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| Number | Title | Issue Date |
| RE43280 | Hyperforin derivatives, the use thereof and formulations containing them The use of the reduction products of hyperforin and adhyperforin, pharmaceutically acceptable salts or esters thereof, in the pharmaceutical and/or nutritional field, in particular in the treatment of depression and Alzheimer's disease. ... | 03/27/2012 |
| 7943800 | Migrastatin analogs and uses thereof The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of various disorders including cancer, metastasis and disorders involving... | 05/17/2011 |
| 7402712 | Adamantyl vinyl ether compound and production process for the same Provided by the present invention are an adamantyl vinyl ether compound which is useful as a monomer for functional resins in the photolithography field or a raw material therefor and medical and agricultural intermediates and a production process for the same. ... | 07/22/2008 |
| 7282612 | Method for producing monocyclic ketones C-C The invention relates to a method for producing monocyclic ketones C4-C5. The inventive method is based on the reaction of a liquid-phase oxidation of monocyclic alkenes C4-C5 into corresponding cyclic ketones by nitrogen ... | 10/16/2007 |
| 7247753 | Method for producing macrocyclic ketones by means of dieckmann codensation in the gas phase The invention relates to a method for producing macrocyclic ketones of general formula (I) by direct cyclisation of compounds of general formula (II) in the gas phase on a heterogeneous catalyst. In general formula (I), X represents a monounsaturated or polyunsatura... | 07/24/2007 |
| 7199161 | Substituted bicylo[3.3.1]nonan-2,4,9-triones as pharmaceutical active ingredients The invention relates to the use of substituted bicyclo[3.3.1]nonan-2,4,9-triones, especially clusianon and clusianon derivatives, as pharmaceutical active ingredients or medicamentous active ingredients, especially for producing medicaments for the prophylactic and... | 04/03/2007 |
| 7135501 | Clusianon isomers and use thereof The invention relates to a clusianon isomer and to the use thereof, in particular as a pharmaceutical or medical active ingredient, in particular for producing medicaments for the prophylactic and/or therapeutic (curative) treatment of tumor or cancer diseases as we... | 11/14/2006 |
| 7129380 | (Z)-7-cyclohexadecen-1-one as an odorant The compound (Z)-7-cyclohexadecen-1-one is described as a musk odorant. Also described are odorant or aroma mixtures comprising (Z)-7-cyclohexadecen-1-one and one or more other odorants or aromas. ... | 10/31/2006 |
| 7105705 | Hyperforin derivatives, the use thereof and formulations containing them The use of the reduction products of hyperforin and adhyperforin, pharmaceutically acceptable salts or esters thereof, in the pharmaceutical and/or nutritional field, in particular in the treatment of depression and Alzheimer's disease. ... | 09/12/2006 |
| 7105704 | Method for producing monocyclic ketones C-C The invention relates to a method for producing monocyclic ketones C7–C20. The method of patent protection sought is based on the oxidation reaction of monocyclic alkenes C7–C20 into corresponding monocyclic ket... | 09/12/2006 |
| 7087793 | Process for producing cycloalkanol and/or cycloalkanone The present invention provides a process for producing cycloalkanol and/or cycloalkanone by oxidizing cycloalkane with molecular oxygen in the presence of a heteropolyacid compound comprising a cobalt atom as a central element and a cobalt atom as a frame element. | 08/08/2006 |
| 7057078 | Hyperforin halogenated derivatives, the use thereof and formulations containing them Hyperforin and adhyperforin halogenated derivatives of general formula (I) in which X, R and R1 have the meanings as defined in the disclosure, the process for the preparation thereof and the use thereof in the pharmaceutical and/or nutritional field, in ... | 06/06/2006 |
| 7034188 | Production method of ketone compound A method for producing a ketone, particularly a macrocyclic ketone, from a 2-hydroxycycloalkanone having from 12 to 18 carbon atoms by efficiently dehydrating and reducing the acyloin in a single reaction vessel. A method for producing a ketone compound, which compr... | 04/25/2006 |
