...that the x-ray was discovered purely by accident? When German physicist Wilhelm Konrad von Roentgen was experimenting with cathode rays in 1895, he put an activated Crookes tube in a book and went out to lunch. When he returned, he discovered that a key that had also been placed in the book showed up as an image on the developed film!
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| Number | Title | Issue Date |
| 7214831 | Histone deacetylase inhibitors based on alpha-chalcogenmethylcarbonyl compounds Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, for example, an alpha-chalcogenmethylcarbonyl group, such as an alpha-ketothio group, can inhibit histone deacetylase. Histone deacetylase inhibition can re... | 05/08/2007 |
| 7166605 | Probucol nitro-derivatives Probucol derivatives and pharmaceutical compositions containing the same to be employed in treatment or prophylaxis of diseases. ... | 01/23/2007 |
| 7129271 | Compounds for pest control and methods for their use Compounds, compositions, and methods that employ an eremophilane sesguiterpene are presented for controlling an arthropod pest population. The compounds have minimal adverse or toxic effects on humans, non-human animals, and the natural environment. The compounds ma... | 10/31/2006 |
| 6978173 | Device for influencing cell-growth mechanisms in vessels of a human or animal body A device for influencing cell-growth mechanisms in vessels, in particular blood vessels, of a human or animal body, wherein to influence the cell growth mechanisms there is provided an excitation device (5; 5″′) which is adapted to produce stimulation cur... | 12/20/2005 |
| 6930208 | 3-Keto- or 3- oxime-ether-substituted benzoylcyclohexanediones What is described are derivatives of benzoylcyclohexanediones of the formula (I) and their use as herbicides. In this formula (I), R1a, R1b, R1c, R2, R3, R4 | 08/16/2005 |
| 6768025 | Benzoylcyclohexanedione derivatives and their use as herbicides Benzoylcyclohexanedione derivatives of the formula (I) and their use as herbicides are described. In this formula (I), R1, R3, and R4 are various radicals, L—(R2)n | 07/27/2004 |
| 6379590 | Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D ##STR1## wherein A' is se... | 04/30/2002 |
| 6380262 | 5-membered ring compounds ##STR1## 5-Membered ring compounds represented by general formula (I), optically active isomers thereof or salts of the same. These compounds have physiological activities including a carcinostatic effect. In said formula the bond shown by the dotted line... | 04/30/2002 |
| 6218578 | Polymeric film The invention relates to a polymeric film composed of an optically anisotropic material made from a cross-linked synthetic resin composition comprising a polymer network, being obtainable by copolymerization of a mixture comprising (a) at least one monome... | 04/17/2001 |
| 5578470 | Method for preparing thiol compounds with bacterial ଲ-lyase A method for preparing thiol compounds, comprising: (1) reacting cysteine by a non-enzymatical addition reaction with a compound having the formula (R1)(R2)C.dbd.C(R3)--CO--R4 via an --S-- bridge to form a cyste... | 11/26/1996 |
| 5476876 | Di-tert-butylphenol compounds useful as anti-inflammatory agents The subject invention relates to compounds having the structure: ##STR1## wherein (a) X is selected from hydroxy, C1 to about C2 alkanoxy, thiol, C1 to about C2 alkanylthiol, and halo; (b) R and R' are each inde... | 12/19/1995 |
| 5463093 | Palladium complexes and methods for using same in the treatment of tumors or Psoriasis Novel palladium complexes and pharmaceutical compositions comprising the same are provided. Such complexes comprise (palladium)m (lipoic acid)n, wherein m and n are each independently 1 or 2. A process for preparing such complexes is... | 10/31/1995 |
