Pneumatic Shoe Lacing Apparatus
This invention provides a pneumatic shoe lacing apparatus for the pneumatic lacing of shoe.
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| Number | Title | Issue Date |
| 8067641 | Synthesis of triethylenetetramines Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity. ... | 11/29/2011 |
| 7491849 | Oligoamine compounds and derivatives thereof for cancer therapy Oligoamine compounds with anti-cancer and anti-proliferative activity are provided, as well as methods for making and using the compounds. The compounds are shown to be active against prostate cancer cell lines and against prostate cancer tumors in mice. The compoun... | 02/17/2009 |
| 7423182 | Aminated polyamines An aminated polyamine having the formula: or its possible stereoisomers or a salt thereof with a pharmaceutically acceptable acid wherein: R1 and R4 may be the same o... | 09/09/2008 |
| 7414154 | Polyamine compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-effects of chemoth... | 08/19/2008 |
| 7393978 | Method for producing ethylene-amines Process for the preparation of ethylenamines, in particular diethylenetriamine (DETA), by continuous reaction of ethylenediamine (EDA) in the presence of a heterogeneous catalyst, where the reaction is carried out in a reaction column. ... | 07/01/2008 |
| 7388112 | Immunomodulation with novel pharmaceutical compositions The synthesis and use of a novel class of tumor necrosis factor (TNFα) inhibitors and immunomodulators are provided. Examples are those having the structures: wherein a, b and c are integers from 0 to 12, X equals NH or CH... | 06/17/2008 |
| 7364668 | Process for producing an amino composition The present invention provides a process for producing an amino composition by addition reaction between a polyamine and an unsaturated hydrocarbon compound in the presence of a strongly basic alkali metal catalyst to obtain an amino composition containing not more ... | 04/29/2008 |
| 7335795 | Crosslinked amine polymers The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides polymeric and pharmaceutical compositions comprising crosslinked amine polymers. Methods of use of the polymeric and pharmaceutical com... | 02/26/2008 |
| 7323594 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/29/2008 |
| 7314959 | Amino thiol compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine and amino thiol compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-ef... | 01/01/2008 |
| 7279502 | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions... | 10/09/2007 |
| 7273888 | Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis The present invention provides methods and compositions for modulating polyamine pathway activity as a means for ameliorating neurodegenarative disorders. In particular, for ameliorating the symptoms or onset of amyotrophic lateral sclerosis (ALS) by modulating the ... | 09/25/2007 |
| 7166745 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/23/2007 |
| 7094808 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment Polyamines having the formula: or a salt thereof with a pharmaceutically acceptable acid wherein: R1-R6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally having ... | 08/22/2006 |
| 7091338 | Purification of 4,4′(5′)- di-t-butylcyclohexano-18-crown-6 A purification method is disclosed for a predetermined water-insoluble extractant present in a liquid phase composition that additionally contains one or more additional extractants, synthesis reaction starting materials, and reaction byproducts dissolved as solutes... | 08/15/2006 |
| 7045550 | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy Polyamine effectors are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical preparations comprising one or more polyamine effectors formulated fo... | 05/16/2006 |
| 7022214 | Carrier ampholytes of high pH range Carboxylic acid-substituted polyalkylene polyamines in which amine nitrogen atoms on the polyamine backbone structure are replaced by guanidine groups provide a pH range extending into high pH values. These substances are useful as carrier ampholytes in isoelectric ... | 04/04/2006 |
| 7002042 | Cationic liposomes for gene transfer The present invention relates to synthetic cationic lipids, liposome formulations and the use of such compounds to introduce functional bioactive agents into cultured cells. ... | 02/21/2006 |
| 6949679 | Polyamine transport inhibitors The present invention describes the design, synthesis and therapeutic use of a variety of novel inhibitors of polyamine transport. The main feature of this class of transport inhibitors is to incorporate a linker or side chain that prevents the uptake of polyamines ... | 09/27/2005 |
| 6919483 | Immunomodulation with novel pharmaceutical compositions The synthesis and use of a novel class of tumor necrosis factor (TNFα) inhibitors and immunomodulators are provided. These compounds have pharmacological applications as well as uses in assays relating to TNFα and other involved cytokines. As pharmaceuticals, thes... | 07/19/2005 |
