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| Number | Title | Issue Date |
| 8008531 | Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis A process for benzylating an alcohol includes mixing 2-benzyloxy-1-methylpyridinium triflate in an aromatic hydrocarbon solvent having a predetermined boiling point; adding an acid scavenger to the mixture; combining the alcohol to be benzylated with the mixture; re... | 08/30/2011 |
| 7897820 | Process for preparing erianin A process for preparing Erianin (Dihydro Combretastation A-4), wherein 3,4,5-trimethoxy benzaldehyde is converted to phosphonium salt or phosphonate ester or the likes thereof, then reacted with isovanillin (3-hydroxyl-4-methoxyl benzaldehyde) including a protected ... | 03/01/2011 |
| 7872160 | Single pot process for the regioselective synthesis of neolignan framework asarones The present invention provides a single pot process for the regioselective synthesis of neolignan framework [3(R)-Ethyl-2(S)-methyl-3-(2″,4″,5″-trimethoxyphenyl)-1-(2′,4′,5′-trimethoxyphenyl)propane from toxic β-isomer rich asarone using montmorillonite... | 01/18/2011 |
| 7312249 | Vitamin D analogues Novel biaromatic vitamin D analogues have the general formula (I): and are suited for a wide variety of pharmaceutical applications, whether in human or veterinary medicine, and also for cosmetic applications. | 12/25/2007 |
| 7285687 | Cannabinoids Compounds of the formula: wherein R, R1 and R4 are defined in the specification, and pharmaceutically acceptable salts, esters and tautomers thereof, having activity at peripheral cannabinoid receptors, commonly designated the CB2 receptor class. The compounds are u... | 10/23/2007 |
| 7220784 | Substituted stilbenes and their reactions The present invention relates to stilbene and quinone compounds related to combretastatin A-4 and their use as anticancer compounds and prodrugs. The compounds include those with an alkyl group on the double bond of cis or trans-stilbenes, compounds with one or more... | 05/22/2007 |
| 7193019 | Process for the production of vinyl compound A process for the production of a vinyl compound of the formula (1), which process comprises reacting a bifunctional phenylene ether oligomer of the formula (2) with a vinylbenzyl halide ... | 03/20/2007 |
| 7179800 | Cannabinoids Compounds of the formula: wherein R, R1 and R4 are defined in the specification, and pharmaceutically acceptable salts, esters and tautomers thereof, having activity at peripheral cannabi... | 02/20/2007 |
| 7122708 | High-functionality polyether polyols and preparation thereof The invention relates to high-functionality polyether polyols of the general formula where each R′1 is an unsubstituted or substituted aliphatic or aromatic radical and each R′2 is an un... | 10/17/2006 |
| 7109245 | Vasoconstrictor cannabinoid analogs Methods and compounds for reversing pathological vasodilation of blood vessels, for example vasodilation caused by activation of CB1-like receptors, by administering to a subject a therapeutically effective amount of a compound sufficient to induce vasoconstriction,... | 09/19/2006 |
| 7049449 | Method for the preparation of lariciresinol cyclolariciresinol and secoisolariciresinol A method for the preparation of lariciresinol, cyclolariciresinol or secoisolariciresinol, which method includes the steps of a) reducing hydroxymatairesinol to give 7-hydroxy-secoisolariciresinol, and b) subjecting the 7-hydroxy-secoisolariciresinol obtained in ste... | 05/23/2006 |
| 6790868 | Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same Antimicrobial compounds, compositions containing the same, and methods of using of the same for reducing the presence of microorganisms on a substrate or in a fluid environment comprising an antimicrobial effective carrier and at least one antimicrobial compounds in... | 09/14/2004 |
| 6746629 | Squarylium compounds, filters for plasma display panels employing them, and plasma display panel devices Coloring matters and filters for plasma display panels, which can effectively screen the neon emission radiated from plasma display panels. Squarylium compounds represented by the following formula (I): [in the formula (... | 06/08/2004 |