| 7019175 | Catalytic oxidation process The invention provides a process for the catalytic oxidation of an alkane, which comprises contacting the alkane with a source of oxygen in the presence of a catalyst comprising a compound of the formula (2) where R1 and R2 independently repres... | 03/28/2006 |
| 6951964 | Method for producing macrocyclic ketones The present invention relates to a novel thermo-isomerization method for rapidly and simply producing macrocyclic ketones of the formula Ia or Ib. The macrocyclic ketones are prepared in the gas phase at temperatures abo... | 10/04/2005 |
| 6930209 | Liquid phase oxidation of cycloalkane compound A method for liquid phase oxidation of a cycloalkane compound is provided by which the cycloalkane compound intended to be oxidized mixes with water to form an azeotropic mixture, and then an oxygen enriched gas is introduced to perform an oxidation reaction. This m... | 08/16/2005 |
| 6924398 | Substituted tropolone compounds, oral care compositions containing the same and methods of using the same The present invention relates to novel tropolone compounds of the present invention and to oral care compositions suitable for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, comprising an oral care effectiv... | 08/02/2005 |
| 6861563 | Process for preparation of cyclododecanone In the process for producing a cyclododecanone by isomerizing an epoxycyclododecane-containing starting material in the presence of an isomerization reaction catalyst containing lithium bromide and/or lithium iodide, in order to perform the reaction with high effici... | 03/01/2005 |
| 6855831 | Process for the preparation of cyclic diketones The present invention relates to a process for the preparation of compounds of formula I: wherein the substituents are as defined in claim 1, by conversion of a compound of formula II: | 02/15/2005 |
| 6787675 | Substituted tropolone compounds, oral care compositions containing the same and methods of using the same The present invention relates to novel tropolone compounds of the present invention and to oral care compositions suitable for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, comprising an oral care effectiv... | 09/07/2004 |
| 6759557 | Melanin production inhibitors and skincare products containing such inhibitors A melanin synthesis inhibitor composition containing at least one macrocyclic compound represented by Formula (1) wherein X is a group selected among the groups consisting of C═O; CH—OH and O═C—CHOH; R being a ch... | 07/06/2004 |
| 6753448 | Photoresist monomers, polymers thereof and photoresist compositions using the same The present invention provides compounds represented by formulas 1a and 1b′; and photoresist polymers derived from the same. The present inventors have found that photoresist polymers derived from compounds of formulas 1a, 1b, or mixtures thereof, having an acid l... | 06/22/2004 |
| 6720303 | Macrocyclic musk composition, organoleptic uses thereof and process for preparing same Described are mixtures consisting essentially of oxomacrocyclic compounds containing greater than about 40 weight % Δ3-cyclotetradecen-1-one and greater than about 40 weight % cyclotetradecanone and less than about 5 weight %, of Δ2-cyclo-tet... | 04/13/2004 |
| 6686483 | Catalytic asymmetric epoxidation The present invention provides a variety of methods that are based on stereoselective epoxidation of an olefin by an epoxidizing agent derived from a reaction between an oxidizing agent and a chiral ketone. For example, present invention provides methods ... | 02/03/2004 |
| 6630609 | Taxane synthesis method and intermediates A process for the preparation of a composition having the formula: ##STR1## in which a compound having the formula: ##STR2## is treated with a base and a silylating agent.... | 10/07/2003 |
| 6551988 | Fragrance compounds 4,8-cyclododecadienyl ketones having formula (I), in which R has up to 5 carbon atoms, are novel compounds exhibiting woody/amber odor characteristics which find use in perfumes and in perfumed products. ##STR1##... | 04/22/2003 |
