Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 7902406 | Lubricating oil The present invention provides a lubricating oil comprising an alicyclic compound represented by a general formula (I): wherein n is an integer of 0 or 1; one of R1 and R2 repr... | 03/08/2011 |
| 7312187 | Polyalkylbicyclic derivatives Described are polyalkylbicylic chemical derivatives for use a fragrance ingredients having the generic structure: wherein m=0 or 1; wherein X is methyl or hydrogen; wherein R1, R2,... | 12/25/2007 |
| 7271294 | Cyclopropanecarboxaldehydes and their use in perfume compositions The present invention is directed to novel cyclopropanecarboxaldehyde compounds of the general formula wherein R is a straight, branched, or cyclic hydrocarbon moiety consisting of 6 to 30 carbon atoms and contai... | 09/18/2007 |
| 7161042 | Protected diols for prostaglandin synthesis A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralk... | 01/09/2007 |
| 7145043 | Non-Hazardous oxidative neutralization of aldehydes Methods, compositions, and devices for alleviating the problems of toxic discharge of aldehydes present in waste streams are disclosed. The methods relate to forming neutralized aldehydes by treating aldehydes with oxidizing agents. The oxidizing agents offer a simp... | 12/05/2006 |
| 7122706 | Process for preparing TCD-monenal A process for selectively hydroformylating dicyclopentadiene to 8(9)-formyltricyclo-[5.2.1.02,6]dec-3-ene in a heterogeneous reaction system using an aqueous solution of transition metal compounds, containing water-soluble organic phosphorus(III) compound... | 10/17/2006 |
| 7109371 | Prostaglandin synthesis A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralk... | 09/19/2006 |
| 7087796 | Cyclopropanecarboxaldehydes and their use in perfume compositions The present invention is directed to novel cyclopropanecarboxaldehyde compounds of the general formula wherein R is a straight, branched, or cyclic hydrocarbon moiety consisting of 1 to 3... | 08/08/2006 |
| 7074837 | Processes for preparation of bicyclic compounds and intermediates therefor A process for preparing intermediate compound (VII), compound (VIII) and compound (XIV) which will be raw materials for the synthesis of a synthetic antibactrial compound, via compound (I) or compound (X) and then, compound (II), the compounds each being shown below... | 07/11/2006 |
| 7060664 | Organic compounds Bicyclo[2.2.1]heptanes or heptenes mono-substituted at the 7-position with a substituent selected from the group consisting of linear or branched C2-10 alkyl or alkenyl, and alkylidene, and fragrance compositions containing same. ... | 06/13/2006 |
| 7019150 | 1-deoxy taxol analogs 1-Deoxybaccatin III, 1-deoxytaxol and 1-deoxy taxol analogs and method for the preparation thereof. ... | 03/28/2006 |
| 7015362 | Process for preparing TCD-dialdehyde A process for preparing 3(4),8(9)-bisformyltricyclo[5.2.1.02.6]decane by hydroformylating dicyclopentadiene with subsequent distillation wherein the hydroformylation of dicyclopentadiene is carried out in two stages, and, in the first hydroformylation sta... | 03/21/2006 |
| 6958395 | Method for producing water-soluble saccharide conjugates and saccharide mimetics by Diels-Alder reaction The present invention relates to a method by which saccharide compounds can be prepared in a very easy way. This method comprises the steps of: (a) attaching at least one saccharide to a cyclic or acyclic diene, (b) reacting the saccharide-... | 10/25/2005 |
| 6939997 | Process for preparing TCD-alcohol DM A process for preparing 3(4),8(9)-dihydroxymethyltricyclo[5.2.1.02,6]decane by hydroformylating dicyclopentadiene with subsequent distillation wherein the hydroformylation of dicyclopentadiene is carried out in two stages, and, in a first hydroformylation... | 09/06/2005 |
| 6677462 | Asymmetric synthesis of kavalactones This invention relates to preparation of enantio-enriched compounds, and more particularly to enantio-enriched kavalactone compounds and derivatives thereof. The methods provide compounds that are useful as reagents, or building blocks, in the constructio... | 01/13/2004 |
