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| Number | Title | Issue Date |
| 7468462 | Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders The present invention is directed to novel compounds according to formulae wherein R1, R2, R3 and R4 are as defined herein. The invention also discloses methods of preparation, ph... | 12/23/2008 |
| 7326815 | Selective oxidation of alkylbenzenes The present invention relates to a process for producing phenol and a ketone of general formula R1COCH2R3 (I), in which R1 and R2 each independently represent an alkyl group having from 1 to 4 carbon atoms, said... | 02/05/2008 |
| 7235698 | Enantioselective, catalytic allylation of ketones and olefins Compounds containing a substituted or unsubstituted allyl group directly bound to a chiral carbon atom are prepared enantioselectively. Starting reactants are either chiral or achiral, and may or may not contain an attached allyloxycarbonyl group as a substituent. C... | 06/26/2007 |
| 7202196 | Selective herbicide comprising a tetrazolinone derivative The invention relates to novel herbicidal synergistic active compound combinations comprising a known tetrazolinone derivative and known herbicidally active compounds and/or safeners, which compositions can be used with particularly good results for the selective co... | 04/10/2007 |
| 7176315 | Enantiomers of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1H-quinolin-2-one and salts thereof, useful in the treatment of cancer This invention relates to the enantiomers of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1H-quinolin-2-one, prodrugs thereof, and pharmaceutically acceptable salts and solvates of said compou... | 02/13/2007 |
| 7166749 | Process for preparing chiral aromatic α-hydroxy ketones using 2-hydroxy-3-oxoacid synthase A biotransformation process for preparing chiral aromatic-hydroxy ketones in high yields is described, using 2-hydroxy-3-oxoacid synthase, such as AHAS or TSAS. Optionally substituted arylaldehydes and -oxoacids react in this process to provide pure enantiomers, use... | 01/23/2007 |
| 7145041 | Method for producing saturated alcohols, ketones, aldehydes and carboxylic acids The invention relates to a method for catalytically oxidizing unsaturated hydrocarbons to form oxidation products, and to the production of saturated alcohols, ketones, aldehydes or carboxylic acids by subsequently hydrogenating the oxidation product. A compound of ... | 12/05/2006 |
| 7115762 | Polystyrene-supported palladacycle catalysts This invention relates to a recyclable palladacycle catalyst of formula in which each is a single bond or a double bond, provided that if one is a double bond, its neighboring ... | 10/03/2006 |
| 7094919 | Preparation of substituted aromatic carboxylic acid esters Methods for preparing substituted aromatic carboxylic acid esters are described. In particular, the invention relates a method for preparing a nitro-substituted aromatic carboxylic acid ester: Additionally the inventio... | 08/22/2006 |
| 7087791 | Catalysed acylation of alkylated benzene derivatives An ecofriendly process for acylation of an alkylated benzene derivative has increased selectively towards para position and comprises a step of reacting the alkylated benzene derivative with an acylating agent in the presence of nitrobenzene, dichlorobenze, dimethyl... | 08/08/2006 |
| 7084306 | Process for preparing β-diketone compound and process for preparing metal complex thereof Disclosed is a process for preparing 2,2,6,6-tetramethyl-3,5-heptanedione, comprising reacting a pivalic acid alkyl ester with pinacolone in the presence of an alkali metal alkoxide catalyst using a pivalic acid alkyl ester as a solvent but using no other solvent or... | 08/01/2006 |
| 7019175 | Catalytic oxidation process The invention provides a process for the catalytic oxidation of an alkane, which comprises contacting the alkane with a source of oxygen in the presence of a catalyst comprising a compound of the formula (2) where R1 and R2 independently repres... | 03/28/2006 |
| 6930207 | Trifluoroacetylalkyl-substituted phenyl, phenol and benzoyl compounds and related methods of treatment Novel and known trifluoroacetyl-substituted phenyl, phenol and benzoyl compounds for the treatment and/or inhibition of obesity and of concomitant and/or secondary diseases involved therewith, in particular metabolic syndrome and cardiovascular diseases. Novel trifl... | 08/16/2005 |
