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| Number | Title | Issue Date |
| 8101804 | Process for the synthesis of (E)-stilbene derivatives which makes it possible to obtain resveratrol and piceatannol A subject-matter of the present invention is a novel process for the synthesis of (E)-stilbene derivatives targeted at obtaining in particular resveratrol and piceatannol. ... | 01/24/2012 |
| 7595425 | Friedel-crafts acylation process in ionic liquids A preparation process of aromatic ketones by a Friedel-Crafts acylation reaction in an ionic liquid of formula (I), in the absence of any other catalyst and/or solvent. In formula (I), [Q]+ is selected from substituted-imidazolium cations, substituted-pyr... | 09/29/2009 |
| 7572938 | Precursors for ketones and aldehydes The present invention refers to compounds of formula I as precursors for a ketone of formula II, an aldehyde or ketone of formula III, and an aldehyde or ketone of formula IV, | 08/11/2009 |
| 7439407 | Fluorinated pentacene derivative and method of producing same Fluorinated pentacene derivatives, for example, the novel compounds tetradecafluoropentacene, 5,6,7,12,13,14-hexafluoropentacene, 5,7,12,14-tetrafluoropentacene, and 6,13-difluoropentacene, and intermediates therefor are provided. And a method of producing fluorinat... | 10/21/2008 |
| 7368608 | 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivatives and a process for preparing 2-amidomethyl-1,4-benzodioxane derivatives An 1-amido-3-(2-hydroxyphenoxy)-2-propanol derivative represented by the following formula (1), wherein cycle A may have further 1 to 4 substituents, and said substituent means a substituent selected from the group consisti... | 05/06/2008 |
| 7355063 | Shogaol compound and tyrosinase activity inhibitor comprising the compound The compound represented by the following formula (1): wherein A, B, R1, R2, R3 and Z are as defined in the specification is analogous to shogaol and gingerol useful in the fields of foods, medicines, quasi-drugs, cosmetics... | 04/08/2008 |
| 7329782 | Compounds for the treatment of metabolic disorders Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed. ... | 02/12/2008 |
| 7285678 | Purification of 2-nitro-4-methylsulphonylbenzoic acid A method for removing impurities from 2-nitro-4-methylsulfonylbenzoic acid which comprises at least two of the following steps, in any order, (a) dissolving 2-nitro-4-methylsulfonylbenzoic acid in water at a pH of about 2 to 10, followed by filtration; (b) contactin... | 10/23/2007 |
| 7273954 | Catalytic method for the production of carbonyl compounds The invention relates to a catalytic method for the production of aliphatic and aromatic carbonyl compounds with at least one aldehyde or ketone function, whereby said compounds can also comprise at least one aldehyde and ketone function. A starting material compris... | 09/25/2007 |
| 7241755 | Epothilone derivatives The present invention relates to compounds of the formula in which the variables G, W, Q, X, Y, B1, B2, Z1, Z2, and R1–R7 are as defined herein,... | 07/10/2007 |
| 7208623 | Process for the manufacture of HMG-CoA reductase inhibitory mevalonic acid derivatives The invention relates to a process for the manufacture of a compound of formula: (Formula I); or a salt, especially a pharmaceutically acceptable salt with a base, thereof or a lactone thereof wherein the element (a) represents —CH2—CH2— ... | 04/24/2007 |
| 7125899 | Epothilone derivatives The present invention relates to epothilone derivatives, having the following formula: in which the variables G, W, Q, X, Y, B1, B2, Z1, Z2, and R1–R7... | 10/24/2006 |
| 7091385 | Acylation using molecular sieve SSZ-71 The present invention relates to new molecular sieve SSZ-71 prepared using a N-benzyl-1,4-diazabicyclo[2.2.2]octane cation as a structure-directing agent, methods for synthesizing SSZ-71 and processes employing SSZ-71 in a catalyst. ... | 08/15/2006 |
| 7084304 | Acylation using molecular sieve SSZ-70 The present invention relates to new crystalline molecular sieve SSZ-70 prepared using a N,N′-diisopropyl imidazolium cation as a structure-directing agent, methods for synthesizing SSZ-70 and processes employing SSZ-70 in a catalyst. ... | 08/01/2006 |
