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| Number | Title | Issue Date |
| 7223803 | Polyethylene (glycol) derivatives with proximal reactive groups An activated, substantially water soluble poly(ethylene glycol) is provided having of a linear or branched poly(ethylene glycol) backbone and at least one terminus linked to the backbone through a hydrolytically stable linkage, wherein the terminus is branched and h... | 05/29/2007 |
| 7030278 | Polyethylene(Glycol) derivatives with proximal reactive groups An activated, substantially water soluble poly(ethylene glycol) is provided having of a linear or branched poly(ethylene glycol) backbone and at least one terminus linked to the backbone through a hydrolytically stable linkage, wherein the terminus is branched and h... | 04/18/2006 |
| 6998420 | Oxazolidinone compounds Methods of synthesizing pharmacologically useful oxazolidinones are disclosed, and, in particular, a method of manufacturing a 5-(tert-butylcarbamoyl)-aminomethyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamin... | 02/14/2006 |
| 6548679 | Antitumor agents The present invention provides compounds of general formula I or II: ##STR1## wherein R1, R2, R3, R4, R5, R6, and R7 have any of the values defined in the specification, and pharmaceu... | 04/15/2003 |
| 6515137 | Catalytic processes employing chiral imidazolidinone-based catalyst composition Acid addition salts of imidazolidinones are provided as catalysts for transforming a functional group within a first reactant by reaction with a second reactant. Exemplary first reactants are ,ଲ-unsaturated carbonyl compounds such as ,... | 02/04/2003 |
| 6451940 | Catalysts for olefin polymerizations Selected nickel complexes of the anions of certain 2-aminotropones are olefin polymerization catalysts. Novel 2-aminotropones and their nickel complexes are also disclosed together with methods of making these 2-aminotropones. Suitable complexes have the ... | 09/17/2002 |
| 6437025 | Poly(ethylene glycol) derivatives with proximal reactive groups An activated, substantially water soluble poly(ethylene glycol) is provided having of a linear or branched poly(ethylene glycol) backbone and at least one terminus linked to the backbone through a hydrolytically stable linkage, wherein the terminus is bra... | 08/20/2002 |
| 6362254 | Poly(ethylene glycol) derivatives with proximal reactive groups An activated, substantially water soluble poly(ethylene glycol) is provided having of a linear or branched poly(ethylene glycol) backbone and at least one terminus linked to the backbone through a hydrolytically stable linkage, wherein the terminus is bra... | 03/26/2002 |
| 6291702 | Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping... | 09/18/2001 |
| 6255522 | Process for reducing -amino ketones The present invention has its objects to provide a method for reducing -aminoketone derivatives under mild conditions with high stereoselectivity. This invention is a method for reducing -aminoketone which comprises reacting an a-aminoketone... | 07/03/2001 |
| 6197825 | Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping... | 03/06/2001 |
| 6143931 | Synthesis and use of -ketoamide derivatives and arrays The invention is based on new methods for making and using compounds and arrays of novel -ketoamides, and the arrays and compounds made by these methods. These novel compounds are potential inhibitors of proteolytic enzymes, particularly cysteine p... | 11/07/2000 |
| 6114493 | Phosgenated oxime resins and their preparation This invention relates to methods for preparing novel, solid-phase transfer reagents, specifically phosgenated oxime resins and non-symmetrical ureas, that are useful as supports in combinatorial synthesis for the creation of libraries of compounds for le... | 09/05/2000 |