| 6924397 | Process for the preparation of α-chloroketones from alkyl esters The present invention relates to a process for the preparation of α-chloroketones from readily available alkyl esters by the reaction of a sulfoxonium ylide on said alkyl esters to generate a keto sulfoxonium ylide that is in turn treated with anhydrous HCl. ... | 08/02/2005 |
| 6919485 | Benzophenones, the production thereof and their use for controlling plant pathogenic fungi The invention relates to benzophenones of formula (I), in which the substituents have the following meanings: X represents halogen; R1 represents hydrogen, halogen, C1-C6 alkyl, halo-C1-C2 alkyl, C1-C... | 07/19/2005 |
| 6881865 | Method for preparing cyclohexyl phenyl ketone from 1,3-butadiene and acrylic acid Disclosed is a synthesis method of cyclohexyl phenyl ketone with a high selectivity and a high yield from 1,3-butadiene and acrylic acid in the presence or absence of benzene or a non-aromatic organic solvent in the same reaction without a step of separating or puri... | 04/19/2005 |
| 6872854 | Complexes of metal salts of organic acids and beta-diketones and methods for producing same Metal salts of organic acids complexed with β-diketone compounds are multifunctional complexes useful in the formulation of stabilizers for halogenated resins. These complexes may be used jointly with other low toxicity intermediates, such as zinc or magnesium inte... | 03/29/2005 |
| 6864394 | Method for producing ketones from carboxylic acid anhydrides The invention relates to a method for producing ketones by reacting boric acid derivates with carbocylic acid anhydrides in the presence of a transition metal catalyst. The carboxylic acid anhydrides can either be used in isolated form or produced from carboxylic ac... | 03/08/2005 |
| 6852893 | Method for oxidizing hydrocarbons The invention relates to a method for oxidizing substrates such as hydrocarbons, waxes or soot. The method involves the use of a compound of formula (I) in which: R1 and R2 represent H, an aliphatic or aromatic alkoxy radical, carboxyl radical, alkoxycarbonyl radica... | 02/08/2005 |
| 6787671 | Catalytic osmium-assisted oxidative cleavage of olefins An osmium-assisted process for the oxidative cleavage of oxidizable organic compounds such as unsaturated organic compounds, including alkenes and olefins into aldehydes, carboxylic acids, esters, or ketones. The process uses a metal catalyst comprising osmium and a... | 09/07/2004 |
| 6683220 | Process for the preparation of optically pure or enriched racemic tetralone A process for producing substantially optically pure sertraline utilizes chromatographic separation on a solid stationary chiral phase of spherical clay particles having an interlayer containing an optically pure metal-organic complex, and a liquid mobile... | 01/27/2004 |
| 6642418 | Processes for preparing intermediates The invention relates to processes for the preparation of compounds of formula (I), wherein R1 and R2 are as defined in the description. ##STR1##... | 11/04/2003 |
| 6639112 | Method for preparing ketones by pyrogenic reaction of aldehydes, alcohols, acids or esters The invention concerns a method for preparing ketones of formula (I) wherein A and B are as defined in claim 1, consisting of reacting at a temperature ranging between 250 and 500° C. a compound of formula (II): A--X with a compound of formula (III): B--... | 10/28/2003 |
| 6617473 | Production of dibenzosuberenone derivatives by catalytic dehydrogenation The invention relates to a preparation process for derivatives by catalytic dehydrogenation of dibenzosuberone derivatives.... | 09/09/2003 |
| 6608217 | Process for producing 4-substituted benzopyran derivatives The present invention relates to a first process for producing a 2,2-bis(fluoromethyl)-6-(perfluoroalkyl)-2H-1-benzopyran-4-carboxylic acid. The first process includes the steps of (a) reacting a 2,2-bis(fluoromethyl)-6-(perfluoroalkyl)-2H-1-benzopyran-4-... | 08/19/2003 |
| 6593499 | Process for the preparation of phenyl ketones The present invention relates to a process for the preparation of phenyl ketones of formula-I, ##STR1## Wherein R represents --COCH3, --COC2 H5 or --COC6 H5, which comprises acylating the biphenyl wit... | 07/15/2003 |