| 7067158 | Preparation for the relief of disease A composition including (a) a Platelet Activating Factor (PAF) Inhibitor and (b) an antioxidant which interferes with the arachidonic acid cascade and also has antioxidant activity. The composition is useful for the treatment or the relief of inflammatory diseases, ... | 06/27/2006 |
| 7034165 | Protected 3,-5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production The invention relates to 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and epothilone derivatives and process for the production of these new intermediate products in the synthesis and the use for the production of epothilones or epothil... | 04/25/2006 |
| 7012071 | Compounds for the treatment of metabolic disorders Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed. ... | 03/14/2006 |
| 6972335 | Synthesis of epothilones, intermediates thereto, analogues and uses thereof The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention furth... | 12/06/2005 |
| 6965034 | Synthesis of epothilones, intermediates thereto and analogues thereof The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates ... | 11/15/2005 |
| 6946491 | Compounds for the treatment of metabolic disorders Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed. ... | 09/20/2005 |
| 6921841 | Process for the synthesis of optically active anthracyclines It is described a process for the synthesis of optically active anthracyclines by the fact that the key intermediate (R)2-acetyl-2-hydroxy-1,2,3,4-tetrahydronaphtalene 5,8-dialkoxy-3,4-dihydronaphtalene by acylation asymmetric dihydroxylation, transformation into ch... | 07/26/2005 |
| 6849768 | Sol-gel derived porous microcomposite of perfluorinated ion-exchange polymer and metal oxide Porous microcomposites have been prepared from perfluorinated ion-exchange polymer and metal oxides such as silica using the sol-gel process. Such microcomposites possess high surface area and exhibit extremely high catalytic activity. ... | 02/01/2005 |
| 6646166 | Processes for the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro 2 butene compounds The present invention provides an improved process for the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene compounds of the structural formula I ##STR1## In addition, the present invention provides an improved process for the preparation of 1,4-diaryl-2-... | 11/11/2003 |
| 6630606 | Acylation reactions of aromatic substrates Method of performing alkylation or acylation reactions of aromatic substrates under supercritical or near-critical reaction conditions. In particular, a method of performing Friedel-Crafts alkylation or acylation reactions is disclosed under those conditi... | 10/07/2003 |
| 6623665 | Second-order nonlinear optics material, the devices using same and methods of preparing The present invention relates to nonlinear optical (NLO) materials, compositions thereof and NLO devices using polymeric matrices supporting a second order NLO material defined by the formula where ED is an electron donating moiety, B is a bridging moiety, and... | 09/23/2003 |
| 6603015 | Synthesis of epothilones Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment A and C precursors. Segment C precursors are prepared ... | 08/05/2003 |
| 6586598 | , -dibromo--chloro-acetophenones as synthons This disclosure relates to the use of ,-dibromo--chloroacetophenone compounds as intermediates for the preparation of aromatic carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2-trifluoroethoxy)-,&#... | 07/01/2003 |
| 6525226 | Process for preparation of substituted aromatic compound employing friedel-crafts reaction using a reusable basic anionic clay catalyst A process for Friedel-Crafts type liquid-phase alkylation or acylation of an aromatic compound using a hydrotalcite-type basic anionic clay catalyst represented by a formula: [(M2+)1-x (M3+)x (OH)2 ]x... | 02/25/2003 |
