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| Number | Title | Issue Date |
| 7635791 | Biological buffers with wide buffering ranges Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa'... | 12/22/2009 |
| 7462746 | Amino polyols and amino sugars Synthetic methods provide for the simple, efficient preparation of amino polyols and derivatives. The methods include a three-component reaction of a carbohydrates with organoboron compounds and primary or secondary amine derivatives. The resulting amino polyols can... | 12/09/2008 |
| 7429680 | Synthesis of sterically hindered secondary aminoether alcohols Severely sterically hindered secondary aminoether alcohols are prepared by reacting an organic carboxylic acid or alkali metal salt of an organic carboxylic acid with a sulfonyl halide, a sulfuryl halide, a mixed sulfuryl ester halide or a mixed sulfuryl amide halid... | 09/30/2008 |
| 7414154 | Polyamine compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-effects of chemoth... | 08/19/2008 |
| 7351865 | Synthesis of sterically hindered secondary aminoether alcohols from acid anhydride and/or acid halide and sulfur trioxide Severely sterically hindered secondary aminoether alcohols are prepared by reacting acid anhydrides or organic carboxylic acid halides with SO3 to yield a sulfonic carboxylic anhydride compound which is then reacted with a dioxane to cleave the ring of th... | 04/01/2008 |
| 7323594 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/29/2008 |
| 7166745 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/23/2007 |
| 7129275 | Compositions for treating acne comprising phytandiol amine The present invention relates to a phytandiol amine derivative represented by the following formula (I) and compositions for treating acne comprising the same: wherein each of Y and Z is ... | 10/31/2006 |
| 7060731 | Use of amines This application relates to the use of certain amines of formula (I) for combatting and preventing systemic and local complement activation, and in particular to the use of meglumine and derivatives and optionall... | 06/13/2006 |
| 6852892 | Process for the synthesis of sphingosine This invention relates to a method for the production of a sphingoid base according to formula comprising the steps of (1) dissolving a starting compound according to formula III or a salt thereof in a sub... | 02/08/2005 |
| 6720184 | Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination This invention provides a method of altering the metabolism of sphingolipids in a cell comprising contacting the cell with a fumonisin, or an analog thereof. The invention also provides a method of detecting the consumption of a fumonisin or a fumonisin analog in a ... | 04/13/2004 |
| 6716882 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transfor... | 04/06/2004 |
| 6600075 | Process for the preparation of tertiary amines from primary amines and nitriles Disclosed is a method for preparing tertiary amine compounds from primary amines and nitrites in the presence of hydrogen gas and a metal catalyst, or metal-containing catalyst composition, at a temperature from about 50° C. to about 200° C. and at a pr... | 07/29/2003 |
| 6583182 | Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy and diagnosis This invention involves synthesis and use of a class of compounds with chelation affinity and selectivity for first transition series elements. Administration of the free or conjugated compound, or physiological salts of the free or conjugated compound, r... | 06/24/2003 |
| 6399663 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-depende... | 06/04/2002 |
| 6365778 | Process for the preparation of N-alkypolyhydroxyalkylamines from monoalkylamine and reducing sugar Aqueous, alcoholic or aqueous-alcoholic solutions of a monoalkylamine and a reducing sugar are simultaneously injected into a mixing unit and the two solutions are mixed under turbulence in the mixing unit for 6 seconds to 5 minutes at a temperature of 25... | 04/02/2002 |
| 6329409 | Amine derivatives and skin preparations for external use containing the same The invention relates to an amine derivative represented by the general formula (1): ##STR1## wherein R1 is a C1 -C30 hydrocarbon group which may be interrupted by an ether linkage, with the proviso that phenyl and benzyl ... | 12/11/2001 |
| 6127578 | Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination This invention provides a method of altering the metabolism of sphingolipids in a cell comprising contacting the cell with a fumonisin, or an analog thereof. The invention also provides a method of detecting the consumption of a fumonisin or a fumonisin a... | 10/03/2000 |
| 6031135 | Trimethylsphingosine derivatives The invention relates to trimethylsphingosine derivatives which have some or all of the activities of the parent compound.... | 02/29/2000 |
| 5985239 | Derivatives of N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters The present invention relates to N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters, and their use as agents for water disinfection and as mild oxidizing agents for the radiolabeling of oxidation-sensitive biomolecules.... | 11/16/1999 |
| 5976202 | Reaction products of polyolefins with vinyl esters and their use as fuel and lubricant additives Reaction products of polyolefins having predominantly a terminal double bond and a number average molecular weight of from 250 to 10,000, which possess an aliphatic hydrocarbon skeleton which is straight-chain or carries C1 -C4 -alky... | 11/02/1999 |
| 5929283 | Amine derivative and detergent composition containing the same The present invention relates to an amine derivative represented by the following general formula (1): ##STR1## wherein R2 and R3 mean individually an alkyl or alkenyl group which may have --OH and has 1-24 carbon atoms, A denot... | 07/27/1999 |
