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| Number | Title | Issue Date |
| 7473806 | Modified chain aliphatic polyamine A modified chain aliphatic polyamine obtained by addition reaction of a chain aliphatic polyamine having a specific structure and an unsaturated hydrocarbon compound has a low viscosity and it provides, when used as a curing agent for epoxy resin, an epoxy resin com... | 01/06/2009 |
| 7414154 | Polyamine compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-effects of chemoth... | 08/19/2008 |
| 7323594 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/29/2008 |
| 7314959 | Amino thiol compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine and amino thiol compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-ef... | 01/01/2008 |
| 7279071 | Paper articles exhibiting water resistance and method for making same This invention relates to a process for preparing sized paper and paperboard which incorporates in the paper and paperboard at the size press size a composition comprising one or more “hydrophobic polymers” wherein hydrophobic polymers, the amount of such polyme... | 10/09/2007 |
| 7196226 | Fluoraminoolefins and fluorination reagents which can be prepared therefrom The present invention relates to fluorination reagents comprising 1-fluoro-1-aminoolefins and also processes for preparing fluorination reagents comprising 1-fluoro-1-aminoolefins. ... | 03/27/2007 |
| 7189680 | 5-halo-6-aryl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines The invention relates to novel triazolopyrimidines of the formula in which R1, R2, R3 and X have the meanings given in the disclosure, and acid addition s... | 03/13/2007 |
| 7166745 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/23/2007 |
| 7164034 | Alpha2delta ligands for fibromyalgia and other disorders This invention relates to a method of treating a disorder selected from OCD, agoraphobia, agoraphobia without history of panic disorder, specific phobia, social phobia, PTSD, restless legs syndrome, premenstrual dysphoric disorder, hot flashes, and fibromyalgia by a... | 01/16/2007 |
| 7160838 | Metal oxide-coated SiC foam carriers for catalysts, and catalytic systems therefor A catalyst carrier including a surface layer of oxygen-donating oxide, particularly cerine, is disclosed. A catalytic phase deposited on said carrier generally includes platinum and rhodium, thus forming a catalytic system for exhaust pipes, said catalytic phase bei... | 01/09/2007 |
| 7078567 | Amination process The present invention provides methodology for carbon-nitrogen bond formation via vinyl or aryl amination. In the process of the invention, an sp2 hybridized radical is reacted with an azomethine moiety to form pyrrolidine and indole compounds. The method... | 07/18/2006 |
| 7002042 | Cationic liposomes for gene transfer The present invention relates to synthetic cationic lipids, liposome formulations and the use of such compounds to introduce functional bioactive agents into cultured cells. ... | 02/21/2006 |
| 6951962 | Oil/grease- and water-sizing agent for treatment of cellulosics A water-dispersible oil/grease-sizing and water-sizing agent that provides oil/grease and water-sizing for paper and other cellulosic materials. The agent works effectively for both oil/grease and water sizing at high temperatures. The polymeric agent's key features... | 10/04/2005 |
| 6939554 | Antimicrobial polymer A polymeric composition having antimicrobial properties and a process for rendering the surface of a substrate antimicrobial are disclosed. The composition comprises a crosslinked chemical combination of (i) a polymer having amino group-containing side chains along ... | 09/06/2005 |
| 6924396 | α-haloenamine reagents The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use. ... | 08/02/2005 |
| 6908948 | DNA-cleaving antitumor agents A chemical composition and method of use of the composition is described. The chemical composition includes an aza-enediynes, aza-enyne allenes, or an aza-diallenes. These compound are preferably non-hydrolyzable, cationic compounds that bind to nucleic acids. In ad... | 06/21/2005 |
| 6852892 | Process for the synthesis of sphingosine This invention relates to a method for the production of a sphingoid base according to formula comprising the steps of (1) dissolving a starting compound according to formula III or a salt thereof in a sub... | 02/08/2005 |
| 6794545 | Conformationally restricted polyamine analogs as disease therapies Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of d... | 09/21/2004 |
| 6773928 | Compositions and methods for enhancing bioassay performance Compositions of matter and methods for enhancing bioassay performance are disclosed. More particularly, the composition of matter comprises a molecularly compact polymer-ligand conjugate capable of self-orienting on a surface to improve the orientation of the ligand... | 08/10/2004 |
| 6774270 | Method of removing hexafluoropropylene dimers A method of removing hexafluoropropylene dimers (“HFP dimers”), dimer hydrides and other oligomers from a fluid is described. The method comprises heating the fluid to isomerize the HFP dimers to the thermodynamic isomer, and contacting the fluid with a tertiary... | 08/10/2004 |
| 6686345 | DNA-cleaving antitumor agents A chemical composition and method of use of the composition is described. The chemical composition includes an aza-enediyne, aza-enyne allene, or an aza-diallene. These compound are preferably non-hydrolyzable, cationic compounds that bind to nucleic acid... | 02/03/2004 |
