...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 8095196 | Microsensor needle for pH measurement in tissue A sensor probe for in-situ measurement of pH in a human tissue (e.g., cardiovascular) environment comprises a hollow needle having a tip and a back end. The tip is insertable into the tissue. An optic cable comprises a light conduit surrounded by a cladding. A first... | 01/10/2012 |
| 8060172 | In-vivo information measurement apparatus An in-vivo information measurement apparatus having an insertion part; a light projection unit, provided at a tip of the insertion part, irradiates an examination site with intensity-modulated light which is intensity modulated at a first frequency; a light receivin... | 11/15/2011 |
| 7640046 | Methods and apparatuses for localizing myocardial infarction during catheterization A catheter with a tissue property sensor provides for localization of myocardial infarction (MI) by utilizing one or more differences between properties of infarcted myocardial tissue and properties of normal myocardial tissue. The tissue property sensor is to be pl... | 12/29/2009 |
| 7532920 | Guidewire with optical fiber Apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment of this invention, the apparatus includes a therapeutic guidewire and... | 05/12/2009 |
| 7402426 | Detection of biological molecules by differential partitioning of enzyme substrates and products This invention relates to a method and apparatus for detecting a biological molecule associated with enzyme activity in a sample. The invention is applicable to detecting a microorganism associated with an enzyme in a sample such as water, food, soil, or a biologica... | 07/22/2008 |
| 7385176 | Calibration reflector device, sensor arrangement, and method for sterile packaging of a fiber-optic sensor arrangement A tube-like reflector insert for a sensor is located in a rigid, light-absorbing sleeve that is closed on one side, and forms a two-part reflector body with the sleeve. A nut is glued onto the open side of the sleeve to enclose the reflector insert. The intravasal p... | 06/10/2008 |
| 7373188 | Shunt barrier in pulse oximeter sensor A pulse oximeter sensor comprising a light emitter and a detector disposed on a substrate layer with a plurality of perforations or variations in thickness between the light emitter and the detector. The plurality of perforations or variations in thickness blocks or... | 05/13/2008 |
| 7349618 | Optical feedthrough assembly for use in implantable medical device An optical feedthrough assembly is provided that is configured to be disposed through the canister of an implantable medical device. The optical feedthrough assembly comprises a ferrule having an aperture therethrough and an inner surface therethrough. An optical fi... | 03/25/2008 |
| 7349731 | Reconstructed refractive index spatial maps and method with algorithm The invention provides a means to produce reconstructed refractive index spatial maps that reveal and allow visual separation of normal soft tissue and certain types of tumors. Detector fiber optic bundles positioned on the surface of a soft tissue organ receive and... | 03/25/2008 |
| 7335223 | Apparatus for the treatment of body tissue An apparatus for treating body tissue includes a treatment instrument 1 for treating the body tissue and a measuring unit 3 for measuring the actual value of a parameter of the body tissue at at least one measuring point. An identifier 4 is conn... | 02/26/2008 |
| 7329223 | Catheter with optical fiber sensor An apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment, the apparatus includes an intravascular device to perform a thera... | 02/12/2008 |
| 7322971 | Surgical drain with sensors for monitoring internal tissue condition by transmittance Devices and methods of using a surgical drain, and more particularly a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. Modifications may... | 01/29/2008 |
| 7319896 | Capsule endoscope A capsule endoscope is disclosed that includes a light source, an objective optical system that forms an image of an object that is illuminated by the light source, an image pickup device that receives the image formed by the objective optical system; and a transpar... | 01/15/2008 |
| 7316700 | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties A lancing device, an embodiment of which controls the advancement and retraction of a lancet by monitoring the position of the lancet in conjunction with a lancet controller which incorporates a feedback loop for modulating the lancet driver to follow a predetermine... | 01/08/2008 |
| 7302148 | Test head for optically inspecting workpieces An optical test head comprises a block of material with a plurality of optical paths extending therethrough. At least one of the optical paths is an input optical path for receiving laser light and holding a lens for focusing the laser light on a workpiece that is p... | 11/27/2007 |
| 7300408 | Spectroscopic breath analysis Methods and apparatus for the analysis of exhaled breath by spectroscopy are disclosed. An optical cavity containing the exhaled breath, typically comprising a pair of opposing high reflectivity mirrors, is used to implement a cavity enhanced absorbtion technique. P... | 11/27/2007 |
| 7280858 | Pulse oximetry sensor A pulse oximetry sensor has an emitter adapted to transmit optical radiation of at least two wavelengths into a tissue site and a detector adapted to receive optical radiation from the emitter after tissue site absorption. A tape assembly is adapted to attach the em... | 10/09/2007 |
| 7277740 | Analysis system for reagent-free determination of the concentration of an analyte in living tissue The present invention is generally directed towards a system for reagent-free determination of the concentration of an analyte in vivo. The system comprises a light transmitter for generating monochromatic primary light, a scattered-light percutaneous sensor which i... | 10/02/2007 |
| 7277744 | Early detection of inflammation and infection using infrared thermography The present invention provides a method for the detection of inflammation in animals using infrared thermography. The invention also provides a method for the detection of diseases or disorders that induce inflammation using infrared thermography. The present invent... | 10/02/2007 |
| 7273056 | Optical guidance system for invasive catheter placement Light from a small laser diode is inserted in a distal end of a catheter and passed through an optical fiber that is either included in the lumen or incorporated into the wall of an invasive catheter tube during manufacture. The light is selected to be of a waveleng... | 09/25/2007 |
