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| Number | Title | Issue Date |
| 6528676 | Estrogenic compounds as anti-mitotic agents The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found belo... | 03/04/2003 |
| 6515137 | Catalytic processes employing chiral imidazolidinone-based catalyst composition Acid addition salts of imidazolidinones are provided as catalysts for transforming a functional group within a first reactant by reaction with a second reactant. Exemplary first reactants are ,ଲ-unsaturated carbonyl compounds such as ,... | 02/04/2003 |
| 6420610 | Silver halide photographic light-sensitive material, aromatic aldehyde derivative compound, and image-forming method Aromatic aldehyde compounds of formula (4) and (6) are disclosed, ##STR1## wherein Y is a methylene group with various substitutions and R represents various substituents.... | 07/16/2002 |
| 6369243 | Chemical transformation of substrates using nonmetallic, organic catalyst compositions A method is provided for catalytically transforming a functional group within a first reactant by reaction with a second reactant in the presence of a nonmetallic, organic catalyst composition composed of a heteroatom-containing activator and an acid, or ... | 04/09/2002 |
| 6342612 | Indane aldehydes and derivatives The present invention is directed to indanyl derivatives and the use of the indanyl derivatives in creating fragrances, and scents in items such as perfumes colognes and personal care products.... | 01/29/2002 |
| 6323173 | 2-indanmethanol derivatives and their use in perfumery The compounds of the formula ##STR1## wherein the symbols R1, R2, R3 and R4 represent, independently of one another, a hydrogen atom or a linear or branched, saturated or unsaturated C1 to C3 | 11/27/2001 |
| 6288290 | Method for production of halogen-containing aromatic compound This invention relates to a method for the production of an aromatic compound (II) having a (CH2)n CX2 Br group (wherein X represents a fluorine or chlorine atom and the X's may be same or different, and n is an integer in... | 09/11/2001 |
| 6271411 | Process for preparing 2-aryl-substituted indenes A process is disclosed for preparing 2-aryl-substituted indenes by reacting an indene with an arene compound substituted with an halogen atom, preferably a iodine atom, or with an organosulphonate group, said reaction being carried out in a basic medium i... | 08/07/2001 |
| 6147224 | 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors Compounds of Formula 1, Formula 2 or Formula 3 where X is O, S, or (CR1 R1)n where n is 0, 1 or 2; Y is a bivalent radical having Formula 4 or Formula 5 where o is an integer from 1 to 4 ##STR1## or Y is a bivalent ar... | 11/14/2000 |
| 6103688 | Aromatic compounds, processes for their preparation and their use in perfumery Compounds consisting of indan derivatives of the formula: ##STR1## Wherein X or Y represents an aldehyde or an acetal group and the other represents a hydrogen, and R represents a hydrogen or a methyl group and the t-butyl group is at the 5 or 6 posi... | 08/15/2000 |
| 6043397 | Method for production of fluorine-containing aromatic compounds A method for the production of a fluorine-containing aromatic compound is provided which allows the relevant reaction to proceed in a standard reaction vessel such as, for example, a glass vessel at room temperature under an ambient pressure without requi... | 03/28/2000 |
| 5907069 | Production of nabumetone or precursors thereof In producing nabumetone or precursor thereof, use is made of 2-bromo-6-methoxynaphthalene formed by (a) methylating 6-bromo-2-naphthol with methyl bromide or methyl chloride, in a halogen-free liquid solvent comprising at least about 40% by weight of one ... | 05/25/1999 |
| 5861385 | Substituted triols Substituted triols are prepared by reducing appropriately substituted carboxylic esters. The substituted triols can be used as active substances in medicaments.... | 01/19/1999 |
