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| Number | Title | Issue Date |
| 7419943 | Methanoazuenofurans and methanoazulenone compounds and uses of these compounds as fragrance materials The use of novel methanoazulenofuran and methanoazulenone compounds for use as fragrance chemicals, suitable for use incorporated in a wide variety of products such as perfumes, colognes and personal care products having a structure ... | 09/02/2008 |
| 7247754 | Method for the production of trimeric ketone peroxide solutions Cyclohexane is reacted with hydrogen peroxide in the presence of nitric acid which is used as a catalyst in a suitable solvent for the production of trimeric cyclohexane peroxide. ... | 07/24/2007 |
| 7141603 | Antitumor agents The present invention provides compounds of general formula I or II: wherein R1, R2, R3, R4, R5, R6, and R7 have any of the values defi... | 11/28/2006 |
| 7019150 | 1-deoxy taxol analogs 1-Deoxybaccatin III, 1-deoxytaxol and 1-deoxy taxol analogs and method for the preparation thereof. ... | 03/28/2006 |
| 6982354 | Preparation of ketone containing cyclic compounds A method of preparing a polycyclic compound containing a ketone functionality comprising: reacting a mixture comprising a catalyst, a reactant compound and an amount of water greater than or equal to 3 weight percent (wt %) based o... | 01/03/2006 |
| 6908918 | Antitumor agents The present invention provides compounds of general formula I or II: wherein R1, R2, R3, R4, R5, R6, and R7 have any of the values defined in... | 06/21/2005 |
| 6717017 | Total synthesis of antitumor acylfulvenes The present invention provides a method of synthesizing compounds of formula (I) or (II): wherein R1 is hydrogen, R′ is (C1-C4)alkyl and X is a hydroxyl protecting group. ... | 04/06/2004 |
| 6545186 | Process for the purification of ketones obtained from the corresponding terpenes by ozonolysis and reduction Improved, safe process for the purification of ketones obtained by ozonolysis and subsequent reduction of the corresponding terpenes, in which, after the ozonolysis and reduction of acyclic mono-, bi- or tricyclic terpenes with ozonizable double bonds, co... | 04/08/2003 |
| 6344590 | Adamantanemethanol derivatives and production processes thereof An adamantanemethanol derivative of the invention is represented by the following formula (1), wherein Ra is a hydrogen atom or a hydrocarbon group; Rb is a hydrocarbon group having a carbon atom, to which carbon atom at least one hy... | 02/05/2002 |
| 6340774 | Non-steroidal estrogen-receptor antagonists This invention relates generally to non-steroidal estrogen-receptor (ER) antagonists that are useful as therapeutics in the treatment of advanced stage breast cancer. More particularly, this invention relates to the cloning and heterologous expression of ... | 01/22/2002 |
| 6313353 | Method for producing an optically active acyloin By treating the reactant of 3,4-ditrimethylsilyloxytricyclo[4.2.1.02.5 ]nona-3,7-diene and binaphthol monoether-tin tetrachloride complex, optically active acyloin is produced. Using the optically active acyloin compound as a starting material,... | 11/06/2001 |
| 5968482 | -hydroxyketoalkyl derivatives as light protection filters The invention relates to the use of -hydroxyketoalkyl derivatives as light protection filters for cosmetic or pharmaceutical products, the -hydroxyketoalkyl group being linked, if appropriate via a spacer, to a chromophoric group which has a... | 10/19/1999 |
| 5639883 | Process for preparing substituted 4-methylidenecinnamic acid derivatives A process for preparing substituted 4-methylidenecinnamic acid derivatives of Formula (I). ##STR1## The variables are defined herein. The compounds of Formula (I) can be used, for example, as UV absorbers.... | 06/17/1997 |
| 5628988 | Ketotricyclo[5.2.1.0]decane derivatives The invention relates to ketotricyclo[5.2.1.0]decane derivatives of the formula I ##STR1## wherein Phe is a phenyl group which is unsubstituted or substituted by 1 to 5 hydroxyl, alkyl or alkoxy groups having 1 to 10 C atoms, and their preparation an... | 05/13/1997 |
