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| Number | Title | Issue Date |
| 8093434 | Crystal polymorph of fluorene derivative and production method thereof A method of producing a crystal polymorph of 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene, comprising the steps of reacting fluorenone and 2-phenoxyethanol in the presence of a heteropolyacid, initiating deposition o... | 01/10/2012 |
| 7732645 | Aromatic vinyl ether compounds Aromatic vinyl ether compounds represented by Formula (1) or by Formula (2) wherein each R and R′ is a hydrogen atom or a group represented by Formula (3) and wherein the remain... | 06/08/2010 |
| 7671241 | Host material for blue OLED and white light emitting device utilizing the same The invention provides a host material for organic light emitting diodes, having the general formula: wherein R1 is selected from a C1-8 alkyl group, each R2 is independently selected from a... | 03/02/2010 |
| 7439537 | Divinylfluorenes New divinylfluorene compounds according to one of formulae (II) or (III): a new synthetic route to divinylfluorene compounds; and the use of the new compounds as sensitizers, optical brighteners and electroluminescent mater... | 10/21/2008 |
| 7335659 | Substituted 10-aryl-11-benzo[]fluorenes and 7-aryl-5, 6-dihydro-benzo[]anthracenes for selective effects on estrogen receptors This invention provides a compound, or its possible salt, having the formula, wherein: Re and ′Re are OH, optionally independently etherified or esterified; Z is —CH2CH2— or... | 02/26/2008 |
| 7321044 | Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate products for the production of tissue-selective estrogens The invention relates to intermediate products and a new process for the production of benzocycloheptene C. The process for the production of its new intermediate products according to the invention starts from eco... | 01/22/2008 |
| 7279607 | Process for producing anthracene diether An industrially advantageous process is presented whereby a high purity anthracene diether can be produced in good yield. An aqueous medium containing an alkali salt of 9,10-anthracenediol is added to an organic solvent containing an etherifying agent in the ... | 10/09/2007 |
| 7235699 | Alkoxy-substituted indanes and the production thereof The present invention relates to alkoxy-substituted indanes, their preparation and use and to the preparation and use of the corresponding alkoxy-substituted indanones. ... | 06/26/2007 |
| 7166747 | Synthesis of soluble functionalized lithium initiators This invention discloses a process for making dilithium initiators in high purity. This process can be conducted in the absence of amines which is desirable since amines can act as modifiers for anionic polymerizations. The dilithium compounds made are highly desira... | 01/23/2007 |
| 7122708 | High-functionality polyether polyols and preparation thereof The invention relates to high-functionality polyether polyols of the general formula where each R′1 is an unsubstituted or substituted aliphatic or aromatic radical and each R′2 is an un... | 10/17/2006 |
| 7115279 | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer. ... | 10/03/2006 |
| 7115784 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or a... | 10/03/2006 |
| 7074829 | Antiestrogens, process for their production and their pharmaceutical use This invention relates to new antiestrogens of the general formula in which the substituents have the meanings that are explained in more detail in the description. The new compounds are a) pure antiestrogens o... | 07/11/2006 |
| 7049449 | Method for the preparation of lariciresinol cyclolariciresinol and secoisolariciresinol A method for the preparation of lariciresinol, cyclolariciresinol or secoisolariciresinol, which method includes the steps of a) reducing hydroxymatairesinol to give 7-hydroxy-secoisolariciresinol, and b) subjecting the 7-hydroxy-secoisolariciresinol obtained in ste... | 05/23/2006 |
| 7001926 | Tubulin binding agents and corresponding prodrug constructs A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin... | 02/21/2006 |
| 6974877 | Process for preparing pentacene derivatives A process for preparing substituted pentacene compounds comprises the step of cyclizing substituted bis(benzyl)phthalic acids using an acid composition comprising trifluoromethanesulfonic acid, the substituted bis(benzyl)phthalic acids being represented by the follo... | 12/13/2005 |
| 6949557 | Hydroanthracene based compounds as anticancer agents The invention relates to the use of novel anthracene based compounds for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds. The invention relates more specifically to the use of hy... | 09/27/2005 |
| 6903114 | Derivatives of naphthalene with COMT inhibiting activity Compounds of formula (I′), wherein A, R1 to R3 and t are as defined in the disclosure, exhibit COMT enzyme inhibiting activity so that they are useful as COMT inhibitors. ... | 06/07/2005 |
| 6875895 | Bis (diphenylvinyl) arene compound Provided is a bis(diphenylvinyl)arene compound having a reactive functional group on phenyl group, represented by below formula (1), wherein, Ar is an arylene group and has one or more substituents; R1-R | 04/05/2005 |
| 6864291 | Agonists specific for the peripheral cannabinoid receptor The invention provides novel pharmaceutical compositions comprising as the active ingredient 4-phenyl pinene derivatives which are specific for the peripheral cannabinoid receptors. In particular, the compounds of the invention binds efficiently to CB2 but do not bi... | 03/08/2005 |
| 6864396 | Substituted pentacene semiconductors Substituted pentacene compounds comprise at least one substituent selected from the group consisting of electron-donating substituents, halogen substituents, and combinations thereof; the substituent(s) each being bonded to a carbon atom of a terminal ring of pentac... | 03/08/2005 |