| 6689922 | Vitamin D analogues The invention concerns novel bi-aromatic compounds having the formula: ##STR1## which are analogs of vitamin D, the process of preparing them, as well as their use in pharmaceutical compositions in human or veterinary medicine, particularly in dermatology... | 02/10/2004 |
| 6489514 | (-)-Secoisolariciresinol as an antioxidant obtained from a new natural source namely stereospermum personatum This invention relates to a pharmaceutical composition comprising an effective amount of (-)-Secoisolariciresinol together with or associated with an additive useful as an antioxidant; a process for isolating the (-)-Secoisolariciresinol from the plant St... | 12/03/2002 |
| 6472570 | Method for the asymmetric dihydroxylation of olefins, using osmium catalysts This invention relates to process for asymmetric dihydroxylation of olefins using osmium catalysts to obtain monofunctional, bifunctional, and/or polyfunctional chiral 1,2-diols of the formula (I) R1 R2 C(OH)--C(OH)R3 R4 | 10/29/2002 |
| 6362378 | Method for etherifying a benzyl alcohol, resulting products and applications The present invention relates to a process for etherification of a benzyl type alcohol, to the products obtained and to their applications, in particular in the perfumery field. The etherification process of the invention consists of reacting a benzyl typ... | 03/26/2002 |
| 6350777 | Description anti-mitotic agents which inhibit tubulin polymerization Methoxy and ethoxy substituted 3-aroyl-2-arylbenzo[b]thiophenes and benzo[b]thiophene analogues are described for use in inhibiting tubulin polymerization. The compounds' use for treating tumor cells is also described. Additional aspects described here ar... | 02/26/2002 |
| 6133279 | Therapeutic agents for renal diseases and organ preservatives Herein disclosed are therapeutic agents for renal diseases and organ preservatives containing a compound represented by the general formula (1): ##STR1## wherein X represents an oxygen atom or a group represented by the general formula (2): ... | 10/17/2000 |
| 6080790 | Tri-substituted phenyl derivatives and processes for their preparations Compounds of formula (1) ##STR1## are described wherein Y represents a halogen atom or a group --OR1, where R1 is an optionally substituted alkyl group; R2 represents an optionally substituted cycloalkyl or cycloalken... | 06/27/2000 |
| 6040462 | Calix[4 ]arene dibenzo crown ethers, their preparation process and their use for the selective extraction of cesium ion Novel calix[4]arene dibenzo crown ethers useful to selectively extract cesium are represented by the formula: wherein R is a C1 -C10 normal alkyl, a phenyl or a methoxyphenyl, R' is hydrogen, p-tert-butyl or a C1 -C10... | 03/21/2000 |
| 6030746 | Di- and triphenyl monoterpene hydrocarbon derivatives, dissolution inhibitors, and chemically amplified positive resist compositions Di- or triphenyl monoterpene hydrocarbon derivatives of formula (1) are novel. ##STR1## X is a di- or trivalent monoterpene hydrocarbon group, R1 to R3 are hydrogen or an alkyl, alkoxy, alkoxyalkyl, alkenyl or aryl group, R... | 02/29/2000 |
| 5840724 | Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic- o r This invention is directed to the pharmaceutical use of phenyl compounds, which are linked to an aryl moiety by various linkages, for inhibiting tumor necrosis factor. The invention is also directed to the compounds, their preparation and pharmaceutical c... | 11/24/1998 |
| 5780403 | Ash-free detergents their preparation and use in lubricating oil compositions A compound comprised of a moiety derived from an organic nitrogen-containing base and a calixarene moiety in which the hydroxyl substituent (or substituents) is (are) substituted by oligoether chains. Typically, the compounds are complexes of the formula ... | 07/14/1998 |
| 5731463 | Selective alkylation of an alcohol substituted phenol compound The present invention relates to a process for the selective alkylation of intermediates of betaxolol.... | 03/24/1998 |
| 5693807 | Substituted hydroquinone derivatives The invention relates to substituted hydroquinone derivatives of the general formula I ##STR1## wherein R4 is lower alkyl and either R1 is hydroxy, halogen, a group of the formula --P(=O)(R5)R6 (Ia), a grou... | 12/02/1997 |