| 6762325 | Method for production of alkoxylated compound When the reaction solution formed during the addition of an alkylene oxide to an active hydrogen-containing compound has viscosity of not less than 10 mPa·s, this invention provides a method for stirring the reaction solution by the rotation of a vane or vanes cont... | 07/13/2004 |
| 6716882 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transfor... | 04/06/2004 |
| 6713653 | Polyamines and polymers made therewith A polyamine having the formula: H2N—A[NR—B]aNH2 or salt thereof, wherein A and B, which may be the same or different, are selected from aliphatic or aromatic substituents provided that at least fou... | 03/30/2004 |
| 6673192 | Multi-amine compound primers for bonding of polyolefins with cyanoacrylate adhesives Primers for cyanoacrylate adhesives which are based on compounds having multiple amine groups thereon ("multi-amines") which have at least three secondary or tertiary amine groups, at least one of which is a tertiary amine group. The multi-amine compounds... | 01/06/2004 |
| 6667382 | Polyamine The present invention provides an amine or polyamine, which has a surface activity not inferior to a solid tallow-based amine and an excellent workability. A salt of the amine is suited for emulsifying asphalt and the like, and also provides an asphalt em... | 12/23/2003 |
| 6649587 | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as c... | 11/18/2003 |
| 6605645 | Linear polyamine compounds and polyamine-based anti-tumor agents Nobel polyamine compounds and polyamine compounds having carcinostatic action are provided. There are also provided anticancer agents containing as active ingredient at least one of polyamine compounds represented by the following Formula (I) or (III) and... | 08/12/2003 |
| 6492560 | Discrete-length polyethylene glycols The present invention provides discrete-length polyethylene glycol and polyethylene glycol containing compounds and methods for their preparation.... | 12/10/2002 |
| 6472426 | Sterically hindered tetraamines and method for their production Polyamines having the formula: ##STR1## wherein R1 and R2 are alkyl, aralkyl or aryl having up to 10 carbon atoms; and a and b may be the same or different and are integers from 1 to 8; or a salt thereof with a pharmaceutically accep... | 10/29/2002 |
| 6455591 | Polyamines and anti-diarrheal and gastrointestinal anti-spasmodic pharmaceutical compositions and methods of treatment Anti-diarrheal, anti-secretory, nitric oxide agonist, nitric oxide synthase activating or gastrointestinal anti-spasmodic compounds of the formula: ##STR1## R1 --N1 H--(CH2)3 --N2 H--(C2) | 09/24/2002 |
| 6441240 | Method for inhibiting the deposition of white pitch in paper production Ethyleneamine compound(s), or mixtures thereof, are used in effective amounts to reduce or inhibit the deposition of white pitch on the paper making equipment during the processing to recycle coated paper.... | 08/27/2002 |
| 6417356 | Stabilization of vinylether and vinyl lactam formulations against hydrolysis This invention relates to a composition containing (a) a component selected from the group of a mono- or poly- vinyl substituted mono- or poly-ether, a mono- or poly- vinyl substituted lactam, or a mixture thereof contained in an acidic medium and (b) an ... | 07/09/2002 |
| 6399663 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-depende... | 06/04/2002 |
| 6362232 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of insects.... | 03/26/2002 |
| 6342534 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment Polyamines having the formula: ##STR1## or a salt thereof with a pharmaceutically acceptable acid wherein: R1 -R6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally having an alkyl chain interrupted by at... | 01/29/2002 |
| 6319956 | Linear polyamine compounds and polyamine based anti-tumor agents Nobel polyamine compounds and polyamine compounds having carcinostatic action are provided. There are also provided anticancer agents containing as active ingredient at least one of polyamine compounds represented by the following Formula (I) or (III) and... | 11/20/2001 |
| 6294697 | Discrete-length polyethylene glycols The present invention provides discrete-length polyethylene glycol and polyethylene glycol containing compounds and methods for their preparation.... | 09/25/2001 |
| 6281371 | Lipopolyamines, and the preparation and use thereof The present invention relates to new lipopolyamines (including salts thereof) characterised by a symmetrical, highly flexible lipophilic moiety having buffering capacity at physiological pH, and to the use thereof for the in vivo or in vitro introduction ... | 08/28/2001 |
| 6262125 | Sterically hindered tetraamines and method for their production Polyamines having the formula: ##STR1## wherein R1 and R2 are alkyl, aralkyl or aryl having up to 10 carbon atoms; and a and b may be the same or different and are integers from 1 to 8; or a salt thereof with a pharmaceutically acceptable... | 07/17/2001 |
| 6258976 | Process for the preparation of polyamines and polyamine derivatives Disclosed are processes for the preparation of compounds of the formula (I): H2N--(CH2)n--A--(CH2)m--NH2, or (II): H2N--(CH2)n--NH--C(.dbd.NR1)--NH--(CH2)m--NH2, wherein n and m are each independently an integer from 2 to 8; A is selected from the group ... | 07/10/2001 |