| 6683181 | Pyrroloquinolones as antiviral agents The present invention provides a compound of formula I ##STR1## which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.... | 01/27/2004 |
| 6677487 | -haloenamine reagents The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use.... | 01/13/2004 |
| 6649587 | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as c... | 11/18/2003 |
| 6642398 | Mono-and disubstituted 3-propyl gamma-aminobutyric acids The instant invention is a series of novel mono- and disubstituted 3-propyl gamma aminobutyric acids of Formula I ##STR1## The compounds are useful as therapeutic agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, ... | 11/04/2003 |
| 6608120 | Diallylamine monomers and network polymers obtained therefrom Compounds of the formula: ##STR1## having two double bonds which are activated so that they will take part in a polymerization reaction, the double bonds being sufficiently close together to ensure that cyclopolymerization will preferentially occur. ... | 08/19/2003 |
| 6458837 | Lipophilic diesters of chelating agents The invention discloses stable diesters of chelating agents of divalent metal ions, processes for their preparation and pharmaceutical compositions thereof. Most preferred compounds according to the present invention are stable lipophilic diesters compris... | 10/01/2002 |
| 6392098 | Conformationally restricted polyamines Compounds of Formula I: E--NH--D--NH--B--A--B--NH--D--NH--E (I) wherein A is C2 -C6 alkene, C3 -C6 cycloalkyl, cycloalkenyl, or cycloaryl; B is independently a single bond, C1 -C6 alkyl alkenyl... | 05/21/2002 |
| 6350910 | Stereospecific isomerisation of allylamines with the aid of immobilized phosphorated chiral ligands The present invention describes a method for stereospecific isomerisation of prochiral allylamines into enamines and chiral imines, by using catalysts of Rh, Ir and Ru having phosphine chiral ligands immobilised on a solid material. The immobilised ligand... | 02/26/2002 |
| 6326499 | Omega chain modified 15-hydroxyeicosatetraenoic acid derivatives and methods of their use for the treatment of dry eye Omega chain modified 15-HETE derivatives and methods of their use for treating dry eye are disclosed.... | 12/04/2001 |
| 6312538 | Chemical compound suitable for use as an explosive, intermediate and method for preparing the compound A new compound, 1,1-diamino-2,2-dinitroethylene suitable for use as an explosive, as well as an intermediate for preparing the compound consisting of a heterocyclic 5- or 6-ring of the general formula ##STR1## wherein n=at least 1. The compound is prepare... | 11/06/2001 |
| 6297284 | DNA-cleaving antitumor agents A chemical composition and method of use of the composition is described. The chemical composition includes an aza-enediyne, aza-enyne allene, or an aza-diallene. These compound are preferably non-hydrolyzable, cationic compounds that bind to nucleic acid... | 10/02/2001 |
| 6258976 | Process for the preparation of polyamines and polyamine derivatives Disclosed are processes for the preparation of compounds of the formula (I): H2N--(CH2)n--A--(CH2)m--NH2, or (II): H2N--(CH2)n--NH--C(.dbd.NR1)--NH--(CH2)m--NH2, wherein n and m are each independently an integer from 2 to 8; A is selected from the group ... | 07/10/2001 |
| 6252116 | Intermediates useful in a process for synthesizing COX-2 inhibitors The invention encompasses a process for making compounds of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1##... | 06/26/2001 |
| 6180784 | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein The present invention provides a process of transfecting a cell with a polynucleotide mixed with one or more amphipathic compounds and an effective amount of a DNA-binding protein. Exemplary and preferred DNA-binding proteins are H1, H2A, and H2B. Exempla... | 01/30/2001 |
| 6156222 | Poly-perfluoroalkyl substituted polyamines as grease proofing agents for paper and foam stabilizers in aqueous fire-fighting foams Perfluoroalkyl-allyloxy- and perfluoroalkyl-iodopropyloxy-substituted polyaminoacids or poly-RF -fluoroallyl-substituted polyaminoacids which contain, in random distribution, q units of A-1, r units of A-2, s units of A-3 and t units of A-4 in ... | 12/05/2000 |
| 6127583 | Process for preparing acetylene derivative from a ketone compound A preparation process of an acetylene derivative comprising reacting a compound having a skeleton represented by the formula (1): ##STR1## in the molecular formula with a compound represented by the formula (2): ##STR2## wherein R1, R... | 10/03/2000 |
| 6020527 | Stereospecific isomerisation of allyl amines using chiral phosphorous ligands The present invention describes a stereospecific process for the isomerization of prochiral allyl amines into chiral enamines and imines, using Rh, Ir or Ru catalysts which carry chiral phosphine ligands derived from ferrocenes, which may be immobilized o... | 02/01/2000 |
| 6013838 | Chemical intermediates bearing a trifluoromethyl group Novel trifluoromethylated intermediates are provided which are useful in synthesizing trifluoromethylated organic compounds. Specifically, compounds of the formula CF3 CR are provided, wherein R is (Cl).dbd.CHCH2 SO2 Ph, (... | 01/11/2000 |
| 6005146 | Stabilized non-polymeric acetoacetate esters that promote adhesion to metallic and oxidized substrates The present invention provides improved adhesion promoters for latex paints. The adhesion promoters are enamines of acetoacetate esters, or substituted acetoacetate esters. The invention also provides two new compounds which are useful as adhesion promote... | 12/21/1999 |