| 5679696 | Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic-or heteroatom-containing linking group This invention is directed to the pharmaceutical use of phenyl compounds, which are linked to an aryl moiety by various linkages, for inhibiting tumor necrosis factor. The invention is also directed to the compounds, their preparation and pharmaceutical c... | 10/21/1997 |
| 5663207 | Gem-dichlorocyclopropanes as antitumor agents Gem-Dichlorocyclopropanes (Analog II derivatives) which demonstrate antiproliferative activity toward MCF-7 cells, in vitro and are generally not reversed by estradiol or having intrinsic estrogenicity (except the hydroxyphenyl derivative Compound 30). In... | 09/02/1997 |
| 5654331 | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics Diaromatic compounds, characterised in that they correspond to the following general formula: ##STR1## in which: R1 is --CH3, --CH2 OH, --COR8 or --CH2 OCOR9, R8 is H, OH, -... | 08/05/1997 |
| 5621133 | Dopamine agonists Novel compounds having the formula ##STR1## and the pharmaceutically acceptable salts, esters and amides thereof, wherein A is --O--, --S-- or --CR2 R8 --; R1, R2, R3, R4, R5, R | 04/15/1997 |
| 5591884 | Dopamine agonists Novel compounds having the formula ##STR1## and the pharmaceutically acceptable salts, esters and amides thereof, wherein A is --O--, --S-- or --CR2 R8 --; R1, R2, R3, R4, R5, R | 01/07/1997 |
| 5554797 | Tetra (hydroxphenyl) alkanes Positive photoresist compositions comprising, in an organic solvent, at least a) one alkali-soluble resin, b) one photosensitive quinone diazide, c) one aromatic hydroxy compound of formula I ##STR1## wherein each R is --H, C1 -C4 a... | 09/10/1996 |
| 5498803 | Poly(arylene ether)s containing pendent ethynyl groups Poly(arylene ether)s containing pendent ethynyl and substituted ethynyl groups and poly(arylene ether) copolymers containing pendent ethynyl and substituted ethynyl groups are readily prepared from bisphenols containing ethynyl and substituted ethynyl gro... | 03/12/1996 |
| 5412134 | Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol The protected cyclobutanone of the formula ##STR1## is treated with a dialkylaluminum chloride, an alkylaluminum dichloride, a trialkylaluminum compound, diphenylsilane in the presence of tris(triphenylphosphine) rhodium (I) chloride, or iridium tetr... | 05/02/1995 |
| 5395766 | Optically active trans-2-aryl-1-cyclohexanol derivatives and a process for producing the compounds The present invention provides an optically active trans-2-aryl-1-cyclohexanol derivative represented by the following general formula (I). ##STR1## The compounds can be obtained by transesterifiation reaction of the following compound (II) as a... | 03/07/1995 |
| 5366656 | Optically active alcohol and derivatives thereof, liquid crystal composition containing same and liquid crystal device Optically active compounds of general formulae ##STR1## wherein A is O or S, R1 is a hydrogen atom, an alkyl group having 1-22 carbon atoms, a hydroxy containing alkyl group, para-alkyl substituted phenyl, para-alkyl substituted biphenyl, ... | 11/22/1994 |
| 5362822 | Mesogenic adducts An adduct is prepared by reacting (A) a compound containing at least one epoxy group per molecule, with (B) a compound containing at least one epoxide reactive group per molecule selected from the group consisting of phenolic, thiol, secondary amine and c... | 11/08/1994 |
| 5362915 | Phenyl-substituted cycloalkenyl compounds useful as PDE IV inhibitors A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein: R1 is --CH3 or --CH2 CH3 unsubstituted or substituted by 1 to 3 fluorines; X is O or S(O)s where s=0 to 2; R | 11/08/1994 |
| 5288923 | Preparation of ethers of diphenols A process for the preparation of hydroxyalkyl ethers of diphenols is disclosed. Accordingly, aromatic polycarbonate resin is reacted with alkylene diol in the presence of a basic catalyst, at temperatures of 150° to 250° C. at a molar ratio of 514 10 mo... | 02/22/1994 |
| 5274168 | Optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements Disclosed are novel active benzene derivatives represented by the general formula (I): ##STR1## (wherein X represents --COO--, --OCO--, --CH2 O-- or --OCH2 --; A represents a hydrogen atom, a halogen atom or an alkyl or alkoxyl ... | 12/28/1993 |
