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| Number | Title | Issue Date |
| 7341562 | Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion)... | 03/11/2008 |
| 7310552 | Apparatus for indirectly stimulating the vagus nerve with an electrical field An apparatus for indirectly stimulating a vagus nerve of a patient includes electrodes positioned within the esophagus, trachea, or a jugular vein of a patient, on the neck of the patient, or in combinations of these locations. The apparatus further includes a means... | 12/18/2007 |
| 7291502 | Method for performing a non-invasive blood gas test A non-invasive blood gas test is carried out by a method that utilizes a venous blood sample together with a pulse oximeter and a plurality of mathematical equations. The method generates the following data points of the blood: (i) the pH level; (ii) the [H+] concen... | 11/06/2007 |
| 7274955 | Parameter compensated pulse oximeter A monitor has a primary input responsive to a first property of a tissue site. An uncompensated measurement is determinable from the primary input. A parameter input is responsive to a second property associated with the tissue site, where the first property is depe... | 09/25/2007 |
| 7228161 | Temperature indicating oximetry sensor A pulse oximetry sensor having a temperature indicator and a method of operating such a sensor to visually indicate to an operator the temperature of the sensor and hence a measure of the temperature of the tissue location to which the sensor is attached. In one emb... | 06/05/2007 |
| 7147327 | Pupilometer with pupil irregularity detection, pupil tracking, and pupil response detection capability, glaucoma screening capability, intracranial pressure detection capability, and ocular aberration measurement capability A pupilometer having a pupil irregularity or non-uniformity detection capability. The pupilometer may comprise an imaging sensor for generating signals representative of a pupil of an eye, a data processor; and a program executable by the data processor for enabling... | 12/12/2006 |
| 7047054 | Laser diode optical transducer assembly for non-invasive spectrophotometric blood oxygenation monitoring A non-invasive near infrared spectrophotometric monitoring transducer assembly includes a housing member, which is adhered directly on a patient's skin. The housing member contains a prism coupled to a flexible and lightweight single core optical light guide, which ... | 05/16/2006 |
| 7043287 | Method for modulating light penetration depth in tissue and diagnostic applications using same Devices and methods for non-invasively measuring at least one parameter of a sample, such as the presence of a disease condition, progression of a disease state, presence of an analyte, or concentration of an analyte, in a biological sample, such as, for example, a ... | 05/09/2006 |
| 6970729 | Method and device for determining local distribution of a measuring parameter A system and method for determining the local distribution of measurement variables being measured relative to or present in a predefined measurement area of a biological sample wherein in a first optical measuring process the local distribution of a first of the me... | 11/29/2005 |
| 6959211 | Device for capturing thermal spectra from tissue A device and method are provided for use with a noninvasive optical measurement system, such as a thermal gradient spectrometer, for improved determination of analyte concentrations within living tissue. In one embodiment, a wearable window is secured to a patient's... | 10/25/2005 |
| 6931268 | Active pulse blood constituent monitoring A blood glucose monitoring system is disclosed which provides for inducing an active pulse in the blood volume of a patient. The induction of an active pulse results in a cyclic, and periodic change in the flow of blood through a fleshy medium under test. By activel... | 08/16/2005 |
| 6921367 | Device and method for noninvasive continuous determination of physiologic characteristics The invention comprises devices for noninvasively monitoring physiological characteristics of a patient's blood. Generally, probes having radiation emitters and detectors are used to determine absorbance of blood within the patient's tissue to determine various bloo... | 07/26/2005 |
| 6839579 | Temperature indicating oximetry sensor A pulse oximetry sensor having a temperature indicator and a method of operating such a sensor to visually indicate to an operator the temperature of the sensor and hence a measure of the temperature of the tissue location to which the sensor is attached. In one emb... | 01/04/2005 |
| 6718055 | Temporal and spatial correction for perfusion quantification system A medical imaging system includes an imaging device for producing temporally spaced image representations, a memory for storing the image representations, and a processor. The processor aligns the image representations by iteratively deriving a transform between pro... | 04/06/2004 |
| 6714804 | Stereo pulse oximeter An improved pulse oximeter provides for simultaneous, noninvasive oxygen status and photoplethysmograph measurements at both single and multiple sites. In particular, this multiple-site, multiple-parameter pulse oximeter, or “stereo pulse oximeter” simultaneousl... | 03/30/2004 |
| 6640117 | Method and apparatus for minimizing spectral effects attributable to tissue state variations during NIR-based non-invasive blood analyte determination A method and apparatus for minimizing confounding effects in a noninvasive in-vivo spectral measurement caused by fluctuations in tissue state monitors a selected tissue state parameter spectroscopically and maintains the selected parameter within a targe... | 10/28/2003 |
| 6526309 | Transcranial in vivo examination of brain tissue An optical system and method for transcranial in vivo examination of brain tissue includes a spectrophotometer coupled to an array of optical fibers and a processor. The array of optical fibers is constructed to transmit optical radiation of a visible to ... | 02/25/2003 |
| 6480729 | Method for determining blood constituents A method for determining the blood constituents of a patient comprising coupling an oximeter sensor arrangement to a tissue region of the patient; passing first and second lights through the patient's tissue region for a first period of time while the ven... | 11/12/2002 |
| 6466808 | Single device for both heating and temperature measurement in an oximeter sensor A method and apparatus for both heating a patient's skin and for measuring the temperature using the same device, such as a thermistor. Thus, the thermistor generates controlled heat, and is not just used for sensing the temperature. In an oximetry sensor... | 10/15/2002 |
