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| Number | Title | Issue Date |
| 7935848 | Butone derivatives useful as cooling agents Cooling compounds of formula (I) wherein R1 is selected from the group consisting of hydrogen, methyl, C1-C3 alkoxy, phenyl, C1-C3 alkylphenyl, C1-C3 | 05/03/2011 |
| 7582801 | Synthesis of [1-C]pyruvic acid], [2-C]pyruvic acid], [3-C]pyruvic acid] and combinations thereof The present invention is directed to labeled compounds, of the formulae wherein C* is each independently selected from the group consisting of 13C and 12C with the proviso that at least one C* is ... | 09/01/2009 |
| 7501544 | Process for the production of cyclic diketones The present invention relates to a process for the preparation of compounds of formula (I), wherein the substituents are as defined in claim 1, by reacting a compound of formula (II), either with a chlorination or bromination agent or with a compound of formu... | 03/10/2009 |
| 7432284 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 10/07/2008 |
| 7357964 | Liquid-crystalline vinyl ketone derivatives and their polymers Provided is a liquid-crystalline, polymerizable vinyl ketone compound of formula (1): Preferably, R1 is hydrogen, halogen, —CN, —CF3, —CF2H, —CFH2, —OCF3, —... | 04/15/2008 |
| 7304028 | Use of methyl benzoic acid ester in perfume compositions The use of 2-methyl-benzoic acid methyl ester as a fragrance chemical, suitable for use in creating fragrance, and scents in items such as perfumes, colognes and personal care products is disclosed. ... | 12/04/2007 |
| 7291654 | Storage stability of photoinitiators Compounds of formula (I), wherein R1 is hydrogen or alkyl; R2 is C1-C4alkoxy or a morpholino radical; and R3 is hydrogen or C1-C4alkoxy, are suitable for improving the solubility of specifi... | 11/06/2007 |
| 7268242 | Chelating carbene ligand precursors and their use in the synthesis of metathesis catalysts Chelating ligand precursors for the preparation of olefin metathesis catalysts are disclosed. The resulting catalysts are air stable monomeric species capable of promoting various metathesis reactions efficiently, which can be recovered from the reaction mixture and... | 09/11/2007 |
| 7214831 | Histone deacetylase inhibitors based on alpha-chalcogenmethylcarbonyl compounds Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, for example, an alpha-chalcogenmethylcarbonyl group, such as an alpha-ketothio group, can inhibit histone deacetylase. Histone deacetylase inhibition can re... | 05/08/2007 |
| 7211603 | Enediyne compounds and methods related thereto The invention provides novel tetradentate enediyne ligands that are themselves thermally stable, yet react at about room temperature or slightly higher upon addition of metal ions or under photothermal conditions. In another aspect of the invention, a method of trea... | 05/01/2007 |
| 7176177 | Aromas and aroma compositions containing 4,8-dimethyl-3,7-nonadien-2-one, and a method for the production thereof 4,8-dimethyl-3,7-nonadien-2-one has aromatizing properties and increases the extendibility and intensity of the aroma when used in an aroma composition. ... | 02/13/2007 |
| 7078431 | 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders It has been discovered certain 1,3-bis-(substituted-phenyl)-2-propen-1-ones, including compounds of formula (I) inhibit the expression of VCAM-1, and thus can be used to treat a patient with a disorder mediated by VCAM-1. Examples of inflammatory disorders that are ... | 07/18/2006 |
| 7049459 | 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same This invention relates to 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone. This compound is convertible into 4-(4-methyl thio phenyl)-3-phenyl-2 (5H)-furanone by an economically viable process. This substituted furanone is an intermediate or starting compoun... | 05/23/2006 |
| 7034187 | Poly(aralkyl ketone)s and methods of preparing the same Disclosed are processes for preparing modifiable poly(aralkyl ketone)s having active methylene group(s) in the main chain comprising reacting an aralkanoic acid or mixtures thereof in the presence of one alkane or aryl sulfonic acid and a condensing agent. Also disc... | 04/25/2006 |
| 7022664 | 1,2 Substituted 2,3-dihydro-1H-5,9 dioxacyclohepta[F]indden-7-ones and 7-substituted benzo[B][1,4]dioxepin-3-ones The invention relates to 1,2-substituted 2,3-dihydro-1H-5,9-dioxacyclohepta[f]inden-7-ones and 7-substituted benzo[b][1,4]dioxepin-3-ones and to the use of these compounds in fragrance compositions. ... | 04/04/2006 |
| 6956061 | Polyisoprenylbenzophenone derivatives, processes for their preparation and use thereof The present invention relates to compounds of the formula (I): which are produced by the plant Garcinia punctata, chemical derivatives derived therefrom, a process for their preparation, and their use as pharmac... | 10/18/2005 |
| 6939845 | Fragrance precursors The present invention provides a fragrance precursor of formula I: that is capable of forming a fragrant ketone of formula II: and a fragrant lactone of formula III: | 09/06/2005 |
| 6939479 | Cycloalkanone derivatives Described herein are compounds of formula I wherein M1, M2 and M3 have the meanings recited in the disclosure, liquid crystalline mixtures and polymers containing them, and the use of t... | 09/06/2005 |
| 6921841 | Process for the synthesis of optically active anthracyclines It is described a process for the synthesis of optically active anthracyclines by the fact that the key intermediate (R)2-acetyl-2-hydroxy-1,2,3,4-tetrahydronaphtalene 5,8-dialkoxy-3,4-dihydronaphtalene by acylation asymmetric dihydroxylation, transformation into ch... | 07/26/2005 |
| 6906076 | Compounds and methods of use to treat infectious diseases The present invention concerns alkyl aryl carbonyl compounds that possess anti-infective activity. The compounds of the invention can be used to target specific nuclear localization signal, thereby blocking importation of specific proteins or molecular complex into ... | 06/14/2005 |