| 7267671 | Surgical drain with sensors for monitoring fluid lumen Devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. Modifications ... | 09/11/2007 |
| 7246949 | Device for transmitting optical signals The invention relates to a device for transmitting optical signals between at least two components disposed for rotation. The invention excels itself by the provision that at least one micro-optical component is used for beam forming or beam guidance. ... | 07/24/2007 |
| 7244251 | Implanted surgical drain with multiple sensing elements for monitoring internal tissue condition The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the sur... | 07/17/2007 |
| 7242832 | Device for tissue characterization A probe for use in characterizing tissue. The probe includes a plurality of optical fibers and an optical element. Each fiber includes a distal portion and a proximal portion. The fibers transmit light through the fiber to a surrounding area and collect light reflec... | 07/10/2007 |
| 7214190 | Apparatus and method for noninvasive monitoring of analytes in body fluids Noninvasive in vivo real time analyte measurement uses a multitude of sensors binding reversibly to the analyte whereby the response of the sensors to a noninvasive stimulus is altered by their bound versus unbound state. The stimulus and responses are electromagnet... | 05/08/2007 |
| 7192450 | Porous membranes for use with implantable devices A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity, and interferes with barrier cell layer formation, and a second domain ... | 03/20/2007 |
| 7187810 | Methods and systems for correcting image misalignment The invention provides methods of determining a correction for a misalignment between at least two images in a sequence of images due at least in part to sample movement. The methods are applied, for example, in the processing and analysis of a sequence of images of... | 03/06/2007 |
| 7181260 | Apparatus and method for measuring myocardial oxygen consumption Disclosed is a pulmonary artery catheter (“PAC”) that is used in determining myocardial oxygen consumption. Myocardial oxygen consumption is of critical importance because decreased myocardial energy utilization during acute illness may lead to tissue hypoperfus... | 02/20/2007 |
| 7147606 | Urinary diagnostic system having a retrievable sensing device A diagnostic system is disclosed. The diagnostic system comprises a sensing device having a retrieval wire. The sensing device is configured to collect data. The system also includes a deployable housing that has a body defining an interior and an exterior. The hous... | 12/12/2006 |
| 7149562 | Needle with fiberoptic capability A needle with fiber optic capability for spectrophotometric analysis includes a needle assembly including a needle body having an open tip and side radiation ports. A fiber optic element is disposed in the needle assembly for carrying electromagnetic radiation to th... | 12/12/2006 |
| 7144370 | Method and apparatus for imaging of tissue using multi-wavelength ultrasonic tagging of light An imaging apparatus is disclosed. The imaging apparatus includes a source of electromagnetic radiation that is configured to emit electromagnetic radiation at two or more wavelengths through an imaging volume. The imaging apparatus also includes an ultrasound trans... | 12/05/2006 |
| 7134999 | Optimized sensor geometry for an implantable glucose sensor An implantable sensor for use in measuring a concentration of an analyte such as glucose in a bodily fluid, including a body with a sensing region adapted for transport of analytes between the sensor and the bodily fluid, wherein the sensing region is located on a c... | 11/14/2006 |
| 7133071 | Image pickup apparatus An image pickup apparatus using white sheet data for correcting the color of a picked-up image. Each image pickup data is converted into a file by an image filing unit and recorded by a medium-recording unit. Average value data of each color component data for part ... | 11/07/2006 |
| 7132645 | System and method for assessing catheter connection using return loss A system for assessing the quality of the optical connection between a catheter and a console is described that avoids the necessity of a calibration port, although one can still be provided if desired. It operates by monitoring the level of light returning from the... | 11/07/2006 |
| 7125377 | Valve assembly The present invention relates to a valve assembly adapted to be positioned into a urethra in a mammal, including humans, the valve assembly comprising a) a valve holder and b) a valve housing comprising a valve controlling an urine flow from a patient's bladder, the... | 10/24/2006 |
| 7113817 | Optical imaging of blood circulation velocities New devices and methods are provided for noninvasive and noncontact real-time measurements of tissue blood velocity. The invention uses a digital imaging device such as a detector array that allows independent intensity measurements at each pixel to capture images o... | 09/26/2006 |
| 7096053 | Internal biochemical sensing device A biosensing device for detecting biological analytes, and methods of use and manufacture, are disclosed. The device includes a biosensing element that can remain implanted for extended periods of time. The biosensing element is connected to an optical fiber termina... | 08/22/2006 |
| 7068357 | Near infrared chemical imaging microscope A chemical imaging system is provided which uses a near infrared radiation microscope. The system includes an illumination source which illuminates an area of a sample using light in the near infrared radiation wavelength and light in the visible wavelength. A multi... | 06/27/2006 |
| 7062306 | Spectroscopy illuminator with improved delivery efficiency for high optical density and reduced thermal load An improved illuminator for generating broadband light, and for delivering the light to a sample with an improved delivery efficiency, for higher optical density and/or reduced thermal transfer, than achieved with conventional halogen bulb sources. The illuminator e... | 06/13/2006 |
| 7062135 | Method for fabricating curved elements The present invention provides methods for forming convex and concave elements on the ends of supporting members. A convex element may be formed by forming a droplet on the end of the supporting member, then curing the droplet. The size of the droplet may be control... | 06/13/2006 |