| 6025328 | Antitumor agents The present invention provides illudin analogs of the general formula I: ##STR1## wherein R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, and pharmaceuticall... | 02/15/2000 |
| 5852160 | Phosgenated oxime resins and their preparation This invention relates to methods for preparing novel, solid-phase transfer reagents, specifically phosgenated oxime resins and non-symmetrical ureas, that are useful as supports in combinatorial synthesis for the creation of libraries of compounds for le... | 12/22/1998 |
| 5849866 | Peptidase inhibitors This invention relates to analogs of peptidase substrates in which the amide group containing the scissile amide bond of the substrate peptide has been replaced by an activated electrophilic ketone moiety. These analogs of the peptidase substrates provide... | 12/15/1998 |
| 5814664 | 3-alkylamino-2-hydroxy-4-hydroxymethyl-2-cyclopenten-1-one advanced glycosylation endproducts and methods of use therefor The present invention relates to advanced glycosylation endproducts, and particularly to the use of novel cyclopentenone aminoreductones, 3-alkylamino-2 -hydroxy-4-hydroxymethyl-2-cyclopenten-1-ones. Such AGEs can be used in various diagnostic and therape... | 09/29/1998 |
| 5688653 | 3-alkylamino-2-hydroxy-4-hydroxymethyl-2-cyclopenten-1-one advanced glycosylation endproducts and methods of use therefor The present invention relates to advanced glycosylation endproducts (AGEs), and particularly to novel cyclopentenone aminoreductones, 3-alkylamino-2-hydroxy-4-hydroxymethyl-2-cyclopenten-1-ones. Such AGEs can be used in various diagnostic and therapeutic ... | 11/18/1997 |
| 5519064 | Surface-modified post-crosslinked adsorbents and a process for making the surface modified post-crosslinked adsorbents Disclosed is a surface-modified polymeric adsorbent material comprising a porous post-crosslinked polymer as a substrate and at least one surface-modifying polymer. The porous post-crosslinked polymer comprises a polymer of at least one monoethylenically ... | 05/21/1996 |
| 5514675 | Naphthyl bradykinin receptor antagonists This invention provides methods of treating a physiological disorder associated with an excess of bradykinins in a mammal which comprises administering to a mammal in need of said treatment a compound selected from a series of substituted dihydronaphthale... | 05/07/1996 |
| 5292959 | 4,4-dinitroadamantange-2,6-dione 4,4-Dinitroadamantane-2,6-dione,6, and a method of making the same.... | 03/08/1994 |
| 5180853 | 4,4-6,6-tetronitroadamantan-2-one 4,4,6,6-Tetranitroadamantan-2-one and a method of making the same.... | 01/19/1993 |
| 5164499 | Nitroaryl carbonyl compounds, nitrodihydroaryl carbonyl intermediates thereto, and processes Nitroaryl carbonyl Formula (IIA) compounds, their nitrodihydroaryl carbonyl Formula (I) intermediates, processes for preparing Formula (II) compounds, and a process for preparing Formula (I) compounds, wherein each process comprises the reaction of a nitr... | 11/17/1992 |
| 5164112 | -hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions -hydroxyketone derivatives represented by the general formula (I) which are novel optically active compounds; liquid crystal compositions, such as chiral smectic or chiral nematic compositions, containing the derivatives; and liquid crystal devices... | 11/17/1992 |
| 5131945 | Certain glyoxyl-cyclohexendiones as herbicides Compounds of formula I ##STR1## are useful as herbicides, effective against dicotyledonous weeds.... | 07/21/1992 |
| 5043488 | Process for preparing an explosive and the product therefrom A process for preparing an explosive comprising contacting a ketone with a compound capable of producing a product, or compound, containing nitro groups for a time sufficient to obtain a product having a high-energy content and the product resulting there... | 08/27/1991 |