| 6888033 | Anti-viral compounds A compound having the formula (I) wherein the substituents are defined herein. Also provided are pharmaceutical compositions including a compound of formula (I) in a pharmaceutical carrier, for treating a disease caused ... | 05/03/2005 |
| 6706927 | Alkyne ketones Provided are processes for the preparation of the compound of the formula wherein R1, R3 and R4 are independently selected from the group consisting of hydrogen, halogen, hydroxyl, nitro,... | 03/16/2004 |
| 6669994 | Water-soluble coating agents bearing initiator groups A method of forming a polymer layer on a support surface by the use of a coating agent and polymerizable compounds. The coating agent provides photoreactive groups adapted to attach the agent to the surface, as well as photoreactive groups adapted to rema... | 12/30/2003 |
| 6623665 | Second-order nonlinear optics material, the devices using same and methods of preparing The present invention relates to nonlinear optical (NLO) materials, compositions thereof and NLO devices using polymeric matrices supporting a second order NLO material defined by the formula where ED is an electron donating moiety, B is a bridging moiety, and... | 09/23/2003 |
| 6603015 | Synthesis of epothilones Commercially feasible methods for synthesizing various epothilones precursors needed for the preparation of final epothilones are provided, including techniques for the synthesis of epothilone segment A and C precursors. Segment C precursors are prepared ... | 08/05/2003 |
| 6586598 | , -dibromo--chloro-acetophenones as synthons This disclosure relates to the use of ,-dibromo--chloroacetophenone compounds as intermediates for the preparation of aromatic carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2-trifluoroethoxy)-,&#... | 07/01/2003 |
| 6541672 | Derivatives of benzilidine cyclohexanone, benzilidine cyclopentanone, and benzilidine acetone and their synthesis The invention deals with the derivatives of benzilidine having basic formula as follows (I): ##STR1## wherein X can be cyclohexanone, cyclopentanone, or acetone, while Y and Z can be either electron withdrawing, electron donating or steric group. Y m... | 04/01/2003 |
| 6504036 | 2- and 2.5-substituted phenylketoenols The invention relates to novel phenyl-substituted cyclic ketoenols of the formula (I) ##STR1## in which Het represents one of the groups ##STR2## in which A, B, D, G, X and Z are each as defined in the description, to a plurality of processes and intermed... | 01/07/2003 |
| 6457303 | Synthesis of epothilones Various epothilone precursors needed for the preparation of final epothilones are provided.... | 10/01/2002 |
| 6433210 | Process for producing substituted arylpyrazoles The invention relates to a process for preparing substituted arylpyrazoles of the general formula (I) ##STR1## in which R1, R2, R3 and R4 are each as defined in the description, and to novel intermediates for pr... | 08/13/2002 |
| 6414179 | Alpha-and beta-substituted trifluoromethyl ketones as phospholipase inhibitors Inhibitors of the cytosolic phospholipase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula ##STR1## where X, Z, R1, R2, ... | 07/02/2002 |
| 6407137 | Dopamine analog amide The invention involves the formation of a prodrug from a fatty acid carrier and a neuroactive drug. The prodrug is stable in the environment of both the stomach and the bloodstream and may be delivered by ingestion. The prodrug passes readily through the ... | 06/18/2002 |
| 6399785 | Multiply-substituted fullerenes The invention is directed to multiply-substituted fullerene derivatives of novel configurations, and methods for their preparation and use. The methods involve the combinatorial synthesis of a library of fullerene derivatives and comprises the steps of fo... | 06/04/2002 |
| 6355815 | Method of producing hydrogen peroxide and reaction promoters therefor A cyclic anthraquinone process for producing hydrogen peroxide using at least two differently substituted 2-alkylanthraquinones and/or their tetrahydro derivatives. The working solution to be used contains (i) at least one reaction carrier from the series... | 03/12/2002 |
| 6340761 | Intermediates useful for the preparation of antihistaminic piperidine derivatives The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula ##STR1## wherein W represents --C(.dbd.O)-- or --CH(OH)--; R1 represents... | 01/22/2002 |
| 6326520 | Optically active compound and method for producing same The invention relates to a method for producing a novel optically active compound represented by the general formula [IV]. This method includes the step of reacting a vinyl ether with a halogenated acetaldehyde in the presence of an optically active binap... | 12/04/2001 |
| 6307001 | Curable hybrid electron donor compounds containing vinyl ether Hybrid electron donor compounds, suitable for use as adhesives or as components in adhesives, contain a carbon to carbon double bond attached to an aromatic ring and conjugated with the unsaturation in the aromatic ring and a vinyl ether moiety.... | 10/23/2001 |
| 6300456 | Compounds with electron donor and electron acceptor functionality Compounds containing both electron donor and electron acceptor functionality are suitable for use in adhesives. The electron donor group is a carbon to carbon double bond attached to an aromatic ring and conjugated with the unsaturation in the ring. The e... | 10/09/2001 |
| 6258854 | Ketone precursors for organoleptic compounds The invention discloses ketones of formula I: ##STR1## wherein, Y is an optionally substituted alkyl, cycloalkyl, or cycloalkylalkyl, wherein each alkyl group is straight or branched and each alkyl and cycloalkyl group is saturated or unsaturated; R1... | 07/10/2001 |
| 6258836 | Dopamine analog amide The invention involves the formation of a prodrug from a fatty acid carrier and a neuroactive drug. The prodrug is stable in the environment of both the stomach and the bloodstream and may be delivered by ingestion. The prodrug passes readily through the ... | 07/10/2001 |