| 6768025 | Benzoylcyclohexanedione derivatives and their use as herbicides Benzoylcyclohexanedione derivatives of the formula (I) and their use as herbicides are described. In this formula (I), R1, R3, and R4 are various radicals, L—(R2)n | 07/27/2004 |
| 6756375 | 10-Aryl-11h-benzo[b]fluorene derivatives and analogs for medicinal use The invention provides for a non-steroidal compound having the formula wherein Re and ′Re are OH, optionally independently etherified or esterified; Z is —CH2— or —CH2C... | 06/29/2004 |
| 6727277 | Compounds affecting cholesterol absorption A class of novel compounds is described for use in affecting lymphatic absorption of cholesterol. Compounds of particular interest are defined by Formula I: or a pharmaceutically acceptable salt thereof. ... | 04/27/2004 |
| 6723870 | Method for producing anthracenes Disclosed is a method for producing anthracene of formula (II) below by mixing a reaction mixture with a primary alcohol, wherein the reaction mixture is a reaction mixture obtained by reacting a metal hydride with an anthraquinone of formula (I): ... | 04/20/2004 |
| 6703504 | Conformationally constrained compounds as dendrimer cores There are provided novel chemical compounds and their uses in the preparation of polymers and oligomers, and the preparation of such compounds. In certain embodiments there are provided dendritic polymers and oligomers, of a type having at least four poly... | 03/09/2004 |
| 6686371 | Non-steroidal, tetracylic compounds for estrogen-related treatments The invention provides non-steroidal estrogenic compounds with estrogenic and anti-estrogenic compounds effects for treatment of estrogen-deficiency related disorders, which compounds are having formula (I) wherein, one of Ra or Rb i... | 02/03/2004 |
| 6646168 | Supported osmates, process for preparation thereof, and a process for the preparation of chiral vicinal diols using supported osmate catalyst The present invention provides a supported osmate useful as a reusable catalyst in the preparation of vicinal diols. The present invention also relates to a process for the preparation of supported osmates of the formula (S--NR3)2 Os... | 11/11/2003 |
| 6639114 | Hydroformylation catalyst comprising a complex with ligands having a structure derived from bisphenol A Ethylenically unsaturated compounds are hydroformylated in the presence of a hydroformylation catalyst comprising at least one complex of a metal of transition group VIII with at least one phosphorus-containing compound as ligand, where this compound cont... | 10/28/2003 |
| 6630607 | Aromatic methylidene compounds, aromatic aldehyde compounds and methylstyryl compounds used to prepare the methylidene compounds, and methods for preparing these compounds Aromatic methylidene compounds of the following general formula ##STR1## wherein R11 and R21 independently in each occurrence represent an unsubstituted or substituted alkyl or alkoxy group, a halogen, a cyano group or a nitro gr... | 10/07/2003 |
| 6608212 | Process for preparing vinylaromatic compounds The present invention provides a process for preparing a vinylaromatic compound comprising reacting an arylmetal reagent selected from arylmagnesium reagents and aryllithium reagents with a vinylphosphate in the presence of a palladium catalyst. The prese... | 08/19/2003 |
| 6608232 | Method for preparing a benzylic-type ether The invention concerns a method for preparing a benzylic-type ether from an aromatic compound. The inventive method for preparing a benzylic-type ether from an aromatic compound is characterised in that it consists in: in a first step, acylating an aromat... | 08/19/2003 |
| 6593374 | Tubulin binding ligands and corresponding prodrug constructs A diverse set of tubulin binding ligands have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl--aryl, pseudo pi stacking distances appropriate for molecular recogniti... | 07/15/2003 |
| 6573278 | Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases The present invention relates to new aryl ether sulphonamides and analogues, processes for their preparation and their use for the treatment of neurodegenerative disorders, in particular for the prophylaxis and treatment of neurodegenerative disorders, in... | 06/03/2003 |
| 6541673 | Process for oxyalkylating phenolic compounds Phenolic polyether polyols are prepared by a two stage oxyalkylation process, a first stage performed at a high oxyalkylation temperature and a second stage at a lower oxyalkylation temperature. Despite the use of high temperature during oxyalkylation, po... | 04/01/2003 |
| 6528676 | Estrogenic compounds as anti-mitotic agents The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found belo... | 03/04/2003 |
| 6379590 | Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D ##STR1## wherein A' is se... | 04/30/2002 |
| 6344153 | Helical discotic switch The present invention provides liquid crystal having a spiral coil structure and a dipole moment along its axis and a helical discotic switch using the same, wherein the helicene compound has the structure: ##STR1## wherein X is O, or S and Y is --O--C(.d... | 02/05/2002 |
| 6342642 | 1,4-diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds The present invention provides novel 1,4-diaryl-2-fluoro-1-buten-3-ol compounds of the structural formula I ##STR1## a method for the preparation of those formula I compounds, and the use of those formula I compounds in the preparation of 1,4-diaryl-... | 01/29/2002 |
| 6333437 | Method for purifying a bromine compound A method for purifying a bromine compound by depositing the bromine compound represented by the following general formula (1) as solid particles from a crude solution containing the bromine compound: ##STR1## wherein (i) the crude solution is supplied int... | 12/25/2001 |