| 5393885 | Carbamic acid derivatives Compounds of the formula ##STR1## in which R1 is halogen, C1 -C3 alkyl, halo-C1 -C3 alkyl, C1 -C3 alkoxy, halo-C1 -C3 alkoxy or cyano and/or two substi... | 02/28/1995 |
| 5182194 | Method for preparing p-mentha-8-thiol-3-one Method for preparing thiol compounds by coupling cysteine having the formula HS--CH2 --CH(NH2)COOH via and --S-- bridge to a hydrocarbon compound and subsequently reacting the cysteine conjugate obtained with ଲ-lyase to form th... | 01/26/1993 |
| 5162353 | Carbacyclins, processes for their preparation, and their use as medicinal agents The invention relates to carbacyclin derivatives with general formula I: ##STR1## in which Y1 stands for the radical --CH2 --X--(CH2)n --R1 or the radical ##STR2## n, 1 or 3, R1, ... | 11/10/1992 |
| 5157156 | Process for preparing an intermediate useful in the syntheis of probucol A process for preparing 2,6-di-t-butyl-4-mercapto-phenol. This is accomplished by sulfonation of the phenol with a silylated sulfonating agent (e.g., trimethylsilyl-chlorosulfonate). The sulfonic acid is then reduced directly or is converted to the sulfon... | 10/20/1992 |
| 5105017 | Leukotriene antagonist intermediates This invention provides novel benzene derivatives which are leukotriene antagonists, formulations of those derivatives, intermediates for preparing the derivatives, and a method of using those derivatives for the treatment of conditions characterized by a... | 04/14/1992 |
| 4894482 | Process for drying hydrogen fluoride-carboxylic acid mixtures A process is provided for removing water from a mixture of hydrogen fluoride (HF), a carboxylic acid, e.g., acetic acid, and water by extractive distillation in the presence of a Lewis base as solvent, which does not azeotrope with water, forms bonds with... | 01/16/1990 |
| 4833164 | 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors 2-Substituted-1-naphthols are 5-lipoxygenase inhibitors which make them useful in the treatment of inflammation, obstructive lung diseases and/or psoriasis. Useful 2-substituent groups are alkyls, alkenyls, alkynyls, cycloalkyls, cycloalkenyls, the groups... | 05/23/1989 |
| 4783213 | Certain 2-(2-substituted benzoyl)-4-(substituted oxy or substituted thio)-1,3-cyclohexanediones Compounds of the formula ##STR1## wherein X is oxy, thio, sulfinyl or sulfonyl; R is halogen; C1 -C2 alkyl; C1 -C2 alkoxy; trifluoromethoxy; difluoromethoxy; nitro; cyano; C1 -C2 haloa... | 11/08/1988 |
| 4672136 | Monoadduct monomers and polyadduct polymers from divinyl ketones Included are monoadduct monomers made from divinyl ketones wherein only one vinyl bond therein has added to it a nucleophilic precursor. Nucleophilic precursors include phenols, thiols, secondary amines, amino acids, hydrocarbyl phosphites and phosphite e... | 06/09/1987 |
| 4621098 | Thioethers and pharmaceutical compositions containing them The present invention provides thioethers of the general formula: ##STR1## wherein Ar is a phenyl radical which is optionally substituted one, two or three times by alkyl, alkenyl, alkoxy, alkylthio, alkanoyl, hydroxyl, hydroxyalkyl, carboxyl, alkoxy... | 11/04/1986 |
| 4367340 | 4-Oxy-cyclopent-2-en-1-one derivative, a prostaglandin intermediate, and the process for its preparation Compounds of the general formula I are disclosed as useful intermediates in the preparation of prostanoids: ##STR1## wherein A represents O or H, ORz ; Rz represents hydrogen or a protecting group; Rx represents hydrogen o... | 01/04/1983 |
