...
08/23/2011
8000762Body fluid sampling device
Body fluid sampling device comprising a sampling element having a fluid pathway (11) for receiving body fluid, at least a portion of the fluid pathway is open to the environment and further comprising a fluid receiving means (40) being spaced from the ...
08/16/2011
7996054Electrochemical analyte sensor
An electrochemical analyte sensor having conductive traces on a substrate is used to determine a level of analyte in in vitro or in vivo analyte-containing fluids. The electrochemical analyte sensor includes a substrate and conductive material disposed on the substr...
08/09/2011
7979103Catheter-free implantable needle biosensor
Electrochemical biosensors consisting of two or more needle-shaped electrodes for monitoring of molecules such as glucose in the subcutaneous tissue are provided. The two electrodes are parallel to each other, and are fixed perpendicularly to the planar side of a se...
07/12/2011
7974672Device and method for determining analyte levels
Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the...
07/05/2011
7970448Device and method for determining analyte levels
Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the...
06/28/2011
7949381Transcutaneous analyte sensor
The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. ...
05/24/2011
7945301Methods and apparatus for the administration of CO
The present invention relates to a method and apparatus for the administration of carbon monoxide (CO) to a patient. It allows the safe and effective use of carbon monoxide as a medicament. ...
05/17/2011
7933639System and methods for processing analyte sensor data
Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the ...
04/26/2011
7925321System and methods for processing analyte sensor data
Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the ...
04/12/2011
7920906System and methods for processing analyte sensor data for sensor calibration
Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be ...
04/05/2011
7912525Method and apparatus for enhancing the integrity of an implantable sensor device
A method and apparatus for enhancing the integrity of an implantable sensor. Voids formed between an outer tubing and a sensor substrate or spacing element may be back-filled with a curable, implantable material, minimizing the extent to which unwanted fluids diffus...
03/22/2011
7894870Hermetic implantable sensor
At least one conductor is formed at a preselected location on a substrate made of a first insulating material having a high temperature resistance. The conductor is made from a solidified electrically conductive thick film material. A coating made of a second insula...
02/22/2011
7881763Optimized sensor geometry for an implantable glucose sensor
An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a c...
02/01/2011
7869851System and method for determining insulin bolus quantities
A method of computing an insulin bolus quantity when a measured glucose value in a current time interval exceeds a target glucose value for the current time interval and when a time duration of glucose lowering action of the bolus to be administered spans the curren...
01/11/2011
7822454Fluid sampling device with improved analyte detecting member configuration
An assembly is described that combines blood chemical analysis with lancing in a single multiple-test disposable cartridge. The penetrating members can be assembled and sterilized without damaging the analytical chemistry, and the functioning of the present radical ...
10/26/2010
7813780Biosensors and methods for making and using them
Embodiments of the invention provide analyte sensors having optimized permselective membranes and methods for making and using such sensors. Embodiments of the invention also provide analyte sensors such as those having porous matrices coated with an analyte sensing...
10/12/2010
7801582Analyte monitoring and management system and methods therefor
Method and apparatus for providing multiple data receiver units in a data monitoring and management system such as analyte monitoring system where a first data receiver includes all of the functionalities for the data monitoring and management system receiver unit, ...
09/21/2010
7783333Transcutaneous medical device with variable stiffness
The present invention relates generally to variable stiffness transcutaneous medical devices including a distal portion designed to be more flexible than a proximal portion. The variable stiffness can be provided by a variable pitch in one or more wires of the devic...
08/24/2010
7778679Implantable sensor and integrity tests therefor
An implantable sensor includes electronic circuitry for automatically performing on a periodic basis, e.g., every 1 to 24 hours, specified integrity tests which verify proper operation of the sensor. ...
08/17/2010
7774038Real-time self-calibrating sensor system and method
A system and method for calibrating a sensor of a characteristic monitoring system in real time utilizes a self-calibration module for periodic determination of, and compensation for, the IR drop across unwanted resistances in a cell. A current-interrupt switch is u...
08/10/2010
7769420Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction
A sensor is disclosed, for implantation within a blood vessel to monitor a substance in or property of blood. In one embodiment, the sensor detects nitric oxide or a nitric oxide metabolite. In another embodiment, other substances such as glutamate, aspartate, argin...
08/03/2010
7761130Dual electrode system for a continuous analyte sensor
Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interfere...
07/20/2010
7756560Sensor arrangement and method for operating a sensor arrangement
Sensor arrangement having capture molecules immobilized on any of three sensor electrodes, wherein molecules to be detected can hybridize with the capture molecules; a control circuit for applying a first electrical signal to a selected sensor electrode and simultan...
07/13/2010
7751864System and method for operating an electrochemical analyte sensor
A method of operating an electrochemical analyte sensor having one or more electrodes may comprise applying a time-varying input signal to at least one of the one or more electrodes, monitoring a time-varying output signal produced by the sensor in response to appli...
07/06/2010
7725148Sensor with layered electrodes
A thin film sensor, such as a glucose sensor, is provided for transcutaneous placement at a selected site within the body of a patient. The sensor includes several sensor layers that include conductive layers and includes a proximal segment defining conductive conta...
05/25/2010
7697967Method and apparatus for providing analyte sensor insertion
Devices and methods for positioning a portion of a sensor at a first predetermined location, displacing the portion of the sensor from the first predetermined location to a second predetermined location, and detecting one or signals associated with an analyte level ...
04/13/2010
7693560Dual electrode system for a continuous analyte sensor
Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interfere...
04/06/2010
7653425Method and system for providing calibration of an analyte sensor in an analyte monitoring system
Method and apparatus for providing calibration of analyte sensor including applying a control signal, detecting a measured response to the control signal, determining a variance in the detected measured response, and estimating a sensor sensitivity based on the vari...
01/26/2010
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