| 6534434 | Chiral imidazolidinone-based catalyst composition and reaction system Acid addition salts of imidazolidinones are provided as catalysts for transforming a functional group within a first reactant by reaction with a second reactant. Exemplary first reactants are ,ଲ-unsaturated carbonyl compounds such as ,... | 03/18/2003 |
| 6515137 | Catalytic processes employing chiral imidazolidinone-based catalyst composition Acid addition salts of imidazolidinones are provided as catalysts for transforming a functional group within a first reactant by reaction with a second reactant. Exemplary first reactants are ,ଲ-unsaturated carbonyl compounds such as ,... | 02/04/2003 |
| 6414167 | Octafluorotricyclodecane derivatives and processes for producing same The invention relates to a novel octafluorotricyclodecane derivative represented by the general formula (1), ##STR1## where R1 is a hydrogen atom, a halogen atom, a hydrocarbon group or a halogenated hydrocarbon group, m is 0 or 1, and R2 | 07/02/2002 |
| 6369243 | Chemical transformation of substrates using nonmetallic, organic catalyst compositions A method is provided for catalytically transforming a functional group within a first reactant by reaction with a second reactant in the presence of a nonmetallic, organic catalyst composition composed of a heteroatom-containing activator and an acid, or ... | 04/09/2002 |
| 6365782 | Production of tricyclodecane dicarbaldehyde, pentacyclopentadecane dicarbaldehyde and corresponding dimethanols A method of producing tricyclodecane dicarbaldehyde and/or pentacyclopentadecane dicarbaldehyde by the hydroformylation of dicyclopentadiene and/or tricyclopentadiene. The tricyclodecane dicarbaldehyde and/or pentacyclopentadecane dicarbaldehyde in the ... | 04/02/2002 |
| 6284929 | Odorants The invention relates to compounds of the general formula ##STR1## in which R1 to R7 are, independently, H, methyl or ethyl, R8 +R9 together form methylene (--CH2 --) or a single bond, or R1 | 09/04/2001 |
| 6271193 | Carbon containing functional group substituted 4,5,6,7-tetrahydro-polyalkylated-4-indanes, isomers thereof, processes for preparing same and uses thereof Described are carbon-containing functional groups substituted 4,5,6,7-tetrahydro-polyalkylated-4-indanes, isomers thereof, process for processes for preparing same, and uses thereof. The 4,5,6,7-tetrahydro-polyalkylated-4-indanes have the generic structur... | 08/07/2001 |
| 6242413 | Bicyclic aldehyde and ketone odorants The invention relates to bicyclic aldehydes and ketones of formula (I): ##STR1## wherein n is 1 or 2; R1 and R4 are independently H or CH3 ; and R2 and R3 are independently H, CH3 or CH2 C... | 06/05/2001 |
| 6235943 | Odorants The invention relates to compounds of the general formula ##STR1## in which R1 to R7 are, independently, H, methyl or ethyl, R8 +R9 together form methylene (--CH2 --) or a single bond, or R1 | 05/22/2001 |
| 6087296 | Raney iron catalyst and a process for hydrogenating organic compounds using said catalyst The present invention relates to a Raney catalyst comprising iron, cobalt, a third metal wherein the third metal is selected from the group consisting of nickel, rhodium, ruthenium, palladium, platinum, osmium, iridium and mixtures of any of these metals.... | 07/11/2000 |
| 5929291 | Odorants The invention relates to compounds of the general formula ##STR1## in which R1 to R7 are, independently, H, methyl or ethyl, R8 +R9 together form methylene (--CH2 --) or a single bond, or R1... | 07/27/1999 |
| 5886234 | Process for producing cyclic unsaturated aldehydes A process for producing a cyclic unsaturated aldehyde is herein disclosed which comprises the step of reacting a cyclic conjugated diene compound with an aldehyde represented by the general formula (I) R--CH.dbd.CH--CHO ... | 03/23/1999 |
