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A method of swing on a swing is disclosed, in which a user positioned on a standard swing suspended by two chains from a substantially horizontal tree branch induces side to side motion by pulling alternately on one chain and then the other.
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| Number | Title | Issue Date |
| 7550630 | Process for producing N-(bicyclo[2.2.1]hept-5-en-2-ylmethyl)-1,1,1-trifluoromethanesulfonamide A process for producing N-(bicyclo[2.2.1]hept-5-en-2-ylmethyl)-1,1,1-trifluoromethanesulfonamide represented by formula [3]. The process includes the step of reacting trifluoromethanesulfonic anhydride with 1-bicyclo[2.2.1]hept-5-en-2-ylmethanamine in the presence o... | 06/23/2009 |
| 7423154 | Asymmetric process for the preparation of diarylethylpiperazines derivatives and novel asymmetric diarylmethylamines as intermediates An asymmetric synthesis of diarylmethylpiperazines is described. The synthetic route enables preparation of a variety of enatiomerically pure amines with different N-alkyl groups. The invention includes an asymmetric addition of organometallic compounds to chiral su... | 09/09/2008 |
| 7388031 | Cyclohexyl(alkyl)-propanolamines, preparation method and pharmaceutical compositions containing same The present invention relates to the compounds of formula (I): in which A is a group of formula (a) or (b) in which R represents a hydrogen or halogen atom, an —S(O)z... | 06/17/2008 |
| 7365196 | Sulphonamido-substituted bridged bicycloalkyl derivatives A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease. ... | 04/29/2008 |
| 7321001 | Asthma and allergic inflammation modulators Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of inflammatory and immune-related diseases and conditions. In particular, the invention provides compounds which modulate the function and/or expression of proteins inv... | 01/22/2008 |
| 7321063 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. T... | 01/22/2008 |
| 7312248 | Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives Novel trifluoromethanesulfonanilide oxime ether compounds useful for controlling endo and/or ectoparasites in the environment are provided, together with methods of making the same, and methods of using the inventive compounds to treat parasite infestations in vivo ... | 12/25/2007 |
| 7169952 | Process to prepare sulfonamides A process for the preparation of a sulfonamide of formula (II), comprising reacting at elevated temperature an aniline of formula (I), with a sulfonating agent A of the formula R1—SO2-Z in the presence of a catalytic amount of either: (i) an ... | 01/30/2007 |
| 7135487 | Sulphonamide derivatives The present invention relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them. ... | 11/14/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 6998423 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders includ... | 02/14/2006 |
| 6927224 | Selective estrogen receptor modulators The present invention provides, inter alia, triphenylethylene derivatives, such as, 3-{4-[6-(3-Methoxy-phenyl)-8,9-dihydro-7H-benzocyclohepten-5-yl]-phenyl}-acrylic acid, as selective estrogen receptor modulators. Also provided are methods for the treatment and/or p... | 08/09/2005 |
| 6911476 | Sulfonamide derivatives The present invention provides certain sulfonamide derivatives useful for potentiating glutamate receptor function in a patient and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders. ... | 06/28/2005 |
| 6908947 | Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them The present invention relates to compounds of formula I, in which X1, X2, X3, X4, Y1, Y2, Y3, Y4, R(3), R(4) and R(5) have the meanings mentioned in the specification, their preparation and their use, in particular in ... | 06/21/2005 |
| 6891065 | Advanced route for the synthesis of cPLA2 inhibitors A process for making a compound of formula (I) in which process the compound HC≡C—(CH2)n—NH2 is reacted with the compound R1—SO2Cl to produce an intermedia... | 05/10/2005 |
| 6803484 | Sulfonamide derivatives The present invention relates to a compound of formula (Ia) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders. ... | 10/12/2004 |
| 6713516 | Sulphonamide derivatives The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them. ... | 03/30/2004 |
| 6583318 | Method for synthesis of -sulfonamido amide, carboxylic acid and hydroxamic acid derivatives A method of synthesizing -sulfonamido amide, carboxylic acid or hydroxamic acid derivatives comprising providing a set of polymer-bound reactant(s) (sulfonamide, aldehyde or ketone, isocyanide or acid) to react with three sets of the other three re... | 06/24/2003 |
| 6573278 | Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases The present invention relates to new aryl ether sulphonamides and analogues, processes for their preparation and their use for the treatment of neurodegenerative disorders, in particular for the prophylaxis and treatment of neurodegenerative disorders, in... | 06/03/2003 |
| 6541422 | Method for improving the selectivity of 1,3-cyclohexanedione herbicide A method of selectively controlling undesirable vegetation in crops by using a postemergent application of an herbicidally effective amount of a metal chelate of a 2-(substituted benzoyl)-1,3-cyclohexanedione compound to the locus of such undesirable vege... | 04/01/2003 |
| 6538159 | -sulfin-and -sulfonamino acid amides The invention relates to -sulfin- and -sulfonamino acid amides of the general formula I ##STR1## including the optical isomers thereof and mixtures of such isomers, wherein n is a number zero or one; R1 is C1 -C12... | 03/25/2003 |
| 6538016 | -sulfin-and -sulfonamino acid amides The invention relates to -sulfin- and -sulfonamino acid amides of the general formula I ##STR1## including the optical isomers thereof and mixtures of such isomers, wherein n is a number zero or one; R1 is C1 -C12... | 03/25/2003 |
