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| Number | Title | Issue Date |
| 8406837 | Means and methods for cytometric therapies A functionalized tip is incorporated into catheters for the cytometric delivery of cells into the brain and other body parts. For use in the brain, the tip forms part of a neurosurgical probe having a proximal end and a distal end. In addition to the functionalized ... | 03/26/2013 |
| 7653424 | Apparatus for measuring blood glucose concentrations An apparatus for measuring ocular and/or blood glucose levels comprises (a) an irradiating means (10) for irradiating light onto the eye (1) of a user from outside the cornea of the eye to excite an ocular glucose sensor in contact with an... | 01/26/2010 |
| 7406345 | Apparatus for measuring an analyte concentration from an ocular fluid The present invention relates to a hand-held fluorescence photometer and method for measuring an analyte level, preferably a blood glucose level, from an ocular fluid. The photometer is based on a dual beams measuring system and it is capable of defining the correct... | 07/29/2008 |
| 7229175 | Ophthalmic image sensing apparatus An ophthalmic image sensing apparatus includes an examination optical system for examining an eye to be examined, an image sensing optical system for sensing an image of the eye to be examined, an examination image pickup element for picking up the image of the eye ... | 06/12/2007 |
| RE39672 | Method and devices for laser induced fluorescence attenuation spectroscopy The Laser Induced Fluorescence Attenuation Spectroscopy (LIFAS) method and apparatus preferably include a source adapted to emit radiation that is directed at a sample volume in a sample to produce return light from the sample, such return light including modulated ... | 06/05/2007 |
| 7096053 | Internal biochemical sensing device A biosensing device for detecting biological analytes, and methods of use and manufacture, are disclosed. The device includes a biosensing element that can remain implanted for extended periods of time. The biosensing element is connected to an optical fiber termina... | 08/22/2006 |
| 6980842 | Ocular analyte sensor An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled competitor moiety. The amount of detectably labeled competitor moiety... | 12/27/2005 |
| 6922576 | Micro optical sensor device A sensor device for measuring a concentration of a substance within a sample comprises a sensor comprising an optical transmission member having a first end and a second end, the second end having a tip portion attached thereto and an active material incorporated wi... | 07/26/2005 |
| 6850786 | Ocular analyte sensor An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled competitor moiety. The amount of detectably labeled competitor moiety... | 02/01/2005 |
| 6687534 | Fluorescent-light image display apparatus A fluorescent-light image display apparatus for displaying on a monitor a fluorescent-light image emitted from a target area irradiated by a excitation light. A photo-detector inputs the output value of the excitation light into an irregularity controller... | 02/03/2004 |
| 6681127 | Ocular analyte sensor An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled competitor moiety. The amount of detectably labeled compet... | 01/20/2004 |
| 6554775 | Analysis of blood flow Absolute volumetric blood flow of the ocular fundus is quantified using video frames of fluorescent particles circulating in the retina and choroid. An optical apparatus is used to identify movements of particles in a passage of interest, and methods are ... | 04/29/2003 |
| 6438398 | Process and device for measuring tear fluorescein clearance A method of evaluating clearance of fluorescein dye instilled into tear film having a greater sensitivity and specificity for diagnosing a tear film disorder as the cause of a patient's ocular irritation and ocular surface disease than can be achieved usi... | 08/20/2002 |
| 6178340 | Three-dimensional infrared imager for subcutaneous puncture and study of vascular network A novel three-dimensional infrared imager for study of the vascular network so as to cause blood vessels to be visualized for accurate subcutaneous puncture during insertion of a hypodermic needle. The invention uses the properties of near infrared light ... | 01/23/2001 |
| 6124597 | Method and devices for laser induced fluorescence attenuation spectroscopy The Laser Induced Fluorescence Attenuation Spectroscopy (LIFAS) method and apparatus preferably include a source adapted to emit radiation that is directed at a sample volume in a sample to produce return light from the sample, such return light including... | 09/26/2000 |
| 5634458 | Method for determining precorneal retention time of ophthalmic formulations Apparatus and method for measuring ophthalmic formulation retention on the surface of an eye include dissolving a fluorescent macromolecule in an ophthalmic formulation to form a fluorescently labelled formulation; topically administering the fluorescentl... | 06/03/1997 |
| 5553617 | Noninvasive method and apparatus for determining body chemistry The body chemistry of a person is determined by directing a beam of light into the eye of the person, measuring the spectral response of the eye to the beam of light, comparing the measured spectral response to a standard spectral response, and forming a ... | 09/10/1996 |
| 5483958 | Fluorescent-tipped dosimeter probe A solid-state fluorescent dosimeter for monitoring therapy irradiation dosage during a photodynamic therapy procedure. The solid-state fluorescent dosimeter includes an optical fiber -having a distal end and a proximal end, and a solid-state fluorescent t... | 01/16/1996 |
| 5323775 | Diagnostic method for determining precorneal retention time of ophthalmic formulations Apparatus and method for measuring ophthalmic formulation retention on the surface of an eye include dissolving a fluorescent macromolecule in an ophthalmic formulation to form a fluorescently labelled formulation; topically administering the fluorescentl... | 06/28/1994 |
| 5279298 | Method and apparatus to identify and treat neovascular membranes in the eye The method and apparatus of the invention allow a neovascular membrane in the ocular vasculature of the fundus of the eye to be identified and treated while minimizing damage to the sensory retina. First a bolus of fluorescent dye is injected and allowed ... | 01/18/1994 |
| 5203328 | Apparatus and methods for quantitatively measuring molecular changes in the ocular lens Apparatus and methods for noninvasively diagnosing diabetes mellitus, the prediabetic condition, and cataracts in the human (or other) body are disclosed. Diagnoses are made by illuminating ocular lens tissue with a narrow-band light source at a selected ... | 04/20/1993 |
| 4852987 | Device for measuring eye lens opacity The invention is directed to an apparatus for making in vivo measurements of eye lens cloudiness such as caused by cataracta nuclearis. The lens of the human eye has an inherent fluorescence which corresponds to the cloudiness. The apparatus of the invent... | 08/01/1989 |
| 4842401 | Eye diagnosis process An eye examination process includes instilling a neutral pH sulforhodamine B fluorescent dye which is excitable by green light and which fluoresces with orange light in the eye of a patient. The eye is then illuminated with green light and the eye is obse... | 06/27/1989 |
| 4752115 | Optical sensor for monitoring the partial pressure of oxygen A device is described for sensing oxygen, particularly for use in medical applications. The device includes an optical waveguide and an oxygen sensing medium disposed on the waveguide. The sensing medium fluoresces in response to light from a light source... | 06/21/1988 |
| 4597392 | Arrangement for measuring diffusing particles An arrangement for measuring diffusing particles has at least one monochromatic radiation source and a light measuring device, as well as at least one material limited particle-permeable indicator chamber provided with an optical fluorescent indicator whi... | 07/01/1986 |
| 4573778 | Aqueous fluorophotometer Fluorescence of the anterior chamber of an eye is determined by projecting a ribbon of light from the side of the eye through the anterior chamber in a direction generally perpendicular to the optic axis of the eye. The ribbon of light is obtained by imag... | 03/04/1986 |
| 4412543 | Apparatus for determining the concentration of a fluorescent material in an eye A fluorophotometer for determining the concentration of a fluorescent material in an eye, including a light source producing a beam of light traversing a path in the eye to excite the material to emit fluorescence, optics for imaging the path and fluoresc... | 11/01/1983 |
