Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 7387865 | Composition containing a photoacid generator monomer, substrate coated with the composition, method for synthesizing a compound on a substrate using the composition, and microarray produced according to the method A composition containing a photoacid generator monomer and surfactant, and a method for synthesizing a compound on a substrate using the composition are provided. The method includes bonding a layer of first molecules having an acid labile protecting group to a soli... | 06/17/2008 |
| 7217841 | Stabilizers and antiozonants for elastomers Elastomers which have excellent stability to prevent oxidative, thermal, dynamic, light-induced and/or ozone-induced degradation comprise, as stabilizers, at least one compound of the formula I [R—S(═O)m—CH2—CH(OH)—CH2 | 05/15/2007 |
| 7119123 | Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use Antimicrobially active 4-methyl-4-aryl-2-pentanols of the Formula 1 below, methods for the preparation of these compounds and their use as antimicrobial active compounds are described. Surprisingly, compounds of th... | 10/10/2006 |
| 7025904 | Method for improving adhesion of water-based inks to halogen-containing resin articles Flexible and semi-rigid vinyl chloride resin compositions comprising a combination of a latent mercaptan and a zinc salt of oxidized polyethylene (a zinc ionomer) as a heat stabilizer are substantially free from the offensive odor typically associated with mercaptan... | 04/11/2006 |
| 6982353 | C2-disubstituted indan-1-ol compounds, their derivatives, processes for their preparation, and their use as pharmaceuticals The present invention is directed to C2-disubstituted indan-1-ol systems of the Formula I, physiologically acceptable salts and physiologically functional derivatives thereof, and pharmaceutical compositions comprising... | 01/03/2006 |
| 6943272 | Norbornane and norbornene derivatives, use thereof and perfumed products containing same The invention concerns a novel compounds of formula (I), wherein the dotted line bond is present or not, and wherein R1 represents: when the dotted line bond is present —CHCH3OH or —CHCH3OCOR or —CHCH3XCH2... | 09/13/2005 |
| 6765116 | Process of preparing a fluid rare earth alkoxylation catalyst A process to prepare an improved fluid rare earth phosphate catalyst composition useful in preparing alkylene oxide adducts of organic compounds having active hydrogen atoms is provided. The catalyst is prepared by dissolving a rare earth salt in a C9-C | 07/20/2004 |
| 6610218 | Latent mercaptans as multi-functional additives for halogen-containing polymer compositions Halogen-containing polymer compositions comprising a latent mercaptan-containing heat stabilizer composition substantially free from the offensive odor typically associated with mercaptans are protected during processing by the degradation products of the... | 08/26/2003 |
| 6479519 | Substituted anilides The invention is directed to physiologically active compounds of formula (I): ##STR1## wherein: R1 is hydrogen, halogen, hydroxy, lower alkyl or lower alkoxy; X1, X2 and X6 independently represent N or CR10 | 11/12/2002 |
| 6379590 | Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D ##STR1## wherein A' is se... | 04/30/2002 |
| 6326519 | Diallylic sulfides and processes for preparing the same Diallylic sulfides represented by Formula I ##STR1## wherein: R1 and R2 are independently chosen from the group consisting of --CHO, --CH2 Cl, --CH2 Br, --CH2 I, --CH2 OH, CH2 OS... | 12/04/2001 |
| 6204297 | Nonionic gemini surfactants Novel nonionic gemini surfactants are extremely effective emulsifiers for oil-in-water emulsions that provide improved detergency at even low concentration levels. The surfactants are characterized by the formula: ##STR1## wherein R1 is indepen... | 03/20/2001 |
| 6175042 | Process for preparing perfluoroalkyl aryl sulfides and novel perfluoroalkyl aryl sulfides This invention relates to a process for preparing perfluoroalkyl aryl sulfides by reaction of disulfides with alkali metal salts of aliphatic perfluorocarboxylic acids in the presence of a high-boiling aprotic solvent at elevated temperature and reduced p... | 01/16/2001 |