| 4343737 | Process for production of thiolcarbamates and the thiolcarbamates obtained by said process A process for producing a thiolcarbamate compound of the following formula ##STR1## wherein R1 represents a hydrogen atom, an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, a halogen atom or a nitro gro... | 08/10/1982 |
| 4206230 | Phenyl cyclopropyl ketone insecticides There are provided insecticidal ketones having the general structure ##STR1## insecticidal compositions containing the ketones and a carrier, and the method of controlling insects with the ketones.... | 06/03/1980 |
| 4171331 | 1 And 2-substituted analogues of certain prostaglandins Disclosed are trans 1 & 2-di(loweralkyl)phosphono; 1 & 2-chloro, bromo and iodo; 1 & 2-thio and 1 & 2-amino analogues of E1, A1, F1, F1ଲ, 11 deoxy E1, 11 deoxy F1ଲ, and 1... | 10/16/1979 |
| 4147643 | Organic compositions useful as additives for fuels and lubricants Compositions useful as additives for fuels and lubricants can be made by reacting (A) an aromatic compound having an OH or SH group attached to an aromatic nucleus and an aromatic hydrogen atom (e.g., a substituted phenol wherein the substituent is an alk... | 04/03/1979 |
| 4088698 | Production of thiophenols A method for preparing thiophenolic compounds is described comprising reacting a phenol and hydrogen sulfide in the presence of a vanadia catalyst. It is preferred to carry out the process of this invention at low pressures, i.e. at pressures lower than 1... | 05/09/1978 |
| 4087445 | N-(5,7-dibromo-1,3-benzoxathiol-2-ylidene)-N-methylmethanaminium bromide, N-(5,7-diiodo-1,3-benzoxathiol-2-ylidene)-N-methylmethanaminium iodide and their preparation N-(5,7-Dibromo-1,3-benzoxathiol-2-ylidene)-N-methylmethanaminium bromide and the analogous diodo iodide, new compounds, are prepared by the thermal rearrangement of O-(2,4,6-tribromophenyl)-N,N-dimethylthiocarbamate and O-(2,4,6-triiodophenyl)-N,N-dimethy... | 05/02/1978 |
| 4086265 | Preparation of catechol derivatives A method of preparing derivatives of aromatic compounds including the catechol function ##STR1## by replacement of one of the hydroxyls by mercaptan ##STR2## Cathechol or a multi-ring compound (naphthyl-, anthryl-, phenanthryl-, etc.) conta... | 04/25/1978 |
| 4056568 | 2,6-Dialkyl-4-hydroxysulfenyl chlorides 2,6-dialkyl-4-hydroxysulfenyl chlorides are prepared by reacting sulfur chloride with an equimolar amount of a 3,5-dialkyl phenol. The sulfenyl chlorides are novel compounds useful as intermediates in the preparation of other compounds. For example, they ... | 11/01/1977 |
| 4006186 | Process for the preparation of thiophenols Process for the production of thiophenols of the formula ##STR1## in which N IS AN INTEGER FROM 0 TO 5, INCLUSIVE, AND R is hydroxy, nitro, halogen, alkyl of from 1 to 6 carbon atoms, alkoxy of from 1 to 6 carbon atoms, amino, monoalkylamino or dialkylami... | 02/01/1977 |
| 4005071 | P-Chlorobenzyl N,N-hexamethylenethiolcarbamate Certain novel thiolcarbamate compounds of the general formula ##STR1## wherein X is alkyl, e.g., lower alkyl, e.g., of from 1 to 4 carbon atoms, lower alkoxy of from, e.g., 1 to 3 carbon atoms, or halogen, e.g., chlorine or bromine, preferably chlori... | 01/25/1977 |
| 3968264 | Flavoring agent Enhancement of the flavor of foodstuffs is achieved by the addition of an effective flavor-modifying amount of an aromatic sulfur compound of the formula: ##SPC1## Wherein R1 is hydrogen, hydroxy, alkoxy or alkyl and R2 is hydro... | 07/06/1976 |
| 3952064 | Process for producing mercaptophenols A selective process for producing mercaptophenols is achieved by reducing the polysulfides which result from contacting phenols with sulfur chloride in a polar solvent reaction medium including a hydrogen chloride promoter, wherein the concentration of ph... | 04/20/1976 |