| 4775411 | Certain substituted 3-amino-2-benzoylcyclohex-2-enones A compound of the formula ##STR1## wherein R is halogen, C1 -C2 alkyl, C1 -C2 alkoxy, nitro; cyano; C1 -C2 haloalkyl, or Ra SOn - wherein n is 0 or 2 and Ra | 10/04/1988 |
| 4681952 | Intermediates in the preparation of 2,2-dimethyl-3-aryl-cyclopropanecarboxylic acids and esters A process for the preparation of 2,2-dimethyl-3-arylcyclopropanecarboxylic acid or ester of the formula ##STR1## in which Ar is naphthyl or the radical ##STR2## R1 is H or C1 -C4 -alkyl, Z is oxygen, sulphur, or ... | 07/21/1987 |
| 4625066 | Substituted acetylene-ketones Novel substituted acetylene-ketones of the formula in which R1 represents optionally substituted cycloalkyl with 4 to 7 carbon atoms or the groupings ##STR1## or represents optionally substituted aryl, if R2 represents optional... | 11/25/1986 |
| 4529813 | Production of insecticidally active vinyl-cyclopropane carboxylic acid esters Insecticidally active vinyl-cyclopropane carboxylic acid esters of the formula ##STR1## are prepared by reacting ##STR2## in which R12 is a radical selected from the group consisting of ##STR3## with an alcoholate of the fo... | 07/16/1985 |
| 4410705 | Novel spiro oxazoline compounds and methods for their preparation and use A process for preparing substituted or unsubstituted benzoxazoline compound by reacting ammonia, a cycloalkanone and oxygen in the presence of metal cations.... | 10/18/1983 |
| 4361704 | Process for preparing m,m'-dinitrobenzophenone A process for preparing m,m'-dinitrobenzophenone which comprises reacting benzophenone with nitric acid in oleum.... | 11/30/1982 |
| 4333952 | Growth promotors for ruminants Compounds of formula (I): ##STR1## wherein: R1 is hydrogen, halogen or C1-4 alkoxy; X is oxygen; NR3 in which R3 is hydrogen, C1-4 alkyl, or -Y-R2 ; --C.dbd.O; or --CHOH; Y is --CH2 | 06/08/1982 |
| 4202822 | 1-Hydroxymethyl-1-oxo-prostane derivatives of the F1 series Derivatives, analogs, and congeners of prostane having a 1-(hydroxymethyl)-1-oxo-prostane structure in the F1 series.... | 05/13/1980 |
| 4163758 | 2-Nitroethylcyclopentane compounds and process for preparing the same 2-Nitroethylcyclopentane compounds represented by the formula (I) ##STR1## wherein X represents a ##STR2## R and R1 each represents a hydrogen atom or a protective group for a hydroxy group, R2 represents an unsubstituted o... | 08/07/1979 |
| 4154611 | Bicyclic reductone developing agents The present invention relates to novel bicyclic compounds useful as photographic silver halide developing agents, to the preparation of these compounds and to photographic products, processes and compositions employing the same. The subject compounds may ... | 05/15/1979 |
| 4154963 | Prostaglandin intermediates Process for synthesizing the lactone, (dl) 3,3a beta-4,5-6,6a beta-hexahydro-4beta(3-hydroxyl-1-trans-octenyl)-5alpha-hydroxy-2-oxo-2H-c yclopenta[b]furan, a known intermediate for producing prostaglandin E2 and F2 and a proce... | 05/15/1979 |
| 4098817 | Oxidation of cycloaliphatic compounds Cyclic compounds, particularly cycloalkanes and cycloalkenes can be oxidized using known metal oxidation catalysts in an organic ester solvent with considerable advantage over prior art solvents. For example cyclohexane was oxidized with a combination cob... | 07/04/1978 |
| 4072716 | Bicycloalkane derivatives Bicycloalkane derivatives of the formula ##STR1## WHEREIN N IS 1 OR 2, R1 is lower alkyl, X is carbonyl or free or etherified hydroxymethylene, and Y is --S--R2, --SOm --R2, or ##STR2## wherein m ... | 02/07/1978 |
| 4051188 | Novel bicycloalkane derivatives and the production thereof Bicycloalkane derivatives of the formula ##STR1## WHEREIN N IS 1 OR 2, R1 is lower alkyl, X is carbonyl or a free or etherified hydroxymethylene, and Y is --S--R2, --SOm --R2, or ##STR2## wherein ... | 09/27/1977 |