| 6506942 | Process for the preparation of carbonyl compounds by cleavage of hydroxycarboxylic acids The invention relates to a process for the preparation of a carbonyl compound of the general formula (1) R1 R2 C.dbd.O (1), in which a ଲ-hydroxycarboxylic acid or its salt of the general formula (2) R1 R2 C(OH... | 01/14/2003 |
| 6492539 | Preparation of preparing substituted indanones a process for the preparation of indanones of the formula II from, indanones of the formula I or of indanones of the formula IIa from indanones of the formula Ia ##STR1## comprises reacting an indanone of the formula I or Ia with a coupling component... | 12/10/2002 |
| 6486356 | Process for the preparation of 1-aryl-3-cyclopropyl-1,3-propanediones A process for preparing a compound of the formula: ##STR1## which comprises reacting a compound of the formula: ##STR2## wherein R1 is C1-6 straight- or branched-chain alkyl, with a compound of the formula: ##STR3## in an aproti... | 11/26/2002 |
| 6444854 | Process for the production of enantiomerically pure or optically enriched sertraline-tetralone using continuous chromatography A process for the production of enantiomerically pure or optically enriched sertraline-tetralone from a mixture containing two enantiomers using continuous chuomatography. The chromatography comprises a liquid mobile phase comprising at least one polar so... | 09/03/2002 |
| 6441244 | Benzophenones and the use thereof as photoinitiators The invention relates to new compounds of the formula (I) ##STR1## in which R is phenyl, C1-4 alkyl-, C1-4 alkoxy- or halogen-substituted phenyl, naphthyl or an aromatic ring containing heteroatoms; X is O or S; R1 and R2 | 08/27/2002 |
| 6429339 | Method for producing cyclopentanone A process for preparing cyclopentanone by reacting adipic esters of the formula R1 OOC--(CH2)4 --COOR2 I where R1 and R2 are each alkyl having from 1 to 12 carbon atoms, cycloalkyl having 5 or ... | 08/06/2002 |
| 6417405 | Synthesis of cyclopentadiene or substituted cyclopentadiene compounds Substituted or unsubstituted cyclopentadienyl are prepared by reducing 4-ketocyclopentene to an alcohol, replacing the hydroxyl functionality with a leaving group and deprotonating the resulting product under base induced elimination conditions.... | 07/09/2002 |
| 6410795 | Process for base-promoted condensation reactions and base reagent therefor A method for the preparation of 1,3-diketones is disclosed wherein the method comprises the steps of: (A) mixing an alkali metal base with a hindered alcohol in an aromatic hydrocarbon solvent; (B) boiling the mixture and azeotropically distilling water formed... | 06/25/2002 |
| 6372693 | Substituted 2-(3-alkenyl-benzoyl)-cyclohexane-1,3-diones The invention relates to 2-(3-alkenylbenzoyl)cyclohexane-1,3-diones of the formula I ##STR1## where the variables have the following meanings: R1, R2 are hydrogen, nitro, halogen, cyano, thiocyanato, alkyl, haloalkyl, alkoxyalkyl, al... | 04/16/2002 |
| 6353139 | Method for preparing ketones A method for preparing ketones has advantages of improving yields and reducing the time of the reactions due to high efficiency of catalysts. Ketones are prepared by reacting an aliphatic or an aromatic aldehyde with a vinyl olefin having an aliphatic or ... | 03/05/2002 |
| 6310256 | Synthesis of 4-ketocyclopentene compounds A process for forming 4-ketocyclopentene and substituted 4-ketocyclopentene compounds starting from the corresponding 1-carbohydrocarbyloxy-2-keto-4-hydroxy-5-cyclopentene by reduction followed by decarboxylation.... | 10/30/2001 |
| 6159988 | Arylcycloalkyl derivatives, their production and their use Compounds of formula I, ##STR1## and the physiologically tolerable salts thereof, wherein the substituents R1 -R4 have the meanings given in the specifications and show an activity against inflammatory conditions.... | 12/12/2000 |
| 6143935 | Process for the preparation of 1,3-dicarbonyl compounds The condensation reaction of a ketone with either an ester or a carbonate to form, respectively, a 1,3-diketone or a ଲ-ketoester often affords poor results under the standard condensation reaction conditions. High yields and high purities of the des... | 11/07/2000 |
| 6011178 | Process for the preparation of 2-amino-4,5,3',4'-tetramethoxybenzophenone 2-Amino-4,5,3',4'-tetramethoxybenzophenone of the formula: ##STR1## is prepared by mononitration of 3,3',4,4'-tetramethyoxybenzophenone using nitric acid in the presence of acetic acid, and subsequent reduction of the nitro group. The compound is an ... | 01/04/2000 |
