Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7456321 | Process for producing high-purity 4,4′-dihydroxydiphenyl sulfone The present invention provides a process for producing 4,4′-dihydroxydiphenylsulfone of very high purity. In particular, the present invention provides a process for producing 4,4′-dihydroxydiphenylsulfone of high purity comprising the steps of subjecting phenol... | 11/25/2008 |
| 7411004 | Sulphones which modulate the action of gamma secretase Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease. ... | 08/12/2008 |
| 7402704 | Arylsulfones and uses related thereto Aryl sulfone compounds of formula I and II are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders: ... | 07/22/2008 |
| 7250536 | Process for the isomerisation of a cyclohexenyl alkyl or alkenyl ketone The present invention relates to a process for the carbon-carbon double bond isomerisation of a 2-alkyl-cyclohex-3-enyl alkyl or alkenyl ketone into a mixture comprising the corresponding 2-alkyl-cyclohex-2-enyl ketones and the corresponding 2-alkylene-cyclohexyl ke... | 07/31/2007 |
| 7241924 | Industrial process for the production of diphenyl sulfone compounds A process for producing 4-isopropoxy-4′-hydroxydiphenyl sulfone useful as the developer for leuco dyes to be used in thermosensible papers, which is excellent in productivity, economical efficiency and safety and permits the production of the compounds from consta... | 07/10/2007 |
| 7217492 | Onium salt compound and radiation-sensitive resin composition An onium salt compound having a cation moiety of the following formula (1) is disclosed. wherein A represents I or S, m is 1 or 2, n is 0 or 1, x is 1–10, and Ar1 and Ar2 are (substituted) aromatic hydrocarbon ... | 05/15/2007 |
| 7217841 | Stabilizers and antiozonants for elastomers Elastomers which have excellent stability to prevent oxidative, thermal, dynamic, light-induced and/or ozone-induced degradation comprise, as stabilizers, at least one compound of the formula I [R—S(═O)m—CH2—CH(OH)—CH2 | 05/15/2007 |
| 7193113 | Arylbis(perfluoroalkylsulfonyl) methane and metallic salt thereof, and methods for producing the same The present invention provides a method for producing various types of arylbis(perfluoroalkylsulfonyl)methane having a bulky aryl group and an electron-accepting aryl group in which synthesis was conventionally considered to be difficult, at high efficiency; a novel... | 03/20/2007 |
| 7189880 | Process for producing 2,4′-dihydroxydiphenylsulfone A process for producing 2,4′-dihydroxydiphenylsulfone which comprises separating 4,4′-dihydroxydiphenylsulfone by crystallization from a mixture containing 4,4′-dihydroxydiphenylsulfone, 2,4′-dihydroxydiphenylsulfone, phenolsulfonic acid and phenol which is ... | 03/13/2007 |
| 7173155 | Terphenyl dihalide monomers having sulfonate groups and process for preparing the same The present invention relates to a terphenyl dihalide monomer having sulfonate groups and a process for preparing the same. More particularly, the present invention relates to a terphenyl dihalide monomer having sulfonate groups prepared by a process comprising obta... | 02/06/2007 |
| 7122294 | Photoacid generators with perfluorinated multifunctional anions Photoacid generators (PAGs) comprising photoactive moieties and perfluorinated, multifunctional anionic moieties (or incipient anionic moieties) are disclosed which provide photoacids with high acid strength, low volatility and low diffusivity. The present invention... | 10/17/2006 |
| 7109249 | Composition containing a cross-linkable matrix precursor and a poragen, and porous matrix prepared therefrom A suitable cross-linkable matrix precursor and a poragen can be treated to form a porous cross-linked matrix having a Tg of greater than 300° C. The porous matrix material has a lower dielectric constant than the corresponding non-porous matrix material,... | 09/19/2006 |
| 7053123 | Substituted (e)-styryl benzylsulfones for treating proliferative disorders (E)-Styryl benzylsulfones useful as antiproliferative agents, including, for example, anticancer agents, are provided according to formula I: wherein: R1 is selected from the group consisting of halogen, C1–C6 alkoxy, nitro, phosphonato, amino, sulfamyl... | 05/30/2006 |