| 5780675 | Deoxygossylic compounds The invention provides deoxygossylic compounds having useful biological activities, and methods for the synthesis of these and related compounds. The invention further provides valuable intermediates for the synthesis of the compounds, and pharmaceutical ... | 07/14/1998 |
| 5766610 | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active polycyclic aromatic compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(e): ##STR2## and are useful for the treatment of a wide variety of disease... | 06/16/1998 |
| 5716624 | Polyaromatic propynyl compounds and pharmaceutical/cosmetic compositions comprised thereof Novel pharmaceutically/cosmetically-active polyaromatic propynyl compounds have the structural formula (1): ##STR1## in which X is one of the radicals: ##STR2## and are useful for the treatment of a wide variety of disease states, whether h... | 02/10/1998 |
| 5574190 | Naphthyl compounds, intermediates, compositions, and methods The present invention provides pharmaceutically active compounds formula I ##STR1## wherein R1 is --H, --OH, --O(C1 -C4 alkyl), --OCOC6 H5, --OCO(C1 -C6 alkyl), or --OSO2 | 11/12/1996 |
| 5552379 | Aromatic compounds, processes for their preparation and their use in perfumery The compounds of formula a. ##STR1## wherein symbol X represents a --CHO group or a group of formula ##STR2## in which symbols R', taken separately, represent each a C1 to C4, linear or branched, saturated or unsaturated ... | 09/03/1996 |
| 5521151 | Tetralinic nitriles, their use as perfuming ingredients and aldehyde intermediates for their preparation We disclose a novel nitrile, i.e. 5,6,7,8-tetrahydro-3,5,5,6,7,8,8-heptamethyl-2-naphthalenecarbonitrile, a perfuming ingredient having a musky, earthy odor, and which is remarkably stable in particularly aggressive media such as for instance antiper... | 05/28/1996 |
| 5514825 | Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity Compounds of the formula ##STR1## wherein R1 is hydrogen or alkyl of 1 to 10 carbons; R2 and R3 are hydrogen, or alkyl of 1 to 6 carbons and the substituted ethynyl group occupies either the 2 or the 3 position of the... | 05/07/1996 |
| 5470999 | Cyclohexene and bicyclic aromatic substituted ethyne compounds having retinoid-like biological activity Compounds of Formula 1 ##STR1## where R1 -R5 are hydrogen, lower alkyl of 1-6 carbons, or halogen; A is (CH2)n where n is 0-5, lower branched chain alkyl having 3-6 carbons, cycloalkyl having 3-6 carbons, a... | 11/28/1995 |
| 5457239 | Process for formylation of aromatic compounds A process for the preparation of a formylated aromatic compound comprising contacting an aromatic compound with (i) a halogenated compound in the presence of a Lewis acid, and (ii) a base, is described. The subject process provides an efficient and effect... | 10/10/1995 |
| 5455265 | Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors Process of treatment of mammals, including humans to treat diseases or conditions of the type which are normally treated with retinoid-like compounds is disclosed, with pharmaceutical compositions containing an active compound which is a selective agonist... | 10/03/1995 |
| 5403823 | Alkyl indane aldehyde compounds The present invention relates, inter alia, to novel alkyl indane aldehyde compounds having fragrant musk-like aroma.... | 04/04/1995 |
| 5401720 | Alkyl tetralin aldehyde compounds The present invention relates, inter alia, to novel alkyl tetralin aldehyde compounds having fragrant musk-like aroma.... | 03/28/1995 |
| 5278338 | Racemization process for optically active carboxylic acids, salts and esters A method for racemizing an optically active carboxylic acid, or ester thereof, of the formula: ##STR1## where R1 is hydrogen, hydroxy, halo, cyano, C1 to C6 linear or branched alkoxy, amino or substituted amino or the... | 01/11/1994 |
| 5227367 | Oxypentamethylindane carboxaldehydes, methods for preparing same, organoleptic uses thereof and cosmetic and pharmaceutical compositions containing them Described are oxypentamethylindane carboxaldehydes defined according to the generic structure: ##STR1## wherein R' represents a hydrogen or methyl, methods for preparing same, organoleptic uses thereof and cosmetic and pharmaceutical compositions ... | 07/13/1993 |
