Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7799952 | Stereoselective method for the production of (R)-Dimepranol The present invention relates to processes for preparing a compound of the general formula (Ia) wherein X is a halogen atom, or a pharmaceutically acceptable salt thereof, wherein a compound of the formula (II) | 09/21/2010 |
| 7531693 | Lipids for transfection of nucleic acids Cationic lipid compositions are provided that are useful for efficient delivery of macromolecules, such as nucleic acids, into a wide variety of eukaryotic cell types. Methods for using the compositions also are provided. ... | 05/12/2009 |
| 7495131 | Blowing catalyst compositions containing hydroxyl and surface active groups for the production of polyurethane foams Tertiary amines useful as catalysts for preparing polyurethane foams are provided. Tertiary amines are employed to catalyze the trimerization reaction of isocyanates and the reaction between isocyanates and active hydrogen-containing compounds, such as a polyol and/... | 02/24/2009 |
| 7414154 | Polyamine compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-effects of chemoth... | 08/19/2008 |
| 7388033 | Amine-functionalized polyisobutylenes for improved hydrophobizing microemulsions In one embodiment, the present invention relates to amine-functionalized polyisobutylenes. Methods for preparing the amine-functionalized polyisobutylenes are also described. Furthermore, the invention relates to microemulsion coating compositions comprising the ami... | 06/17/2008 |
| 7387768 | Method for purifying gases The invention relates to the use of an absorption liquid for purifying gases from gaseous acidic contaminants, the absorption liquid comprising A) 0.1 to 100% by weight of one or more amines of the formula I ... | 06/17/2008 |
| 7385076 | Process for the preparation of phenylcarbamates A process for the preparation of compound of formula (I); wherein R1 is hydrogen, linear, branched or cyclic lower alkyl, cyclohexyl, allyl, propargyl or benzyl; R2 is hydrogen, methyl, ethyl or propyl; or R1 and R2 togeth... | 06/10/2008 |
| 7323594 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/29/2008 |
| 7314959 | Amino thiol compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine and amino thiol compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-ef... | 01/01/2008 |
| 7307184 | Processes for preparing oxazolidinone derivatives of β-hydroxyethlamine compounds and for preparing β-hydroxyethlamine compounds The present invention provides a process of starting from N-alkoxycarbonyl-ethylamine compounds having a leaving group at the β-position to prepare oxazolidinone derivatives of β-hydroxyethylamine compounds having an inverted steric configuration at the β-positio... | 12/11/2007 |
| 7217847 | Method for the production of optically active 2-amino 2-chloro, 2 hydroxy or 2-alkoxy-1-alcohols The invention relates to a process for preparing optically active 2-amino-, 2-chloro-, 2-hydroxy- or 2-alkoxy-1-alcohols by catalytically hydrogenating appropriate optically active 2-amino-, 2-chloro-, 2-hydroxy- and 2-alkoxycarboxylic acids or their acid derivative... | 05/15/2007 |
| 7211695 | β2-adrenergic receptor agonists Disclosed are multibinding compounds which are β2-adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.... | 05/01/2007 |
| 7195782 | Concentrated aqueous bromine solutions and their preparation Described is a process of producing a concentrated liquid biocide formulation. Mixed together are (a) bromine chloride or bromine and (b) an aqueous solution of alkali metal salt of sulfamic acid having a pH of at least about 7, in amounts such that (i) the active b... | 03/27/2007 |
| 7169818 | Lysophosphatidic acid receptor agonists and antagonists The present invention is directed to compositions comprising lysophosphatidic acid analogs and methods of using such analogs as agonist or antagonists of LPA receptor activity. In addition the invention is directed to LPA receptor agonists that vary in the degree of... | 01/30/2007 |
| 7166745 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/23/2007 |
| 7166748 | Durable coating compositions containing novel aspartic amine compounds A coating composition comprising a binder of a. polyisocyanate crosslinking agent; b. an isocyanate-reactive component having at least one compound having the following formula (I) including isomers and mixtures of... | 01/23/2007 |
| 7164034 | Alpha2delta ligands for fibromyalgia and other disorders This invention relates to a method of treating a disorder selected from OCD, agoraphobia, agoraphobia without history of panic disorder, specific phobia, social phobia, PTSD, restless legs syndrome, premenstrual dysphoric disorder, hot flashes, and fibromyalgia by a... | 01/16/2007 |
| 7157488 | N-(2-Arylethyl) benzylamines as antagonists of the 5-HTreceptor The present invention provides compounds of formula I pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are antagonists of the 5-HT6 receptor. The present invent... | 01/02/2007 |
| 7145039 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 12/05/2006 |
| 7138547 | Antitumoral compounds New spisulosine derivatives of use in treating tumors are of the formula (I) wherein: each X is the same or different, and represents H, OH, OR′, SH, SR′, SOR′, SO2R′, NO2, NH2, NHR′, N(R′)2, CN, halogen, C(═... | 11/21/2006 |
| 7087251 | Control of biofilm A method of eradicating or at least substantially reducing biofilm on a surface in contact with water, or which comes in contact with water, which method comprises introducing into such water a concentrated aqueous biocidal composition formed from bromine chloride a... | 08/08/2006 |