| 7009055 | Preparation of Sulfonyl quinoline A dibromomethyl moiety is converted to a sulfonylmethyl moiety by treatment with a sulfinic acid salt. For example, (methyl-sulfonyl)methyl bromo-quinoline is prepared by the treatment of dibromomethyl bromo-quinoline with a sulfinic acid salt. ... | 03/07/2006 |
| 6998415 | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation. ... | 02/14/2006 |
| 6927309 | Sulfur compounds and intermolecular compounds containing the same as the component compounds The invention aims at providing novel sulfur compounds, molecular compounds containing the same as the component compound, and so on. The above aim is achieved by using sulfur compounds of the general formula (I) wherein Rs are each independently hydrogen, optionall... | 08/09/2005 |
| 6861562 | Process for producing mixture of dihydroxydiphenylsulfone isomers The present invention provides a process for producing a mixture of 4,4′- and 2,4′-dihydroxydiphenylsulfones comprising heating trihydroxytriphenyldisulfone or a mixture of dihydroxydiphenylsulfone isomers containing trihydroxytriphenyldisulfone in the presence ... | 03/01/2005 |
| 6833480 | (Z)-styrylbenzylsulfones and pharmaceutical uses thereof Substituted (Z)-styrylbenzyl sulfones of the formulae (I, II, III, IV), pharmaceutically acceptable salts thereof, and compositions thereof are provided as cell antiproliferative agents, including, for example, anticancer agents. ... | 12/21/2004 |
| 6762326 | C2-substituted idan-1-ones and their derivatives, processes for their preparation and their use as pharmaceuticals Embodiments of the invention relate to C2-substituted indan-1-ones and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention include compounds of formula I | 07/13/2004 |
| 6727386 | Aromatic imide and aromatic methylidynetrissulfonyl compounds and method of making A method is provided for making aromatic-imide and aromatic-methylidynetrissulfonyl species by reaction of aromatic species with a reactant according to formula (I): (X—SO2—)m—QH—(—SO2—R1)n ... | 04/27/2004 |
| 6723483 | Sulfonium salt compounds A triphenyl sulfonium salt compound shown by the general formula [1] or [3]. (wherein R1 and R2 are each independently a hydrogen atom or a lower alkyl group, provided that at least one of R1 | 04/20/2004 |
| 6692893 | Onium salts, photoacid generators, resist compositions, and patterning process Onium salts of arylsulfonyloxynaphthalenesulfonate anions with iodonium or sulfonium cations are novel. A chemically amplified resist composition comprising the onium salt as a photoacid generator is suited for microfabrication, especially by deep UV lith... | 02/17/2004 |
| 6686397 | Polysubstituted indan-1-ol systems for the prophylaxis or treatment of obesity Polysubstituted indan-1-ol compounds of formula I, its physiologically acceptable salts and physiologically functional derivatives are disclosed: ##STR1## Compositions comprising the same, methods of preparation and methods for the prophylaxis or treatmen... | 02/03/2004 |
| 6670401 | Polysubstituted indan-1-ol compounds, and methods for their preparation and use Polysubstituted indan-1-ol compounds, methods for their preparation; and methods for their use are disclosed herein. In particular, the invention relates to polysubstituted indan-1-ol compounds of the formula I ##STR1## and their physiologically acceptabl... | 12/30/2003 |
| 6667345 | Derivatives of C2-substituted indan-1-ol systems for the prophylaxis or treatment of obesity Derivatives of C2-substituted indan-1-ol compounds of the formula I: ##STR1## its physiologically acceptable salts, and its physiologically functional derivatives for the prophylaxis or treatment of obesity are disclosed herein. Compositions comprising th... | 12/23/2003 |
| 6657086 | C2-substituted indan-1-ols and their derivatives, processes for their preparation and their use as pharmaceuticals Embodiments of the invention relate to C2-substituted indan-1-ols and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of embodiments of the invention may include compounds of formula I ##STR1## in which... | 12/02/2003 |