| 5206217 | Indane compounds and compositions The present invention relates to novel indane compounds, such as, for example, 5-formyl-1,1,2,3,3,4,6-heptamethylindane, a compound of the formula ##STR1## and to compositions including the same, as well as to methods for their preparation. Comp... | 04/27/1993 |
| 5169974 | Process for manufacturing aryloxyaldehydes The invention concerns a novel process for the manufacture of various aryloxyaliphatic aldehydes and related arylthio analogues, which are useful as chemical intermediates. The process involves reacting a dihalogenohydroxyalkane of the formula: HO.C(R | 12/08/1992 |
| 5162588 | Aromatic compounds, a process for preparation thereof and use of same as perfuming ingredients Compound of formula ##STR1## wherein a) indexes m and n are identical and stand each for an integer number equal to zero, symbols R1 and R2 are identical and represent each a hydrogen atom, or are different and represent each a ... | 11/10/1992 |
| 5128479 | Oxidized diphenylheteroalkanes Oxidized diphenylheteroalkanes of the formula I ##STR1## where R1 to R6 and A have the meanings specified in the description, and the preparation thereof are described. The substances are suitable for controlling diseases and as... | 07/07/1992 |
| 5095152 | Novel heptamethyl indane compound The present invention relates to a novel indane compound which is 5-formyl-1,1,2,3,3,4,6-heptamethylindane, a compound of the formula ##STR1##... | 03/10/1992 |
| 5026726 | Gossylic iminolactones and gossylic lactones and their anti-viral activities A compound of the chemical formula ##STR1## wherein n is 1 or 2, X is NH and O, and R1 and R2 are H, (C1 -C12) alkyl, (C2 -C12)alkenyl, (C2 -C12)alkynyl, (C2... | 06/25/1991 |
| 4950796 | Novel benzaldehydes Novel benzonitriles, benzaldehydes and benzyl alcohols of the formula I ##STR1## where R1 is methyl or ethyl, R2 is alkyl, alkenyl, cycloalkyl, cycloalkenyl, bicycloalkyl, bicycloalkenyl, or C1 -C5 -alkyl-s... | 08/21/1990 |
| 4723042 | Alpha,beta-substituted acroleins and their preparation Alpha,beta-substituted acroleins of the general formula I ##STR1## where A and B are identical or different and are each C1 -C4 -alkyl, naphthyl, biphenyl or phenyl which may be monosubstituted or polysubstituted by halogen, nit... | 02/02/1988 |
| 4723022 | Substituted 2,3-naphthalenedicarboxaldehydes A new class of substituted 2,3-naphthalenedicarboxaldehydes (NDA) is disclosed. Such compounds are of the formula: ##STR1## wherein one or more of R1 -R8 are various substituting groups. The above compounds react, in the presenc... | 02/02/1988 |
| 4581380 | 2,6-disubstituted naphthalene derivatives, a process for preparing the same and pharmaceutical and cosmetic compositions containing the same New 2,6-disubstituted derivatives of naphthalene have the formula ##STR1## wherein n is 1 or 2, R1 to R4 are hydrogen or CH3, R5 is ##STR2## (iv) 2-oxazolinyl, wherein m is 0 or 1, R6 is hydrogen... | 04/08/1986 |
| 4456618 | Naphthenic and heterocyclic retinoic acid analogues Naphthenic and heterocyclic retinoic acid analogues such as (E)-6-[2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-2-naphthaldehyde, methyl 6-[2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-2-naphthoate, 6-[2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-2-nap... | 06/26/1984 |
| 4395571 | Process for the preparation of d,1-2-(6-methoxy-2-naphthyl)propionic acid Racemic mixtures of d,1-2-(6-methoxy-2-naphthyl)propanal are resolved by forming a condensation product with N-R-D-glucamine or a salt thereof where R is hydrogen, alkyl of 1 to 36 carbon atoms or cycloalkyl of 3 to 8 carbon atoms, from which a product su... | 07/26/1983 |
| 4374293 | Indene production from aromatic olefins Allylbenzene is converted to indene by means of a tungsten-containing catalyst.... | 02/15/1983 |