| 5600007 | Use of -hydroxyketoalkyl derivatives as light protection filters The invention relates to the use of -hydroxyketoalkyl derivatives as light protection filters for cosmetic or pharmaceutical products, the -hydroxyketoalkyl group being linked, if appropriate via a spacer, to a chromophoric group which has a... | 02/04/1997 |
| 5576355 | Diamondoid derivatives for pharmaceutical use A method of inhibiting viruses in which a virus is contacted with diamondoid alcohol, ketone, ketone derivative, adamantyl amino acid, quaternary salt or combinations thereof which have antiviral properties. These diamondoid derivatives are shown to have ... | 11/19/1996 |
| 5538944 | Composition containing a preponderant amount of (1RS,5RS)-5-methyl-exo-tricyclo[6.2.1.02,7]undecan-4-one and its use in perfumery (1RS,5RS)-5-Methyl-exo-tricyclo[6.2.1.02,7 ]undecan-4-one, as well as the compositions which contain a preponderant amount of this compound together with its isomer (1RS,5SR)-5-methyl-exo-tricyclo[6.2.1.02,7 ]undecan-4-one, are usefu... | 07/23/1996 |
| 5442098 | Cyclohexene diol derivatives The present invention relates to optically active cyclohexene diol derivatives and optically active cyclohexenone derivatives, and a process for production of these compounds in which a special cyclohexene diol of a starting material is reacted by selecti... | 08/15/1995 |
| 5437686 | Peroxygen bleach composition activated by bi and tricyclic diketones Bleaching compositions comprising an inorganic peroxygen compound and a bicyclic or tricyclic diketone as an activator for the peroxygen compound. The composition preferably comprises about 1 to about 75% of the peroxygen bleaching compound and about 1 to... | 08/01/1995 |
| 5434274 | Benz(epsilon)indene compounds Neuroactive benz[e]indene compounds ##STR1## are prepared by a total synthesis from the following three starting materials ##STR2##... | 07/18/1995 |
| 5346885 | Polycyclic compounds and their use as perfuming ingredients The compounds of formula ##STR1## wherein symbol X designates a C.dbd.O (Ia) or C(CH3)--OC(O)CH3 (Ib) group and the dotted line indicates the location of a single or double bond in formula (Ia) and of a double bond in formula (I... | 09/13/1994 |
| 5206415 | Tricyclic steroid analogs Novel tricyclic steriod analogs are disclosed which are 1H-benz[e]indene dodecahydro compounds that are useful for enhancing GABA-induced chloride currents at the GABA receptor/chloride ionophore complex and can be represented by the following structural ... | 04/27/1993 |
| 5158981 | Antiandrogenic compounds and methods A antiandrogenic compositions comprising an anti-androgenically effective amount of at least one compound of the formula ##STR1## wherein R is alkyl of 1 to 4 carbon atoms, R1 is alkyl of 1 to 2 carbon atoms, R2 is selected from... | 10/27/1992 |
| 5151411 | Tricyclic ketones and fragrance compositions containing same A compound of the formula ##STR1## wherein the dotted line signifies an optional bond, as racemates or individual enantiomers, odorant compositions containing the same, and a process for the manufacture of the compounds of formula I which comprises ... | 09/29/1992 |
| 5015761 | Tricyclo{6.2.1.01,6 }undecanes useful as fragrance chemicals Novel tricycloundecanones are disclosed having the general formula ##STR1## wherein R1, R2, and R3 are hydrogen or 1 to 3 carbon alkyl groups having a total carbon number of six or less. These compounds are useful per... | 05/14/1991 |
| 4947002 | Novel tricyclic ketones and fragrance compositions containing same Novel compounds of the formula ##STR1## wherein: the symbols R1, R2, R4, R5 and R6 represent hydrogen or methyl, with the proviso that only one of R1, R2 and R4 r... | 08/07/1990 |
| 4927975 | Process for preparing certain decahydro-7H-3-ol-7-ones Novel antiandrogenic compositions comprising an antiandrogenically effective amount of at least one compound of the formula ##STR1## wherein R is alkyl of 1 to 4 carbon atoms, R1 is alkyl of 1 to 2 carbon atoms, R2 is selected f... | 05/22/1990 |
| 4876399 | Taxols, their preparation and intermediates thereof The present invention is directed to novel taxols useful as a chemotherapeutic agent. Moreover, the present invention is directed to the process of preparing taxols and various intermediates in said process. A key intermediate is this process is 2,5-dihyd... | 10/24/1989 |