| 6518316 | Cytokine production and tyrosine kinase inhibitors A compound of formula (I), wherein X is .dbd.O, .dbd.N--OR6, ଲNHR or ଲOH wherein R6 is H or C1 -C6 alkyl, bond a is oriented γ or δ and R is H, C1 -C6 alkyl which is un... | 02/11/2003 |
| 6486356 | Process for the preparation of 1-aryl-3-cyclopropyl-1,3-propanediones A process for preparing a compound of the formula: ##STR1## which comprises reacting a compound of the formula: ##STR2## wherein R1 is C1-6 straight- or branched-chain alkyl, with a compound of the formula: ##STR3## in an aproti... | 11/26/2002 |
| 6476266 | Diamino compound and production process for the same Provided is a diamino compound suitable for obtaining a polyimide which can form a liquid crystal alignment film capable of providing a liquid crystal display element, an intermediate therefor and a production process for the same. The above production pr... | 11/05/2002 |
| 6437191 | Process for the acylation of aromatic compounds using a reusable solid catalyst comprising indium halide A process for the liquid phase acylation of aromatic compounds by acyl halides to corresponding acylated aromatic compounds, using a reusable solid catalyst comprising indium halide represented by a formula: Mx In1-x Ay(a)/s wherein, S is... | 08/20/2002 |
| 6433227 | USE OF TRIS (TRIFLUORO METHYLSULFONYL) METHANE, IN ADDITION TO ALKALINE METAL SALTS AND ALKALINE-EARTH METAL SALTS THEREOF AS CATALYSTS DURING C-C BONDING SYNTHESES AND THE NOVEL MG SALT OF TRIS (TRIFLUORO METHYLSULFONYL) METHANE Compounds are used as catalysts according to general formula (1) M+x (C(SO2 CF3)3)x, whereby x is equal to 1 or 2; M represents one hydrogen or alkaline metal atom when x equals 1; and M represents on... | 08/13/2002 |
| 6410794 | Process for preparation of pharmaceutically desired chiral tetralone from tetralones Improved processes for preparation of tetralones in high enantiomeric purity centers on resolution using simulated moving bed chromatography of a racemic tetralone derivative. Resolution is effected with high enantiomeric purity, and subsequent reactions ... | 06/25/2002 |
| 6403835 | Acylation of an organic group over a zeolite The invention relates to the shape selective acylation of an organic compound. In particular, the invention describes a process for such acylation wherein the process comprises reducing the number of surface acid sites without dealuminations on at least a... | 06/11/2002 |
| 6384251 | Process for effecting allylic oxidation using dicarboxylic acid imides and chromium reagents A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of an N-hydroxy dicarboxylic acid imide and a chromium-containing oxidant. The reaction can co... | 05/07/2002 |
| 6380436 | Process for the synthesis of alkoxyalkyl (trifluormethylphenyl) methanones A new process is described for the preparation of (alkoxyalkyl)(4-trifluoromethylphenyl)methanones. The process comprises reacting a 4-trifluoromethylbenzonitrile with an alkoxyalkyl Grignard in the presence of a suitable polar aprotic solvent. The compou... | 04/30/2002 |
| 6362375 | Process for the preparation of aryl ketones generating reduced amounts of toxic byproducts An efficient, cost-effective method useful for the production of aryl ketones that minimizes the generation of toxic byproducts is disclosed. The method utilizes a metal triflate salt to catalyze the reaction between the carboxylic acid substrate and the ... | 03/26/2002 |
| 6355815 | Method of producing hydrogen peroxide and reaction promoters therefor A cyclic anthraquinone process for producing hydrogen peroxide using at least two differently substituted 2-alkylanthraquinones and/or their tetrahydro derivatives. The working solution to be used contains (i) at least one reaction carrier from the series... | 03/12/2002 |
| 6313351 | Process for producing alicyclic monoketones and process for producing alicyclic diketones The process for producing alicyclic monoketones (hydroxyphenylcyclohexanone derivatives) according to the present invention comprises hydrogenating substituted bisphenols such as bisphenol A in a solvent in the presence of a palladium/alkali metal catalys... | 11/06/2001 |