| 5861385 | Substituted triols Substituted triols are prepared by reducing appropriately substituted carboxylic esters. The substituted triols can be used as active substances in medicaments.... | 01/19/1999 |
| 5597932 | Intermediate for the preparation of 19-nor vitamin D compounds The invention is drawn to a compound having the following formula ##STR1## in which X1 and X2, which may be the same or different, represent hydrogen or a hydroxy-protecting group, X4 is hydrogen, A is selected from -... | 01/28/1997 |
| 5525745 | Intermediates in the preparation of 19-nor vitamin D compounds The invention describes intermediates for use in the synthesis of 1-hydroxy-19-nor-vitamin D compounds. The intermediates have the following formula: ##STR1## The disclosed process includes (a) the construction of a 5,8-diol-6-yne interme... | 06/11/1996 |
| 5492887 | 8-exo-formyl-2,6-exo-tricyclo(5.2.1.02,6)decane, method of preparing it and use of the same It was found that 8-exo-formyl-2,6-exo-tricyclo[5.2.1.02,6 ]decane having the constitution and stereochemistry of formula (I) possesses particularly useful olfactory properties which are clearly superior to those of the 8-endo-epimer and which ... | 02/20/1996 |
| 5464866 | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases Substituted hydrindanes and their use in controlling angiogenesis-dependent diseases in warm blooded animals are disclosed.... | 11/07/1995 |
| 5367092 | Substituted 2,6-dimethylbicyclo[3,3,1]non-6-enes, processes for preparing same and organoleptic uses thereof Described are substituted 2,6-dimethylbicyclo[3,3,1]- non-6-enes defined according to the generic structure: ##STR1## wherein the dashed line represents a carbon-carbon single bond or a carbon-carbon double bond and wherein "R" represents one of the ... | 11/22/1994 |
| 5346884 | Substituted 2,6-dimethylbicyclo[3,3,1]non-6-enes, processes for preparing same and organoleptic uses thereof Described are substituted 2,6-dimethylbicyclo[3,3,1]-non-6-enes defined according to the generic structure: ##STR1## wherein the dashed line represents a carbon-carbon single bond or a carbon-carbon double bond and wherein "R" represents one of the m... | 09/13/1994 |
| 5235076 | Azulenic retinoid compounds, compositions and methods Novel azulenic retinoid compounds and therapeutic compositions are disclosed, along with method for their production and use as anti-cancer and cancer-prevention agents. The compositions of the present invention will also find use in treating dermatologic... | 08/10/1993 |
| 5039710 | Homocyclic derivatives Aphidicolane derivatives of the formula: ##STR1## wherein R1 stands for hydrogen or a hydroxy radical, R2 stands for a hydroxy or methyl radical, or the group CR1 R2 stands for a keto group; R3 s... | 08/13/1991 |
| 4992416 | Isomeric formyl trimethylbicyclo[2.2.2]oct-7-enes Isomeric formyl trimethylbicyclo[2.2.2]oct-7-enes, their use as perfumes, and a process for their preparation comprising a Diels-Alder reaction of acrolein with either 1,5,5-trimethylcyclohexa-1,3-diene, 3,5,5-trimethylcyclohexa-1,3-diene, 5,5-dimeth... | 02/12/1991 |
| 4983627 | Novel 6-alkyl and 6.8-dialkylbicyclo(4.2.0)octane derivatives Compounds useful in treating or preventing gastrointestinal ulcers and in treating cardiovascular disorders such as thrombosis, hypertension and atherosclerosis are depicted in formulas (1), (2) and (3): ##STR1## wherein: A is --C.tbd.C--, trans --HC... | 01/08/1991 |
| 4925956 | Novel process for manufacturing optically active carbacyclin intermediates The invention relates to a process for manufacturing optically active carbacyclin intermediate products from racemic cis-bicyclo[3.3.0]octane-2-carboxylic acids. This process makes it possible in an advantageous way to produce important intermediates for ... | 05/15/1990 |
| 4922027 | Process for the preparation of cycloaliphatic aldehydes The cycloaliphatic aldehydes of formula ##STR1## wherein R0, R1 and R2 represent independently a hydrogen atom or a lower alkyl from C1 to C6 and X stands for a group of formula ##STR2## ... | 05/01/1990 |