| 7060731 | Use of amines This application relates to the use of certain amines of formula (I) for combatting and preventing systemic and local complement activation, and in particular to the use of meglumine and derivatives and optionall... | 06/13/2006 |
| 7049472 | Bis(3-alkoxyalkan-2-OL) sulfides, sulfones, and sulfoxides: new surface active agents Compositions containing surfactant compounds according to formula (I) ROCH2CH(OH)CR1R2ZCR1R2CH(OH)CH2OR, (I) wherein Z is S, SO, or SO2, can have a range of equilib... | 05/23/2006 |
| 7049446 | Process for chemical reaction of amino acids and amides yielding selective conversion products The invention relates to processes for converting amino acids and amides to desirable conversion products including pyrrolidines, pyrrolidinones, and other N-substituted products. L-glutamic acid and L-pyroglutamic acid provide general reaction pathways to numerous ... | 05/23/2006 |
| 7034176 | Aminopropylphosphinic acids Intermediates used in the preparation of compounds of formula I, or a stereoisomer thereof, or a pharmaceutically acceptable form of either selected from the group consisting of a salt, a solvate and a combination there... | 04/25/2006 |
| 7026515 | Optically active amine derivatives and preparation process therefor A readily available and inexpensive natural α-amino acid is converted into a compound represented by formula (1), which is then reacted with an organometallic reagent represented by formula (2) to give an optically active 5-hydroxyoxazolidine represented by formula... | 04/11/2006 |
| 6960683 | Salt forms of poorly soluble probucol esters and ethers Organic amine salts of compounds of the formula: and their pharmaceutically acceptable salts, and uses in medical therapy are provided. ... | 11/01/2005 |
| 6919364 | Microbiological control in animal processing Fecal bacterial contamination in an animal is reduced by providing it with drinking water containing a microbiocidally-effective amount of halogen-based microbiocide resulting from mixing with water (A) a product formed in water from (i) bromine, chlorine, or bromin... | 07/19/2005 |
| 6916948 | Bis(1,3-dihydroxy-prop-2-yl) amine and derivatives thereof in the manufacture of polymers Derivatives of bis-(1,3-dihydroxy-prop-2-yl)amine are disclosed, together with the use of such derivatives and of bis(1,3-dihydroxy-prop-2-yl)amine itself in the preparation of polymers, in particular dendrimers. Some of the derivatives may be useful as non-ionic su... | 07/12/2005 |
| 6911281 | Non-aqueous electrolyte and electrochemical device comprising the same A non-aqueous electrolyte is disclosed, which comprises a non-aqueous solvent and a solute represented by the general formula(1): MBR1R2R3R4, wherein M is an alkali metal atom or an ammonium group and R1 to R | 06/28/2005 |
| 6909018 | Preparation of polyalkeneamines Polyalkeneamines of the formula (I) where R1, R2, R3, R4, R5 and R6 may have different meanings, are prepared by a process in which a polyalkene epoxide... | 06/21/2005 |
| 6908636 | Microbiological control in poultry processing In the processing of poultry, equipment, instruments, apparatus and/or water used in such processing, and/or carcasses and/or parts of poultry resulting from the processing of poultry, are disinfected with aqueous solutions of certain halogen-based microbiocides, es... | 06/21/2005 |
| 6888030 | Advances in amination Inclusion of a branched alcohol in the catalytic hydrogenation reaction involving an aliphatic nitro compound dramatically increases the efficiency of the conversion of nitro groups into amino groups. This discovery is of particular value in the production of polyal... | 05/03/2005 |
| 6852892 | Process for the synthesis of sphingosine This invention relates to a method for the production of a sphingoid base according to formula comprising the steps of (1) dissolving a starting compound according to formula III or a salt thereof in a sub... | 02/08/2005 |
| 6794545 | Conformationally restricted polyamine analogs as disease therapies Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of d... | 09/21/2004 |
| 6784175 | Use of substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compounds as medicaments The use of at least one substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compound and/or one of the enantiomers thereof and/or one of the diastereomers thereof and/or one of the physiologically acceptable salts thereof for producing a medi... | 08/31/2004 |
| 6765116 | Process of preparing a fluid rare earth alkoxylation catalyst A process to prepare an improved fluid rare earth phosphate catalyst composition useful in preparing alkylene oxide adducts of organic compounds having active hydrogen atoms is provided. The catalyst is prepared by dissolving a rare earth salt in a C9-C | 07/20/2004 |
| 6762325 | Method for production of alkoxylated compound When the reaction solution formed during the addition of an alkylene oxide to an active hydrogen-containing compound has viscosity of not less than 10 mPa·s, this invention provides a method for stirring the reaction solution by the rotation of a vane or vanes cont... | 07/13/2004 |
| 6747149 | Glucamine salts for treating hepatitis virus infections N-Substituted glucamine compounds of formula I are effective in treatment of hepatitis infections, including hepatitis B and hepatitis C. In treating hepatitis infections the compounds of formular I may be used alone, or in combinatioin with another antiviral agent ... | 06/08/2004 |
| 6713651 | β2-adrenergic receptor agonists Disclosed are multibinding compounds which are β2-adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, and bronchitis. They are also useful in the treatment of nervous system injury and premature labor.... | 03/30/2004 |
