Did You Know...
...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Number | Title | Issue Date |
| 8058474 | Urea derivative and process for preparing the same A process for preparing a compound (C) represented by the following formula: wherein R1 represents hydrogen, C1-6 alkyl or C3-8 cycloalkyl, and R2 represents hydrogen or methox... | 11/15/2011 |
| 7423175 | Hydroxy-tetrahydro-naphthalenylurea derivatives This invention relates to hydroxy-tetrahydro-naphthalenylurea derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalenylurea derivatives of the present invention have an excellent activity... | 09/09/2008 |
| 7291744 | N-ureidoalkyl-amino compounds as modulators of chemokine receptor activity The present application describes modulators of chemokine receptors of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases. ... | 11/06/2007 |
| 7115664 | Peptidomimetic ligands for cellular receptors and ion channels One aspect of the present invention relates to novel peptidomimetic compounds. A second aspect of the present invention relates to the use of the novel peptidomimetic compounds as ligands—agonists or antagonists—for various cellular receptors, e.g., G-protein-co... | 10/03/2006 |
| 7105567 | 3-substituted urea derivatives and medicinal use thereof The present invention relates to a urea derivative of the formula (1) wherein each symbol is as described in the specification, a pharmaceutically acceptable salt thereof and pharmaceutical use thereof. The compo... | 09/12/2006 |
| 6962945 | N-aryloxypropanolyl-N′-phenethyl-urea The present invention provides N-aryloxypropanolyl-N′-phenethyl-urea derivatives of formula 3, method for their preparation and use thereof as potent appetite suppressants for treatment of obesity wherein R is select... | 11/08/2005 |
| 6924311 | Methods for affecting various diseases utilizing LXR compounds The present invention relates to methods for elevating high density lipoprotein (HDL) plasma levels, decreasing the absorption of dietary cholesterol in the intestine, decreasing the plasma level of low density lipoprotein (LDL), and increasing the conversion of cho... | 08/02/2005 |
| 6908934 | Therapeutic compounds for treating dyslipidemic conditions Compounds of Formula I and the pharmaceutically acceptable salts and esters thereof, wherein Z is selected from the group consisting of: (a) Formula Ia | 06/21/2005 |
| 6864380 | Benzylcycloalkyl amines as modulators of chemokine receptor activity The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of inflammatory diseases such as asthma and other allergic diseases. | 03/08/2005 |
| 6777561 | Compounds Compounds of general formula I are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comprising the novel compounds and their use in therapy... | 08/17/2004 |
| 6774233 | Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents Disclosed are novel processes and novel intermediate compounds for preparing aryl- and heteroaryl-substituted urea compounds of the formula(I) wherein Ar1, Ar2, L, Q and X are described herein. The product compounds are useful in pharmaceutic c... | 08/10/2004 |
| 6696487 | Fungicidal phenyl(thio)urea and phenyl(thio)carbamate derivatives The invention relates to compounds of formula (I), and also to salts thereof, which have fungicidal activities: ##STR1## in which the various radicals and substituents are as defined in the description, and also to the fungicidal compositions containing t... | 02/24/2004 |
| 6670400 | Phenoxyethylamine derivatives having high affinity for the 5-HT1A receptor, preparation thereof, use thereof as drugs, and pharmaceutical compositions containing said derivatives Phenoxyethylamine derivatives of general formula (I) having high affinity for the 5-HT1A receptor, methods for preparing same, pharmaceutical compositions containing said derivatives, and their use, in particular as gastric acid secretion inhib... | 12/30/2003 |
| 6608227 | Benzylcycloalkyl amines as modulators of chemokine receptor activity The present application describes modulators of CCR3 of formula (I): ##STR1## or pharmaceutically acceptable salt forms thereof, useful for the prevention of inflammatory diseases such as asthma and other allergic diseases.... | 08/19/2003 |
| 6583282 | Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents Disclosed are novel processes and novel intermediate compounds for preparing aryl- and heteroaryl-substituted urea compounds of the formula (I) wherein Ar1, Ar2, L, Q and X are described herein. The product compounds are useful in ph... | 06/24/2003 |
| 6531499 | Matrix metalloproteinase inhibitors and method of using same Peptoid compounds of Formula I and Formula II are disclosed ##STR1## The compounds are useful in the treatment of matrix metalloproteinase-mediated disorders.... | 03/11/2003 |
| 6458998 | Naphthalene ureas as glucose uptake enhancers Compounds of formula I are useful for treating conditions associated with hyperglycemia, especially Type II diabetes. These compounds are useful in stimulating the kinase activity of the insulin receptor, activating the insulin receptor, and stimulating t... | 10/01/2002 |
| 6423854 | Aminophenol derivatives and their use in cosmetics Use of at least one aminophenol derivative of formula (I) below: ##STR1## in which: R represents a hydrogen atom or a radical --COR2, wherein R2 represents a saturated or unsaturated, linear, cyclic or branched, optionally hydroxylated, C... | 07/23/2002 |
| 6372933 | Process for preparing certain phenyl urea compounds This invention relates to a process for making certain phenyl urea compounds by using a Lewis acid to effect the ring opening of a benzoxazolinone by an amine.... | 04/16/2002 |
