Class 568/585 - Plural rings containing

Subclass of Class 568 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which contain at least two rings.
No. of patents: 112
Last issue date: 11/23/2010

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Number	Title	Issue Date
7838706	Preparation and the use of ethoxy combretastatins and their prodrugs The invention disclosed a total synthesis process of novel ethoxy combretastatins and their prodrugs. Combretastatins are chemically modified by ethoxy substituted on the 4′-position of their B aryl ring and are converted to be their soluble prodrugs of phosphate ...	11/23/2010
7674938	Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen or lower alkyl; R3, R4...	03/09/2010
7579507	Polymorphic crystal of 4′-{2-[ (1S, 2R)—2- hydroxy-2- (4-hydroxyphenyl)-1-methylethylamino]ethoxy} - 3 - isopropyl-3′, 5′ -dimethylbiphenyl- 4 - carboxylic acid hydrochloride Crystals of a salt of 4′-{2-[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethylamino]ethoxy}-3-isopropyl-3′,5′-dimethylbiphenyl-4-carboxylic acid. The α type, β type and γ type crystals produced by treating hydrochloride of 4′-{2-[(1S,2R)-2-hydroxy-2-(4-...	08/25/2009
7423185	Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen or lower alkyl; R3, R4...	09/09/2008
7183445	Cyclohexyl derivatives as selective estrogen receptor modulators The present invention is directed to novel cyclohexyl derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and diseases mediated by an estrogen receptor. ...	02/27/2007
7157419	Growth factor binding molecules Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid sidechains. The growth factor binding molecules specifically bind various growt...	01/02/2007
7109164	Aniline-derived ligands for the thyroid receptor New thyroid receptor ligands are provided which have the general formula in which: X is —O—, —S—, —CH2—, —CO—, or —NH—; Y is —(...	09/19/2006
7091292	Bridged bi-aromatic catalysts, complexes, and methods of using the same Ligands, compositions, metal-ligand complexes and arrays with substituted bridged bis-biaromatic ligands, and methods of making and using the same, are disclosed that are useful in the catalysis of transformations such as the polymerization of monomers into polymers...	08/15/2006
6933322	Substituted naphthylenes for the treatment of non-insulin dependent diabetes mellitus This invention provides compounds of formula I, having the structure wherein R1, R4, A, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof, that are useful in...	08/23/2005
6800605	Aniline-derived ligands for the thyroid receptor New thyroid receptor ligands are provided which have the general formula in which: X is —O—, —S—, —CH2—, —CO—, or —NH—; Y is —(CH2)n— where n is an i...	10/05/2004
6794544	Method for the preparation of tetrahydrobenzothiepines Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds...	09/21/2004
6762329	Diaryl ether condensation reactions One aspect of the present invention relates to novel reaction conditions that allow the efficient synthesis of diaryl ethers from arenes bearing a leaving group and arenols under relatively mild conditions. Another aspect of the present invention relates to the dram...	07/13/2004
6703504	Conformationally constrained compounds as dendrimer cores There are provided novel chemical compounds and their uses in the preparation of polymers and oligomers, and the preparation of such compounds. In certain embodiments there are provided dendritic polymers and oligomers, of a type having at least four poly...	03/09/2004
6420130	Optical molecular sensors for cytochrome P450 activity The invention provides a compound, useful as an optical probe or sensor of the activity of at least one cytochrome P450 enzyme, and methods of using the compound to screen candidate drugs, and candidate drugs identified by these methods. The optical probe...	07/16/2002
6395939	Diaryl ether condensation reactions One aspect of the present invention relates to novel reaction conditions that allow the efficient synthesis of diaryl ethers from arenes bearing a leaving group and arenols under relatively mild conditions. Another aspect of the present invention relates ...	05/28/2002
6362380	Preparation of nitrobiphenyls A process for preparing nitrobiphenyls of the formula I ##STR1## where m is 1 or 2, R is halogen R' or OR', where R' is a C-organic radical which may carry groups inert under the reaction conditions, n is 0, 1, 2 or 3, and, in the case of n being 2 or 3, ...	03/26/2002
6333080	Liquid-crystal alkenyltolan derivative, liquid-crystal composition, and liquid-crystal display element A liquid crystalline alkenyltolan derivative expressed by the general formula Ct H2t-1 --G--(CH2)m --A1 --B1 --(A2 --B2)n --(A3 --B3)p...	12/25/2001
6198007	Process for the preparation of 1-substituted 2,4-dinitrobenzenes Provided is a process for the preparation of specific 1-substituted 2,4-dinitrobenzenes by reaction of 1-halogeno-2,4-dinitrobenzenes with mono-alkali metal salts of specific diols, in which the 1-halogeno-2,4-dinitrobenzene and the mono-alkali metal salt...	03/06/2001
6087542	Process for preparing nitrobiphenylene A process for preparing nitrobiphenyls of the formula I ##STR1## where m is 1 or 2, H is halogen R' or OR', where R' is a C-organic radical which may carry groups inert under the reaction conditions, n is 0, 1, 2 or 3, and, in the case of n being 2 or 3, ...	07/11/2000
6084132	Fluorescent dyes Fluorescent dyes which fluoresce in a variety of colors are produced from substituted and un-substituted 6-ring and 8-ring aromatic diketones by reductive alkylation with alkyl halides in the presence of zinc....	07/04/2000
6080790	Tri-substituted phenyl derivatives and processes for their preparations Compounds of formula (1) ##STR1## are described wherein Y represents a halogen atom or a group --OR1, where R1 is an optionally substituted alkyl group; R2 represents an optionally substituted cycloalkyl or cycloalken...	06/27/2000