| 6485927 | Method for quantitatively determining bicarbonate ion in liquid and dry analysis device This invention provides a method for the determination of bicarbonate ion existing in liquid using phosphenolpyruvate carboxylase and malate dehydrogenase as conjugate enzyme wherein thioNAD(P)H is used as substrate of malate dehydrogenase. The use of the... | 11/26/2002 |
| 6482859 | Microbicidal N-sulfonylglycin alkynyloxyphenethyl amide derivatives The invention relates to novel pesticidally active compounds of the general formula I ##STR1## as well as possible isomers and mixtures of isomers thereof, wherein n is a number zero or one; and R1 is C1 -C12 alkyl that is unsu... | 11/19/2002 |
| 6469005 | Propargylether derivatives Propargylether derivatives of formula I ##STR1## including the optical isomers thereof and mixtures of such isomers, wherein R1 is hydrogen, alkyl, cycloalkyl or optionally substituted aryl, R2 and R3 are each independently hydrogen... | 10/22/2002 |
| 6358981 | Sulphonamide derivatives The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing th... | 03/19/2002 |
| 6333349 | Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them The present invention relates to compounds of formula I, ##STR1## in which X1, X2, X3, X4, Y1, Y2, Y3, Y4, R(3), R(4) and R(5) have the meanings mentioned in the specification, their preparation and their use, in particular in pharmaceuticals. The compoun... | 12/25/2001 |
| 6297398 | Method for the synthesis of perfluorosulphonamides, perfluorosulphonamides and their salts, and a sulphonation reagent The invention concerns a method of sulphonation characterised in that it consists in contacting a nucleophile whose nucleophilic atom is a nitrogen atom with a reagent comprising by successive or simultaneous addition: a heavy sulphonyl halide (i.e. whose... | 10/02/2001 |
| 6284795 | Sulfonamide compounds and methods of treating atherosclerosis and restenosis The present invention provides compounds having the Formula I ##STR1## The present invention also provides methods of treating or preventing atherosclerosis, coronary heart disease, and restenosis using the compounds of Formula I, and pharmaceutical compo... | 09/04/2001 |
| 6277849 | N-sulphonyl and N-sulphinyl amino acid amides as microbiocides The invention relates to novel pesticidally active compounds of the general formula I ##STR1## as well as possible isomers and isomeric mixtures thereof, wherein n is a number zero or one; and R1 is C1 -C12 alkyl that is unsubs... | 08/21/2001 |
| 6271419 | Process and reagent useful for the synthesis of sulphanilide which is perhalogenated on the carbon borne by the sulphur atom of the sulphanilide function The present invention relates to a process and a reagent useful for the synthesis of sulphanilide which is perhalogenated on the carbon borne by the sulphur atom of the sulphanilide function. This persulphonylation process is characterized in that it comp... | 08/07/2001 |
| 6221888 | Sulfonamides as cell adhesion inhibitors Compounds of Formula I are antagonists of VLA-4 and/or 댔ଲ.sub.7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical ... | 04/24/2001 |
| 6197987 | Polyfunctional perhalogenated polyorganosiloxanes and the processes for their preparation The present invention relates to chemically stable, polyfunctional, perfluorinated polyorganosiloxanes (POS) comprising on the one hand fluorinated lateral grafts resulting from the hydrosilylation of perfluorinated olefins with SiH units and having alkyl... | 03/06/2001 |
| 6068989 | Method and dry analytical element for determination of bicarbonate ion in liquid This invention provides a reagent composition for the determination of bicarbonate ion capable of measuring in a wide determination range in visible light region which comprises a combined substrate of thioNAD(P)H and NAD(P)H for a coupled enzymes of phos... | 05/30/2000 |
| 6004948 | Derivatives of benzosulphonamides as inhibitors of the enzyme cyclooxygenase II Compounds of the formula (I) in which A is oxygen, sulphur or NH; B is a group of the formula (IIa) or (IIb); and the other variables have the meaning given in claim 1, may be used as inhibitors of the enzyme cyclooxygenase II ##STR1##... | 12/21/1999 |
| 5849945 | Aminotetralone derivatives and preparation process thereof The present invention pertains to a process for the preparation of Compound (4) through the below-described reaction route: ##STR1## wherein R1 and R2 each represents H, halogen, OH or C1-6 alkyl group; X and Y each r... | 12/15/1998 |
| 5776984 | Prostaglandin synthase-2 inhibitors The present invention provides a compound of the formula: ##STR1## Such compounds are useful for inhibiting prostaglandin synthesis. Pharmaceutical compositions and methods for inhibiting prostaglandin synthesis are also disclosed.... | 07/07/1998 |
| 5599982 | Process for preparing enantiomerically pure imidazo[4,5,1-JK][1,4]-benzodiazepin-2(1H)-thiones Process for preparing enantiomerically pure imidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-thiones of formula ##STR1## starting from 2,6-dihalo-3-nitrobenzyl derivatives (II) and suitably N-protected 1,2-diaminopropanes (III) ##STR2## Novel enan... | 02/04/1997 |
| 5587513 | Polyether-substituted imide compounds and their use The present invention relates to novel polyether-substituted compounds of imides and their use as surface-active agents.... | 12/24/1996 |
| 5545669 | Anti-inflammatory compounds This invention relates to the novel compounds and pharmaceutical compositions of Formula (I). This invention also relates to a method of treating or reducing inflammation in a mammal in need thereof, which comprises administering to said mammal an effecti... | 08/13/1996 |
