The invention pertains to novel oligofunctional photoinitiators of the formula (1) or (1A). R1 and R2 are methyl or together are —(CH2)5—; and n is 2 or 3, and the solvent in (1A) is water or an organic solvent; and th...
|8586799||Compounds and methods for preparation of diarylpropanes|
Compounds of structure (I): including stereoisomers, tautomers and salts thereof, wherein R1, R2, R3, R4, R5, R6, X, Y and Z are as defined herein. Such comp...
|8324431||Process for preparing 2,4-dihydroxyphenyl 4-methoxybenzyl ketones|
The invention relates to a process for preparing 2,4-dihydroxyphenyl 4-methoxybenzyl ketones of the formula (I) by Friedel-Crafts acylation in hydrogen fluoride (HF). 2,4-Dihydroxyphenyl 4-methoxybenzyl ketones of the formula (I) in which
|8227643||Sirtuin 1 and the treatment of neurodegenerative diseases|
This invention relates to bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable salts and their use in the modulation of Sirtuin 1 (Sirt1) and there use in neuroprotection for subject suffering from neurodegenerative ...
The present invention relates to the use of compounds of the formula (I) where R stands for [lacuna] with radicals defined in the description, as antioxidants, to corresponding novel compounds and compositions, and to corresponding processes for the preparation of c...
There are disclosed compounds of formulae (I) or (II) in which A is selected from the group consisting of (1), (2), (3) and (4); OH, and one of R1 and R2 is selected from H, OH and OCH3, and the other of R1 and R2
|7714170||Use of compounds and compositions for the treatment of amyloid diseases|
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially Aβ amyloidosis, such as observed in Alzheimer'...
|7601876||Compounds, compositions and methods for the treatment of amyloid diseases such as systemic AA amyloidosis|
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially Aβ amyloidosis, such as obser...
|7598423||Potentiators of glutamate receptors|
This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application al...
|7446230||Dibenzoylmethane-based compounds, use as photoactivatable sunscreens and cosmetic compositions containing them|
The present invention relates to dibenzoylmethane-based compounds of formula 1, and also to salts or solvates thereof, and to the process for preparing them. T...
|7439407||Fluorinated pentacene derivative and method of producing same|
Fluorinated pentacene derivatives, for example, the novel compounds tetradecafluoropentacene, 5,6,7,12,13,14-hexafluoropentacene, 5,7,12,14-tetrafluoropentacene, and 6,13-difluoropentacene, and intermediates therefor are provided. And a method of producing fluorinat...
|7154007||Luminous compounds and labeling reagents using the same|
This invention provides: a compound represented by formula (I): R—Y—(—X-Phe-COCH2COCnF2n+1)m (I) wherein R denotes hydrogen, alkyl, phenyl, or a group capable of binding to a protein, peptid...
|7091385||Acylation using molecular sieve SSZ-71|
The present invention relates to new molecular sieve SSZ-71 prepared using a N-benzyl-1,4-diazabicyclo[2.2.2]octane cation as a structure-directing agent, methods for synthesizing SSZ-71 and processes employing SSZ-71 in a catalyst. ...
|7084304||Acylation using molecular sieve SSZ-70|
The present invention relates to new crystalline molecular sieve SSZ-70 prepared using a N,N′-diisopropyl imidazolium cation as a structure-directing agent, methods for synthesizing SSZ-70 and processes employing SSZ-70 in a catalyst. ...
|7049459||1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same|
This invention relates to 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone. This compound is convertible into 4-(4-methyl thio phenyl)-3-phenyl-2 (5H)-furanone by an economically viable process. This substituted furanone is an intermediate or starting compoun...
|7034166||Process for producing benzofuran derivative|
A novel process for efficiently and easily producing a compound represented by the formula: wherein ring A is a benzene ring that may be optionally further substituted in addition to the group represented by W, or a sal...
|6949680||Ketones as precursors of active compounds|
A compound of formula wherein Y represents a pyridyl group, or a phenyl group of formula wherein R3 represents a hydrogen atom, a CF3 group or an al...
The present invention provides a fragrance precursor of formula I: that is capable of forming a fragrant ketone of formula II: and a fragrant lactone of formula III:
|6930208||3-Keto- or 3- oxime-ether-substituted benzoylcyclohexanediones|
What is described are derivatives of benzoylcyclohexanediones of the formula (I) and their use as herbicides. In this formula (I), R1a, R1b, R1c, R2, R3, R4
A process for the production of coatings having scratch-resistant durable surfaces, in which there is used a photocurable formulation comprising a surface-active photoinitiator, concentrated at the surface of the formulation, of formula (Ia) or (Ib), wherein R and R...
|6906076||Compounds and methods of use to treat infectious diseases|
The present invention concerns alkyl aryl carbonyl compounds that possess anti-infective activity. The compounds of the invention can be used to target specific nuclear localization signal, thereby blocking importation of specific proteins or molecular complex into ...