| 6130346 | Process for preparing an organic compound from an oxirane-containing compound in the presence of a tris(triaminophosphoranylideneamino)phosphine oxide A process for preparing an organic compound, comprising conducting an organic reaction in the presence of a phosphine oxide represented by formula (1); ##STR1## where R1 is the same or different and each represents a hydrogen or hydro... | 10/10/2000 |
| 6049009 | Production method of optically active trans-vinylsulfide alcohol A method for producing an optically active trans-vinylsulfide alcohol having the formula: ##STR1## wherein R1 represents an alkyl group or an aryl group, comprising the step of reducing a trans-vinylsulfide ketone with a borane reducing ag... | 04/11/2000 |
| 5998674 | Bromine compound production method Method of producing a bromine compound having an aliphatic unsaturated bond which includes reacting a compound having an aliphatic unsaturated bond represented by the following general formula (1) with bromine: R1 --O--Ar1 --Y--Ar2 | 12/07/1999 |
| 5866596 | 3,4-diaryloxazolone derivatives, their methods of preparation and their uses in therapeutics The present invention relates to the derivatives of formula: ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.... | 02/02/1999 |
| 5798396 | Sulfonium salt-containing compounds and initiators of polymerization The present invention is directed to sulfonium salt-containing compounds represented by a following general formula; ##STR1## wherein R1 is alkyl containing from 1 to 18 carbon atoms, hydroxy, alkoxy containing from 1 to 18 carbon atoms, a... | 08/25/1998 |
| 5777176 | 4,4-(disubstituted)cyclohexan-1-ol dimers and related compounds The present invention relates to novel dimers of 4.4-(disubstituted)cyclohexan-1-ol dimers and delated compounds, pharmaceutical compositions containing these compounds, and their use in treating allergic and inflammatory diseases and for inhibiting the ... | 07/07/1998 |
| 5770729 | Ozonide reducing agent The present invention provides an ozonide reducing agent for use in the ozonolysis reaction of an organic compound, the ozonide reducing agent finding wide applications, and being safe and inexpensive from a commercial viewpoint and easy to treat for disp... | 06/23/1998 |
| 5679871 | Hydroxyalklylation of phenols A process for the production of hydroxyalkylated phenolic or hydroxyalkylated thiophenolic compounds is disclosed. The process comprises providing a phenolic or thiophenolic compound, a cyclic organic carbonate compound, and a catalyst selected from the g... | 10/21/1997 |
| 5670690 | Compositions and methods for removal of detergents Compounds having detergent properties are disclosed. When a modifying reagent is brought into contact with these compounds, the detergent properties are decreased. These compounds are useful, for example, as solubilizing agents for microbial antigens and/... | 09/23/1997 |
| 5639903 | Sulfonium salt compounds and initiators of polymerization The present invention is related to sulfonium salt compounds useful as an initiator of cationic polymerization and represented by a following general formula (I): ##STR1## wherein R1 is benzyl, phenyl, etc., R2, R3 an... | 06/17/1997 |
| 5563161 | Alcohols and ethers with aromatic substituents as tachykinin-antagonists Compounds of formula (I), and salt and prodrugs thereof, wherein Q is optionally substituted phenyl or benzhydryl; R1 is H; optionally substituted C1-6 alkyl; optionally substituted phenyl(C1-4 alkyl); C2-6 alke... | 10/08/1996 |
| 5446186 | Structure and synthesis of nitrophenyl-EGTA, a caged calcium, intermediates thereof and a method of producing a high photochemical yield of liberated calcium The synthesis and compound of a new caged calcium which is an ortho-nitrophenyl derivative of EGTA and various intermediates. It is synthesized in ten steps and 24% overall yield. The photosensitive chelator, nitrophenyl-EGTA, has a Kd for Ca | 08/29/1995 |
| 5393885 | Carbamic acid derivatives Compounds of the formula ##STR1## in which R1 is halogen, C1 -C3 alkyl, halo-C1 -C3 alkyl, C1 -C3 alkoxy, halo-C1 -C3 alkoxy or cyano and/or two substi... | 02/28/1995 |
| 5393776 | Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia This invention relates to structurally novel acyclic tocotrienol analogs, which are useful for cholesterol/lipid lowering in cases of hypercholesterolemia and hyperlipidemia, and for atherosclerosis. Also provided are pharmaceutical compositions and a met... | 02/28/1995 |