| 6343223 | Oximeter sensor with offset emitters and detector and heating device A method and apparatus for improving blood perfusion by both heating a patient's skin and providing emitters and a detector which are offset from each other. Since the emitters and detector are not directly opposite each other, the light is forced to pass... | 01/29/2002 |
| 5978691 | Device and method for noninvasive continuous determination of blood gases, pH, hemoglobin level, and oxygen content A device and method for noninvasively quantifying important physiological parameters in blood. The device and method utilizes changes in molecular behavior induced by thermal energy of change to facilitate the measurement of the physiological parameters i... | 11/02/1999 |
| 5916154 | Method of enhancing performance in pulse oximetry via electrical stimulation An improved method for optically measuring a characteristic of a patient's blood or tissue is provided which involves first passing an arterialization current (typically from about 1-10 mA AC or DC) through a relatively short tissue segment of a patient (... | 06/29/1999 |
| 5873821 | Lateralization spectrophotometer The present invention utilizes differential measurement of radiation that migrated into two migration paths between two source-detector pairs placed on the head in a manner that each path is localized in a portion of one hemisphere of the brain. The prese... | 02/23/1999 |
| 5743261 | Methods and apparatus for the invasive use of oximeter probes A probe useful for invasively monitoring the oxygen saturation level of blood in the tissue walls of an anatomical canal generally includes a chassis with an electrical connector extending from the proximal end of the chassis and terminating at a plug con... | 04/28/1998 |
| 5590652 | Drive circuit for light-emitting diode in pulse oximeter Disclosed is a drive circuit for driving a light emitting diode in a pulse oximeter comprising at least two light emitting elements different in wavelength for irradiating a living tissue containing an arterial blood; a light receiving element for receivi... | 01/07/1997 |
| 5513642 | Reflectance sensor system A method for determining the content of chemical constituents in a biological tissue medium includes providing a probe comprising a light source and a plurality of photodetector strips circumferentially arranged around the light source. A wavelength for t... | 05/07/1996 |
| 5429129 | Apparatus for determining spectral absorption by a specific substance in a fluid An apparatus for determining spectral absorption by a specific substance in a fluid having an energy source, a sensor an interface device, a support structure and a connector. The energy source directs energy having a predetermined wavelength into the flu... | 07/04/1995 |
| 5408998 | Video based tissue oximetry A video oximetry device and method is provided in which an endoscopic device is used to obtain and determine oxygen saturation levels at a tissue site. A video image illustrating blood oxygen saturation and/or tissue perfusion is derived and displayed.... | 04/25/1995 |
| 5402777 | Methods and devices for facilitated non-invasive oxygen monitoring The present invention is directed to a sensor system for use with a blood characteristic measurement device such as a pulse oximeter, on areas of the body having low normal cutaneous blood flow and for monitoring a blood characteristic such as oxygen satu... | 04/04/1995 |
| 5392777 | Oximeter sensor with perfusion enhancing A method and apparatus for a simple pulse oximeter measurement of an area of the body with a small amount of blood vessels by using a counterirritant to profuse the blood and then apply a modern oximeter probe is disclosed. The counterirritant is either a... | 02/28/1995 |
| 5203329 | Noninvasive reflectance oximeter sensor providing controlled minimum optical detection depth A noninvasive oximeter sensor for controlling and optimizing the minimum detection depth in the tissue of a patient is disclosed. In general, a minimum detection depth of 0.35 mm in the skin is considered optimum. The reflectance oximeter sensor component... | 04/20/1993 |
| 5131391 | Pulse oxymeter having probe with warming means A pulse oxymeter for measuring a blood oxygen saturation of a subject, including a first device for emitting toward a body portion of the subject a first light having a first wavelength and a second light having a second wavelength different from the firs... | 07/21/1992 |
| 5127406 | Apparatus for measuring concentration of substances in blood An apparatus for non-invasively measuring the concentratiuon of a predetermined substance in blood. Light of first and second wavelengths is emitted through a pulsating living tissue, either alternately of simultaneously. The amounts of light of the first... | 07/07/1992 |
| 5125403 | Device and method for engagement of an oximeter probe An electro-optical sensor probe (12) for non-invasive monitoring of blood oxygenation levels is engaged with the blood-perfused tissue (23) of a patient by a device (10) having a woven tube (20) that receives the probe (12) and selectively engages the pro... | 06/30/1992 |
| 5113861 | Method for processing signals, particularly for oximetric measurements on living human tissue A method is used for processing signals, particularly for oximetric measurements on living human tissue. Spurious signals are suppressed with respect to information signals. The spurious signals have a frequency lying in a first frequency range, and the i... | 05/19/1992 |
| 5007423 | Oximeter sensor temperature control A system for measuring blood oxygen saturation uses a noninvasive optical technique. A patient's arterial blood is illuminated with light at two different wavelengths and the intensity of the reflected light is correlated with an oxygen saturation referen... | 04/16/1991 |
| 4926867 | Light-reflecting and heating type oximeter A light-reflecting and heating type oximeter designed to measure non-invasively oxygen saturation in blood contained in a part of a living body by using an optical sensor. The optical sensor has a light-emitting section for emitting measuring light beams ... | 05/22/1990 |
| 4869253 | Method and apparatus for indicating perfusion and oxygen saturation trends in oximetry The present invention discloses a method and apparatus for indicating perfusion and oxygen saturation trends in oximetry. In transmittance and reflectance oximetry, LEDs (40, 42) are typically employed to expose tissue to light at two different wavelength... | 09/26/1989 |