|6844470||Process for the purification of 1,3-diketones|
A process for the purification of 1,3-diketones comprising reacting a 1,3-diketone with an earth metal or alkaline earth metal complexing agent in an organic solvent, isolating, washing and decomposing the resulting complex, and isolating the purified 1,3-diketone.
|6787672||Substituted chalcones as therapeutic compounds|
This invention pertains to substituted chalcones, specifically substituted 1-(4-methoxyphenyl)-3-(3,5-dimethoxyphenyl)prop-1-en-3-ones, which have therapeutic application, for example, as potent antiproliferative agents and antiinflammatory agents, and which have th...
|6768025||Benzoylcyclohexanedione derivatives and their use as herbicides|
Benzoylcyclohexanedione derivatives of the formula (I) and their use as herbicides are described. In this formula (I), R1, R3, and R4 are various radicals, L—(R2)n
|6730814||Clay based catalytic process for the preparation of acylated aromatic ethers|
This invention relates to a process for the preparation of acylated aromatic ethers, in particular the acylation of anisole (methoxybenzene) and veratrole (1,2-dimethoxybenzene) for the preparation of corresponding acylated aromatic ether, namely, p-methoxyacetophen...
|6699910||Ketone compounds and compositions for cholesterol management and related uses|
The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administ...
The present invention provides a method for enantioselectively reducing a prochiral carbon centered radical having one or more electron donator groups attached directly to the central prochiral carbon atom of the radical, and/or attached to a carbon atom ...
|6630606||Acylation reactions of aromatic substrates|
Method of performing alkylation or acylation reactions of aromatic substrates under supercritical or near-critical reaction conditions. In particular, a method of performing Friedel-Crafts alkylation or acylation reactions is disclosed under those conditi...
|6603046||Bis-aromatic a,ଲ-unsaturated ketones|
The invention is drawn to novel bis-aromatic a,ଲ-unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria....
|6579903||Klainetins and their derivatives, method for their preparation and use thereof|
The invention relates to compounds of formula I ##STR1## and of formula II ##STR2## in which R1, R2, R3, R4, R5, X1, X2, X3, X4, X5 and Y are def...
|6498195||Use of 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4'-hydroxyphenyl) as an anticarcinogenic agent|
Compositions and methods are provided for prevention and treatment of cancer. The compositions comprise pure hydroxylated chalcone compounds of licorice root (Glycyrrhiza glabra) including 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4'-hydroxyphenyl)...
The present invention is a fragrance precursor of formula I: ##STR1## for a fragrant ketone of formula II: ##STR2## and a fragrant ester of formula III: ##STR3## wherein, R1 to R5 represent independently H, --NO2, linear o...
|6459000||Process for the liquid phase acylation of aromatic compounds|
The present invention provides a liquid phase process for the acylation of aromatic compound by an acylating agent of the formula (R5 R6 R7)--Y--Z to obtain the corresponding acylated compound using a solid catalyst compri...
|6423740||Chalcones having antiproliferative activity|
The invention relates to a novel class of compounds that have structures related to certain naturally occurring or synthetic chalcones. The invention also relates to pharmaceutical compositions comprising the compounds and methods for treating certain dis...
|6417357||Coupling reactions with palladium catalysts|
This invention relates to a novel, inventive process for the preparation of biphenyls or aromatic olefins by coupling reactions of the Suzuki coupling and Heck coupling type, using allylpalladium catalysts of the μ-halo(triisopropylphosphine)(η3
|6399835||Process for electrophilic aromatic substitution|
Processes for the electrophilic substitution of aromatic compounds, such as alkylation, with a desired substituent are disclosed. The processes include contacting the aromatic compound, a precursor of the desired substituent and an aqueous reagent contain...
The invention relates to 2-(3-alkenylbenzoyl)cyclohexane-1,3-diones of the formula I ##STR1## where the variables have the following meanings: R1, R2 are hydrogen, nitro, halogen, cyano, thiocyanato, alkyl, haloalkyl, alkoxyalkyl, al...
|6350875||Synthesis of cyclooctatetraene derivatives and their use as electron transporters in organic light emitting diodes|
The synthesis of asymmetric tetrasubstituted cyclooctatetraenes ("COTs") and the use of said compounds in organic light emitting diodes is reported, wherein said COTs represent a class of wide gap electron transporters that are readily deposited in vacuum...
|6346260||Microbicidal active ingredients|
The use of hydroxyphenyl-1,3-propanediones of formula: ##STR1## wherein R1 and R2 are each independently of the other hydrogen, C1 -C12 alkyl, C1 -C12 alkoxy, trifluoro-C1 -C3
|6284915||Process for preparing 2-amino malonic acid derivatives and 2-amino-1,3-propanediol derivatives, and intermediates for preparing the same|
A process for preparing 2-amino malonic acid derivatives of formula (1): ##STR1## wherein A is linear or branched chain alkylene having from 1 to 10 carbon atoms, R1 is linear or branched chain alkyl having from 2 to 20 carbon atoms, R2