6028219	Process for the nitration of diphenylethers A process for the preparation of a compound of general formula I: ##STR1## wherein: R1 is hydrogen or C1 -C6 alkyl, C2 -C6 alkenyl or C2 -C6 alkynyl, any of which may optionally ...	02/22/2000
5952531	Nitration process A process for the nitration of an aromatic or heteroaromatic compound with a nitrating agent comprising nitric acid or a mixture of nitric and sulphuric acids, characterised in that nitration is performed in a solvent comprising at least 50% v/v of a C	09/14/1999
5874611	Butenyl hydroquinone derivatives A hydroquinone derivative (I) represented by the following formula: ##STR1## wherein R1 is a hydrogen atom, acetyl group or benzoyl group, such hydroquinone derivative being useful as an intermediate for chroman derivatives useful as a blo...	02/23/1999
5827333	Substituted biphenyl ethers and fuel compositions containing the same Substituted biphenyl polyalkyl ethers having the formula: ##STR1## wherein R1 is hydrogen or hydroxyl; R2 is hydroxyl, cyano, nitro, amino, aminomethyl, N-alkylamino or N-alkylaminomethyl wherein the alkyl group contains 1 to ab...	10/27/1998
5675039	Bis-m-benzotrifluoride compounds Disclosed are bis-meta-benzotrifluoride compounds having the general formula ##STR1## where each A is independently selected from the group consisting of NO2, NH2, and NH3+ Z-, Z- is ...	10/07/1997
5492917	Endothelin antagonists incorporating a cyclobutane Novel compounds of the general structural formula I: ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, pulmonary hypertension, postischemic renal failure, vasospasm, cere...	02/20/1996
5475149	Method for ether formation A process for the preparation of 4,4'-dinitro-2,2'-di(trifluoromethyl)diphenyl ether according to the equation ##STR1## where X is F, Cl, Br or I, where the inorganic base is selected from the group consisting of alkali metal hydroxides, alkali ...	12/12/1995
5447656	Meta-substituted aromatic compounds having six-membered rings, for use in liquid-crystal mixtures Meta-substituted aromatic compounds having six-membered rings, for use in liquid-crystal mixtures Compounds of the formula I ##STR1## in which X is CH, CF or N, R2 is, for example, an alkyl, ether or ester group, which may also contain a c...	09/05/1995
5434304	Process for preparing formoterol and related compounds The present invention is directed to a process for preparing formoterol and related compounds and derivatives thereof and their pharmacologically and pharmaceutically acceptable fumarate salts and/or solvates. The present invention is also directed to cer...	07/18/1995
5401436	Optically active compound An optically active compound of the formula (I): ##STR1## R is a halogen atom, a cyano group, an alkyl group having 1 to 18 carbon atoms, an alkoxy group having 1 to 18 carbon atoms, --R' or --O--R' group; R' is a ##STR2## group, wherein Y ...	03/28/1995
5393885	Carbamic acid derivatives Compounds of the formula ##STR1## in which R1 is halogen, C1 -C3 alkyl, halo-C1 -C3 alkyl, C1 -C3 alkoxy, halo-C1 -C3 alkoxy or cyano and/or two substi...	02/28/1995
5312999	Propoxybenzene derivatives and process for preparing the same Propoxybenzene derivatives represented by the following formula ##STR1## wherein Ra represents a nitro group, an amino group which may have a protecting group or an --NHCH.dbd.C(COO--C1-6 -Alkyl)2 group, Rb represents a hydrogen...	05/17/1994
5288742	଱,଱ dialkylbenzyl derivatives The invention concerns ଱,଱-dialkylbenzyl derivatives of the formula I ##STR1## wherein Ar1 is phenyl or naphthyl, or a 10-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally cont...	02/22/1994
5264511	Polymers of bis (ethynylstyryl) benzene and related monomers Monomers, B-stage polymers, C-stage polymers, cured polymers and electricy conducting polymers of acetylene-terminated aromatic monomers containing three benzene rings separated by ethylene groups are disclosed. These new polymers can withstand aggressiv...	11/23/1993
5260428	Agent for the detection of substances with hydrolase activity A process for the detection of substances with hydrolase activity in a sample by mixing the sample with a hydrolase substrate and an oxidising agent, and the evaluating the resultant colour intensity, wherein, as hydrolase substrate, there is used at leas...	11/09/1993
5200111	Optically active compound An optically active compound of the formula (I): ##STR1## R is a halogen atom, a cyano group, an alkyl group having 1 to 18 carbon atoms, an alkoxy group having 1 to 18 carbon atoms --R' or --O--R' group; R' is a ##STR2## group, wherein Y i...	04/06/1993
5183587	Liquid crystalline compound A liquid crystal compound having a relatively low viscosity, a superior compatibility with other liquid crystalline compounds and suitable for preparing a liquid crystal device having a high response rate, and a superior liquid crystal composition contain...	02/02/1993
5132423	Method for conducting organic reactions using guanidinium salt as phase transfer catalyst Reactions between a solid polar and a non-polar compound, especially nucleophilic aromatic substitution reactions between an alkali metal salt of a hydroxyaromatic compound or thio analog thereof and an activated halo- or nitro-substituted aromatic compou...	07/21/1992
5110983	Hexafluoroisopropyl-containing monomers, process for their preparation and their use Compounds of the formula I ##STR1## can be prepared by various process steps from 2-(4-methylphenyl)-2-hexafluoroisopropanol. Hexafluoroisopropyl-containing monomers are important starting compounds in the preparation of linear polycarboxamides and p...	05/05/1992

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Class 568/585 - Plural rings containing