| 6326349 | Methylcyclotetradec-5-en-1-ones Disclosed are compounds of formula I having a strong musk-like odor: ##STR1## In formula I, R1 and R2 are hydrogen or methyl, with the proviso that when R1 is methyl, R2 is hydrogen, and when R1 is hy... | 12/04/2001 |
| 6303836 | Method for producing 2-cyclododecyl-1-propanol 2-Cyclododecyl-propanol [sic], which is in demand as musk scent, is prepared in an advantageous industrial process by reacting cyclododecene with an excess of propionic acid or of a propionic acid derivative in the presence of catalytic amounts of a free-... | 10/16/2001 |
| 6287749 | Biradical photoinitiators and photopolymerizable compositions Biradical initiators and methods using the same are disclosed. Polymerization of compositions which include the compounds of the invention may be activated by irradiating the composition with radiation.... | 09/11/2001 |
| 6278027 | 3-Substituted-2-halocycloheptenone compounds and a method for manufacturing same The present invention relates to compounds of formula (1). ##STR1## wherein: R1 is hydrogen atom or lower alkyl group, X is bromine atom or chlorine atom; and which are useful for the preparation of the cycloheptanoides such as cycloheptimidazo... | 08/21/2001 |
| 6278026 | Intermediates for tricyclic or tetracyclic taxanes The synthesis of taxol and other tricyclic and tetracyclic taxanes.... | 08/21/2001 |
| 6242413 | Bicyclic aldehyde and ketone odorants The invention relates to bicyclic aldehydes and ketones of formula (I): ##STR1## wherein n is 1 or 2; R1 and R4 are independently H or CH3 ; and R2 and R3 are independently H, CH3 or CH2 C... | 06/05/2001 |
| 6204416 | Method for the transformation of cis- and trans-cyclododecene oxide into cyclododecanone A method for the transformation of cis- and trans-cyclododecene oxide into cyclododecanone, comprising carrying out the reaction with catalytically activated hydrogen in the presence of a copper catalyst at a temperature of 150-260° C. and at a pressure ... | 03/20/2001 |
| 6200254 | Macrocyclic ketones as fragrance materials and methods for making same Novel macrocyclic diene ketone compounds useful as fragrance materials are described having the following general formula (I): ##STR1## where R1, R2, R3 and R4 are each either a hydrogen atom or a C1 ... | 03/13/2001 |
| 6184419 | , ଲ-unsaturated ketones The present invention relates to new ,ଲ-unsaturated ketones of formula I. The new compounds exhibit an intense, very long lasting green galbanum-type odor with fruity undertones. Compositions containing these novel compounds are also provided... | 02/06/2001 |
| 6169211 | Process and apparatus for production of 5-cyclohexadecen-1-one Disclosed is a process for producing 5-cyclohexadecen-1-one continuously from 1,2-divinylcyclododecanol in a short time in an efficient manner without side reactions. In the process, 1,2-divinylcyclododecanol as a starting material is supplied from a raw ... | 01/02/2001 |
| 6150374 | Substituted cycloalkenes, process of preparing them and method of using them as pesticides The invention relates to novel substituted cycloalkenes of the formula (I), ##STR1## to a plurality of processes for their preparation, and to novel intermediates and a plurality of processes for their preparation.... | 11/21/2000 |
| 6111144 | Method for the synthesis of a taxane intermediate A process for the preparation of a compound having the formula: ##STR1## in which a compound having the formula: ##STR2## is treated with a base and a silylating agent.... | 08/29/2000 |
| 5936100 | Synthesis of functionalized macrocycles by ring closing metathesis The invention concerns an improved process for the preparation of macrocyclic products with 12 or more ring atoms containing one or more polar functional groups on the ring and/or one or more heteroatoms within the ring by ring closing metathesis (RCM) of... | 08/10/1999 |
| 5466827 | Use of thioalkanediones as aroma substances Thioalkane ,ଲ-diketones have interesting organoleptic properties and are therefore suitable as aroma substances.... | 11/14/1995 |
