|7678945||Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same|
A process for preparing derivatized poly(4-hydroxystyrene) having a novolak type structure which comprises the steps of (i) supplying a solution of methanol containing 4-hydroxyphenylmethylcarbinol, (ii) subjecting said solution to an acid catalyzed displacement rea...
|7417172||Perfluoroalkyl vinyl ether compound, process for preparing copolymer by using the compound, and optical plastic materials comprising copolymer prepared by the process|
A novel perfluoroalkyl vinyl ether compound, a process for preparing a copolymer by using the perfluoroalkyl vinyl ether compound, and an optical plastic material comprising a copolymer prepared by the process are provided. More specifically, the perfluoroalkyl viny...
|7411098||Method for the production of tetrahydrogeranylacetone|
The present invention relates to a process for preparing tetrahydrogeranylacetone (tetrahydropseudoionone) by aldol condensation of citral with acetone and subsequent hydrogenation. The invention further relates to the use of thus obtained tetrahydro-geranylacetone ...
An optically active compound having an unsaturated bond at an optically active binding site, wherein the unsaturated bond and a fluorescent substituent or a substituent capable of imparting fluorescence are united in a conjugated manner; and a chiral sensor comprisi...
|7335751||Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same|
The present invention provides a compound having a formula: where R1 is selected from the group consisting of alkyl, —CH2(OC2H4)OCH3, and —(OC2H4)OCH
|7312249||Vitamin D analogues|
Novel biaromatic vitamin D analogues have the general formula (I): and are suited for a wide variety of pharmaceutical applications, whether in human or veterinary medicine, and also for cosmetic applications.
|7282525||Pellicle, producing method thereof and adhesive|
A pellicle comprises a pellicle film and a pellicle frame for supporting the pellicle film, wherein the pellicle film is adhered to the pellicle frame through an adhesive layer comprising a fluorine-containing polymer and a substance resulting from curing of an ultr...
|7208639||Method of producing reduced coenzyme Qas oily product|
The present invention provides a method for obtaining reduced coenzyme Q10 which is useful as an ingredient in foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, drinks, feeds, cosmetics, medicines, remedies, pre...
|6943271||Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same|
A fluorine-containing styrene monomer of the formula (2) is produced by a first, second or third process. The first process includes (a) reacting a compound of the formula (1) with a compound of the formula (3), in the presence of a metal catalyst; (b) reacting the ...
|6756512||Method for producing 2-alkyl-3-chlorophenols|
The invention relates to a novel process for preparing 2-alkyl-3-chlorophenols. ...
|6753444||Method for producing 2,3,5,6-tetrahalogen-xylyidene compounds|
The invention relates to a process for preparing 2,3,5,6-tetrahaloxylylidene compounds of formula (I) where each Hal is independently fluorine or chlorine, and X is fluorine, chlorine, bromine, —O—R, or —O—C(═O...
|6603015||Synthesis of epothilones|
Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment A and C precursors. Segment C precursors are prepared ...
|6570010||Inclusion compounds of vanillyl alcohol derivative in cyclodextrin and compositions containing the same|
An inclusion compound, which comprises a cyclodextrin or a branched cyclodextrin and a vanillyl alcohol derivative represented by the following formula (I) having been included therein: ##STR1## wherein, R represents a C1-6 alkyl group; and a c...
|6437133||Method of catalytically removing a protective group containing an allyl group using a reducing agent|
A method of efficiently removing the protective group from a protected hydroxyl or amino group with an allyl derivative by one step reaction under neutral conditions. A protected hydroxyl or amino group is converted into a free hydroxyl or amino group in ...
|6395910||Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate|
The present invention provides a production method of a 5-phthalancarbonitrile compound, which comprises the use of a novel compound of the formula [I] ##STR1## wherein X is chlorine atom, bromine atom or iodine atom, as a key intermediate. The metho...
|6339176||Method for producing 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol|
It provides a production method of 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol to allow 2,3,5,6-tetrafluoro-1,4-benzenedimethanol to react with an inorganic base in water, and then add dimethyl sulfate and a water-immiscible organic solvent se...
|6326520||Optically active compound and method for producing same|
The invention relates to a method for producing a novel optically active compound represented by the general formula [IV]. This method includes the step of reacting a vinyl ether with a halogenated acetaldehyde in the presence of an optically active binap...
|6326499||Omega chain modified 15-hydroxyeicosatetraenoic acid derivatives and methods of their use for the treatment of dry eye|
Omega chain modified 15-HETE derivatives and methods of their use for treating dry eye are disclosed....
|6320085||Process for the preparation of benzyl-ethers|
##STR1## The subject matter of the invention is the process for the preparation of mixed ethers of formula I, wherein Ar represents an aromatic or one or more heteroatom-containing moiety, optionally substituted by one or more C1-4 alkoxy, meth...
|6307067||Palladium and boron co-catalyzed addition of oxygen nucleophiles to vinyl epoxides|
Nucleophilic oxygen species, such as primary alcohols, carboxylates, and water, are added to vinyl epoxides in a highly regioselective and enantioselective manner, providing a convenient route to enantiomerically enriched 1,2-diols and oxygen-containing h...
|6291721||Processes for the preparation of 2-arylvinyl alkyl ether and 1,4-diaryl-2-fluoro-2-butene compounds|
An improved process for the preparation of 2-arylvinyl alkyl ether compounds of the structural formula I ##STR1## In addition, the present invention provides an improved process for the preparation of 1,4-diaryl-2-fluoro-2-butene compounds of the structur...