| 5380900 | -methylenecyclopentanone derivative and process for producing the same Disclosed herein is an -methylene-cyclopentanone derivative represented by the formula [I] below which is useful as an intermediate for pharmaceuticals and insecticides, especially prostaglandins. Also disclosed herein is a process for producing th... | 01/10/1995 |
| 5288742 | , dialkylbenzyl derivatives The invention concerns ,-dialkylbenzyl derivatives of the formula I ##STR1## wherein Ar1 is phenyl or naphthyl, or a 10-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally cont... | 02/22/1994 |
| 5283368 | Process for producing alkoxylated thio-compounds A composition comprising a base and an alkoxylated compound selected from the group consisting of an alkoxylated alcohol, alkoxylated mercaptan, and mixtures thereof can be used to catalyze the reaction of a sulfur-containing compound such as, for example... | 02/01/1994 |
| 5254708 | Substituted cyclic ketones, substituted cyclic enones, and process for producing the same The present invention relates to substituted cyclopentanone and cyclohexanone derivatives and substituted cyclopentenone and cyclohexenone derivatives, which are useful as intermediates for pharmaceutical products and agricultural chemicals and especially... | 10/19/1993 |
| 5231208 | Substituted cyclic ketones, substituted cyclic enones, and process for producing the same The present invention relates to substituted cyclopentanone and cyclohexanone derivatives and substituted cyclopentenone and cyclohexenone derivatives, which are useful as intermediates for pharmaceutical products and agricultural chemicals and especially... | 07/27/1993 |
| 5227505 | Substituted cyclic ketones, substituted cyclic enones, and process for producing the same The present invention relates to substituted cyclopentanone and cyclohexanone derivatives and substituted cyclopentenone and cyclohexenone derivatives, which are useful as intermediates for pharmaceutical products and agricultural chemicals and especially... | 07/13/1993 |
| 5219562 | Hair treating composition A hair treating composition comprising one or more thioglyceryl ethers provides effective wave formation, with a minimized mercapto smell and minimized irritation to the skin.... | 06/15/1993 |
| 5214070 | Diaryl ether cycloalkanes The invention concerns a diaryl ether cycloalkane of the formula I, or a pharmaceutically-acceptable salt thereof, ##STR1## wherein Ar1 is optionally substituted phenyl or naphthyl; X1 is oxy, thio, sulphinyl or sulphonyl; Ar | 05/25/1993 |
| 5210325 | Alkoxylation process catalyzed by supported rare earth elements Alkylene oxide adducts of organic compounds having active hydrogen atoms are prepared by a process which comprises contacting and reacting an alkylene oxide reactant comprising one or more vicinal alkylene oxides with an active hydrogen containing reactan... | 05/11/1993 |
| 5208388 | 2,2-difluorocyclopropyl derivatives 2,2-Difluorocyclopropyl derivatives of the formula ##STR1## in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl and X represents hydroxymethyl, 2-hydroxyethyl, isocyanato, amino, amino hydrohalide or a radical o... | 05/04/1993 |
| 5189164 | Processes for the synthesis of syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof A process for synthesizing syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof from the corresponding keto-hydroxy compounds, which process comprises: providing a reaction medium comprising sodium... | 02/23/1993 |
| 5162589 | Alkoxylation process catalyzed by sodium- or potassium barium phosphate Alkylene oxide adducts of organic compounds having active hydrogen atoms are prepared by a process which comprises contacting and reacting an alkylene oxide reactant comprising one or more vicinal alkylene oxides with an active hydrogen containing reactan... | 11/10/1992 |
| 5145996 | Heteroatom containing perfluoroalkyl terminated neopentyl mercapto-alcohols and compositions therefrom Heteroatom containing perfluoroalkyl terminated neopentyl mercapto-alcohols of the formulas I and II HS--[CH2 C(CH2 X--E--Rf)2 CH2 ]--OH (I) HS--[CH2 C(CH2 X1 --Rf) | 09/08/1992 |