| 5922917 | Process for the preparation of 2-amino-1,3-propanediol A process for the preparation of 2-amino-1,3-propanediol comprising the catalytic hydrogenation of 1,3-dihydroxyacetone oxime in the presence of rhodium supported on alumina is described.... | 07/13/1999 |
| 5886228 | Highly purified 1-aminopropanediol-2,3 1-aminopropanediol-2,3 containing 2-aminopropanediol-1,3 of less than 0.30% by weight can be prepared by the present purification process, which comprises distilling a 1-aminopropanediol-2,3 containing at least 0.3% of 2-aminopropanediol-1,3 based on the ... | 03/23/1999 |
| 5866719 | Process for the purification of an aminoalcohol The present invention relates to a process for the preparation of 2-amino-1,3-propanediol, having a content of organic impurities lower than 0.1% and inorganic impurities lower than 0.05%, comprising the following steps: a) formation of a 2-amino-1,3-prop... | 02/02/1999 |
| 5840990 | Intermediates to carbocyclic nucleosides The present invention relates to certain purine nucleoside analogues containing a carbocyclic ring ill place of trip sugar residue, salts, esters and pharmaceutically acceptable derivatives thereof, processes for there preparation, pharmaceutical formulat... | 11/24/1998 |
| 5801202 | Amine derivatives for treatment of skin disorders Disclosed is an amine derivative represented by the following formula (1) or an acid addition salt thereof: ##STR1## wherein R1 represents a group ##STR2## a cyclopentyl group, cyclohexyl group, or a cycloheptyl group, R2 i... | 09/01/1998 |
| 5756558 | Hydroxyalkylbis(aminoethyl) ether compositions for the production of polyurethanes A method for preparing a polyurethane foam which comprises reacting an organic polyisocyanate and a polyol in the presence of a blowing agent, a cell stabilizer and a catalyst composition comprising a compound having the following formula I: ##STR1##... | 05/26/1998 |
| 5753701 | N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters as novel safe agents for water disinfection The present invention relates to N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters, and their use as agents for water disinfection and as mild oxidizing agents for the radiolabeling of oxidation-sensitive biomolecules.... | 05/19/1998 |
| 5750792 | Highly purified 1-aminopropanediol-2,3 1-aminopropanediol-2,3 containing 2-aminopropanediol-1,3 of less than 0.30% by weight can be prepared by the present purification process, which comprises distilling a l-aminopropanediol-2,3 containing at least 0.3% of 2-aminopropanediol-1,3 based on the ... | 05/12/1998 |
| 5723497 | Amine derivative and dermatologic preparation containing the same The present invention relates to an amine derivative represented by the following general formula (I) or (II): ##STR1## wherein R1 means a heteroatom-containing C1 -C40 hydrocarbon group which may have a ring structur... | 03/03/1998 |
| 5681864 | Composition for external skin care A composition for external skin care comprising an amine derivative represented by the following formula (1), ##STR1## wherein R1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R | 10/28/1997 |
| 5600001 | Acetaldehyde derivatives, their preparation process and their use Azines of formula (I): ##STR1## in which R and R' either are identical and represent an alkyl radical containing 1 to 4 carbon atoms or an alkenyl radical containing 3 to 5 carbon atoms, or together form a radical of formula (II): --CHR1 -... | 02/04/1997 |
| 5556516 | Method for the purification of 1-aminopropanediol-2,3 1-aminopropanediol-2,3 containing 2-aminopropanediol-1,3 of less than 0.30% by weight can be prepared by the present purification process, which involves distilling a 1-aminopropanediol-2,3 containing at least 0.3% of 2-aminopropanediol-1,3 based on the w... | 09/17/1996 |
| 5552445 | Composition for external skin care A composition for external skin care comprising an amine derivative represented by the following formula (1), ##STR1## wherein R1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R | 09/03/1996 |
| 5523478 | Carbohydrate-derived surfactants and their precursors A method for the manufacture of N,N dialkylglycamine compounds of general formula R2 NR1 R3 (I) by reacting a secondary amine of general formula R2 NHR3 (II) in which R2 is a straight or br... | 06/04/1996 |
| 5518879 | Method of altering sphingolipid metabolism and detecting fumonisin ingestion and contamination This invention provides a method of altering the metabolism of sphingolipids in a cell comprising contacting the cell with a fumonisin, or an analog thereof. The invention also provides a method of detecting the consumption of a fumonisin or a fumonisin a... | 05/21/1996 |
| 5488166 | Synthesis of sphingosines Provided by the present invention is a process for the biocatalytic synthesis of optically pure sphingosines from achiral starting material. The stereoisomers of sphingosine are prepared from chiral arene diols using stereospecific reaction techniques to ... | 01/30/1996 |
| 5488167 | Synthesis of sphingosines Provided by the present invention is a process for the biocatalytic synthesis of optically pure sphingosines from achiral starting material. The stereoisomers of sphingosine are prepared from chiral arene diols using stereospecific reaction techniques to ... | 01/30/1996 |
| 5475119 | Diallylammonium compounds, processes for their preparation and their use Ionic monomeric diallylammonium compounds having a targeted combination of diallylammonium cations with selected anions have particularly high and constant charge control properties and very good heat stabilities and dispersibilities. The compounds accord... | 12/12/1995 |