| 6316503 | LXR modulators The invention provides compounds, compositions and methods for modulating the effects of LXR in a cell. The compounds and compositions are useful both as diagnostic indicators of LXR function and as pharmacologically active agents. The compounds and compo... | 11/13/2001 |
| 6294694 | Matrix metalloproteinase inhibitors and method of using same Peptoid compounds of Formula I and Formula II are disclosed ##STR1## The compounds are useful in the treatment of matrix metalloproteinase-mediated disorders.... | 09/25/2001 |
| 6214880 | Arylsulfonanilide ureas The invention provides compounds, compositions and methods relating to novel arylsulfonanilide derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states,... | 04/10/2001 |
| 6133319 | IL-8 receptor antagonists This invention relates to the use of phenyl ureas of formulas (I) and (II) in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8). The variables of (I) and (II) are defined herein. ##STR1##... | 10/17/2000 |
| 6127423 | Phenylamidine derivatives, a process for preparing the same and their use as medicaments The invention relates to new phenylamidine derivatives, processes for preparing them and their use as pharmaceutical compositions. The phenylamidines according to the invention correspond to the general formula I ##STR1##... | 10/03/2000 |
| 6075049 | Phenylcarbamates, processes and intermediate products for their preparation and their use as pesticides and fungicides Phenylcarbamates of the formula I ##STR1## where the substituents and the index have the following meanings: R is cyano, nitro, trifluoromethyl, halogen, alkyl or alkoxy; m is 0, 1 or 2; R1 is alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkenyl... | 06/13/2000 |
| 6043284 | Anti-atherosclerotic diaryl compounds The present invention is concerned with diaryl compounds of formula (I) and their use in medical therapy, particularly in the prophylaxis or treatment of a clinical condition for which an ACAT inhibitor is indicated, such as hyperlipidaema or atherosclero... | 03/28/2000 |
| 6005008 | IL-8 receptor antagonists This invention relates to the novel use of phenyl ureas in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).... | 12/21/1999 |
| 5977399 | Iminooxymethyleneanilides, preparation thereof and intermediates therefor, and compositions containing them Iminooxymethyleneanilides of the formula I ##STR1## where the substituents and the index have the following meanings: R is hydrogen, unsubst. or subst. alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, alkylcarbonyl or alkoxycarbonyl; ... | 11/02/1999 |
| 5972964 | Aminomethylindans, -benzofurans and -benzothiophenes Compounds of formula I ##STR1## wherein R1.dbd.(cyclo)alk(en)yl, aralkyl, alkyl(oxy)carbonyl, CONH2, etc.; R2.dbd.H, (cyclo)alk(en)yl, aralkyl, etc.; R3-R5.dbd.H, halo, alkyl, alkoxy, etc.; R6,R7.dbd.H, alkyl; R6R7.dbd.atoms to complete a ring; ... | 10/26/1999 |
| 5952386 | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are indepen... | 09/14/1999 |
| 5849732 | Phenol compound having antioxidative activity and the process for preparing the same Disclosed are a phenol compound represented by the formula (1): ##STR1## wherein R0 represents H, alkyl or alkyloxy; R1 represents alkyl; R2 represents alkyl or alkyloxy; OR3 represents OH; R4 re... | 12/15/1998 |
| 5824705 | Carbamates and crop protection agents containing them Carbamates of the formula I ##STR1## where the substituents have the following meanings: Z is methoxy, NH2, NHCH3, N(CH3)2, CH3, C2 H5, CF3 or CCl3, X ... | 10/20/1998 |
| 5728874 | Anti-HIV achiral polyurea oligomers, a process for creating them, formulations using them, and their use in the treatment of AIDS The present invention relates to achiral polyurea oligomers, their uses and formulations as anti-HIV pharmaceuticals and to a process for the preparation of narrow mono- and polydispersed oligomers as an emodiment of the invention. The achiral oligomers a... | 03/17/1998 |
| 5714633 | Process for the preparation of arylalkynyl-N-hydroxyurea derivatives having lipoxygenase inhibitory activity The present invention provides a process for the preparation of a compound of formula ##STR1## wherein R is a straight or branched alkyl group of from one to twelve carbon atoms; M represents hydrogen or a pharmaceutically acceptable cation; and... | 02/03/1998 |
| 5696138 | Urea derivatives and their use A compound having the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein X, Z, Y, A, D, E, F, R1, R2, R3, R4, R11, R12 have the meanings set forth in the specification,... | 12/09/1997 |
| 5681858 | Cycloalkyl hydroxyureas The present invention provides a novel N-hydroxyurea compound of chemical formula (I) wherein R1 and R2 are each independently hydrogen or C1 -C4 alkyl; Ar is phenyl or mono-, di- or trisubstituted phenyl; A is ... | 10/28/1997 |
| 5668136 | Trisubstituted benzene derivatives, composition and methods of treatment A benzene, pyridine or pyrimidine derivative having the below shown formula is novel and useful as an anti-arteriosclerotic agent. ##STR1## wherein R1 stands for a lower alkyl group, an amino group which may be substituted, or the like; R | 09/16/1997 |
| 5621010 | Urea derivatives and their use as ACAT inhibitors Urea derivatives of formula (I) ##STR1## wherein the valuable groups are as defined in the specification, which possess both an ACAT inhibitory activity and an antioxidative activity. Those derivatives are useful in the prophylaxis and treatment of ... | 04/15/1997 |
| 5614550 | Amide and urea derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses Compounds of formula (I) are provided: ##STR1## wherein: R1 represents an alkyl group; or a group of formula (II), (III), (IV) or (V): ##STR2## and wherein the groups R2, R3, R4 and R5 are h... | 03/25/1997 |
| 5585518 | Hydroxyphenylureas Useful ureas have the formula ##STR1##... | 12/17/1996 |