| 4874890 | Process for the production of deuterated methyl acrylate or deuterated methyl methacrylate There is provided the improved process for the production of deutrated methyl acrylate or methacrylate by the direct substitution of deuterium for hydrogens in methyl acrylate or methacrylate in the presence of a platinum Group metal catalyst.... | 10/17/1989 |
| 4874891 | Open "D" ring hormone analogs Compounds of the formula: ##STR1## and the pharmaceutically acceptable esters thereof, wherein rings A and B are selected from the group consisting of ##STR2## wherein x represents an aromatic ring, or the presence or absence of 0, 1, or ... | 10/17/1989 |
| 4849454 | Benzindenolones as antiandrogenic agents Novel antiandrogenic compositions comprising an anti-androgenically effective amount of at least one compound of the formula ##STR1## wherein R is alkyl of 1 to 4 carbon atoms, R1 is alkyl of 1 to 2 carbon atoms, R2 is selected ... | 07/18/1989 |
| 4762819 | 2,6-exo configured tricyclo-5.2.1.02,6 decane derivatives with functional side chains at C-8/C-9 and their utilization thereof as perfumes The invention relates to 2,6-exo-configured tricyclo-5.2.1.02,6 decane derivatives that correspond to general formula A wherein ##STR1## Ra, Rb, Rc, Rd are hydrogen or Rd is a methyl g... | 08/09/1988 |
| 4756764 | Tricylic ketone and use of same as flavoring ingredient 3,10-Diacetyl-11-isopropylidene-7,7-dimethyl-tricyclo[6.2.1.02,6 ]undeca-2,5,9-triene is a flavoring ingredient useful for the aromatization of smoking articles. It develops upon smoking green, slightly floral, metallic, astringent, fatty, slig... | 07/12/1988 |
| 4607054 | Antiandrogenic compositions containing indene-7-ones Novel antiandrogenic compositions comprising an antiandrogenically effective amount of at least one compound of the formula ##STR1## wherein R is alkyl of 1 to 4 carbon atoms, R1 is alkyl of 1 to 2 carbon atoms, R2 is selected f... | 08/19/1986 |
| 4603223 | Process for the manufacture of quinone derivatives A novel process for the manufacture of quinone derivatives is described. In this process a compound of the formula ##STR1## is reacted with a compound of the formula ##STR2## and the resulting compound of the formula ##STR3## is subjected t... | 07/29/1986 |
| 4466971 | Certain decahydro-7H-benz(e)-inden-7-ones, compositions containing same and method of use Novel antiandrogenic compositions comprising an antiandrogenically effective amount of at least one compound of the formula ##STR1## wherein R is alkyl of 1 to 4 carbon atoms, R1 is alkyl of 1 to 2 carbon atoms, R2 is selected f... | 08/21/1984 |
| 4453014 | Perfume compositions and perfumed articles containing one or more tetramethyl-tri-cycloundecyl-alkyl ketones as perfume base Perfume compositions, perfumed materials and perfumed articles containing one or more isomers of substituted 1.4.4.8-tetramethyl-tricyclo[6.3.0.02.5 ]-undecanes as perfume base. Use of one or more isomers of 9-alkanoyl-1.4.4.8-tetramethyl-tricy... | 06/05/1984 |
| 4415756 | Pure enantiomers of bicyclo[2.2.2]oct-5-en-2-ones, processes for their production and their use New bicyclo[2.2.2]oct-5-en-2-ones of the formulae Ia and Ib in the form of pure enantiomers and processes for preparing them are described. The compounds are used for the preparation of pure enantiomers of the formula V by sensitized photoreaction or of c... | 11/15/1983 |
| 4390721 | 3-Endo-protected hydroxyl-tricyclo[3,2,0,02,7 ]heptan-6-ones A novel 3-endo-protected hydroxyl-tricyclo[3,2,0,02,7 ]heptan-6-one is described which can be alkylated stereospecifically to give a 5-endo-protected hydroxyl-bicyclo[2,2,1]heptan-2-one which may then be converted via a sequence of reactions in... | 06/28/1983 |
| 4373108 | Bridged tricyclic alcohol, process for preparing same and perfumery use thereof Described are the compounds covered by the generic structure: ##STR1## wherein "R" represents hydrogen or lithium. The compound having the structure: ##STR2## is useful in augmenting or enhancing the patchouli aroma of a perfume, cologne or... | 02/08/1983 |