| 6590126 | Industrial process for the production of diphenyl sulfone compounds A process for producing compounds of general formula (II) useful as the developer for leuco dyes to be used in thermosensible papers, which is excellent in productivity, economical efficiency and safety and permits the production of the compounds from con... | 07/08/2003 |
| 6582879 | Reactive photo acid-generating agent and heat-resistant photoresist composition with polyamide precursor The present invention relates to a reactive photo acid-generating agent and a heat-resistant photoresist composition comprising the same. In particularly, the present invention relates to the heat-resistant photoresist composition comprising the photo aci... | 06/24/2003 |
| 6548622 | Manufacture of polysulfones Polysulfones are manufactured by reacting a sulfuric acid or sulfur trioxide with a bireactive aromatic compound, using as a "promoter" a carboxylic acid anhydride. The product polymers are useful as molding resins.... | 04/15/2003 |
| 6482567 | Oxime sulfonate and N-oxyimidosulfonate photoacid generators and photoresists comprising same New photoacid generator compounds ("PAGs") are provided and photoresist compositions that comprise such compounds. In particular, non-ionic PAGs are provided that contain an oxime sulfonate group, and/or an N-oxyimidosulfonate group. PAGs of the invention... | 11/19/2002 |
| 6455738 | Process for the sulfonation of an aromatic compound A subject-matter of the present invention is a process for the sulfonation of an activated or deactivated aromatic compound. The invention applies to the preparation of aromatic sulfones. The process for the sulfonation of an aromatic compound according t... | 09/24/2002 |
| 6416928 | Onium salts, photoacid generators, resist compositions, and patterning process Onium salts of substituted phenylmethylbenzene-sulfonate anions with iodonium or sulfonium cations are novel. A chemically amplified resist composition comprising the onium salt as a photoacid generator is suited for microfabrication, especially by deep U... | 07/09/2002 |
| 6395724 | Multibinding inhibitors of cyclooxygenase-2 Disclosed are multibinding compounds which inhibit cyclooxygenase-2 (COX-2), an enzyme which catalyzes the first committed step in the biosynthesis of prostaglandins. The multibinding compounds of this invention containing from 2 to 10 ligands covalently ... | 05/28/2002 |
| 6380258 | Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds A sulfonyl divalent aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated sulfonyl divalent aromatic or heteroa... | 04/30/2002 |
| 6379590 | Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D ##STR1## wherein A' is se... | 04/30/2002 |
| 6359013 | Styryl sulfone anticancer agents Styryl sulfone compounds of the invention selectively inhibit proliferation of tumor cells, and induce apoptosis of such tumor cells, while sparing normal cells. The compounds, which are useful in the treatment of cancer, have the formula II: ##STR1#... | 03/19/2002 |
| 6358665 | Radiation-sensitive composition of chemical amplification type Disclosed is a chemically amplified radiation sensitive composition containing a hydroxystyrene resin and an onium salt precursor which generates a fluorinated alkanesulfonic acid as a photoacid generator, wherein the photoacid generator is a sulfonium or... | 03/19/2002 |
| 6355841 | Process for producing ଲ-carotene There are disclosed a process for producing a sulfon derivative of formula (1): ##STR1## wherein Ar represents an aryl group which may be substituted, R represents a lower alkyl group and the wavy line depicted by ##STR2## indicates a single bond and ste... | 03/12/2002 |
| 6348622 | Vitamin a related compounds and process for producing the same There is provided a compound of the formula[I]: ##STR1## wherein R represents a hydrogen atom or a protective group for a hydroxyl group; and A represents a hydrogen atom, a halogen atom or a group of the formula A1: ##STR2## Q represents Q3: ##STR3#... | 02/19/2002 |
| 6303630 | Diarylsulfone non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus In accordance with the present invention, there is now provided novel anti-HIV compounds of the formulae selected from the group consisting of: ##STR1## ##STR2## wherein R1 is hydrogen or C1 -C4 alkyl; R2 is hyd... | 10/16/2001 |