|6274635||Alkylated resorcinol derivatives for the treatment of immune diseases|
The present invention provides a method, compounds, and compositions for treating a disease associated with immune dysfunction. In accordance with the method, a pharmacologically-acceptable composition including at least one compound selected from the gro...
|6211387||Diol compounds as intermediates for preparing antimycotic compounds|
A compound of formula (II), wherein R1 is chloro, fluoro or trifluoromethyl; R2 is hydrogen, chloro, fluoro or trifluoromethyl; and R is hydrogen or a protective group for the hydroxy moiety useful as an intermediate for the synthesi...
|6133471||Process for producing chromans|
A process for producing chromans, comprising reacting a phenol, a formaldehyde and an alcohol in the presence of a secondary amine and an acid, to generate an alkoxymethylphenol compound with the ortho position to the phenolic hydroxyl group substituted w...
|6025310||Organic compounds suited to lubricating films on magnetic recording media|
The invention provides novel organic compounds, and more particularly those having excellent lubricity, compatible with lubricating organic compounds having a benzene ring and a phosphazine ring and retaining stability free of hydrolysis for a prolonged p...
|5831102||Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes|
Enzymatically cleavable chemiluminescent 1,2-dioxetane compounds capable of producing light energy when decomposed, substantially stable at room temperature before a bond by which an enzymatically cleavable labile substituent thereof is intentionally clea...
|5780687||Process for preparing 3-oxyalkylpropan-1-ols|
A process for preparing 3-oxyalkylpropan-l-ols by catalytic hydrogenation of 1,3-dioxanes with catalysts comprising a hydrogenation-active component on an acid support....
|5750784||Method for effecting vasodilation with (1,5-inter) aryl prostaglandin derivatives|
The present invention provides a method of effecting vasodilation, comprising: administering to a warm blooded animal in need of such treatment, an effective amount of a (1,5-inter) aryl prostaglandin derivative represented by the Formula I ##STR1## ...
|5728796||Process to react epoxide-containing compounds and aliphatic alcohols|
A process reaction between: (1) a compound that contains one or more epoxide moieties per molecule, and (2) a compound that contains one or more primary aliphatic hydroxyl groups per molecule; is catalyzed by: (3) a catalyst compound containing one or mor...
|5723694||Process for preparing monomethylated or dimethylated phenols|
Phenols monomethylated or dimethylated in the ortho or para position to the OH group and having the formula ##STR1## can be prepared by reaction of tert-alkyl-substituted phenols of the formula ##STR2## in which at least one free ortho or p...
|5698727||1,2-dioxetane derivatives, intermediates for syntheses thereof and methods of producing the intermediates|
A chemiluminescent 1,2-dioxetane derivative having a formula (I): ##STR1## wherein R1 and R4 each represent, individually, hydrogen, an alkyl group, an alkoxyl group, a hydroxyl group, or --OSi(R9 R10 R
|5693251||Optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements|
An optically active phenol useful in the preparation of liquid crystalline compounds which is represented by the formula (V): ##STR1## wherein R2 represents an alkyl or alkoxyalkyl group having 1 to 20 carbon atoms optionally substituted b...
|5600035||Positive photoactive compounds based on 2,6-dinitro benzyl groups and 2,5-dinitro benzyl groups|
Photoreactive compounds are synthesized from 2,5- or 2,6-dintrobenzyl groups. Also disclosed are methods of synthesizing reactive monomers containing 2,5- or 2,6-dintrobenzyl groups....
Novel compounds of Formula 1 ##STR1## or a pharmaceutically acceptable salt or solvate thereof are disclosed. Also disclosed are pharmaceutical compositions containing compounds of Formula 1. Methods of treating allergy, inflammation and hyperpr...
|5500484||2-alkoxy- or acyloxy-2-aryl-1,3-propanediol or dioxane derivative, and process for its production|
A compound that can be converted, at a low cost and in a simple way, into 2-aryl-1,3-propanediols serving as precursors for synthesizing felbamate acting as an antiepileptic has a structure represented by Formula (1): ##STR1## wherein Ar represents a...
|5492917||Endothelin antagonists incorporating a cyclobutane|
Novel compounds of the general structural formula I: ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, pulmonary hypertension, postischemic renal failure, vasospasm, cere...
|5446186||Structure and synthesis of nitrophenyl-EGTA, a caged calcium, intermediates thereof and a method of producing a high photochemical yield of liberated calcium|
The synthesis and compound of a new caged calcium which is an ortho-nitrophenyl derivative of EGTA and various intermediates. It is synthesized in ten steps and 24% overall yield. The photosensitive chelator, nitrophenyl-EGTA, has a Kd for Ca
|5420359||Chlorofluoroether compositions and preparation thereof|
Normally liquid chlorofluoroether compositions consisting or consisting essentially of one or a selected mixture of perhalogenated chlorofluoroether compounds are provided by direct fluorination of the corresponding chloroether or chlorofluoroether precur...
Processes for synthesizing tertiary alkynols by reacting carbonyl-group-containing compounds with alkynes in the presence of a basic catalyst are disclosed. Preferred products are 6,10,14-trimethyl-4-pentadecyn-6-ol compounds having the structure: ##...
|5393776||Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia|
This invention relates to structurally novel acyclic tocotrienol analogs, which are useful for cholesterol/lipid lowering in cases of hypercholesterolemia and hyperlipidemia, and for atherosclerosis. Also provided are pharmaceutical compositions and a met...